Edward R. O'Brien

Libin Cardiovascular Institute of Alberta, University of Calgary

Research Area

Biography

Edward R. O'Brien has not added Biography.
If you are Edward R. O'Brien and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 6	2014

Other Publications

Article	Year
Hospitalization costs of primary stenting versus thrombolysis in acute myocardial infarction: cost analysis of the Canadian STAT Study. Circulation\| PubMed ID: 14597591	2003
Antagonism of the alpha4 integrin subunit attenuates the acute inflammatory response to stent implantation yet is insufficient to prevent late intimal formation. Journal of leukocyte biology\| PubMed ID: 15020653	2004
c-kit-immunopositive vascular progenitor cells populate human coronary in-stent restenosis but not primary atherosclerotic lesions. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 15277195	2004
Novel antiinflammatory vascular benefits of systemic and stent-based delivery of ethylisopropylamiloride. Circulation\| PubMed ID: 15505102	2004
17beta-estradiol downregulates tissue angiotensin-converting enzyme and ANG II type 1 receptor in female rats. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 15550614	2005
Modulation of estrogen signaling by the novel interaction of heat shock protein 27, a biomarker for atherosclerosis, and estrogen receptor beta: mechanistic insight into the vascular effects... Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 15662019	2005
Combined angioplasty and pharmacological intervention versus thrombolysis alone in acute myocardial infarction (CAPITAL AMI study). Journal of the American College of Cardiology\| PubMed ID: 16053952	2005
Regulation of components of the brain and cardiac renin-angiotensin systems by 17beta-estradiol after myocardial infarction in female rats. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 16455770	2006
Comparison of processing and sectioning methodologies for arteries containing metallic stents. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society\| PubMed ID: 16714423	2006
Comparison of early mortality of paramedic-diagnosed ST-segment elevation myocardial infarction with immediate transport to a designated primary percutaneous coronary intervention center to ... The American journal of cardiology\| PubMed ID: 17134623	2006
NM23-H2, an estrogen receptor beta-associated protein, shows diminished expression with progression of atherosclerosis. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 17272673	2007
The interaction and cellular localization of HSP27 and ERbeta are modulated by 17beta-estradiol and HSP27 phosphorylation. Molecular and cellular endocrinology\| PubMed ID: 17350752	2007
Discovery of NM23-H2 as an estrogen receptor beta-associated protein: role in estrogen-induced gene transcription and cell migration. The Journal of steroid biochemistry and molecular biology\| PubMed ID: 17964137	2008
A citywide protocol for primary PCI in ST-segment elevation myocardial infarction. The New England journal of medicine\| PubMed ID: 18199862	2008
Contribution of recipient-derived cells in allograft neointima formation and the response to stent implantation. PloS one\| PubMed ID: 18365026	2008
Letter by Hibbert et al regarding article, "Smooth muscle cells healing atherosclerotic plaque disruptions are of local, not blood, origin in apolipoprotein E knockout mice". Circulation\| PubMed ID: 18427139	2008
Extracellular release of the atheroprotective heat shock protein 27 is mediated by estrogen and competitively inhibits acLDL binding to scavenger receptor-A. Circulation research\| PubMed ID: 18566345	2008
Inhibition of endothelial progenitor cell glycogen synthase kinase-3beta results in attenuated neointima formation and enhanced re-endothelialization after arterial injury. Cardiovascular research\| PubMed ID: 19454488	2009
Heat shock protein 27 protects against atherogenesis via an estrogen-dependent mechanism: role of selective estrogen receptor beta modulation. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 19729610	2009
Primary percutaneous coronary angioplasty with and without eptifibatide in ST-segment elevation myocardial infarction: a safety and efficacy study of integrilin-facilitated versus primary pe... Circulation. Cardiovascular interventions\| PubMed ID: 20031736	2009
Delayed re-endothelialization with rapamycin-coated stents is rescued by the addition of a glycogen synthase kinase-3beta inhibitor. Cardiovascular research\| PubMed ID: 20167573	2010
Heat shock protein 27: clue to understanding estrogen-mediated atheroprotection? Trends in cardiovascular medicine\| PubMed ID: 20656216	2010
Cardiovascular complications of Salmonella enteritidis infection. The Canadian journal of cardiology\| PubMed ID: 20931102	2010
Pre-procedural atorvastatin mobilizes endothelial progenitor cells: clues to the salutary effects of statins on healing of stented human arteries. PloS one\| PubMed ID: 21283543	2011
Coronary stent fracture. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne\| PubMed ID: 21444617	2011
Circulating endothelial progenitor cell levels are not reduced in HIV-infected men. The Journal of infectious diseases\| PubMed ID: 22238473	2012
Percutaneous coronary intervention with or without on-site coronary artery bypass surgery: a systematic review and meta-analysis. International journal of cardiology\| PubMed ID: 22240768	2013
Infective endocarditis presenting as ST-elevation myocardial infarction: an angiographic diagnosis. The Canadian journal of cardiology\| PubMed ID: 22381910	2012
Transbrachial insertion of an intra-aortic balloon pump for high-risk percutaneous coronary intervention. Clinical research in cardiology : official journal of the German Cardiac Society\| PubMed ID: 22552835	2012
Extracellular HSP27 acts as a signaling molecule to activate NF-κB in macrophages. Cell stress & chaperones\| PubMed ID: 22851137	2013
Transradial versus transfemoral artery approach for coronary angiography and percutaneous coronary intervention in the extremely obese. JACC. Cardiovascular interventions\| PubMed ID: 22917453	2012
Reduction in mortality as a result of direct transport from the field to a receiving center for primary percutaneous coronary intervention. Journal of the American College of Cardiology\| PubMed ID: 23017532	2012
Natural history and management of aortocoronary saphenous vein graft aneurysms: a systematic review of published cases. Circulation\| PubMed ID: 23109515	2012
Bivalirudin for primary percutaneous coronary interventions: outcome assessment in the Ottawa STEMI registry. Circulation. Cardiovascular interventions\| PubMed ID: 23149331	2012
Circulating endothelial progenitor cells in HIV infection: a systematic review. Trends in cardiovascular medicine\| PubMed ID: 23395428	2013
Chronic over-expression of heat shock protein 27 attenuates atherogenesis and enhances plaque remodeling: a combined histological and mechanical assessment of aortic lesions. PloS one\| PubMed ID: 23409070	2013
Neuroimmune guidance cue Semaphorin 3E is expressed in atherosclerotic plaques and regulates macrophage retention. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 23430613	2013
Response to letter regarding article, "Bivalirudin for primary percutaneous coronary interventions: outcome assessment in the Ottawa STEMI registry". Circulation. Cardiovascular interventions\| PubMed ID: 23591426	2013
Serum heat shock protein 27 levels represent a potential therapeutic target for atherosclerosis: observations from a human cohort and treatment of female mice. Journal of the American College of Cardiology\| PubMed ID: 23764828	2013
The effect of statins on circulating endothelial progenitor cells in humans: a systematic review. Journal of cardiovascular pharmacology\| PubMed ID: 23933855	2013
Heat shock protein-27 attenuates foam cell formation and atherogenesis by down-regulating scavenger receptor-A expression via NF-κB signaling. Biochimica et biophysica acta\| PubMed ID: 23939398	2013
Heat shock protein 27 attenuates neointima formation and accelerates reendothelialization after arterial injury and stent implantation: importance of vascular endothelial growth factor up-re... FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 24142570	2014
Giant saphenous vein graft aneurysm presenting as ST-elevation myocardial infarction. Circulation journal : official journal of the Japanese Circulation Society\| PubMed ID: 24284922	2014
The evolution of coronary stents: a brief review. The Canadian journal of cardiology\| PubMed ID: 24286961	2014
Circulating endothelial progenitor cells and in-stent restenosis: friend, foe, or none of the above? The Canadian journal of cardiology\| PubMed ID: 24290519	2014
Glycogen synthase kinase-3β inhibition augments diabetic endothelial progenitor cell abundance and functionality via cathepsin B: a novel therapeutic opportunity for arterial repair. Diabetes\| PubMed ID: 24296714	2014