Intrauterine Pregnancy
Intrauterine Pregnancy - Related Videos
07:03
Intrauterine Telemetry to Measure Mouse Contractile Pressure In Vivo
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Cited by 16 •
2015
This manuscript provides a protocol for implanting telemeters in the mouse for the purpose of measuring intrauterine pressures during pregnancy.
04:08
Mouse Model of Surgical Uterine Injury and Subsequent Pregnancy Outcomes
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2025
This protocol describes a procedure for inducing uterine injury in a mouse model, followed by downstream analyses during a subsequent pregnancy.
06:19
A Rat Model of Mild Intrauterine Hypoperfusion with Microcoil Stenosis
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Cited by 18 •
2018
Mild intrauterine hypoperfusion was produced by artery stenosis with metal microcoils wrapped around the uterine and ovarian arteries in rats at embryonic day 17. This procedure produced prenatal hypoperfusion and intrauterine growth restriction.
04:11
High-frequency Ultrasonography Based Early Pregnancy Characterization: A Technique to Study Embryo Implantation and Pregnancy Progression in Pregnant Murine Model
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2025
In this video, we demonstrate high-frequency ultrasonography to image embryo implantation sites in a pregnant murine model. This imaging technique successfully detects viable pregnancy and characterizes embryo-implantation sites during early murine pregnancy.
07:04
A Novel Use of Three-dimensional High-frequency Ultrasonography for Early Pregnancy Characterization in the Mouse
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Cited by 5 •
2017
Mice are widely used to study gestational biology. However, pregnancy termination is required for such studies which precludes longitudinal investigations and necessitates the use of large numbers of animals. Therefore, we describe a non-invasive technique of high-frequency ultrasonography for early detection and monitoring of post-implantation events in the pregnant mouse.
FAQs
After implantation, human chorionic gonadotropin and progesterone help sustain development. Human chorionic gonadotropin is an early pregnancy signal, while progesterone supports the hormonal environment associated with continued gestation. Together, these signals help maintain the developing pregnancy as the gestational sac, placenta, and supporting tissues form, making hormonal assessment relevant to evaluating early progression.
As early development proceeds, the gestational sac provides a recognizable structure, while the placenta and other supporting tissues develop to sustain the embryo. These features help clinicians evaluate whether development is occurring within the uterine setting and provide structural context alongside hormonal information during early pregnancy assessment.
This distinction is clinically important because implantation outside the uterine cavity represents a different pregnancy location and can signal a complication requiring timely management. Clinical assessment and ultrasound help determine location, allowing clinicians to separate expected intrauterine development from ectopic pregnancy and respond appropriately when early findings are concerning.
The endometrium is the prepared uterine lining to which the early embryo attaches after traveling through the fallopian tube. Its readiness provides the local setting for implantation and subsequent formation of the gestational sac, placenta, and supporting tissues. Assessing this sequence helps place early pregnancy development in its uterine context.
Clinicians combine clinical assessment with ultrasound to locate the pregnancy and evaluate early gestational development. This approach can show whether findings are consistent with intrauterine development, support estimation of pregnancy age, and help distinguish a normal implantation from ectopic pregnancy. The resulting information guides prenatal care and attention to possible complications.
Ultrasound contributes to pregnancy-age estimation by providing an assessment of early gestational development rather than relying on location alone. When interpreted with clinical assessment, it gives clinicians a fuller picture of the pregnancy’s stage and supports planning of prenatal care. This makes the examination useful even after intrauterine location has been established.
Identification provides a basis for evaluating early gestational development and organizing prenatal care. It also helps clinicians recognize when findings may not follow the expected intrauterine pattern, including situations in which complications require timely management. Thus, the assessment connects pregnancy-location findings with follow-up decisions rather than serving as an isolated diagnostic label.