Pancreatic Cystic Lesions

Pancreatic cystic lesions are fluid-filled abnormalities within or around the pancreas, ranging from benign, inflammation-related collections to precancerous or malignant cystic neoplasms. Their evaluation combines clinical history with imaging, particularly computed tomography, magnetic resonance imaging, and endoscopic ultrasound, which characterize features such as cyst communication with the pancreatic duct, wall nodules, septations, and duct dilation. Accurate classification helps distinguish lesions requiring surveillance from those that may benefit from surgical treatment, while fluid analysis and cytology obtained through endoscopic ultrasound can support diagnosis. Understanding these lesions improves early cancer risk assessment and guides individualized management.

Pancreatic Cystic Lesions - Related Videos

Research

JoVE Journal - Cancer Research

Robotic Duodenum-preserving Total Pancreatic Head Resection for Intraductal Papillary Mucinous Neoplasms

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2026

This protocol presents robotic duodenum-preserving total pancreatic head resection (R-DPPHRt) for intraductal papillary mucinous neoplasms (IPMNs). A video demonstrates the technique in a patient with main duct-IPMN, highlighting its feasibility as a minimally invasive, organ-preserving alternative to pancreaticoduodenectomy.

Research

JoVE Journal - Cancer Research
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Multianimal Magnetic Resonance Imaging for Tumor Measurements in Pancreatic Cancer Mouse Models

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2026

This protocol uses a multichamber bed for parallel magnetic resonance imaging (MRI) of up to four animals to detect pancreatic adenocarcinoma tumors in genetically engineered mouse models. This multianimal MRI protocol is fast and cost-effective for detecting and measuring tumors, facilitating animal selection for preclinical studies and longitudinal monitoring of tumor growth.

Treatment of Middle-segment Pancreatic Benign Tumor Using Laparoscopic Central Pancreatectomy with End-to-end Pancreatic Duct Reconstruction

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2026

This article presents laparoscopic central pancreatectomy with pancreatic duct end-to-end anastomosis as an important surgical approach for middle-segment pancreatic benign and low-grade malignant tumors.

Comparative Lesions Analysis Through a Targeted Sequencing Approach

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2019

This article describes a method to identify clonal and subclonal alterations among different specimens from a given patient. Although the experiments described here focus on a specific tumor type, the approach is broadly applicable to other solid tumors.

Laparoscopic Duodenum-Preserving Pancreatic Head Resection via Inferior Infracolic Approach: A Surgical Approach for Benign Lesions

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2024

This article provides a whole technical process of laparoscopic duodenum-preserving pancreatic head resection via an inferior infracolic approach. This is a surgical approach for benign tumors without intraoperative fluorescence image guidance.

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