مقابلة : HIV - 1 الحمض النووي الختان Proviral باستخدام تطورت Recombinase

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Title

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Excision of proviral DNA. Targeting LTR specific sequences.

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Addressing the problem of multiple HIV isolates.

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Generation of site-specific Tre recombinase via directed molecular evolution.

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Delivery of Tre recombinase, HIV-1 proviral DNA excision, and elimination of HIV-1 viruses.

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Open questions.

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Towards a clinical application.