Gareth Thomas

Cancer Sciences Unit, University of Southampton School of Medicine

Affiliated withUniversity of Southampton School of Medicine

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 2	2014

Other Publications

Article	Year
The statistical merits of various methods of calculating transfer coefficients between environmental media--development of the ideal formula for data-sets with a log-normal distribution. Chemosphere\| PubMed ID: 11999772	2002
Polychlorinated dibenzo-p-dioxin and furan (PCDD/F) uptake by pasture. Environmental science & technology\| PubMed ID: 12075792	2002
Air-side and plant-side resistances influence the uptake of airborne PCBs by evergreen plants. Environmental science & technology\| PubMed ID: 12188344	2002
An input-output balance study for PCBs in humans. Environment international\| PubMed ID: 12222617	2002
Investigation into the importance of the stomatal pathway in the exchange of PCBs between air and plants. Environmental science & technology\| PubMed ID: 12387399	2002
Structural and functional changes in heparan sulfate proteoglycan expression associated with the myofibroblastic phenotype. The American journal of pathology\| PubMed ID: 12598330	2003
Scatter factor regulation of integrin expression and function on oral epithelial cells. Archives of dermatological research\| PubMed ID: 12750924	2003
Polybrominated diphenyl ethers (PBDEs) in grey seals during their first year of life--are they thyroid hormone endocrine disrupters? Environmental pollution (Barking, Essex : 1987)\| PubMed ID: 12860100	2003
Study of plant-air transfer of PCBs from an evergreen shrub: implications for mechanisms and modeling. Environmental science & technology\| PubMed ID: 12967103	2003
A multicenter, single-masked study of medial, neutral, and lateral patellar taping in individuals with patellofemoral pain syndrome. The Journal of orthopaedic and sports physical therapy\| PubMed ID: 12968857	2003
Occurrence of polychlorinated biphenyls and polybrominated diphenyl ethers in green mussels (Perna viridis) from Singapore, Southeast Asia. Environmental toxicology and chemistry / SETAC\| PubMed ID: 14552008	2003
Current issues and uncertainties in the measurement and modelling of air-vegetation exchange and within-plant processing of POPs. Environmental pollution (Barking, Essex : 1987)\| PubMed ID: 14667723	2004
Low dose induction of micronuclei by lindane. Carcinogenesis\| PubMed ID: 14688026	2004
Stress- and mitogen-induced phosphorylation of the synapse-associated protein SAP90/PSD-95 by activation of SAPK3/p38gamma and ERK1/ERK2. The Biochemical journal\| PubMed ID: 14741046	2004
PBDEs in the atmosphere of three locations in western Europe. Environmental science & technology\| PubMed ID: 14968853	2004
PBDEs in European background soils: levels and factors controlling their distribution. Environmental science & technology\| PubMed ID: 14968858	2004
MAPK cascade signalling and synaptic plasticity. Nature reviews. Neuroscience\| PubMed ID: 14976517	2004
Modulation of the urokinase-type plasminogen activator receptor by the beta6 integrin subunit. Biochemical and biophysical research communications\| PubMed ID: 15047152	2004
The integrin cytoplasmic-tail motif EKQKVDLSTDC is sufficient to promote tumor cell invasion mediated by matrix metalloproteinase (MMP)-2 or MMP-9. The Journal of biological chemistry\| PubMed ID: 15067014	2004
Attenuated type II TGF-beta receptor signalling in human malignant oral keratinocytes induces a less differentiated and more aggressive phenotype that is associated with metastatic dissemina... International journal of cancer. Journal international du cancer\| PubMed ID: 15069677	2004
Catabolism of newly synthesized decorin in vitro by human peritoneal mesothelial cells. Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis\| PubMed ID: 15119635	2004
Further studies on the latitudinal and temporal trends of persistent organic pollutants in Norwegian and U.K. background air. Environmental science & technology\| PubMed ID: 15180046	2004
Different levels of polybrominated diphenyl ethers (PBDEs) and chlorinated compounds in breast milk from two U.K. Regions. Environmental health perspectives\| PubMed ID: 15238282	2004
Myofibroblastic differentiation leads to hyaluronan accumulation through reduced hyaluronan turnover. The Journal of biological chemistry\| PubMed ID: 15271981	2004
New magnetic nanoparticles for biotechnology. Journal of biotechnology\| PubMed ID: 15288940	2004
Inter-individual differences in the ability of human milk-fat extracts to enhance the genotoxic potential of the procarcinogen benzo[a]pyrene in MCF-7 breast cells. Environmental science & technology\| PubMed ID: 15296313	2004
Exchange of polychlorinated biphenyls (PCBs) and polychlorinated naphthalenes (PCNs) between air and a mixed pasture sward. Environmental science & technology\| PubMed ID: 15298198	2004
A novel analytical approach for visualizing and tracking organic chemicals in plants. Environmental science & technology\| PubMed ID: 15352460	2004
Calculation of Mie derivatives. Applied optics\| PubMed ID: 15495430	2004
Absorption of decabromodiphenyl ether and other organohalogen chemicals by grey seals (Halichoerus grypus). Environmental pollution (Barking, Essex : 1987)\| PubMed ID: 15519732	2005
Real-time visualization and quantification of PAH photodegradation on and within plant leaves. Environmental science & technology\| PubMed ID: 15667104	2005
Retrieval of aerosol refractive index from extinction spectra with a damped harmonic-oscillator band model. Applied optics\| PubMed ID: 15765714	2005
Digital ischemia associated with squamous cell carcinoma of the esophagus. Digestive diseases and sciences\| PubMed ID: 15844703	2005
Time trends of atmospheric PBDEs inferred from archived U.K. herbage. Environmental science & technology\| PubMed ID: 15884332	2005
Direct observation of organic contaminant uptake, storage, and metabolism within plant roots. Environmental science & technology\| PubMed ID: 15952374	2005
Short and medium chain length chlorinated paraffins in UK human milk fat. Environment international\| PubMed ID: 15979717	2006
Spatial and temporal variability in air concentrations of short-chain (C10-C13) and medium-chain (C14-C17) chlorinated n-alkanes measured in the U.K. atmosphere. Environmental science & technology\| PubMed ID: 16047774	2005
Detailed study of factors controlling atmospheric concentrations of PCNs. Environmental science & technology\| PubMed ID: 16053070	2005
Squamous cell carcinoma arising in a residual odontogenic cyst: case report. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons\| PubMed ID: 16094597	2005
Ribosomal S6 kinase 2 interacts with and phosphorylates PDZ domain-containing proteins and regulates AMPA receptor transmission. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16217014	2005
Organohalogen chemicals in human blood from the United Kingdom. Environmental pollution (Barking, Essex : 1987)\| PubMed ID: 16236409	2006
A randomized trial of nicotine enemas for active ulcerative colitis. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association\| PubMed ID: 16271342	2005
Comment on "Early treatment with activated protein C for meningococcal septic shock: case report and literature review" by Hasin et al. Intensive care medicine\| PubMed ID: 16283165	2005
Preliminary observations of oral nicotine therapy for inflammatory bowel disease: an open-label phase I-II study of tolerance. Inflammatory bowel diseases\| PubMed ID: 16306772	2005
Mechanisms of disease: nicotine--a review of its actions in the context of gastrointestinal disease. Nature clinical practice. Gastroenterology & hepatology\| PubMed ID: 16355159	2005
Nitric oxide is a factor in the stabilization of hypoxia-inducible factor-1alpha in cancer: role of free radical formation. Cancer research\| PubMed ID: 16424008	2006
Visualizing the air-to-leaf transfer and within-leaf movement and distribution of phenanthrene: further studies utilizing two-photon excitation microscopy. Environmental science & technology\| PubMed ID: 16509336	2006
Targeted in vivo mutations of the AMPA receptor subunit GluR2 and its interacting protein PICK1 eliminate cerebellar long-term depression. Neuron\| PubMed ID: 16543133	2006
Inflammatory external root resorption following surgical treatment for intra-bony defects: a report of two cases involving Emdogain and a review of the literature. Journal of clinical periodontology\| PubMed ID: 16677335	2006
Chlorinated paraffins: a review of analysis and environmental occurrence. Environment international\| PubMed ID: 16814386	2006
Persistent organic pollutants in European background air: derivation of temporal and latitudinal trends. Journal of environmental monitoring : JEM\| PubMed ID: 16826283	2006
Cyclooxygenase-2 inhibition suppresses alphavbeta6 integrin-dependent oral squamous carcinoma invasion. Cancer research\| PubMed ID: 17108119	2006
Sex, politics, and money. Lancet\| PubMed ID: 17141686	2006
Fate of higher brominated PBDEs in lactating cows. Environmental science & technology\| PubMed ID: 17310701	2007
Prospective randomized clinical trial of the effect of needle size on pain, sample adequacy and accuracy in head and neck fine-needle aspiration cytology. Head & neck\| PubMed ID: 17405171	2007
Polychlorinated biphenyls, DDT, polybrominated diphenyl ethers, and organic pesticides in United Kingdom harbor seals (Phoca vitulina)--mixed exposures and thyroid homeostasis. Environmental toxicology and chemistry / SETAC\| PubMed ID: 17521129	2007
HS1-associated protein X-1 regulates carcinoma cell migration and invasion via clathrin-mediated endocytosis of integrin alphavbeta6. Cancer research\| PubMed ID: 17545607	2007
Pseudosubarachnoid haemorrhage on CT brain scan: an unusual presentation of diffuse hypoxic brain injury. Intensive care medicine\| PubMed ID: 17576538	2007
Inducible nitric oxide synthase: correlation with extracapsular spread and enhancement of tumor cell invasion in head and neck squamous cell carcinoma. Head & neck\| PubMed ID: 17657783	2008
GRASP-1 is a neuronal scaffold protein for the JNK signaling pathway. FEBS letters\| PubMed ID: 17761173	2007
Exposure of electronics dismantling workers to polybrominated diphenyl ethers, polychlorinated biphenyls, and organochlorine pesticides in South China. Environmental science & technology\| PubMed ID: 17874768	2007
Infrared spectral analysis of MCF-7 cells treated with serum-lipid extracts segregates predominantly brominated flame retardant-exposed subjects from those with mainly organochlorine exposur... Environmental science & technology\| PubMed ID: 17874806	2007
PAHs in background soils from Western Europe: influence of atmospheric deposition and soil organic matter. Chemosphere\| PubMed ID: 17888489	2008
Decabromodiphenyl ether (deca-BDE) commercial mixture components, and other PBDEs, in airborne particles at a UK site. Environment international\| PubMed ID: 17961649	2008
Validation of a passive atmospheric deposition sampler for polybrominated diphenyl ethers. Journal of environmental monitoring : JEM\| PubMed ID: 17968443	2007
Hyaluronan induces the selective accumulation of matrix- and cell-associated proteoglycans by mesangial cells. The American journal of pathology\| PubMed ID: 17974600	2007
Use of two-photon excitation microscopy and autofluorescence for visualizing the fate and behavior of semivolatile organic chemicals within living vegetation. Environmental toxicology and chemistry / SETAC\| PubMed ID: 18020674	2007
The 120 kDa cell-binding fragment of fibronectin up-regulates migration of alphavbeta6-expressing cells by increasing matrix metalloproteinase-2 and -9 secretion. European journal of oral sciences\| PubMed ID: 18028052	2007
Farnesoid x receptor ligands inhibit vascular smooth muscle cell inflammation and migration. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 18029909	2007
The consequences of smoking and tobacco on lung disease in developing countries: plenary lecture given during the 37th Union World Conference on Lung Health, Palais des Congrès, Paris, Franc... The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease\| PubMed ID: 18034946	2007
Rapid and bi-directional regulation of AMPA receptor phosphorylation and trafficking by JNK. The EMBO journal\| PubMed ID: 18188153	2008
Antibody-mediated blockade of integrin alpha v beta 6 inhibits tumor progression in vivo by a transforming growth factor-beta-regulated mechanism. Cancer research\| PubMed ID: 18199553	2008
Uptake and storage of PCBs by plant cuticles. Environmental science & technology\| PubMed ID: 18350882	2008
alpha vbeta 6 Integrin promotes the invasion of morphoeic basal cell carcinoma through stromal modulation. Cancer research\| PubMed ID: 18451156	2008
Engineering a single-chain Fv antibody to alpha v beta 6 integrin using the specificity-determining loop of a foot-and-mouth disease virus. Journal of molecular biology\| PubMed ID: 18656482	2008
Use of quantitative structural analysis to predict fish bioconcentration factors for pesticides. Journal of agricultural and food chemistry\| PubMed ID: 19138085	2009
Determination of protein denaturation and glass transition temperatures using high-frequency time domain reflectometry. The journal of physical chemistry. B\| PubMed ID: 19368035	2008
In vivo retargeting of adenovirus type 5 to alphavbeta6 integrin results in reduced hepatotoxicity and improved tumor uptake following systemic delivery. Journal of virology\| PubMed ID: 19369326	2009
A mass balance of tri-hexabrominated diphenyl ethers in lactating cows. Environmental science & technology\| PubMed ID: 19452923	2009
Polybrominated diphenyl ether-associated alterations in cell biochemistry as determined by attenuated total reflection Fourier-transform infrared spectroscopy: a comparison with DNA-reactive... Environmental science & technology\| PubMed ID: 19534158	2009
Exposure to persistent organic pollutants and first-year survival probability in gray seal pups. Environmental science & technology\| PubMed ID: 19746738	2009
Dual palmitoylation of NR2 subunits regulates NMDA receptor trafficking. Neuron\| PubMed ID: 19874789	2009
Regulation of lymphatic-blood vessel separation by endothelial Rac1. Development (Cambridge, England)\| PubMed ID: 19906871	2009
Endothelial-Rac1 is not required for tumor angiogenesis unless alphavbeta3-integrin is absent. PloS one\| PubMed ID: 20339539	2010
Clinicopathological parameters, recurrence, locoregional and distant metastasis in 115 T1-T2 oral squamous cell carcinoma patients. Head & neck oncology\| PubMed ID: 20406474	2010
Dual actions of lindane (γ-hexachlorocyclohexane) on calcium homeostasis and exocytosis in rat PC12 cells. Toxicology and applied pharmacology\| PubMed ID: 20600211	2010
High-resolution in vivo imaging of breast cancer by targeting the pro-invasive integrin alphavbeta6. The Journal of pathology\| PubMed ID: 20629113	2010
A comparison of primary oesophageal squamous epithelial cells with HET-1A in organotypic culture. Biology of the cell / under the auspices of the European Cell Biology Organization\| PubMed ID: 20843300	2010
GRIP1 and 2 regulate activity-dependent AMPA receptor recycling via exocyst complex interactions. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 20956289	2010
Betel-derived alkaloid up-regulates keratinocyte alphavbeta6 integrin expression and promotes oral submucous fibrosis. The Journal of pathology\| PubMed ID: 21171082	2011
Stromal features are predictive of disease mortality in oral cancer patients. The Journal of pathology\| PubMed ID: 21294121	2011
Gain-of-function glutamate receptor interacting protein 1 variants alter GluA2 recycling and surface distribution in patients with autism. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 21383172	2011
Cell migration and invasion assays. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 21516419	2011
GLI1 confers profound phenotypic changes upon LNCaP prostate cancer cells that include the acquisition of a hormone independent state. PloS one\| PubMed ID: 21633508	2011
Measuring invasion in an organotypic model. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 21748679	2011
A rare case of iron deficiency. European journal of gastroenterology & hepatology\| PubMed ID: 22008628	2012
SynaptomeDB: an ontology-based knowledgebase for synaptic genes. Bioinformatics (Oxford, England)\| PubMed ID: 22285564	2012
Palmitoylation by DHHC5/8 targets GRIP1 to dendritic endosomes to regulate AMPA-R trafficking. Neuron\| PubMed ID: 22325201	2012
Cardiorespiratory safety evaluation in non-human primates. Journal of pharmacological and toxicological methods\| PubMed ID: 22521338	2012
Combined fiber modifications both to target α(v)β(6) and detarget the coxsackievirus-adenovirus receptor improve virus toxicity profiles in vivo but fail to improve antitumoral efficacy rela... Human gene therapy\| PubMed ID: 22708837	2012
A rare complication with a single dose of alendronate. BMJ case reports\| PubMed ID: 22778283	2010
Palmitoylation-dependent regulation of glutamate receptors and their PDZ domain-containing partners. Biochemical Society transactions\| PubMed ID: 23356261	2013
Progression of genotype-specific oral cancer leads to senescence of cancer-associated fibroblasts and is mediated by oxidative stress and TGF-β. Carcinogenesis\| PubMed ID: 23358854	2013
Tumor-stromal interactions in pancreatic cancer. Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]\| PubMed ID: 23395563	2013
Smarter neuronal signaling complexes from existing components: how regulatory modifications were acquired during animal evolution: evolution of palmitoylation-dependent regulation of AMPA-ty... BioEssays : news and reviews in molecular, cellular and developmental biology\| PubMed ID: 23943381	2013
miR-153 supports colorectal cancer progression via pleiotropic effects that enhance invasion and chemotherapeutic resistance. Cancer research\| PubMed ID: 23950211	2013
Generation and characterization of a diabody targeting the αvβ6 integrin. PloS one\| PubMed ID: 24023846	2013
DHHC8-dependent PICK1 palmitoylation is required for induction of cerebellar long-term synaptic depression. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 24068808	2013
Altered microenvironment promotes progression of preinvasive breast cancer: myoepithelial expression of αvβ6 integrin in DCIS identifies high-risk patients and predicts recurrence. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 24150233	2014
The role of tumour stroma in colorectal cancer invasion and metastasis. Cancers\| PubMed ID: 24212801	2011
In vitro effect of bisphosphonates on oral keratinocytes and fibroblasts. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons\| PubMed ID: 24342576	2014
Identification of ZDHHC14 as a novel human tumour suppressor gene. The Journal of pathology\| PubMed ID: 24407904	2014
Suppression of hedgehog signalling promotes pro-tumourigenic integrin expression and function. The Journal of pathology\| PubMed ID: 24573955	2014
The immune response in HPV(+) oropharyngeal cancer. Oncoimmunology\| PubMed ID: 24575385	2014