Hypertrophic Pharyngitis

Hypertrophic pharyngitis is a chronic inflammatory condition in which the pharyngeal mucosa becomes thickened and irregular, often causing persistent throat discomfort and making it clinically important to distinguish from other throat disorders. Repeated irritation, such as from tobacco smoke, gastroesophageal reflux, infection, or postnasal drainage, can promote mucosal edema, vascular congestion, and lymphoid tissue enlargement, producing a granular or cobblestone appearance. Clinical assessment typically combines symptom history with examination of the pharynx to identify contributing factors and exclude more serious disease. Treatment focuses on addressing the underlying cause, reducing irritation, and monitoring persistent or progressive findings.

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JoVE Core - Medical-Surgical Nursing

Acute Pharyngitis

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2025

Introduction Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice. Classification Acute pharyngitis can be categorized based on its underlying cause: • Viral: Accounting for 40% to 60% of cases, viral infections are the most prevalent cause. Common cold viruses, influenza, adenovirus, and Epstein-Barr virus (mononucleosis) are among the most...

Chronic Pharyngitis

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2025

Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa. Etiology It often arises from persistent viral or bacterial infections affecting sinuses and tonsils. Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...

Streptococcal Pharyngitis

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2026

Streptococcal pharyngitis, commonly known as “strep throat,” is an acute infection of the oropharyngeal tissues caused by the Gram‑positive Group A Streptococcus (Streptococcus pyogenes). Transmission occurs primarily through respiratory droplets expelled during coughing, sneezing, or talking.Mechanisms of Host Entry and Immune EvasionUpon entering the host, S. pyogenes adheres to the mucosal epithelial cells of the pharynx via surface proteins, notably lipoteichoic acid and the antiphagocytic...

Research

JoVE Journal - Developmental Biology

Ex Vivo Culture of Pharyngeal Arches to Study Heart and Muscle Progenitors and Their Niche

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Cited by 5 •

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Here, we present a protocol to culture pharyngeal arches to study the biology of heart and muscle progenitor cells and their microenvironment.

Cardiomyopathy III: Hypertrophic Cardiomyopathy

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2025

Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...

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