Defibrillation

Defibrillation is an emergency treatment that delivers a controlled electrical shock to the heart to stop life-threatening ventricular fibrillation or pulseless ventricular tachycardia and restore an organized rhythm. The shock simultaneously depolarizes a critical mass of cardiac muscle, interrupting disordered electrical activity so the heart’s normal pacemaker and conduction system can resume control; unlike cardioversion, defibrillation is not synchronized to a specific part of the cardiac cycle. In clinical care, automated external defibrillators and manual defibrillators guide shock delivery alongside cardiopulmonary resuscitation, making rapid recognition and treatment essential for improving outcomes after cardiac arrest.

Defibrillation - Related Videos

Research

JoVE Journal - Medicine
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Porcine Cardiac Arrest Model Using an Implantable Defibrillator

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2026

This protocol demonstrates the use of an implantable cardioverter-defibrillator (ICD) to reliably induce ventricular arrhythmias, perform internal cardioversion, and obtain intracardiac ECG recordings in a porcine model.

Research

JoVE Journal - Medicine
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A New Single Chamber Implantable Defibrillator with Atrial Sensing: A Practical Demonstration of Sensing and Ease of Implantation

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Cited by 5 •

2012

Dual-chamber implantable cardioverter-defibrillators (ICDs) may improve detection of atrial fibrillation as well as differentiation of tachycardias. However, this advantage is undermined by complications associated with the second electrode, which is required in conventional dual chamber devices. Therefore, BIOTRONIK has developed a new electrode called the LinoxSMART S DX that, when used in conjunction with the Lumax DX ICD, offers dual-chamber detection without the risks associated with the...

Education

JoVE Science Education - Clinical Skills
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Basic Life Support: Cardiopulmonary Resuscitation and Defibrillation

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2015

Source: Julianna Jung, MD, FACEP, Associate Professor of Emergency Medicine, The Johns Hopkins University School of Medicine, Maryland, USA High-quality cardiopulmonary resuscitation (CPR) is the single most important determinant of intact survival in cardiac arrest, and it is critical that all healthcare workers are able to perform this lifesaving technique effectively. Despite the conceptual simplicity of CPR, the reality is that many providers perform it incorrectly, resulting in suboptimal...

Research

JoVE Journal - Medicine

A Rat Model of Ventricular Fibrillation and Resuscitation by Conventional Closed-chest Technique

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Cited by 26 •

2015

This article describes a rat model of electrically-induced ventricular fibrillation and resuscitation by chest compression, ventilation, and delivery of electrical shocks that simulates an episode of sudden cardiac arrest and conventional cardiopulmonary resuscitation. The model enables gathering insights on the pathophysiology of cardiac arrest and exploration of new resuscitation strategies.

Basic Life Support Part II: Airway/Breathing and Continued Cardiopulmonary Resuscitation

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2023

Source: Julianna Jung, MD, FACEP, Associate Professor of Emergency Medicine, The Johns Hopkins University School of Medicine, Maryland, USA High-quality cardiopulmonary resuscitation (CPR) and defibrillation are the most important interventions for patients with cardiac arrest, and should be the first steps that rescuers perform. This is reflected in the American Heart Association's new "CAB" mnemonic. While rescuers were once taught the "ABCs" of cardiac arrest, they now learn "CAB" -...

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