Tobin J. Dickerson

Department of Chemistry, The Scripps Research Institute

Affiliated withThe Scripps Research Institute

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 4	2013

Other Publications

Article	Year
Aqueous aldol catalysis by a nicotine metabolite. Journal of the American Chemical Society\| PubMed ID: 11916401	2002
Soluble polymers as scaffolds for recoverable catalysts and reagents. Chemical reviews\| PubMed ID: 12371887	2002
A previously undescribed chemical link between smoking and metabolic disease. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12403823	2002
High-resolution diffusion-ordered spectroscopy to probe the microenvironment of JandaJel and Merrifield resins. The Journal of organic chemistry\| PubMed ID: 12713377	2003
Glycation of the amyloid beta-protein by a nicotine metabolite: a fortuitous chemical dynamic between smoking and Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12815102	2003
Catalysis of the photo-Fries reaction: antibody-mediated stabilization of high energy states. Journal of the American Chemical Society\| PubMed ID: 14664584	2003
Antibody-catalyzed oxidative degradation of nicotine using riboflavin. Bioorganic & medicinal chemistry\| PubMed ID: 15336277	2004
Immunological consequences of methamphetamine protein glycation. Journal of the American Chemical Society\| PubMed ID: 15366884	2004
Nornicotine aqueous aldol reactions: synthetic and theoretical investigations into the origins of catalysis. The Journal of organic chemistry\| PubMed ID: 15387581	2004
A precipitator for the detection of thiophilic metals in aqua. Journal of the American Chemical Society\| PubMed ID: 15600364	2004
Revisiting quorum sensing: Discovery of additional chemical and biological functions for 3-oxo-N-acylhomoserine lactones. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15623555	2005
Enantioreversal in the sharpless asymmetric epoxidation reaction controlled by the molecular weight of a covalently appended achiral polymer. The Journal of organic chemistry\| PubMed ID: 15730294	2005
Hammett correlation of nornicotine analogues in the aqueous aldol reaction: implications for green organocatalysis. The Journal of organic chemistry\| PubMed ID: 15845010	2005
Bacteriophage-mediated protein delivery into the central nervous system and its application in immunopharmacotherapy. Expert opinion on biological therapy\| PubMed ID: 15952908	2005
Toward cocaine esterase therapeutics. Journal of the American Chemical Society\| PubMed ID: 16011362	2005
Altered retinoid homeostasis catalyzed by a nicotine metabolite: implications in macular degeneration and normal development. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16014706	2005
Vitamin B2-mediated cellular photoinhibition of botulinum neurotoxin A. FEBS letters\| PubMed ID: 16198354	2005
Discovery of acetylcholinesterase peripheral anionic site ligands through computational refinement of a directed library. Biochemistry\| PubMed ID: 16274232	2005
A site-specific bifunctional protein labeling system for affinity and fluorescent analysis. Bioconjugate chemistry\| PubMed ID: 16287229	2005
Structure of the Escherichia coli quorum sensing protein SdiA: activation of the folding switch by acyl homoserine lactones. Journal of molecular biology\| PubMed ID: 16307757	2006
Recent advances for the treatment of cocaine abuse: central nervous system immunopharmacotherapy. The AAPS journal\| PubMed ID: 16353936	2005
Complete reaction cycle of a cocaine catalytic antibody at atomic resolution. Structure (London, England : 1993)\| PubMed ID: 16472740	2006
Emerging chemical and biological approaches for the preparation of discovery libraries. Drug discovery today\| PubMed ID: 16533712	2006
Superactivation of the botulinum neurotoxin serotype A light chain metalloprotease: a new wrinkle in botulinum neurotoxin. Journal of the American Chemical Society\| PubMed ID: 16568962	2006
Enamine-based aldol organocatalysis in water: are they really "all wet"? Angewandte Chemie (International ed. in English)\| PubMed ID: 17001595	2006
Unexpected acetylcholinesterase activity of cocaine esterases. Journal of the American Chemical Society\| PubMed ID: 17131989	2006
A molecular link between the active component of marijuana and Alzheimer's disease pathology. Molecular pharmaceutics\| PubMed ID: 17140265	2006
The use of small molecules to investigate molecular mechanisms and therapeutic targets for treatment of botulinum neurotoxin A intoxication. ACS chemical biology\| PubMed ID: 17163773	2006
An in vitro and in vivo disconnect uncovered through high-throughput identification of botulinum neurotoxin A antagonists. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17293454	2007
Technological advancements for the detection of and protection against biological and chemical warfare agents. Chemical Society reviews\| PubMed ID: 17325785	2007
Antibody-catalyzed oxidation of delta(9)-tetrahydrocannabinol. Journal of the American Chemical Society\| PubMed ID: 17335216	2007
Positional linker effects in haptens for cocaine immunopharmacotherapy. Bioorganic & medicinal chemistry letters\| PubMed ID: 17531484	2007
Self-vaccination by methamphetamine glycation products chemically links chronic drug abuse and cardiovascular disease. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17592122	2007
Phage escape libraries for checkmate analysis. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17646645	2007
NMR detection of adventitious xylose binding to the quorum-sensing protein SdiA of Escherichia coli. Bioorganic & medicinal chemistry letters\| PubMed ID: 17889538	2007
Synthesis and structure-activity relationships of second-generation hydroxamate botulinum neurotoxin A protease inhibitors. Bioorganic & medicinal chemistry letters\| PubMed ID: 17951059	2007
Investigating novel therapeutic targets and molecular mechanisms to treat botulinum neurotoxin A intoxication. Future microbiology\| PubMed ID: 18041908	2007
Biologically templated organic polymers with nanoscale order. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18216240	2008
Nornicotine-organocatalyzed aqueous reduction of alpha,beta-unsaturated aldehydes. Chemical communications (Cambridge, England)\| PubMed ID: 18361380	2007
Interspecies and interkingdom communication mediated by bacterial quorum sensing. Chemical Society reviews\| PubMed ID: 18568160	2008
Major sperm protein as a diagnostic antigen for onchocerciasis. Bioorganic & medicinal chemistry\| PubMed ID: 18632276	2008
The strange case of the botulinum neurotoxin: using chemistry and biology to modulate the most deadly poison. Angewandte Chemie (International ed. in English)\| PubMed ID: 18844202	2008
Prevention of drug-induced memory impairment by immunopharmacotherapy. Journal of medicinal chemistry\| PubMed ID: 18921991	2008
Function-oriented synthesis applied to the anti-botulinum natural product toosendanin. Bioorganic & medicinal chemistry\| PubMed ID: 19131252	2009
Predicting protein evolution in vitro by phage escape technology. Molecular bioSystems\| PubMed ID: 19156257	2009
Bimodal modulation of the botulinum neurotoxin protein-conducting channel. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19164566	2009
Drugs of abuse that mediate advanced glycation end product formation: a chemical link to disease pathology. Accounts of chemical research\| PubMed ID: 19275211	2009
Monoclonal antibodies with orthogonal azaspiracid epitopes. Chembiochem : a European journal of chemical biology\| PubMed ID: 19492388	2009
A critical evaluation of a nicotine vaccine within a self-administration behavioral model. Molecular pharmaceutics\| PubMed ID: 20104903	2010
A bacteriophage-based platform for rapid trace detection of proteases. Journal of the American Chemical Society\| PubMed ID: 20812737	2010
Metabolomics-based discovery of diagnostic biomarkers for onchocerciasis. PLoS neglected tropical diseases\| PubMed ID: 20957145	2010
Characterization of differences between blood sample matrices in untargeted metabolomics. Analytical chemistry\| PubMed ID: 21175165	2011
Enhancing the Pharmacokinetic Properties of Botulinum Neurotoxin Serotype A Protease Inhibitors Through Rational Design. ACS chemical neuroscience\| PubMed ID: 21743830	2011
Sensing the deadliest toxin: technologies for botulinum neurotoxin detection. Toxins\| PubMed ID: 22069545	2010
A coincidence detector triggers botulinum neurotoxin translocation. Future microbiology\| PubMed ID: 22324987	2012
Reexamining hydroxamate inhibitors of botulinum neurotoxin serotype A: extending towards the β-exosite. Bioorganic & medicinal chemistry letters\| PubMed ID: 22542019	2012
Contrasting effects of d-methamphetamine, 3,4-methylenedioxymethamphetamine, 3,4-methylenedioxypyrovalerone, and 4-methylmethcathinone on wheel activity in rats. Drug and alcohol dependence\| PubMed ID: 22664136	2012
Effect of ambient temperature on the thermoregulatory and locomotor stimulant effects of 4-methylmethcathinone in Wistar and Sprague-Dawley rats. PloS one\| PubMed ID: 22952999	2012
Mephedrone (4-methylmethcathinone) supports intravenous self-administration in Sprague-Dawley and Wistar rats. Addiction biology\| PubMed ID: 23363010	2013
Microsphere-based immunoassay for the detection of azaspiracids. Analytical biochemistry\| PubMed ID: 24215909	2013