Paper Folding

Paper folding is the physical act of bending a sheet to create creases, shapes, and layered structures, and it provides a tangible way to study geometric relationships. In mathematics, each fold can be modeled as a reflection across a crease line, allowing learners to investigate symmetry, angles, perpendicularity, intersections, and the division of lengths or areas without relying solely on drawn figures. Mathematical paper folding supports geometric construction, proof, spatial reasoning, and problem solving, while origami-inspired models connect plane geometry with three-dimensional form. It also offers an accessible setting for testing conjectures and visualizing abstract concepts.

Paper Folding - Related Videos

Education

JoVE Science Education - Information Literacy

Reading Research Papers

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2026

Research articles are structured documents designed to communicate scientific findings efficiently and transparently. Rather than reading them sequentially like a narrative, readers can approach them strategically by understanding their standardized organization. Evaluating the title, authors, and institutional affiliations provides an initial indication of relevance, expertise, and credibility. The Abstract offers a concise summary of the study’s objective, methodology, and main findings,...

Research

JoVE Journal - Biochemistry

Paper-Based Preconcentration and Isolation of Microvesicles and Exosomes

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Cited by 4 •

2020

Presented is a protocol to fabricate a paper-based device for the effective enrichment and isolation of microvesicles and exosomes.

Molecular Chaperones and Protein Folding

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2020

The native conformation of a protein is formed by interactions between the side chains of its constituent amino acids. When the amino acids cannot form these interactions, the protein cannot fold by itself and needs chaperones. Notably, chaperones do not relay any additional information required for the folding of polypeptides; the native conformation of a protein is determined solely by its amino acid sequence. Chaperones catalyze protein folding without being a part of the folded protein. The...

A Paper-Based Immunoassay for the Detection of Immunoglobulin G

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2025

The video demonstrates a paper-based immunoassay, involving amine-functionalized cellulose discs cross-linked with glutaraldehyde. Covalent immobilization of IgG-Fc-specific capture antibodies, followed by the introduction of immunoglobulin G and horseradish peroxidase-conjugated detection antibodies, results in a color change confirming the presence of immunoglobulin G.

Protein Folding

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2020

Proteins are chains of amino acids linked together by peptide bonds. Upon synthesis, a protein folds into a three-dimensional conformation which is critical to its biological function. Interactions between its constituent amino acids guide protein folding, and hence the protein structure is primarily dependent on its amino acid sequence.Protein Structure Is Critical to Its Biological FunctionProteins perform a wide range of biological functions such as catalyzing chemical reactions, providing...

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