David S. Warner

Multidisciplinary Neuroprotection Laboratories, Duke University

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 33	2014

Other Publications

Article	Year
Ambulatory discharge after long-acting peripheral nerve blockade: 2382 blocks with ropivacaine. Anesthesia and analgesia\| PubMed ID: 11772802	2002
Peripheral nerve blockade with long-acting local anesthetics: a survey of the Society for Ambulatory Anesthesia. Anesthesia and analgesia\| PubMed ID: 11772803	2002
Apolipoprotein E affects the central nervous system response to injury and the development of cerebral edema. Annals of neurology\| PubMed ID: 11782990	2002
A randomized, double-blind comparison of ondansetron versus placebo for prevention of nausea and vomiting after infratentorial craniotomy. Journal of neurosurgical anesthesiology\| PubMed ID: 11907389	2002
Pharmacological correction of hypothermic P(50) shift does not alter outcome from focal cerebral ischemia in rats. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 11959653	2002
Differential cerebral gene expression during cardiopulmonary bypass in the rat: evidence for apoptosis? Anesthesia and analgesia\| PubMed ID: 12031994	2002
Mouse model of subarachnoid hemorrhage associated cerebral vasospasm: methodological analysis. Neurological research\| PubMed ID: 12117325	2002
Allopregnanolone attenuates N-methyl-D-aspartate-induced excitotoxicity and apoptosis in the human NT2 cell line in culture. Neuroscience letters\| PubMed ID: 12123853	2002
Brain oxygenation and energy metabolism: part I-biological function and pathophysiology. Neurosurgery\| PubMed ID: 12182767	2002
Attenuation of cerebral vasospasm after subarachnoid hemorrhage in mice overexpressing extracellular superoxide dismutase. Stroke; a journal of cerebral circulation\| PubMed ID: 12215605	2002
Effects of metalloporphyrin catalytic antioxidants in experimental brain ischemia. Free radical biology & medicine\| PubMed ID: 12361805	2002
Paravertebral somatic nerve block compared with peripheral nerve blocks for outpatient inguinal herniorrhaphy. Regional anesthesia and pain medicine\| PubMed ID: 12373694	2002
A catalytic antioxidant (AEOL 10150) attenuates expression of inflammatory genes in stroke. Free radical biology & medicine\| PubMed ID: 12374626	2002
Serum von Willebrand factor, matrix metalloproteinase-9, and vascular endothelial growth factor levels predict the onset of cerebral vasospasm after aneurysmal subarachnoid hemorrhage. Neurosurgery\| PubMed ID: 12383357	2002
Apolipoprotein E protects against NMDA excitotoxicity. Neurobiology of disease\| PubMed ID: 12460559	2002
Simvastatin increases endothelial nitric oxide synthase and ameliorates cerebral vasospasm resulting from subarachnoid hemorrhage. Stroke; a journal of cerebral circulation\| PubMed ID: 12468796	2002
A comparison of the remifentanil and fentanyl adverse effect profile in a multicenter phase IV study. Journal of clinical anesthesia\| PubMed ID: 12477583	2002
Hemodynamic effects of metalloporphyrin catalytic antioxidants: structure-activity relationships and species specificity. Free radical biology & medicine\| PubMed ID: 12488134	2002
Possible role for vascular cell proliferation in cerebral vasospasm after subarachnoid hemorrhage. Stroke; a journal of cerebral circulation\| PubMed ID: 12574555	2003
The difficulties of ambulatory interscalene and intra-articular infusions for rotator cuff surgery: a preliminary report. Canadian journal of anaesthesia = Journal canadien d'anesthésie\| PubMed ID: 12620950	2003
Catalytic Antioxidants as Novel Pharmacologic Approaches to Treatment of Ischemic Brain Injury. Drug news & perspectives\| PubMed ID: 12677251	2002
gamma-Aminobutyric acid-A receptors contribute to isoflurane neuroprotection in organotypic hippocampal cultures. Anesthesia and analgesia\| PubMed ID: 12873954	2003
Apolipoprotein E protects against oxidative stress in mixed neuronal-glial cell cultures by reducing glutamate toxicity. Neurochemistry international\| PubMed ID: 12971913	2004
APOE genotype and an ApoE-mimetic peptide modify the systemic and central nervous system inflammatory response. The Journal of biological chemistry\| PubMed ID: 14507923	2003
The neuroprotective effect of xenon administration during transient middle cerebral artery occlusion in mice. Anesthesiology\| PubMed ID: 14508320	2003
Altered perceptions after upper and lower extremity blocks: an initial investigation. Regional anesthesia and pain medicine\| PubMed ID: 14556134	2003
Severe hypotension is not essential for isoflurane neuroprotection against forebrain ischemia in mice. Anesthesiology\| PubMed ID: 14576552	2003
Pharmacologic protection from ischemic neuronal injury. Journal of neurosurgical anesthesiology\| PubMed ID: 14676578	2004
Perioperative neuroprotection: are we asking the right questions? Anesthesia and analgesia\| PubMed ID: 14980898	2004
Effects of isoflurane versus fentanyl-nitrous oxide anesthesia on long-term outcome from severe forebrain ischemia in the rat. Anesthesiology\| PubMed ID: 15114213	2004
A no-laminectomy spinal cord compression injury model in mice. Journal of neurotrauma\| PubMed ID: 15165367	2004
Mouse spinal cord compression injury is ameliorated by intrathecal cationic manganese(III) porphyrin catalytic antioxidant therapy. Neuroscience letters\| PubMed ID: 15276251	2004
Oxidants, antioxidants and the ischemic brain. The Journal of experimental biology\| PubMed ID: 15299043	2004
Intraischemic nitrous oxide alters neither neurologic nor histologic outcome: a comparison with dizocilpine. Anesthesia and analgesia\| PubMed ID: 15333428	2004
Treatment of traumatic brain injury: one size does not fit all. Anesthesia and analgesia\| PubMed ID: 15385377	2004
Changes in magnetization transfer MRI correlate with spreading depression-induced astroglial reactivity and increased protein expression in mice. AJR. American journal of roentgenology\| PubMed ID: 15547231	2004
Anesthetics provide limited but real protection against acute brain injury. Journal of neurosurgical anesthesiology\| PubMed ID: 15557838	2004
Apoptosis is not enhanced in primary mixed neuronal/glial cultures protected by isoflurane against N-methyl-D-aspartate excitotoxicity. Anesthesia and analgesia\| PubMed ID: 15562059	2004
A novel therapeutic derived from apolipoprotein E reduces brain inflammation and improves outcome after closed head injury. Experimental neurology\| PubMed ID: 15698624	2005
Analysis of the brain bioavailability of peripherally administered magnesium sulfate: A study in humans with acute brain injury undergoing prolonged induced hypermagnesemia. Critical care medicine\| PubMed ID: 15753761	2005
Intrathecal administration of a novel apoE-derived therapeutic peptide improves outcome following perinatal hypoxic-ischemic injury. Neuroscience letters\| PubMed ID: 15896489	2005
A retrospective analysis of a remifentanil/propofol general anesthetic for craniotomy before awake functional brain mapping. Anesthesia and analgesia\| PubMed ID: 16037168	2005
Simvastatin reduces vasospasm after aneurysmal subarachnoid hemorrhage: results of a pilot randomized clinical trial. Stroke; a journal of cerebral circulation\| PubMed ID: 16051891	2005
Isoflurane-induced neuronal degeneration: an evaluation in organotypic hippocampal slice cultures. Anesthesia and analgesia\| PubMed ID: 16115969	2005
Magnesium neuroprotection is limited in humans with acute brain injury. Neurocritical care\| PubMed ID: 16159086	2005
Peripheral nerve block techniques for ambulatory surgery. Anesthesia and analgesia\| PubMed ID: 16301239	2005
The effect of age on sciatic nerve block duration. Anesthesia and analgesia\| PubMed ID: 16428567	2006
Effects of a manganese (III) porphyrin catalytic antioxidant in a mouse closed head injury model. European journal of pharmacology\| PubMed ID: 16455070	2006
A comparison of hyperbaric oxygen versus hypoxic cerebral preconditioning in neonatal rats. Brain research\| PubMed ID: 16458861	2006
A novel apoE-derived therapeutic reduces vasospasm and improves outcome in a murine model of subarachnoid hemorrhage. Neurocritical care\| PubMed ID: 16498192	2006
Changing outcome from aneurysmal subarachnoid hemorrhage: another step closer. Anesthesiology\| PubMed ID: 16571953	2006
Induction of hypothermia after intraoperative hypoxic brain insult. Anesthesia and analgesia\| PubMed ID: 16790649	2006
Cardiac glycosides provide neuroprotection against ischemic stroke: discovery by a brain slice-based compound screening platform. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16793926	2006
Selective gamma-aminobutyric acid type A receptor antagonism reverses isoflurane ischemic neuroprotection. Anesthesiology\| PubMed ID: 16809998	2006
Levetiracetam is neuroprotective in murine models of closed head injury and subarachnoid hemorrhage. Neurocritical care\| PubMed ID: 16960300	2006
NMDA-induced apoptosis in mixed neuronal/glial cortical cell cultures: the effects of isoflurane and dizocilpine. Journal of neurosurgical anesthesiology\| PubMed ID: 17006121	2006
Dissociation between vasospasm and functional improvement in a murine model of subarachnoid hemorrhage. Neurosurgical focus\| PubMed ID: 17029343	2006
Isoflurane provides long-term protection against focal cerebral ischemia in the rat. Anesthesiology\| PubMed ID: 17197850	2007
Superparamagnetic iron oxide labeling and transplantation of adipose-derived stem cells in middle cerebral artery occlusion-injured mice. AJR. American journal of roentgenology\| PubMed ID: 17377054	2007
Simvastatin and atorvastatin improve behavioral outcome, reduce hippocampal degeneration, and improve cerebral blood flow after experimental traumatic brain injury. Experimental neurology\| PubMed ID: 17521631	2007
Transient global cerebral ischemia induces a massive increase in protein sumoylation. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 17565359	2008
Preclinical models of intracerebral hemorrhage: a translational perspective. Neurocritical care\| PubMed ID: 18058257	2008
Hypertonic saline for craniotomy? Anesthesiology\| PubMed ID: 18073540	2007
Statins in acute brain injury: getting the cart before the horse. Neurocritical care\| PubMed ID: 18094941	2008
Transient focal cerebral ischemia induces a dramatic activation of small ubiquitin-like modifier conjugation. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 18167501	2008
Cerebral ischemia/stroke and small ubiquitin-like modifier (SUMO) conjugation--a new target for therapeutic intervention? Journal of neurochemistry\| PubMed ID: 18410505	2008
Long-term cognitive dysfunction following experimental subarachnoid hemorrhage: new perspectives. Experimental neurology\| PubMed ID: 18625221	2008
The use of S100B as a biomarker in subarachnoid hemorrhage: clarity in its promise and limits. Critical care medicine\| PubMed ID: 18664797	2008
2008 in review: advancing medicine in anesthesiology. Anesthesiology\| PubMed ID: 19034092	2008
Filling in the blanks. Anesthesiology\| PubMed ID: 19104163	2009
Perioperative hypothermia: use and therapeutic implications. Journal of neurotrauma\| PubMed ID: 19231924	2009
Effect of lipophilicity of Mn (III) ortho N-alkylpyridyl- and diortho N, N'-diethylimidazolylporphyrins in two in-vitro models of oxygen and glucose deprivation-induced neuronal death. Free radical research\| PubMed ID: 19259881	2009
Drowning: a cry for help. Anesthesiology\| PubMed ID: 19417605	2009
Oxygen and glucose deprivation in an organotypic hippocampal slice model of the developing rat brain: the effects on N-methyl-D-aspartate subunit composition. Anesthesia and analgesia\| PubMed ID: 19535712	2009
Long-term neuroprotection from a potent redox-modulating metalloporphyrin in the rat. Free radical biology & medicine\| PubMed ID: 19631268	2009
Simvastatin treatment duration and cognitive preservation in experimental subarachnoid hemorrhage. Journal of neurosurgical anesthesiology\| PubMed ID: 19955895	2009
Metalloporphyrin antioxidants ameliorate normal tissue radiation damage in rat brain. International journal of radiation biology\| PubMed ID: 20148700	2010
Development of a simplified spinal cord ischemia model in mice. Journal of neuroscience methods\| PubMed ID: 20394775	2010
Adenosine-induced transient asystole for intracranial aneurysm surgery: a retrospective review. Journal of neurosurgical anesthesiology\| PubMed ID: 20706138	2011
Pharmacologically augmented S-nitrosylated hemoglobin improves recovery from murine subarachnoid hemorrhage. Stroke; a journal of cerebral circulation\| PubMed ID: 21193749	2011
Methoxy-derivatization of alkyl chains increases the in vivo efficacy of cationic Mn porphyrins. Synthesis, characterization, SOD-like activity, and SOD-deficient E. coli study of meta Mn(II... Dalton transactions (Cambridge, England : 2003)\| PubMed ID: 21384047	2011
Neuroprotective efficacy from a lipophilic redox-modulating Mn(III) N-Hexylpyridylporphyrin, MnTnHex-2-PyP: rodent models of ischemic stroke and subarachnoid hemorrhage. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 21652782	2011
Statins improve outcome in murine models of intracranial hemorrhage and traumatic brain injury: A translational approach. Journal of neurotrauma\| PubMed ID: 22233347	2012
A new SOD mimic, Mn(III) ortho N-butoxyethylpyridylporphyrin, combines superb potency and lipophilicity with low toxicity. Free radical biology & medicine\| PubMed ID: 22336516	2012
Lack of evidence for a remote effect of renal ischemia/reperfusion acute kidney injury on outcome from temporary focal cerebral ischemia in the rat. Journal of cardiothoracic and vascular anesthesia\| PubMed ID: 22841525	2013
Brain resuscitation in the drowning victim. Neurocritical care\| PubMed ID: 22956050	2012
Design, mechanism of action, bioavailability and therapeutic effects of mn porphyrin-based redox modulators. Medical principles and practice : international journal of the Kuwait University, Health Science Centre\| PubMed ID: 23075911	2013
Xenon neuroprotection in experimental stroke: interactions with hypothermia and intracerebral hemorrhage. Anesthesiology\| PubMed ID: 23143806	2012
Comprehensive pharmacokinetic studies and oral bioavailability of two Mn porphyrin-based SOD mimics, MnTE-2-PyP5+ and MnTnHex-2-PyP5+. Free radical biology & medicine\| PubMed ID: 23328731	2013
Protective astrogenesis from the SVZ niche after injury is controlled by Notch modulator Thbs4. Nature\| PubMed ID: 23615612	2013
Differential coordination demands in Fe versus Mn water-soluble cationic metalloporphyrins translate into remarkably different aqueous redox chemistry and biology. Inorganic chemistry\| PubMed ID: 23646875	2013
Metalloporphyrins as therapeutic catalytic oxidoreductants in central nervous system disorders. Antioxidants & redox signaling\| PubMed ID: 23706004	2014
Drowning resuscitation requires another state of mind. Resuscitation\| PubMed ID: 24036192	2013
Mr. Piano Man: reflections on the life of physician, scientist, and humanitarian, William L. Young, MD (1954-2013). Journal of neurosurgical anesthesiology\| PubMed ID: 24394583	2014
Volatile anesthetic sedation during therapeutic hypothermia after cardiac arrest in the ICU: a journey of a thousand miles begins with a single step. Critical care medicine\| PubMed ID: 24434469	2014
Anesthetic Neuroprotection: Antecedents and An Appraisal of Preclinical and Clinical Data Quality. Current pharmaceutical design\| PubMed ID: 24502575	2014
ApoE mimetic ameliorates motor deficit and tissue damage in rat spinal cord injury. Journal of neuroscience research\| PubMed ID: 24633884	2014