Gerd Kempermann

Center for Regenerative Therapies Dresden, Technische Universität Dresden

Affiliated withTechnische Universität Dresden German Center for Neurodegenerative Diseases (DZNE) Dresden

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 154	2014

Other Publications

Article	Year
Why new neurons? Possible functions for adult hippocampal neurogenesis. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 11826092	2002
Genetic influence on phenotypic differentiation in adult hippocampal neurogenesis. Brain research. Developmental brain research\| PubMed ID: 11947932	2002
Regulation of adult hippocampal neurogenesis - implications for novel theories of major depression. Bipolar disorders\| PubMed ID: 12047492	2002
Neuroplasticity in old age: sustained fivefold induction of hippocampal neurogenesis by long-term environmental enrichment. Annals of neurology\| PubMed ID: 12210782	2002
Early determination and long-term persistence of adult-generated new neurons in the hippocampus of mice. Development (Cambridge, England)\| PubMed ID: 12466205	2003
Enriched environment and physical activity stimulate hippocampal but not olfactory bulb neurogenesis. The European journal of neuroscience\| PubMed ID: 12786970	2003
Subpopulation of nestin-expressing progenitor cells in the adult murine hippocampus shows electrophysiological and morphological characteristics of astrocytes. Molecular and cellular neurosciences\| PubMed ID: 12837622	2003
Regional effects of wheel running and environmental enrichment on cell genesis and microglia proliferation in the adult murine neocortex. Cerebral cortex (New York, N.Y. : 1991)\| PubMed ID: 12853371	2003
Depressed new neurons--adult hippocampal neurogenesis and a cellular plasticity hypothesis of major depression. Biological psychiatry\| PubMed ID: 12946878	2003
Subpopulations of proliferating cells of the adult hippocampus respond differently to physiologic neurogenic stimuli. The Journal of comparative neurology\| PubMed ID: 14624480	2003
The nature and identification of quantitative trait loci: a community's view. Nature reviews. Genetics\| PubMed ID: 14634638	2003
Adult-born hippocampal neurons mature into activity-dependent responsiveness. The European journal of neuroscience\| PubMed ID: 14656319	2003
Neuroscience. Microglia: the enemy within? Science (New York, N.Y.)\| PubMed ID: 14657479	2003
Transient calretinin expression defines early postmitotic step of neuronal differentiation in adult hippocampal neurogenesis of mice. Molecular and cellular neurosciences\| PubMed ID: 14664811	2003
Differential regulation of gliogenesis in the context of adult hippocampal neurogenesis in mice. Glia\| PubMed ID: 14999812	2004
Adult hippocampal neurogenesis and voluntary running activity: circadian and dose-dependent effects. Journal of neuroscience research\| PubMed ID: 15048919	2004
Functional significance of adult neurogenesis. Current opinion in neurobiology\| PubMed ID: 15082323	2004
Milestones of neuronal development in the adult hippocampus. Trends in neurosciences\| PubMed ID: 15271491	2004
The Collaborative Cross, a community resource for the genetic analysis of complex traits. Nature genetics\| PubMed ID: 15514660	2004
Age-dependent expression of glucocorticoid- and mineralocorticoid receptors on neural precursor cell populations in the adult murine hippocampus. Aging cell\| PubMed ID: 15569353	2004
Glioblastoma-induced attraction of endogenous neural precursor cells is associated with improved survival. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 15758174	2005
A subpopulation of precursor cells in the mouse dentate gyrus receives synaptic GABAergic input. Molecular and cellular neurosciences\| PubMed ID: 15911343	2005
Adult neurogenesis and repair of the adult CNS with neural progenitors, precursors, and stem cells. Progress in neurobiology\| PubMed ID: 15913880	2005
Nestin-expressing cells divide and adopt a complex electrophysiologic phenotype after transient brain ischemia. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 15959463	2005
Proliferative response of distinct hippocampal progenitor cell populations after cortical infarcts in the adult brain. Neurobiology of disease\| PubMed ID: 16137890	2006
Seizures induce proliferation and dispersion of doublecortin-positive hippocampal progenitor cells. Experimental neurology\| PubMed ID: 16168988	2005
Physical exercise prevents age-related decline in precursor cell activity in the mouse dentate gyrus. Neurobiology of aging\| PubMed ID: 16271278	2006
New neurons in the adult mammalian brain: synaptogenesis and functional integration. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 16280573	2005
Enriched environment induces cellular plasticity in the adult substantia nigra and improves motor behavior function in the 6-OHDA rat model of Parkinson's disease. Experimental neurology\| PubMed ID: 16360152	2006
Natural variation and genetic covariance in adult hippocampal neurogenesis. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16407118	2006
A functional hypothesis for adult hippocampal neurogenesis: avoidance of catastrophic interference in the dentate gyrus. Hippocampus\| PubMed ID: 16435309	2006
Running in pregnancy transiently increases postnatal hippocampal neurogenesis in the offspring. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16537457	2006
Temporal and spatial dynamics of brain structure changes during extensive learning. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 16763039	2006
Cognitive and physical activity differently modulate disease progression in the amyloid precursor protein (APP)-23 model of Alzheimer's disease. Biological psychiatry\| PubMed ID: 16806094	2006
Role of endogenous neural stem cells in neurological disease and brain repair. Advances in experimental medicine and biology\| PubMed ID: 16955712	2006
Type-2 cells as link between glial and neuronal lineage in adult hippocampal neurogenesis. Glia\| PubMed ID: 16958090	2006
Variability of doublecortin-associated dendrite maturation in adult hippocampal neurogenesis is independent of the regulation of precursor cell proliferation. BMC neuroscience\| PubMed ID: 17105671	2006
Two genetic rat models of arterial hypertension show different mechanisms by which adult hippocampal neurogenesis is increased. Developmental neuroscience\| PubMed ID: 17148955	2007
They are not too excited: the possible role of adult-born neurons in epilepsy. Neuron\| PubMed ID: 17178397	2006
Adult hippocampal neurogenesis and aging. European archives of psychiatry and clinical neuroscience\| PubMed ID: 17401726	2007
Enriched monolayer precursor cell cultures from micro-dissected adult mouse dentate gyrus yield functional granule cell-like neurons. PloS one\| PubMed ID: 17460755	2007
Adult neurogenesis and neurodegenerative disease. Regenerative medicine\| PubMed ID: 17465817	2006
Selective targeting of adenoviral vectors to neural precursor cells in the hippocampus of adult mice: new prospects for in situ gene therapy. Stem cells (Dayton, Ohio)\| PubMed ID: 17641242	2007
Local origin and activity-dependent generation of nestin-expressing protoplasmic astrocytes in CA1. Brain structure & function\| PubMed ID: 17717696	2007
Neurogenesis in the adult hippocampus. Cell and tissue research\| PubMed ID: 17938969	2008
Physical activity and the regulation of neurogenesis in the adult and aging brain. Neuromolecular medicine\| PubMed ID: 18286387	2008
The neurogenic reserve hypothesis: what is adult hippocampal neurogenesis good for? Trends in neurosciences\| PubMed ID: 18329110	2008
Sortilin-related receptor with A-type repeats (SORLA) affects the amyloid precursor protein-dependent stimulation of ERK signaling and adult neurogenesis. The Journal of biological chemistry\| PubMed ID: 18362153	2008
The contribution of failing adult hippocampal neurogenesis to psychiatric disorders. Current opinion in psychiatry\| PubMed ID: 18382230	2008
Intermediate progenitors in adult hippocampal neurogenesis: Tbr2 expression and coordinate regulation of neuronal output. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 18385329	2008
Mild brain ischemia induces unique physiological properties in striatal astrocytes. Glia\| PubMed ID: 18442086	2008
Folate deficiency induces neurodegeneration and brain dysfunction in mice lacking uracil DNA glycosylase. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 18614692	2008
The antitumorigenic response of neural precursors depends on subventricular proliferation and age. Stem cells (Dayton, Ohio)\| PubMed ID: 18757298	2008
Cdk5 regulates accurate maturation of newborn granule cells in the adult hippocampus. PLoS biology\| PubMed ID: 18998770	2008
NMDA and benzodiazepine receptors have synergistic and antagonistic effects on precursor cells in adult hippocampal neurogenesis. The European journal of neuroscience\| PubMed ID: 19200231	2009
Age effects on the regulation of adult hippocampal neurogenesis by physical activity and environmental enrichment in the APP23 mouse model of Alzheimer disease. Hippocampus\| PubMed ID: 19219917	2009
CD4-positive T lymphocytes provide a neuroimmunological link in the control of adult hippocampal neurogenesis. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 19299695	2009
Melatonin modulates cell survival of new neurons in the hippocampus of adult mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology\| PubMed ID: 19421166	2009
Adult-generated hippocampal neurons allow the flexible use of spatially precise learning strategies. PloS one\| PubMed ID: 19421325	2009
Adaptive peripheral immune response increases proliferation of neural precursor cells in the adult hippocampus. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 19433626	2009
Tis21 expression marks not only populations of neurogenic precursor cells but also new postmitotic neurons in adult hippocampal neurogenesis. Cerebral cortex (New York, N.Y. : 1991)\| PubMed ID: 19482889	2010
Murine features of neurogenesis in the human hippocampus across the lifespan from 0 to 100 years. PloS one\| PubMed ID: 20126454	2010
Quiescent and active hippocampal neural stem cells with distinct morphologies respond selectively to physiological and pathological stimuli and aging. Cell stem cell\| PubMed ID: 20452319	2010
LRP2 in ependymal cells regulates BMP signaling in the adult neurogenic niche. Journal of cell science\| PubMed ID: 20460439	2010
Cannabinoid receptor CB1 mediates baseline and activity-induced survival of new neurons in adult hippocampal neurogenesis. Cell communication and signaling : CCS\| PubMed ID: 20565726	2010
Synaptic Network Activity Induces Neuronal Differentiation of Adult Hippocampal Precursor Cells through BDNF Signaling. Frontiers in neuroscience\| PubMed ID: 20582276	2009
Additive effects of physical exercise and environmental enrichment on adult hippocampal neurogenesis in mice. Frontiers in neuroscience\| PubMed ID: 20582277	2009
Genetics of the hippocampal transcriptome in mouse: a systematic survey and online neurogenomics resource. Frontiers in neuroscience\| PubMed ID: 20582282	2009
Commentary: Genetic news between ventricle and nose (Commentary on Poon et al.). The European journal of neuroscience\| PubMed ID: 20718852	2010
Oppositional effects of serotonin receptors 5-HT1a, 2, and 2c in the regulation of adult hippocampal neurogenesis. Frontiers in molecular neuroscience\| PubMed ID: 20721314	2010
Chronic treatment with melatonin stimulates dendrite maturation and complexity in adult hippocampal neurogenesis of mice. Journal of pineal research\| PubMed ID: 20880317	2011
Physical exercise increases Notch activity, proliferation and cell cycle exit of type-3 progenitor cells in adult hippocampal neurogenesis. The European journal of neuroscience\| PubMed ID: 20950279	2010
Physical exercise increases adult neurogenesis and telomerase activity, and improves behavioral deficits in a mouse model of schizophrenia. Brain, behavior, and immunity\| PubMed ID: 20970493	2011
Integrative analysis of low- and high-resolution eQTL. PloS one\| PubMed ID: 21085707	2010
Why and how physical activity promotes experience-induced brain plasticity. Frontiers in neuroscience\| PubMed ID: 21151782	2010
The role of additive neurogenesis and synaptic plasticity in a hippocampal memory model with grid-cell like input. PLoS computational biology\| PubMed ID: 21298080	2011
Seven principles in the regulation of adult neurogenesis. The European journal of neuroscience\| PubMed ID: 21395844	2011
Enriched environment and physical activity reduce microglia and influence the fate of NG2 cells in the amygdala of adult mice. Cell and tissue research\| PubMed ID: 21688212	2011
The pessimist's and optimist's views of adult neurogenesis. Cell\| PubMed ID: 21703445	2011
A protocol for isolation and enriched monolayer cultivation of neural precursor cells from mouse dentate gyrus. Frontiers in neuroscience\| PubMed ID: 21811434	2011
Adult Hippocampal Neurogenesis and Plasticity in the Infrapyramidal Bundle of the Mossy Fiber Projection: II. Genetic Covariation and Identification of Nos1 as Linking Candidate Gene. Frontiers in neuroscience\| PubMed ID: 21960957	2011
Adult hippocampal neurogenesis and plasticity in the infrapyramidal bundle of the mossy fiber projection: I. Co-regulation by activity. Frontiers in neuroscience\| PubMed ID: 21991243	2011
Properties of doublecortin-(DCX)-expressing cells in the piriform cortex compared to the neurogenic dentate gyrus of adult mice. PloS one\| PubMed ID: 22022443	2011
Glial cells in adult neurogenesis. Glia\| PubMed ID: 22076934	2012
Neuroscience. Youth culture in the adult brain. Science (New York, N.Y.)\| PubMed ID: 22403375	2012
New neurons for 'survival of the fittest'. Nature reviews. Neuroscience\| PubMed ID: 22948073	2012
The mammalian adult neurogenesis gene ontology (MANGO) provides a structural framework for published information on genes regulating adult hippocampal neurogenesis. PloS one\| PubMed ID: 23139788	2012
Prominin-1 allows prospective isolation of neural stem cells from the adult murine hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 23407958	2013
The α crystallin domain of small heat shock protein b8 (Hspb8) acts as survival and differentiation factor in adult hippocampal neurogenesis. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 23536091	2013
An old test for new neurons: refining the Morris water maze to study the functional relevance of adult hippocampal neurogenesis. Frontiers in neuroscience\| PubMed ID: 23653589	2013
Serotonin is required for exercise-induced adult hippocampal neurogenesis. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 23658167	2013
Emergence of individuality in genetically identical mice. Science (New York, N.Y.)\| PubMed ID: 23661762	2013
Neuroscience. What the bomb said about the brain. Science (New York, N.Y.)\| PubMed ID: 23744936	2013
Is silence golden? Effects of auditory stimuli and their absence on adult hippocampal neurogenesis. Brain structure & function\| PubMed ID: 24292324	2013
Delayed and Transient Increase of Adult Hippocampal Neurogenesis by Physical Exercise in DBA/2 Mice. PloS one\| PubMed ID: 24376750	2013