Orthopedic Implant Design

Orthopedic implant design is the engineering process of developing devices that restore or support the function of bones, joints, and other musculoskeletal structures. It combines anatomy, biomechanics, materials science, and manufacturing to shape implants that transfer physiological loads, resist wear and corrosion, and achieve stable fixation through bone integration or mechanical attachment. Engineers use imaging, computational modeling, and mechanical testing to evaluate fit, strength, stiffness, and long-term performance before clinical use. These principles guide hip and knee replacements, fracture-fixation devices, spinal implants, and patient-specific solutions, helping improve mobility, reduce complications, and extend implant service life.

Orthopedic Implant Design - Related Videos

Research

JoVE Journal - Biology
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Bioelectric Analyses of an Osseointegrated Intelligent Implant Design System for Amputees

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Cited by 16 •

2009

There is a need to develop alternative prosthesis attachment due to limb loss attributed to vascular occlusive diseases and trauma. The goal of the work is to introduce an osseointegrated intelligent implant design system to increase skeletal fixation and reduce periprosthetic infection rates for patients needing osseointegrated technology.

Research

JoVE Journal - Bioengineering

A Neural Implant Design Toolbox for Nonhuman Primates

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Cited by 2 •

2024

This paper outlines automated processes for nonhuman primate neurosurgical planning based on magnetic resonance imaging (MRI) scans. These techniques use procedural steps in programming and design platforms to support customized implant design for NHPs. The validity of each component can then be confirmed using three-dimensional (3D) printed life-size anatomical models.

Mesenchymal Stromal Cell Culture and Delivery in Autologous Conditions: A Smart Approach for Orthopedic Applications

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Cited by 28 •

2016

Culturing human Mesenchymal Stromal Cells (hMSCs) with autologous serum, reduces the risks of rejection by xenogeneic material and other negative effects. It also allows for the recovery of a subset of mesodermal progenitors, which can deliver fresh hMSCs. Embedding hMSCs in an autologous fibrin clot enables easy handling and effective surgical implantation.

Research

JoVE Journal - Medicine
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Techniques for Processing Eyes Implanted with a Retinal Prosthesis for Localized Histopathological Analysis: Part 2 Epiretinal Implants with Retinal Tacks

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Cited by 23 •

2015

Here we describe histological techniques for visualising ocular tissue directly adjacent to a metal epiretinal tack and retinal prosthesis.

Animal Model of Implant-Associated Infections in Mice

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2025

The present protocol describes a mouse model employing subcutaneous dorsal implantation to investigate implant-associated infections, enabling comprehensive investigation of pathophysiological mechanisms and supporting the development of diagnostic criteria with targeted therapeutic strategies.

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