Peter Palese

Department of Microbiology, Icahn School of Medicine at Mount Sinai

Affiliated withIcahn School of Medicine at Mount Sinai Icahn School of Medicine at Mount Sinai

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 182	2013

Other Publications

Article	Year
Effects of influenza A virus NS1 protein on protein expression: the NS1 protein enhances translation and is not required for shutoff of host protein synthesis. Journal of virology\| PubMed ID: 11773396	2002
Apical budding of a recombinant influenza A virus expressing a hemagglutinin protein with a basolateral localization signal. Journal of virology\| PubMed ID: 11884578	2002
New directions in vaccine research. The Journal of clinical investigation\| PubMed ID: 12070295	2002
Influenza vaccines: present and future. The Journal of clinical investigation\| PubMed ID: 12093881	2002
Cellular transcriptional profiling in influenza A virus-infected lung epithelial cells: the role of the nonstructural NS1 protein in the evasion of the host innate defense and its potential ... Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12149435	2002
The makings of a killer. Nature medicine\| PubMed ID: 12205448	2002
Existing antivirals are effective against influenza viruses with genes from the 1918 pandemic virus. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12368467	2002
Functional replacement of the carboxy-terminal two-thirds of the influenza A virus NS1 protein with short heterologous dimerization domains. Journal of virology\| PubMed ID: 12438621	2002
Newcastle disease virus (NDV)-based assay demonstrates interferon-antagonist activity for the NDV V protein and the Nipah virus V, W, and C proteins. Journal of virology\| PubMed ID: 12502864	2003
Activation of tumor antigen-specific cytotoxic T lymphocytes (CTLs) by human dendritic cells infected with an attenuated influenza A virus expressing a CTL epitope derived from the HER-2/neu... Journal of virology\| PubMed ID: 12805440	2003
The Ebola virus VP35 protein inhibits activation of interferon regulatory factor 3. Journal of virology\| PubMed ID: 12829834	2003
Chimeric influenza A viruses with a functional influenza B virus neuraminidase or hemagglutinin. Journal of virology\| PubMed ID: 12915528	2003
Newcastle disease virus V protein is a determinant of host range restriction. Journal of virology\| PubMed ID: 12915566	2003
Trafficking of viral genomic RNA into and out of the nucleus: influenza, Thogoto and Borna disease viruses. Virus research\| PubMed ID: 12921991	2003
Induction of protective immunity against malaria by priming-boosting immunization with recombinant cold-adapted influenza and modified vaccinia Ankara viruses expressing a CD8+-T-cell epitop... Journal of virology\| PubMed ID: 14557672	2003
Interferon antagonist proteins of influenza and vaccinia viruses are suppressors of RNA silencing. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 14745017	2004
Structure of the uncleaved human H1 hemagglutinin from the extinct 1918 influenza virus. Science (New York, N.Y.)\| PubMed ID: 14764887	2004
Pathogenicity and immunogenicity of influenza viruses with genes from the 1918 pandemic virus. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 14963236	2004
Nipah virus V and W proteins have a common STAT1-binding domain yet inhibit STAT1 activation from the cytoplasmic and nuclear compartments, respectively. Journal of virology\| PubMed ID: 15140960	2004
Induction of cellular immune responses to simian immunodeficiency virus gag by two recombinant negative-strand RNA virus vectors. Journal of virology\| PubMed ID: 15308731	2004
Influenza: old and new threats. Nature medicine\| PubMed ID: 15577936	2004
An unconventional NLS is critical for the nuclear import of the influenza A virus nucleoprotein and ribonucleoprotein. Traffic (Copenhagen, Denmark)\| PubMed ID: 15702989	2005
A novel paramyxovirus? Emerging infectious diseases\| PubMed ID: 15705331	2005
Nuclear localization of the Nipah virus W protein allows for inhibition of both virus- and toll-like receptor 3-triggered signaling pathways. Journal of virology\| PubMed ID: 15857993	2005
Stimulation of human T cells by an influenza A vector expressing a CTL epitope from the HER-2/neu protooncogene results in higher numbers of antigen-specific TCRhi cells than stimulation wit... Anticancer research\| PubMed ID: 15868901	2005
Attenuation of equine influenza viruses through truncations of the NS1 protein. Journal of virology\| PubMed ID: 15956587	2005
A single amino acid substitution in 1918 influenza virus hemagglutinin changes receptor binding specificity. Journal of virology\| PubMed ID: 16103207	2005
Influenza virus PB1-F2 protein induces cell death through mitochondrial ANT3 and VDAC1. PLoS pathogens\| PubMed ID: 16201016	2005
Characterization of the reconstructed 1918 Spanish influenza pandemic virus. Science (New York, N.Y.)\| PubMed ID: 16210530	2005
Pathogenicity of influenza viruses with genes from the 1918 pandemic virus: functional roles of alveolar macrophages and neutrophils in limiting virus replication and mortality in mice. Journal of virology\| PubMed ID: 16282492	2005
Glycan microarray analysis of the hemagglutinins from modern and pandemic influenza viruses reveals different receptor specificities. Journal of molecular biology\| PubMed ID: 16343533	2006
7a protein of severe acute respiratory syndrome coronavirus inhibits cellular protein synthesis and activates p38 mitogen-activated protein kinase. Journal of virology\| PubMed ID: 16378980	2006
What can we learn from reconstructing the extinct 1918 pandemic influenza virus? Immunity\| PubMed ID: 16473822	2006
Making better influenza virus vaccines? Emerging infectious diseases\| PubMed ID: 16494719	2006
Sequence analysis and receptor specificity of the hemagglutinin of a recent influenza H2N2 virus isolated from chicken in North America. Glycoconjugate journal\| PubMed ID: 16575526	2006
Engineered viral vaccine constructs with dual specificity: avian influenza and Newcastle disease. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16717196	2006
The guinea pig as a transmission model for human influenza viruses. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16785447	2006
Influenza A virus PB1-F2 protein contributes to viral pathogenesis in mice. Journal of virology\| PubMed ID: 16873254	2006
Genomic analysis of increased host immune and cell death responses induced by 1918 influenza virus. Nature\| PubMed ID: 17006449	2006
Severe acute respiratory syndrome coronavirus open reading frame (ORF) 3b, ORF 6, and nucleocapsid proteins function as interferon antagonists. Journal of virology\| PubMed ID: 17108024	2007
A two-amino acid change in the hemagglutinin of the 1918 influenza virus abolishes transmission. Science (New York, N.Y.)\| PubMed ID: 17272724	2007
Effective replication of human influenza viruses in mice lacking a major alpha2,6 sialyltransferase. Virus research\| PubMed ID: 17313986	2007
Live-attenuated influenza viruses as delivery vectors for Chlamydia vaccines. Immunology\| PubMed ID: 17451464	2007
Severe acute respiratory syndrome coronavirus ORF6 antagonizes STAT1 function by sequestering nuclear import factors on the rough endoplasmic reticulum/Golgi membrane. Journal of virology\| PubMed ID: 17596301	2007
Specific residues of the influenza A virus hemagglutinin viral RNA are important for efficient packaging into budding virions. Journal of virology\| PubMed ID: 17634232	2007
A single mutation in the PB1-F2 of H5N1 (HK/97) and 1918 influenza A viruses contributes to increased virulence. PLoS pathogens\| PubMed ID: 17922571	2007
Protective immunity and susceptibility to infectious diseases: lessons from the 1918 influenza pandemic. Nature immunology\| PubMed ID: 17952044	2007
Influenza virus transmission is dependent on relative humidity and temperature. PLoS pathogens\| PubMed ID: 17953482	2007
Influenza A virus PB1-F2: a small protein with a big punch. Cell host & microbe\| PubMed ID: 18005736	2007
A combination in-ovo vaccine for avian influenza virus and Newcastle disease virus. Vaccine\| PubMed ID: 18093698	2008
Highly conserved regions of influenza a virus polymerase gene segments are critical for efficient viral RNA packaging. Journal of virology\| PubMed ID: 18094182	2008
Human genes and influenza. The Journal of infectious diseases\| PubMed ID: 18171276	2008
Expression of transgenes from newcastle disease virus with a segmented genome. Journal of virology\| PubMed ID: 18199643	2008
Influenza virus transmission: basic science and implications for the use of antiviral drugs during a pandemic. Infectious disorders drug targets\| PubMed ID: 18220963	2007
Single gene reassortants identify a critical role for PB1, HA, and NA in the high virulence of the 1918 pandemic influenza virus. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18287069	2008
High temperature (30 degrees C) blocks aerosol but not contact transmission of influenza virus. Journal of virology\| PubMed ID: 18367530	2008
Combinatorial antibody libraries from survivors of the Turkish H5N1 avian influenza outbreak reveal virus neutralization strategies. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18413603	2008
A seven-segmented influenza A virus expressing the influenza C virus glycoprotein HEF. Journal of virology\| PubMed ID: 18448539	2008
Cellular proteins in influenza virus particles. PLoS pathogens\| PubMed ID: 18535660	2008
Modulation of influenza virus replication by alteration of sodium ion transport and protein kinase C activity. Antiviral research\| PubMed ID: 18585796	2008
Oseltamivir-resistant influenza A viruses are transmitted efficiently among guinea pigs by direct contact but not by aerosol. Journal of virology\| PubMed ID: 18684820	2008
Influenza B virus NS1-truncated mutants: live-attenuated vaccine approach. Journal of virology\| PubMed ID: 18768976	2008
Live attenuated influenza viruses containing NS1 truncations as vaccine candidates against H5N1 highly pathogenic avian influenza. Journal of virology\| PubMed ID: 19073731	2009
Transmission of influenza virus in a mammalian host is increased by PB2 amino acids 627K or 627E/701N. PLoS pathogens\| PubMed ID: 19119420	2009
Unsung hero Robert C. Gallo. Science (New York, N.Y.)\| PubMed ID: 19131607	2009
Blocking interhost transmission of influenza virus by vaccination in the guinea pig model. Journal of virology\| PubMed ID: 19153237	2009
Enhancement of oncolytic properties of recombinant newcastle disease virus through antagonism of cellular innate immune responses. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 19209145	2009
Nipah virus edits its P gene at high frequency to express the V and W proteins. Journal of virology\| PubMed ID: 19211754	2009
The biology of influenza viruses. Vaccine\| PubMed ID: 19230160	2008
Universal epitopes of influenza virus hemagglutinins? Nature structural & molecular biology\| PubMed ID: 19234464	2009
Transmission of influenza virus via aerosols and fomites in the guinea pig model. The Journal of infectious diseases\| PubMed ID: 19434931	2009
Preparation of genetically engineered A/H5N1 and A/H7N1 pandemic vaccine viruses by reverse genetics in a mixture of Vero and chicken embryo cells. Influenza and other respiratory viruses\| PubMed ID: 19453414	2007
Alpha-C-galactosylceramide as an adjuvant for a live attenuated influenza virus vaccine. Vaccine\| PubMed ID: 19464560	2009
Unraveling the mystery of swine influenza virus. Cell\| PubMed ID: 19524497	2009
Recombinant vectors as influenza vaccines. Current topics in microbiology and immunology\| PubMed ID: 19768410	2009
Rewiring the RNAs of influenza virus to prevent reassortment. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19805230	2009
Transmission of pandemic H1N1 influenza virus and impact of prior exposure to seasonal strains or interferon treatment. Journal of virology\| PubMed ID: 19828604	2010
Detection of free peritoneal cancer cells in gastric cancer using cancer-specific Newcastle disease virus. Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract\| PubMed ID: 19902312	2010
Hemagglutinin-pseudotyped green fluorescent protein-expressing influenza viruses for the detection of influenza virus neutralizing antibodies. Journal of virology\| PubMed ID: 19939917	2010
Transmission of influenza virus in temperate zones is predominantly by aerosol, in the tropics by contact: a hypothesis. PLoS currents\| PubMed ID: 20025197	2009
Human host factors required for influenza virus replication. Nature\| PubMed ID: 20027183	2010
Protection of mice against lethal challenge with 2009 H1N1 influenza A virus by 1918-like and classical swine H1N1 based vaccines. PLoS pathogens\| PubMed ID: 20126449	2010
PB1-F2 expression by the 2009 pandemic H1N1 influenza virus has minimal impact on virulence in animal models. Journal of virology\| PubMed ID: 20181699	2010
Broadly protective monoclonal antibodies against H3 influenza viruses following sequential immunization with different hemagglutinins. PLoS pathogens\| PubMed ID: 20195520	2010
A nine-segment influenza a virus carrying subtype H1 and H3 hemagglutinins. Journal of virology\| PubMed ID: 20519387	2010
Protection from the 2009 H1N1 pandemic influenza by an antibody from combinatorial survivor-based libraries. PLoS pathogens\| PubMed ID: 20628565	2010
Influenza virus vaccine based on the conserved hemagglutinin stalk domain. mBio\| PubMed ID: 20689752	2010
Oseltamivir-resistant variants of the 2009 pandemic H1N1 influenza A virus are not attenuated in the guinea pig and ferret transmission models. Journal of virology\| PubMed ID: 20739532	2010
Vaccination with a synthetic peptide from the influenza virus hemagglutinin provides protection against distinct viral subtypes. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 20956293	2010
Pandemic 2009 H1N1 vaccine protects against 1918 Spanish influenza virus. Nature communications\| PubMed ID: 20975689	2010
A single N66S mutation in the PB1-F2 protein of influenza A virus increases virulence by inhibiting the early interferon response in vivo. Journal of virology\| PubMed ID: 21084483	2011
Transmission of a 2009 pandemic influenza virus shows a sensitivity to temperature and humidity similar to that of an H3N2 seasonal strain. Journal of virology\| PubMed ID: 21084485	2011
Newcastle disease virus expressing a dendritic cell-targeted HIV gag protein induces a potent gag-specific immune response in mice. Journal of virology\| PubMed ID: 21159873	2011
Budding capability of the influenza virus neuraminidase can be modulated by tetherin. Journal of virology\| PubMed ID: 21209114	2011
Broad-spectrum antiviral that interferes with de novo pyrimidine biosynthesis. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 21436031	2011
Oncolytic specificity of Newcastle disease virus is mediated by selectivity for apoptosis-resistant cells. Journal of virology\| PubMed ID: 21471241	2011
A reassortment-incompetent live attenuated influenza virus vaccine for protection against pandemic virus strains. Journal of virology\| PubMed ID: 21543486	2011
The influenza virus protein PB1-F2 inhibits the induction of type I interferon at the level of the MAVS adaptor protein. PLoS pathogens\| PubMed ID: 21695240	2011
Biochemistry. Catching a moving target. Science (New York, N.Y.)\| PubMed ID: 21836007	2011
Why do influenza virus subtypes die out? A hypothesis. mBio\| PubMed ID: 21878571	2011
The M segment of the 2009 new pandemic H1N1 influenza virus is critical for its high transmission efficiency in the guinea pig model. Journal of virology\| PubMed ID: 21880744	2011
The DBA.2 mouse is susceptible to disease following infection with a broad, but limited, range of influenza A and B viruses. Journal of virology\| PubMed ID: 21917963	2011
Therapeutic effects of a fusogenic newcastle disease virus in treating head and neck cancer. Head & neck\| PubMed ID: 21928411	2011
The influenza A virus protein PB1-F2: killing two birds with one stone? Virulence\| PubMed ID: 21971186	2011
Don't censor life-saving science. Nature\| PubMed ID: 22237069	2012
Pause on Avian Flu Transmission Research. Science (New York, N.Y.)\| PubMed ID: 22267586	2012
Pause on avian flu transmission research. Science (New York, N.Y.)\| PubMed ID: 22282787	2012
Transmission of influenza B viruses in the guinea pig. Journal of virology\| PubMed ID: 22301149	2012
H5N1 influenza viruses: facts, not fear. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 22308474	2012
Hemagglutinin stalk antibodies elicited by the 2009 pandemic influenza virus as a mechanism for the extinction of seasonal H1N1 viruses. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 22308500	2012
Efficient transmission of pandemic H1N1 influenza viruses with high-level oseltamivir resistance. Journal of virology\| PubMed ID: 22345446	2012
Seroevidence for H5N1 influenza infections in humans: meta-analysis. Science (New York, N.Y.)\| PubMed ID: 22362880	2012
Oncolytic Newcastle disease virus for cancer therapy: old challenges and new directions. Future microbiology\| PubMed ID: 22393889	2012
Influenza viruses expressing chimeric hemagglutinins: globular head and stalk domains derived from different subtypes. Journal of virology\| PubMed ID: 22398287	2012
Attenuated influenza virus construct with enhanced hemagglutinin protein expression. Journal of virology\| PubMed ID: 22398291	2012
A pan-H1 anti-hemagglutinin monoclonal antibody with potent broad-spectrum efficacy in vivo. Journal of virology\| PubMed ID: 22491456	2012
The influenza A virus PB2, PA, NP, and M segments play a pivotal role during genome packaging. Journal of virology\| PubMed ID: 22532680	2012
One influenza virus particle packages eight unique viral RNAs as shown by FISH analysis. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 22547828	2012
A novel small molecule inhibitor of influenza A viruses that targets polymerase function and indirectly induces interferon. PLoS pathogens\| PubMed ID: 22577360	2012
Influenza virus protein PB1-F2 inhibits the induction of type I interferon by binding to MAVS and decreasing mitochondrial membrane potential. Journal of virology\| PubMed ID: 22674996	2012
Influenza virus infection in guinea pigs raised as livestock, Ecuador. Emerging infectious diseases\| PubMed ID: 22710350	2012
NS1-truncated live attenuated virus vaccine provides robust protection to aged mice from viral challenge. Journal of virology\| PubMed ID: 22787224	2012
Hemagglutinin Stalk-Reactive Antibodies Are Boosted following Sequential Infection with Seasonal and Pandemic H1N1 Influenza Virus in Mice. Journal of virology\| PubMed ID: 22787225	2012
A majority of infectious Newcastle disease virus particles contain a single genome, while a minority contain multiple genomes. Journal of virology\| PubMed ID: 22787227	2012
A carboxy-terminal trimerization domain stabilizes conformational epitopes on the stalk domain of soluble recombinant hemagglutinin substrates. PloS one\| PubMed ID: 22928001	2012
Cross-neutralization of influenza A viruses mediated by a single antibody loop. Nature\| PubMed ID: 22982990	2012
1976 and 2009 H1N1 influenza virus vaccines boost anti-hemagglutinin stalk antibodies in humans. The Journal of infectious diseases\| PubMed ID: 23087428	2013
Identification of small molecules with type I interferon inducing properties by high-throughput screening. PloS one\| PubMed ID: 23145065	2012
Toward a universal influenza virus vaccine: prospects and challenges. Annual review of medicine\| PubMed ID: 23327522	2013
Transmission studies resume for avian flu. Science (New York, N.Y.)\| PubMed ID: 23345603	2013
H3N2 influenza virus infection induces broadly reactive hemagglutinin stalk antibodies in humans and mice. Journal of virology\| PubMed ID: 23408625	2013
Serum- and glucocorticoid-regulated kinase 1 is required for nuclear export of the ribonucleoprotein of influenza A virus. Journal of virology\| PubMed ID: 23487453	2013
Chimeric hemagglutinin influenza virus vaccine constructs elicit broadly protective stalk-specific antibodies. Journal of virology\| PubMed ID: 23576508	2013
Colocalization of Different Influenza Viral RNA Segments in the Cytoplasm before Viral Budding as Shown by Single-molecule Sensitivity FISH Analysis. PLoS pathogens\| PubMed ID: 23671419	2013
Recombinant IgA is sufficient to prevent influenza virus transmission in guinea pigs. Journal of virology\| PubMed ID: 23698296	2013
Induction of cross-reactive antibodies to novel H7N9 influenza virus by recombinant Newcastle disease virus expressing a North American lineage H7 subtype hemagglutinin. Journal of virology\| PubMed ID: 23698299	2013
In vivo bioluminescent imaging of influenza a virus infection and characterization of novel cross-protective monoclonal antibodies. Journal of virology\| PubMed ID: 23698304	2013
A small molecule multi-kinase inhibitor reduces influenza A virus replication by restricting viral RNA synthesis. Antiviral research\| PubMed ID: 23891991	2013
Neutralizing antibodies against previously encountered influenza virus strains increase over time: a longitudinal analysis. Science translational medicine\| PubMed ID: 23946196	2013
Influenza virus hemagglutinin stalk-based antibodies and vaccines. Current opinion in virology\| PubMed ID: 23978327	2013
Guiding the immune response against influenza virus hemagglutinin toward the conserved stalk domain by hyper-glycosylation of the globular head domain. Journal of virology\| PubMed ID: 24155380	2013