Uwe-Karsten Hanisch

Institute of Neuropathology, university of göttingen

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 32	2013

Other Publications

Article	Year
Microglia as a source and target of cytokines. Glia\| PubMed ID: 12379902	2002
Interferon-gamma differentially modulates the release of cytokines and chemokines in lipopolysaccharide- and pneumococcal cell wall-stimulated mouse microglia and macrophages. The European journal of neuroscience\| PubMed ID: 12473079	2002
Elevation of basal intracellular calcium as a central element in the activation of brain macrophages (microglia): suppression of receptor-evoked calcium signaling and control of release func... The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 12805281	2003
Purinergic receptors on microglial cells: functional expression in acute brain slices and modulation of microglial activation in vitro. The European journal of neuroscience\| PubMed ID: 12814360	2003
Expression of proteinase-activated receptors in mouse microglial cells. Neuroreport\| PubMed ID: 14663194	2003
Tyrosine kinase inhibition reduces inflammation in the acute stage of experimental pneumococcal meningitis. Infection and immunity\| PubMed ID: 15155632	2004
The tyrosine kinase inhibitor AG126 restores receptor signaling and blocks release functions in activated microglia (brain macrophages) by preventing a chronic rise in the intracellular calc... Journal of neurochemistry\| PubMed ID: 15255929	2004
The microglia-activating potential of thrombin: the protease is not involved in the induction of proinflammatory cytokines and chemokines. The Journal of biological chemistry\| PubMed ID: 15452111	2004
Microglia. Metabolic brain disease\| PubMed ID: 15554430	2004
c-Jun N-terminal kinases (JNKs) mediate pro-inflammatory actions of microglia. Glia\| PubMed ID: 15739188	2005
Unraveling thrombin's true microglia-activating potential: markedly disparate profiles of pharmaceutical-grade and commercial-grade thrombin preparations. Journal of neurochemistry\| PubMed ID: 16271051	2005
Microglial phenotype: is the commitment reversible? Trends in neurosciences\| PubMed ID: 16406093	2006
Activation of microglial cells by thrombin: past, present, and future. Seminars in thrombosis and hemostasis\| PubMed ID: 16673268	2006
A paediatric supratentorial primitive neuroectodermal tumour associated with malignant astrocytic transformation and a clonal origin of both components. Neurosurgical review\| PubMed ID: 17333087	2007
Fibronectin is elevated in the cerebrospinal fluid of patients suffering from bacterial meningitis and enhances inflammation caused by bacterial products in primary mouse microglial cell cul... Journal of neurochemistry\| PubMed ID: 17561936	2007
Lipopolysaccharide is a frequent and significant contaminant in microglia-activating factors. Glia\| PubMed ID: 17910052	2008
Microglia: active sensor and versatile effector cells in the normal and pathologic brain. Nature neuroscience\| PubMed ID: 17965659	2007
Microglia in the adult brain arise from Ly-6ChiCCR2+ monocytes only under defined host conditions. Nature neuroscience\| PubMed ID: 18026096	2007
Myelin-phagocytosing macrophages in isolated sciatic and optic nerves reveal a unique reactive phenotype. Glia\| PubMed ID: 18069669	2008
Toll-like receptors: roles in neuroprotection? Trends in neurosciences\| PubMed ID: 18329736	2008
Thrombin regulates CD40 expression in microglial cells. Neuroreport\| PubMed ID: 18418252	2008
Distinct and nonredundant in vivo functions of IFNAR on myeloid cells limit autoimmunity in the central nervous system. Immunity\| PubMed ID: 18424188	2008
Inhibition of Rho-dependent pathways by Clostridium botulinum C3 protein induces a proinflammatory profile in microglia. Glia\| PubMed ID: 18442097	2008
Thrombin-induced regulation of CD95(Fas) expression in the N9 microglial cell line: evidence for involvement of proteinase-activated receptor(1) and extracellular signal-regulated kinase 1/2... Neurochemical research\| PubMed ID: 18686031	2009
Toll-like receptor prestimulation increases phagocytosis of Escherichia coli DH5alpha and Escherichia coli K1 strains by murine microglial cells. Infection and immunity\| PubMed ID: 18981243	2009
FK506 protects against various immune responses and secondary degeneration following cerebral ischemia. Anatomical record (Hoboken, N.J. : 2007)\| PubMed ID: 19728359	2009
Fibronectin stimulates Escherichia coli phagocytosis by microglial cells. Glia\| PubMed ID: 19780198	2010
Toll-like receptor stimulation enhances phagocytosis and intracellular killing of nonencapsulated and encapsulated Streptococcus pneumoniae by murine microglia. Infection and immunity\| PubMed ID: 19933834	2010
Therapeutic and adverse effects of a non-steroidal glucocorticoid receptor ligand in a mouse model of multiple sclerosis. PloS one\| PubMed ID: 19997594	2009
TRPM3 is expressed in sphingosine-responsive myelinating oligodendrocytes. Journal of neurochemistry\| PubMed ID: 20163522	2010
Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 20231476	2010
T cell-dependence of Lassa fever pathogenesis. PLoS pathogens\| PubMed ID: 20360949	2010
Microglia promote colonization of brain tissue by breast cancer cells in a Wnt-dependent way. Glia\| PubMed ID: 20549749	2010
Inflammatory chemokine release of astrocytes in vitro is reduced by all-trans retinoic acid. Journal of neurochemistry\| PubMed ID: 20557428	2010
The viral TLR3 agonist poly(I:C) stimulates phagocytosis and intracellular killing of Escherichia coli by microglial cells. Neuroscience letters\| PubMed ID: 20599470	2010
Inflammatory cytokine release of astrocytes in vitro is reduced by all-trans retinoic acid. Journal of neuroimmunology\| PubMed ID: 20826012	2010
CD14 and TRIF govern distinct responsiveness and responses in mouse microglial TLR4 challenges by structural variants of LPS. Brain, behavior, and immunity\| PubMed ID: 20951794	2011
Selective transfer of exosomes from oligodendrocytes to microglia by macropinocytosis. Journal of cell science\| PubMed ID: 21242314	2011
Physiology of microglia. Physiological reviews\| PubMed ID: 21527731	2011
Expression of coagulation factors and their receptors in tumor tissue and coagulation factor upregulation in peripheral blood of patients with cerebral carcinoma metastases. Journal of cancer research and clinical oncology\| PubMed ID: 22065054	2012
Reduced astrocytic NF-ÎºB activation by laquinimod protects from cuprizone-induced demyelination. Acta neuropathologica\| PubMed ID: 22766690	2012
Complement receptor-3 negatively regulates the phagocytosis of degenerated myelin through tyrosine kinase Syk and cofilin. Journal of neuroinflammation\| PubMed ID: 22776089	2012
The nucleotide-binding oligomerization domain-containing-2 ligand muramyl dipeptide enhances phagocytosis and intracellular killing of Escherichia coli K1 by Toll-like receptor agonists in m... Journal of neuroimmunology\| PubMed ID: 22889567	2012
Toll-like receptor activation reveals developmental reorganization and unmasks responder subsets of microglia. Glia\| PubMed ID: 22911652	2012
Influence of methylene blue on microglia-induced inflammation and motor neuron degeneration in the SOD1(G93A) model for ALS. PloS one\| PubMed ID: 22952827	2012
Proteins in microglial activation--inputs and outputs by subsets. Current protein & peptide science\| PubMed ID: 23441901	2013
Resistance of the brain to Escherichia coli K1 infection depends on MyD88 signaling and the contribution of neutrophils and monocytes. Infection and immunity\| PubMed ID: 23478323	2013
Histone deacetylase inhibitors suppress immune activation in primary mouse microglia. Journal of neuroscience research\| PubMed ID: 23686642	2013
Functional diversity of microglia - how heterogeneous are they to begin with? Frontiers in cellular neuroscience\| PubMed ID: 23717262	2013
Carcinoma cells misuse the host tissue damage response to invade the brain. Glia\| PubMed ID: 23832647	2013
Empty liposomes induce antitumoral effects associated with macrophage responses distinct from those of the TLR1/2 agonist Pam3CSK 4 (BLP). Cancer immunology, immunotherapy : CII\| PubMed ID: 23917775	2013
Toll-like receptor 2 mediates microglia/brain macrophage MT1-MMP expression and glioma expansion. Neuro-oncology\| PubMed ID: 24014382	2013
Zoledronic acid inhibits macrophage/microglia-assisted breast cancer cell invasion. Oncotarget\| PubMed ID: 24036536	2013