Graham C. Burdge

Human Development & Health Academic Unit, University of Southampton

Affiliated withUniversity of Southampton

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 71	2014

Other Publications

Article	Year
Regulation of dietary fatty acid entrapment in subcutaneous adipose tissue and skeletal muscle. Diabetes\| PubMed ID: 12196459	2002
Eicosapentaenoic and docosapentaenoic acids are the principal products of alpha-linolenic acid metabolism in young men*. The British journal of nutrition\| PubMed ID: 12323085	2002
Effect of reduced dietary protein intake on hepatic and plasma essential fatty acid concentrations in the adult female rat: effect of pregnancy and consequences for accumulation of arachidon... The British journal of nutrition\| PubMed ID: 12323087	2002
Conversion of alpha-linolenic acid to eicosapentaenoic, docosapentaenoic and docosahexaenoic acids in young women. The British journal of nutrition\| PubMed ID: 12323090	2002
UK Food Standards Agency alpha-linolenic acid workshop report. The British journal of nutrition\| PubMed ID: 12425738	2002
Effect of altered dietary n-3 fatty acid intake upon plasma lipid fatty acid composition, conversion of [13C]alpha-linolenic acid to longer-chain fatty acids and partitioning towards beta-ox... The British journal of nutrition\| PubMed ID: 12908891	2003
Effect of reduced maternal protein intake in pregnancy in the rat on the fatty acid composition of brain, liver, plasma, heart and lung phospholipids of the offspring after weaning. The British journal of nutrition\| PubMed ID: 12908895	2003
Inhibition of tumour necrosis factor-alpha and interleukin 6 production by mononuclear cells following dietary fish-oil supplementation in healthy men and response to antioxidant co-suppleme... The British journal of nutrition\| PubMed ID: 12908901	2003
Selective partitioning of dietary fatty acids into the VLDL TG pool in the early postprandial period. Journal of lipid research\| PubMed ID: 12923230	2003
Prostaglandin E2 production and T cell function after fish-oil supplementation: response to antioxidant cosupplementation. The American journal of clinical nutrition\| PubMed ID: 12936918	2003
Premenopausal advantages in postprandial lipid metabolism are lost in women with type 2 diabetes. Diabetes care\| PubMed ID: 14633809	2003
Incorporation of cis-9,trans-11 or trans-10,cis-12 conjugated linoleic acid into plasma and cellular lipids in healthy men. Journal of lipid research\| PubMed ID: 14754909	2004
Peripheral blood mononuclear cell fatty acid composition and inflammatory mediator production in adult Crohn's disease. Clinical nutrition (Edinburgh, Scotland)\| PubMed ID: 15297102	2004
Opposing effects of cis-9,trans-11 and trans-10,cis-12 conjugated linoleic acid on blood lipids in healthy humans. The American journal of clinical nutrition\| PubMed ID: 15321800	2004
The effect of dietary supplementation with linoleic acid to late gestation ewes on the fatty acid composition of maternal and fetal plasma and tissues and the synthetic capacity of the place... Biochimica et biophysica acta\| PubMed ID: 15522830	2004
Effects of cis-9,trans-11 and trans-10,cis-12 conjugated linoleic acid on immune cell function in healthy humans. The American journal of clinical nutrition\| PubMed ID: 15585778	2004
Plasma cytokine response during the postprandial period: a potential causal process in vascular disease? The British journal of nutrition\| PubMed ID: 15705218	2005
Selective changes to phosphatidylcholine and phosphatidylethanolamine molecular species in the developing fetal guinea pig liver and plasma. Reproduction, nutrition, development\| PubMed ID: 15762301	2004
Dietary protein restriction of pregnant rats induces and folic acid supplementation prevents epigenetic modification of hepatic gene expression in the offspring. The Journal of nutrition\| PubMed ID: 15930441	2005
The effects of conjugated linoleic acid on human health-related outcomes. The Proceedings of the Nutrition Society\| PubMed ID: 15960862	2005
Incorporation of cis-9, trans-11 conjugated linoleic acid and vaccenic acid (trans-11 18 : 1) into plasma and leucocyte lipids in healthy men consuming dairy products naturally enriched in t... The British journal of nutrition\| PubMed ID: 16115358	2005
Conversion of alpha-linolenic acid to longer-chain polyunsaturated fatty acids in human adults. Reproduction, nutrition, development\| PubMed ID: 16188209	2005
Docosahexaenoic acid is selectively enriched in plasma phospholipids during pregnancy in Trinidadian women--results of a pilot study. Reproduction, nutrition, development\| PubMed ID: 16438916	2006
Variation in [U-13C] alpha linolenic acid absorption, beta-oxidation and conversion to docosahexaenoic acid in the pre-term infant fed a DHA-enriched formula. Pediatric research\| PubMed ID: 16439591	2006
Effects of dairy products naturally enriched with cis-9,trans-11 conjugated linoleic acid on the blood lipid profile in healthy middle-aged men. The American journal of clinical nutrition\| PubMed ID: 16600923	2006
Polyunsaturated fatty acid concentrations in young men and women consuming their habitual diets. The British journal of nutrition\| PubMed ID: 16869996	2006
Homocysteine: a role in fetal programming? The British journal of nutrition\| PubMed ID: 16925844	2006
Lack of effect of meal fatty acid composition on postprandial lipid, glucose and insulin responses in men and women aged 50-65 years consuming their habitual diets. The British journal of nutrition\| PubMed ID: 16925854	2006
Differences in maternal protein intake in pregnant rats alone alter the docosahexaenoic acid concentration in the fetal and adult offspring. Metabolism: clinical and experimental\| PubMed ID: 16979417	2006
Dietary fatty acids make a rapid and substantial contribution to VLDL-triacylglycerol in the fed state. American journal of physiology. Endocrinology and metabolism\| PubMed ID: 17090753	2007
Dietary protein restriction of pregnant rats in the F0 generation induces altered methylation of hepatic gene promoters in the adult male offspring in the F1 and F2 generations. The British journal of nutrition\| PubMed ID: 17313703	2007
Epigenetic regulation of transcription: a mechanism for inducing variations in phenotype (fetal programming) by differences in nutrition during early life? The British journal of nutrition\| PubMed ID: 17381976	2007
Epigenetic mechanisms and the mismatch concept of the developmental origins of health and disease. Pediatric research\| PubMed ID: 17413851	2007
Induction of altered epigenetic regulation of the hepatic glucocorticoid receptor in the offspring of rats fed a protein-restricted diet during pregnancy suggests that reduced DNA methyltran... The British journal of nutrition\| PubMed ID: 17433129	2007
Tissue-specific stable isotope measurements of postprandial lipid metabolism in familial combined hyperlipidaemia. Atherosclerosis\| PubMed ID: 17466309	2008
Metabolic plasticity during mammalian development is directionally dependent on early nutritional status. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17646663	2007
The nature of the growth pattern and of the metabolic response to fasting in the rat are dependent upon the dietary protein and folic acid intakes of their pregnant dams and post-weaning fat... The British journal of nutrition\| PubMed ID: 17761015	2008
Feeding pregnant rats a protein-restricted diet persistently alters the methylation of specific cytosines in the hepatic PPAR alpha promoter of the offspring. The British journal of nutrition\| PubMed ID: 18186951	2008
Gender differences in the n-3 fatty acid content of tissues. The Proceedings of the Nutrition Society\| PubMed ID: 18234128	2008
Physical inactivity differentially alters dietary oleate and palmitate trafficking. Diabetes\| PubMed ID: 19017764	2009
Nutrition in early life, and risk of cancer and metabolic disease: alternative endings in an epigenetic tale? The British journal of nutrition\| PubMed ID: 19079817	2009
Dietary alpha-linolenic acid and health-related outcomes: a metabolic perspective. Nutrition research reviews\| PubMed ID: 19079874	2006
Acute consumption of fish oil improves postprandial VLDL profiles in healthy men aged 50-65 years. The British journal of nutrition\| PubMed ID: 19138437	2009
Folic acid supplementation during the juvenile-pubertal period in rats modifies the phenotype and epigenotype induced by prenatal nutrition. The Journal of nutrition\| PubMed ID: 19339705	2009
Antiretroviral therapy with or without protease inhibitors impairs postprandial TAG hydrolysis in HIV-infected men. The British journal of nutrition\| PubMed ID: 19480729	2009
Maternal high-fat feeding primes steatohepatitis in adult mice offspring, involving mitochondrial dysfunction and altered lipogenesis gene expression. Hepatology (Baltimore, Md.)\| PubMed ID: 19816994	2009
The polyunsaturated fatty acid composition of hepatic and plasma lipids differ by both sex and dietary fat intake in rats. The Journal of nutrition\| PubMed ID: 20007335	2010
Maternal protein restriction with or without folic acid supplementation during pregnancy alters the hepatic transcriptome in adult male rats. The British journal of nutrition\| PubMed ID: 20211039	2010
Nutrition, epigenetics, and developmental plasticity: implications for understanding human disease. Annual review of nutrition\| PubMed ID: 20415585	2010
Diet, nutrition and modulation of genomic expression in fetal origins of adult disease. World review of nutrition and dietetics\| PubMed ID: 20436253	2010
Effect of sex and dietary fat intake on the fatty acid composition of phospholipids and triacylglycerol in rat heart. Prostaglandins, leukotrienes, and essential fatty acids\| PubMed ID: 20719489	2010
Bridging the gap between epigenetics research and nutritional public health interventions. Genome medicine\| PubMed ID: 21067534	2010
Polyunsaturated fatty acid intakes and α-linolenic acid metabolism. The American journal of clinical nutrition\| PubMed ID: 21191139	2011
Developmental plasticity and developmental origins of non-communicable disease: theoretical considerations and epigenetic mechanisms. Progress in biophysics and molecular biology\| PubMed ID: 21219925	2011
Enteral feeding therapy for newly diagnosed pediatric Crohn's disease: a double-blind randomized controlled trial with two years follow-up. Inflammatory bowel diseases\| PubMed ID: 21425210	2012
Epigenetic gene promoter methylation at birth is associated with child's later adiposity. Diabetes\| PubMed ID: 21471513	2011
Diet, nutrition and modulation of genomic expression in fetal origins of adult disease. Journal of nutrigenetics and nutrigenomics\| PubMed ID: 21474951	2010
Umbilical venous-arterial plasma composition differences suggest differential incorporation of fatty acids in NEFA and cholesteryl ester pools. The British journal of nutrition\| PubMed ID: 21521544	2011
Dietary protein restriction during F0 pregnancy in rats induces transgenerational changes in the hepatic transcriptome in female offspring. PloS one\| PubMed ID: 21750721	2011
Increasing the folic acid content of maternal or post-weaning diets induces differential changes in phosphoenolpyruvate carboxykinase mRNA expression and promoter methylation in rats. The British journal of nutrition\| PubMed ID: 22136740	2012
Progressive, transgenerational changes in offspring phenotype and epigenotype following nutritional transition. PloS one\| PubMed ID: 22140567	2011
The effect of nutrition during early life on the epigenetic regulation of transcription and implications for human diseases. Journal of nutrigenetics and nutrigenomics\| PubMed ID: 22353662	2011
Vascular dysfunction induced in offspring by maternal dietary fat involves altered arterial polyunsaturated fatty acid biosynthesis. PloS one\| PubMed ID: 22509311	2012
Epigenetics: are there implications for personalised nutrition? Current opinion in clinical nutrition and metabolic care\| PubMed ID: 22878237	2012
Epigenetic mechanisms linking early nutrition to long term health. Best practice & research. Clinical endocrinology & metabolism\| PubMed ID: 22980048	2012
Folic acid supplementation in pregnancy: Are there devils in the detail? The British journal of nutrition\| PubMed ID: 23046900	2012
Maternal fat intake in rats alters 20:4n-6 and 22:6n-3 status and the epigenetic regulation of Fads2 in offspring liver. The Journal of nutritional biochemistry\| PubMed ID: 23107313	2013
Non-imprinted epigenetics in fetal and postnatal development and growth. Nestlé Nutrition Institute workshop series\| PubMed ID: 23502139	2013
Tissue-specific 5' heterogeneity of PPARα transcripts and their differential regulation by leptin. PloS one\| PubMed ID: 23825665	2013
Improving articles reporting nutritional studies of extracts in the British Journal of Nutrition and in the Journal of Nutritional Science. The British journal of nutrition\| PubMed ID: 23919933	2014
Increasing numbers of citations and higher impact factor in 2012: the British Journal of Nutrition continues to show steady improvement. The British journal of nutrition\| PubMed ID: 23953924	2013
Breast cancer and the importance of early life nutrition. Cancer treatment and research\| PubMed ID: 24114486	2014
DHA supplementation during pregnancy and DNA methylation in cord blood leukocytes. The American journal of clinical nutrition\| PubMed ID: 24259358	2013
Fatty acids and epigenetics. Current opinion in clinical nutrition and metabolic care\| PubMed ID: 24322369	2014
Site distribution at the edge of the palaeolithic world: a nutritional niche approach. PloS one\| PubMed ID: 24339935	2013
Environment-physiology, diet quality and energy balance: The influence of early life nutrition on future energy balance. Physiology & behavior\| PubMed ID: 24394988	2014
Effect of sex hormones on n-3 polyunsaturated fatty acid biosynthesis in HepG2 cells and in human primary hepatocytes. Prostaglandins, leukotrienes, and essential fatty acids\| PubMed ID: 24411721	2014
Differential Pathways to Adult Metabolic Dysfunction following Poor Nutrition at Two Critical Developmental Periods in Sheep. PloS one\| PubMed ID: 24603546	2014