Carl W. White

Pediatric Airway Research Center, University of Colorado

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 25	2014

Other Publications

Article	Year
Silibinin attenuates sulfur mustard analog-induced skin injury by targeting multiple pathways connecting oxidative stress and inflammation. PloS one\| PubMed ID: 23029417	2012
Oxidized phospholipids derived from ozone-treated lung surfactant extract reduce macrophage and epithelial cell viability. Chemical research in toxicology\| PubMed ID: 12118999	2002
Redox systems of the cell: possible links and implications. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12122214	2002
Elevated expression of hexokinase II protects human lung epithelial-like A549 cells against oxidative injury. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 12169577	2002
Extracellular ATP is an autocrine/paracrine regulator of hypoxia-induced adventitial fibroblast growth. Signaling through extracellular signal-regulated kinase-1/2 and the Egr-1 transcriptio... The Journal of biological chemistry\| PubMed ID: 12244041	2002
Hypoxia protects human lung microvascular endothelial and epithelial-like cells against oxygen toxicity: role of phosphatidylinositol 3-kinase. American journal of respiratory cell and molecular biology\| PubMed ID: 12540485	2003
Composition of coronary atherosclerotic plaques in patients with acute myocardial infarction and stable angina pectoris determined by contrast-enhanced multislice computed tomography. The American journal of cardiology\| PubMed ID: 12633805	2003
Thioredoxin liquefies and decreases the viscoelasticity of cystic fibrosis sputum. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 14695120	2004
Hyperoxia-induced DNA damage causes decreased DNA methylation in human lung epithelial-like A549 cells. Antioxidants & redox signaling\| PubMed ID: 14713344	2004
Potential role for antiangiogenic proteins in the evolution of bronchopulmonary dysplasia. Antioxidants & redox signaling\| PubMed ID: 14713345	2004
Pulmonary antioxidant defenses in the preterm newborn with respiratory distress and bronchopulmonary dysplasia in evolution: implications for antioxidant therapy. Antioxidants & redox signaling\| PubMed ID: 14713347	2004
Cigarette smoke extract increases S-adenosylmethionine and cystathionine in human lung epithelial-like (A549) cells. Chemico-biological interactions\| PubMed ID: 14726155	2004
Extracellular ATP-mediated signaling for survival in hyperoxia-induced oxidative stress. The Journal of biological chemistry\| PubMed ID: 14761947	2004
Antioxidant defenses in the preterm lung: role for hypoxia-inducible factors in BPD? Toxicology and applied pharmacology\| PubMed ID: 15710178	2005
Stimulation of HIF-1alpha, HIF-2alpha, and VEGF by prolyl 4-hydroxylase inhibition in human lung endothelial and epithelial cells. Free radical biology & medicine\| PubMed ID: 15780758	2005
Lung epithelial cells release ATP during ozone exposure: signaling for cell survival. Free radical biology & medicine\| PubMed ID: 15964513	2005
Activation of hypoxia-inducible factors in hyperoxia through prolyl 4-hydroxylase blockade in cells and explants of primate lung. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16009933	2005
Thioredoxin and dihydrolipoic acid inhibit elastase activity in cystic fibrosis sputum. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 16214824	2005
Effect of preterm birth on hypoxia-inducible factors and vascular endothelial growth factor in primate lungs. Pediatric pulmonology\| PubMed ID: 16231377	2005
Extracellular adenosine triphosphate: a potential regulator of vasa vasorum neovascularization in hypoxia-induced pulmonary vascular remodeling. Chest\| PubMed ID: 16373860	2005
Activation of a novel isoform of methionine adenosyl transferase 2A and increased S-adenosylmethionine turnover in lung epithelial cells exposed to hyperoxia. Free radical biology & medicine\| PubMed ID: 16413417	2006
Cholesterol interferes with the MTT assay in human epithelial-like (A549) and endothelial (HLMVE and HCAE) cells. International journal of toxicology\| PubMed ID: 16510353	2006
Commentary on "Hypoxia, hypoxic signaling, tissue damage, and detection of reactive oxygen species (ROS)". Free radical biology & medicine\| PubMed ID: 16540387	2006
Endothelial Akt activation by hyperoxia: role in cell survival. Free radical biology & medicine\| PubMed ID: 16545678	2006
Enhancement of angiogenic effectors through hypoxia-inducible factor in preterm primate lung in vivo. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 16679381	2006
Purinergic signaling and kinase activation for survival in pulmonary oxidative stress and disease. Free radical biology & medicine\| PubMed ID: 16781450	2006
Improved lung growth and function through hypoxia-inducible factor in primate chronic lung disease of prematurity. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 16807366	2006
Multislice computed tomography for determination of coronary artery disease in a symptomatic patient population. The international journal of cardiovascular imaging\| PubMed ID: 17160425	2007
Effect of cell cycle growth arrest on global DNA methylation status in human lung epithelial-like (A549) cells. In vivo (Athens, Greece)\| PubMed ID: 17203780	2006
Hypoxia-inducible factors HIF-1alpha and HIF-2alpha are decreased in an experimental model of severe respiratory distress syndrome in preterm lambs. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 17307811	2007
Reduced thioredoxin increases proinflammatory cytokines and neutrophil influx in rat airways: modulation by airway mucus. Free radical biology & medicine\| PubMed ID: 17395017	2007
HIF stabilizing agents: shotgun or scalpel? American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 17616644	2007
Lipoic acid suppression of neutrophil respiratory burst: effect of NADPH. Antioxidants & redox signaling\| PubMed ID: 18158760	2008
Oxidative stress-induced regulation of the methionine metabolic pathway in human lung epithelial-like (A549) cells. Mutation research\| PubMed ID: 19010443	2009
A role for mitochondrial oxidative stress in sulfur mustard analog 2-chloroethyl ethyl sulfide-induced lung cell injury and antioxidant protection. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 19064720	2009
Inflammatory biomarkers of sulfur mustard analog 2-chloroethyl ethyl sulfide-induced skin injury in SKH-1 hairless mice. Toxicological sciences : an official journal of the Society of Toxicology\| PubMed ID: 19075041	2009
Bcl-2 suppresses sarcoplasmic/endoplasmic reticulum Ca2+-ATPase expression in cystic fibrosis airways: role in oxidant-mediated cell death. American journal of respiratory and critical care medicine\| PubMed ID: 19201925	2009
Adenosine A2A receptor is a unique angiogenic target of HIF-2alpha in pulmonary endothelial cells. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19541651	2009
Alpha-lipoic acid induces elevated S-adenosylhomocysteine and depletes S-adenosylmethionine. Free radical biology & medicine\| PubMed ID: 19616616	2009
Sulfur mustard analog induces oxidative stress and activates signaling cascades in the skin of SKH-1 hairless mice. Free radical biology & medicine\| PubMed ID: 19761830	2009
Treatment with the catalytic metalloporphyrin AEOL 10150 reduces inflammation and oxidative stress due to inhalation of the sulfur mustard analog 2-chloroethyl ethyl sulfide. Free radical biology & medicine\| PubMed ID: 20138141	2010
Characterisation of the prostanoid receptor mediating inhibition of smooth muscle contractility in the rat prostate gland. Naunyn-Schmiedeberg's archives of pharmacology\| PubMed ID: 20180098	2010
Biological and molecular mechanisms of sulfur mustard analogue-induced toxicity in JB6 and HaCaT cells: possible role of ataxia telangiectasia-mutated/ataxia telangiectasia-Rad3-related cell... Chemical research in toxicology\| PubMed ID: 20469912	2010
Chlorine gas inhalation: human clinical evidence of toxicity and experience in animal models. Proceedings of the American Thoracic Society\| PubMed ID: 20601629	2010
Airway obstruction due to bronchial vascular injury after sulfur mustard analog inhalation. American journal of respiratory and critical care medicine\| PubMed ID: 20639443	2010
The residual nonadrenergic contractile response to nerve stimulation of the mouse prostate is mediated by acetylcholine but not ATP in a comparison with the mouse vas deferens. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 20724483	2010
Dimethylthiourea protects against chlorine induced changes in airway function in a murine model of irritant induced asthma. Respiratory research\| PubMed ID: 20925946	2010
Efficacy of glutathione in ameliorating sulfur mustard analog-induced toxicity in cultured skin epidermal cells and in SKH-1 mouse skin in vivo. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 20974699	2011
Expression of Transcription Factor GATA-6 in Alveolar Epithelial Cells Is Linked to Neonatal Lung Disease. Neonatology\| PubMed ID: 21071980	2011
AEOL10150: a novel therapeutic for rescue treatment after toxic gas lung injury. Free radical biology & medicine\| PubMed ID: 21156205	2011
2-Chloroethyl ethyl sulfide causes microvesication and inflammation-related histopathological changes in male hairless mouse skin. Toxicology\| PubMed ID: 21295104	2011
Role of reactive oxygen and nitrogen species in olfactory epithelial injury by the sulfur mustard analogue 2-chloroethyl ethyl sulfide. American journal of respiratory cell and molecular biology\| PubMed ID: 21642592	2011
Sulfur mustard analog, 2-chloroethyl ethyl sulfide-induced skin injury involves DNA damage and induction of inflammatory mediators, in part via oxidative stress, in SKH-1 hairless mouse skin... Toxicology letters\| PubMed ID: 21722719	2011
Contractions of the mouse prostate elicited by acetylcholine are mediated by M(3) muscarinic receptors. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 21885618	2011
Mechanisms of sulfur mustard analog 2-chloroethyl ethyl sulfide-induced DNA damage in skin epidermal cells and fibroblasts. Free radical biology & medicine\| PubMed ID: 21920433	2011
Airway tissue factor-dependent coagulation activity in response to sulfur mustard analog 2-chloroethyl ethyl sulfide. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 21964405	2012
Interaction and localization of synthetic nanoparticles in healthy and cystic fibrosis airway epithelial cells: effect of ozone exposure. Journal of aerosol medicine and pulmonary drug delivery\| PubMed ID: 22007674	2012
SERCA2 regulates non-CF and CF airway epithelial cell response to ozone. PloS one\| PubMed ID: 22096575	2011
Identification and profiling of novel α1A-adrenoceptor-CXC chemokine receptor 2 heteromer. The Journal of biological chemistry\| PubMed ID: 22371491	2012
Suicidal ideation and thought disorder associated with the formoterol component of combined asthma medication. Pediatric pulmonology\| PubMed ID: 22489078	2013
Tissue Factor Signals Airway Epithelial Basal Cell Survival via Coagulation and PAR1/2. American journal of respiratory cell and molecular biology\| PubMed ID: 23065128	2012
Tissue plasminogen activator prevents mortality from sulfur mustard analog-induced airway obstruction. American journal of respiratory cell and molecular biology\| PubMed ID: 23258228	2013
Differential regulation of pulmonary vascular cell growth by hypoxia-inducible transcription factor-1α and hypoxia-inducible transcription factor-2α. American journal of respiratory cell and molecular biology\| PubMed ID: 23492195	2013
Adenosine A2A receptor-dependent proliferation of pulmonary endothelial cells is mediated through calcium mobilization, PI3-kinase and ERK1/2 pathways. Biochemical and biophysical research communications\| PubMed ID: 23583199	2013
Tissue factor pathway inhibitor prevents airway obstruction, respiratory failure and death due to sulfur mustard analog inhalation. Toxicology and applied pharmacology\| PubMed ID: 23727623	2013
Clinically-relevant cutaneous lesions by nitrogen mustard: useful biomarkers of vesicants skin injury in SKH-1 hairless and C57BL/6 mice. PloS one\| PubMed ID: 23826320	2013
Absence of a p53 allele delays nitrogen mustard-induced early apoptosis and inflammation of murine skin. Toxicology\| PubMed ID: 23845566	2013
Impact of SOD-Mimetic Manganoporphyrins on Spin Trapping of Superoxide and Related Artifacts. Applied magnetic resonance\| PubMed ID: 23853422	2011
Age-related changes in the innervation of the prostate gland: implications for prostate cancer initiation and progression. Organogenesis\| PubMed ID: 23872639	2013
Human tracheobronchial basal cells. Normal versus remodeling/repairing phenotypes in vivo and in vitro. American journal of respiratory cell and molecular biology\| PubMed ID: 23927678	2013
Rho kinase activation mediates adrenergic and cholinergic smooth muscle contractile responses in the mouse prostate gland. European journal of pharmacology\| PubMed ID: 24055190	2013
Development of a P2X1-purinoceptor mediated contractile response in the aged mouse prostate gland through slowing down of ATP breakdown. Neurourology and urodynamics\| PubMed ID: 24249481	2013
Male contraception via simultaneous knockout of α1A-adrenoceptors and P2X1-purinoceptors in mice. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 24297884	2013
Transcriptome profiling of the newborn mouse lung response to acute ozone exposure. Toxicological sciences : an official journal of the Society of Toxicology\| PubMed ID: 24336422	2014
Histopathological and immunohistochemical evaluation of nitrogen mustard-induced cutaneous effects in SKH-1 hairless and C57BL/6 mice. Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie\| PubMed ID: 24373750	2014
Humidifier and environmental "chILD" risks. American journal of respiratory and critical care medicine\| PubMed ID: 24381989	2014
Cutaneous injury-related structural changes and their progression following topical nitrogen mustard exposure in hairless and haired mice. PloS one\| PubMed ID: 24416404	2014
Myeloperoxidase deficiency attenuates nitrogen mustard-induced skin injuries. Toxicology\| PubMed ID: 24631667	2014
Intratracheal heparin improves plastic bronchitis due to sulfur mustard analog. Pediatric pulmonology\| PubMed ID: 24692161	2014
Activation of DNA damage repair pathways in response to nitrogen mustard-induced DNA damage and toxicity in skin keratinocytes. Mutation research\| PubMed ID: 24732344	2014
Antifibrinolytic Mechanisms in Acute Airway Injury following Sulfur Mustard Analog Inhalation. American journal of respiratory cell and molecular biology\| PubMed ID: 24796565	2014