Radioactive Decay

Radioactive decay is the spontaneous transformation of an unstable atomic nucleus into a more stable state, releasing particles or electromagnetic energy. The process can produce alpha particles, beta particles, or gamma rays, and each radioactive isotope decays at a characteristic rate described by its half-life, the time required for half of a sample to transform. In biology, radioactive decay supports radiometric dating of biological and geological materials, enables radioactive tracers to follow molecules and physiological processes, and provides targeted radiation for some cancer treatments. Understanding decay rates also helps researchers assess radiation exposure, manage isotopes safely, and interpret experimental measurements.

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JoVE Core - Chemistry

Radioactive Decay and Radiometric Dating

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2020

Radioactivity is a spontaneous disintegration of an unstable nuclide and is a random process, as all the nuclei in the sample do not decay simultaneously. The number of disintegrations per unit time is called the activity (A), which is directly proportional to the number of nuclei in the sample. The decay constant (λ) is an average probability of decay per nucleus in unit time. The SI unit for activity is the becquerel, which is one disintegration per second. Another unit of activity is the...

Radioactivity and Nuclear Equations

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2020

Nuclear chemistry is the study of reactions that involve changes in nuclear structure. The nucleus of an atom is composed of protons and, except for hydrogen, neutrons. The number of protons in the nucleus is called the atomic number (Z) of the element, and the sum of the number of protons and the number of neutrons is the mass number (A). Atoms with the same atomic number but different mass numbers are isotopes of the same element. A nuclide of an element has a specific number of protons and...

Types of Radioactivity

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2020

The most common types of radioactivity are α decay, β decay, γ decay, neutron emission, and electron capture. Alpha (α) decay is the emission of an α particle from the nucleus. For example, polonium-210 undergoes α decay: Alpha decay occurs primarily in heavy nuclei (A > 200, Z > 83). Loss of an α particle gives a daughter nuclide with a mass number four units smaller and an atomic number two units smaller than those of the parent nuclide. Beta (β) decay is the emission of an electron or...

Nonsense-mediated mRNA Decay

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2020

The Upf proteins that carry out nonsense-mediated decay (NMD) are found in all eukaryotic organisms, including humans. Each protein has an individual role, but they need to work in collaboration. Upf1 is an ATP-dependent RNA helicase that unwinds the RNA helix. Because Upf1 can unwind any RNA, Upf2 and Upf3 are required to help Upf1 discriminate between nonsense and normal mRNAs. Usually, Upf3 binds to an Exon Junction Complex (EJC) at mRNA splice sites. If a ribosome fully translates the mRNA,...

Interference and Decay

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2025

Forgetting is a complex cognitive phenomenon influenced by several factors, among which interference and decay are particularly prominent. These processes explain why individuals often struggle to retrieve specific information from memory, leading to lapses in recall that can be observed in everyday situations. Interference occurs when competing memories hinder the retrieval of particular information. It can be classified into two types: proactive and retroactive interference. Proactive...

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