Tibia Fibula

The tibia and fibula are the two long bones of the lower leg, forming a framework that supports movement and stabilizes the knee and ankle. The tibia is the larger, weight-bearing bone and articulates with the femur and talus, while the slender fibula runs parallel to it, anchors muscles, and contributes to ankle stability; the two bones are connected by an interosseous membrane. Together, their aligned shafts and joint surfaces transmit forces during standing, walking, and running. Studying the tibia and fibula helps explain lower-limb biomechanics, fracture patterns, growth, and the effects of injury on mobility.

Tibia Fibula - Related Videos

Education

JoVE Core - Anatomy and Physiology

Bones of the Lower Limb: Tibia and Fibula

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2025

The tibia is the main weight-bearing bone of the lower leg. It is larger than the fibula with which it is paired. The tibia is also the second longest bone in the body and is located right below the skin. The proximal end of the tibia forms the medial and the lateral condyle, which articulates with the condyles of the femur to form the knee joint. Between the articulating surfaces is the irregular elevated area known as the intercondylar eminence that serves as the inferior attachment point for...

Research

JoVE EoE - Immune Systems and Components

Isolation and Culture of Bone Marrow Stromal Cells from a Mouse Tibia

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2025

In this video, we demonstrate the isolation and culture of bone marrow stromal cells from the long bones of mice. The isolated adherent BMSCs can be used for further analysis.

Surgical Bone Implantation Technique for Rat Tibia Models of Diabetes and Osteoporosis

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Cited by 2 •

2024

The placement of implants in a rat model is an essential experimental procedure for clinical research. This study presents a comprehensive surgical protocol for implanting titanium implants into the tibia of rat models with diabetes and osteoporosis.

Ankle Exam

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2023

Source: Robert E. Sallis, MD. Kaiser Permanente, Fontana, California, USA The ankle and foot provide the foundation for the body and the stability needed for upright posture and ambulation. Because of its weight-bearing function, the ankle joint is a common site of injury among athletes and in the general population. Ankle injuries occur as a result of both acute trauma and repetitive overuse (such as running). The ankle is a fairly simple joint, consisting of the articulation between the...

Generation and Identification of GM-CSF Derived Alveolar-like Macrophages and Dendritic Cells From Mouse Bone Marrow

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Cited by 18 •

2016

Bone marrow cells cultured with granulocyte macrophage colony stimulating factor (GM-CSF) generate a heterogeneous culture containing macrophages and dendritic cells (DCs). This method highlights using MHCII and hyaluronan (HA) binding to differentiate macrophages from the DCs in the GM-CSF culture. Macrophages in this culture have many similarities to alveolar macrophages.

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