Skin Conductance Reactivity

Skin conductance reactivity (SCR) is a physiological measure of rapid changes in the skin’s electrical conductance, commonly used to index sympathetic nervous system activity and autonomic arousal. When an emotionally salient, stressful, or attention-demanding stimulus activates sympathetic pathways, eccrine sweat glands increase skin moisture, lowering electrical resistance and producing a measurable conductance response. In neuroscience, researchers record SCR with electrodes, often alongside behavioral or neural measures, to study emotional processing, learning, attention, and stress without requiring a verbal report. Because responses reflect arousal rather than a specific emotion, SCR is most informative when interpreted with experimental context and complementary measures.

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Education

JoVE Science Education - Chemistry

Conducting Reactions Below Room Temperature

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2023

Source: Laboratory of Dr. Dana Lashley - College of William and Mary Demonstration by: Matt Smith When new bonds are formed in the course of a chemical reaction, it requires that the involved species (atoms or molecules) come in very close proximity and collide into one another. The collisions between these species are more frequent and effective the higher the speed at which these molecules are moving. A widely used rule of thumb, which has its roots in the Arrhenius equation1, states that...

Research

JoVE Journal - Medicine
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MRI Mapping of Cerebrovascular Reactivity via Gas Inhalation Challenges

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Cited by 79 •

2014

Non-invasive imaging of the brain vasculature’s ability to dilate or constrict may allow a better understanding of cerebrovascular pathophysiology in various neurological diseases. The present report describes a reproducible and patient-comfortable protocol to perform vascular reactivity imaging in humans using magnetic resonance imaging (MRI).

Detecting Reactive Oxygen Species

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2023

Reactive oxygen species are chemically active, oxygen-derived molecules capable of oxidizing other molecules. Because of their reactive nature, there are many deleterious effects associated with unchecked ROS production, including structural damage to DNA and other biological molecules. However, ROS can also be mediators of physiological signaling. There is accumulating evidence that ROS play significant roles in everything from activation of transcription factors to the mediation of...

Triggering Reactive Gliosis In Vivo by a Forebrain Stab Injury

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Cited by 8 •

2015

This article describes a detailed protocol to produce a forebrain stab injury in adult mice. The stab injury induces severe reactive gliosis and glial scar formation which can be subsequently examined by standard immunohistochemistry methods.

Conduct Disorder

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2025

Conduct disorder is a complex mental health diagnosis characterized by a repetitive and persistent pattern of behavior that violates societal norms, the rights of others, or age-appropriate rules. The diagnostic criteria for conduct disorder require the presence of at least three problematic behaviors within the past 12 months, with at least one occurring in the past six months. These behaviors are grouped into four categories: aggression toward people and animals; destruction of property;...

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