Robert L. Medcalf

Australian Centre for Blood Diseases, Monash University

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 16	2013

Other Publications

Article	Year
Plasminogen activator inhibitor type 2: a regulator of monocyte proliferation and differentiation. Blood\| PubMed ID: 11929770	2002
Prothrombin G20210A is a bifunctional gene polymorphism. Thrombosis and haemostasis\| PubMed ID: 12038788	2002
Vampire bat salivary plasminogen activator (desmoteplase): a unique fibrinolytic enzyme that does not promote neurodegeneration. Stroke; a journal of cerebral circulation\| PubMed ID: 12574572	2003
Inherent instability of plasminogen activator inhibitor type 2 mRNA is regulated by tristetraprolin. The Journal of biological chemistry\| PubMed ID: 12578825	2003
The structure of the zinc finger domain from human splicing factor ZNF265 fold. The Journal of biological chemistry\| PubMed ID: 12657633	2003
The t-PA -7351C>T enhancer polymorphism decreases Sp1 and Sp3 protein binding affinity and transcriptional responsiveness to retinoic acid. Blood\| PubMed ID: 15466927	2005
The relationship between the prothrombin upstream sequence element and the G20210A polymorphism: the influence of a competitive environment for mRNA 3'-end formation. Nucleic acids research\| PubMed ID: 15718300	2005
Transcriptional and posttranscriptional regulation of the plasminogen activator system. Thrombosis and haemostasis\| PubMed ID: 15841310	2005
Vampire bat salivary plasminogen activator (desmoteplase) inhibits tissue-type plasminogen activator-induced potentiation of excitotoxic injury. Stroke; a journal of cerebral circulation\| PubMed ID: 15879331	2005
Regulation of protease and protease inhibitor gene expression: the role of the 3'-UTR and lessons from the plasminogen activating system. Progress in nucleic acid research and molecular biology\| PubMed ID: 16164975	2005
Meet the serpins. The FEBS journal\| PubMed ID: 16176257	2005
The undecided serpin. The ins and outs of plasminogen activator inhibitor type 2. The FEBS journal\| PubMed ID: 16176260	2005
Tissue-type plasminogen activator: a multifaceted modulator of neurotransmission and synaptic plasticity. Neuron\| PubMed ID: 16731507	2006
SerpinB2 is an inducible host factor involved in enhancing HIV-1 transcription and replication. The Journal of biological chemistry\| PubMed ID: 16923810	2006
Oncostatin M is a neuroprotective cytokine that inhibits excitotoxic injury in vitro and in vivo. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 17023520	2006
Stage specific gene expression of serpins and their cognate proteases during myeloid differentiation. British journal of haematology\| PubMed ID: 17107353	2006
Two conserved regions within the tissue-type plasminogen activator gene promoter mediate regulation by brain-derived neurotrophic factor. The FEBS journal\| PubMed ID: 17419735	2007
Desmoteplase-mediated plasminogen activation and clot lysis are inhibited by the lysine analogue tranexamic acid. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis\| PubMed ID: 18469556	2008
Tissue-type plasminogen activator requires a co-receptor to enhance NMDA receptor function. Journal of neurochemistry\| PubMed ID: 18796005	2008
A nonfibrin macromolecular cofactor for tPA-mediated plasmin generation following cellular injury. Blood\| PubMed ID: 19584397	2009
Reduced phosphoinositide 3-kinase (p110alpha) activation increases the susceptibility to atrial fibrillation. The American journal of pathology\| PubMed ID: 19679877	2009
The plasminogen activator inhibitor 2 transcript is destabilized via a multi-component 3' UTR localized adenylate and uridylate-rich instability element in an analogous manner to cytokines a... The FEBS journal\| PubMed ID: 20392207	2010
Thrombin-induced activation of astrocytes in mixed rat hippocampal cultures is inhibited by soluble thrombomodulin. Brain research\| PubMed ID: 21241677	2011
Novel role of platelets in mediating inflammatory responses and ventricular rupture or remodeling following myocardial infarction. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 21252067	2011
Desmoteplase: discovery, insights and opportunities for ischaemic stroke. British journal of pharmacology\| PubMed ID: 21627637	2012
Plasminogen activator inhibitor type 2: still an enigmatic serpin but a model for gene regulation. Methods in enzymology\| PubMed ID: 21683251	2011
Plasminogen activation-based thrombolysis for ischaemic stroke: the diversity of targets may demand new approaches. Current drug targets\| PubMed ID: 21707475	2011
t-PA-specific modulation of a human blood-brain barrier model involves plasmin-mediated activation of the Rho kinase pathway in astrocytes. Blood\| PubMed ID: 22262761	2012
Role of histone acetylation in the stimulatory effect of valproic acid on vascular endothelial tissue-type plasminogen activator expression. PloS one\| PubMed ID: 22363677	2012
Plasminogen activation and thrombolysis for ischemic stroke. International journal of stroke : official journal of the International Stroke Society\| PubMed ID: 22463085	2012
Tissue-type plasminogen activator regulates the neuronal uptake of glucose in the ischemic brain. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 22815500	2012
The tissue-type plasminogen activator-plasminogen activator inhibitor 1 complex promotes neurovascular injury in brain trauma: evidence from mice and humans. Brain : a journal of neurology\| PubMed ID: 22822039	2012
Tissue plasminogen activator does not alter development of acquired epilepsy. Epilepsia\| PubMed ID: 22957978	2012
Nucleocytoplasmic coagulation: an injury-induced aggregation event that disulfide crosslinks proteins and facilitates their removal by plasmin. Cell reports\| PubMed ID: 23041318	2012
Plasminogen-stimulated inflammatory cytokine production by airway smooth muscle cells is regulated by annexin A2. American journal of respiratory cell and molecular biology\| PubMed ID: 23721211	2013
Tissue-type plasminogen activator is an extracellular mediator of Purkinje cell damage and altered gait. Experimental neurology\| PubMed ID: 23939410	2013