اختبار الكفاءة في المختبر وفي الجسم الحي للجسيمات النانوية mRNA-Lipid التي تمت صياغتها عن طريق خلط الموائع الدقيقة

Pre-Formulation Preparation

Preparation of the Lipid and Nucleic Acid Mixes

Microfluidic Formulation of mRNA-LNPs

Post-Formulation Processing and Characterization of the mRNA-LNPs

In Vitro Transfection of HepG2 Cells

In Vivo Evaluation of mRNA-LNPs in Mice Following Tail Vein Injection

Results: Formulation of mRNA-LNPs and the Assessment of In Vitro and In Vivo Performance

Conclusion