Laurence G. Rahme

Shriners Burn Institute

Affiliated withShriners Burn Institute Massachusetts General Hospital, Harvard Medical School

Research Area

Biography

Laurence G. Rahme has not added Biography.
If you are Laurence G. Rahme and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 5	2010

Other Publications

Article	Year
Identification of virulence genes in a pathogenic strain of Pseudomonas aeruginosa by representational difference analysis. Journal of bacteriology\| PubMed ID: 11807055	2002
Use of plant and insect hosts to model bacterial pathogenesis. Methods in enzymology\| PubMed ID: 12474375	2002
The Drosophila melanogaster toll pathway participates in resistance to infection by the gram-negative human pathogen Pseudomonas aeruginosa. Infection and immunity\| PubMed ID: 12819096	2003
Pseudomonas aeruginosa-plant root interactions. Pathogenicity, biofilm formation, and root exudation. Plant physiology\| PubMed ID: 14701912	2004
Analysis of Pseudomonas aeruginosa 4-hydroxy-2-alkylquinolines (HAQs) reveals a role for 4-hydroxy-2-heptylquinoline in cell-to-cell communication. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 14739337	2004
The broad host range pathogen Pseudomonas aeruginosa strain PA14 carries two pathogenicity islands harboring plant and animal virulence genes. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 14983043	2004
Challenge of Drosophila melanogaster with Cryptococcus neoformans and role of the innate immune response. Eukaryotic cell\| PubMed ID: 15075271	2004
Electrospray/mass spectrometric identification and analysis of 4-hydroxy-2-alkylquinolines (HAQs) produced by Pseudomonas aeruginosa. Journal of the American Society for Mass Spectrometry\| PubMed ID: 15144975	2004
The contribution of MvfR to Pseudomonas aeruginosa pathogenesis and quorum sensing circuitry regulation: multiple quorum sensing-regulated genes are modulated without affecting lasRI, rhlRI ... Molecular microbiology\| PubMed ID: 15686549	2005
Profiling early infection responses: Pseudomonas aeruginosa eludes host defenses by suppressing antimicrobial peptide gene expression. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15695583	2005
Burn injury causes mitochondrial dysfunction in skeletal muscle. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15809440	2005
Proton NMR spectroscopy shows lipids accumulate in skeletal muscle in response to burn trauma-induced apoptosis. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 16126910	2005
Mutation analysis of the Pseudomonas aeruginosa mvfR and pqsABCDE gene promoters demonstrates complex quorum-sensing circuitry. Microbiology (Reading, England)\| PubMed ID: 16735731	2006
Local and distant burn injury alter immuno-inflammatory gene expression in skeletal muscle. The Journal of trauma\| PubMed ID: 16917440	2006
Genomic analysis reveals that Pseudomonas aeruginosa virulence is combinatorial. Genome biology\| PubMed ID: 17038190	2006
MvfR, a key Pseudomonas aeruginosa pathogenicity LTTR-class regulatory protein, has dual ligands. Molecular microbiology\| PubMed ID: 17083468	2006
Uncoupling protein 3 expression and intramyocellular lipid accumulation by NMR following local burn trauma. International journal of molecular medicine\| PubMed ID: 17089030	2006
Dynorphin activates quorum sensing quinolone signaling in Pseudomonas aeruginosa. PLoS pathogens\| PubMed ID: 17367209	2007
Combination of high-resolution magic angle spinning proton magnetic resonance spectroscopy and microscale genomics to type brain tumor biopsies. International journal of molecular medicine\| PubMed ID: 17611638	2007
PqsA is required for the biosynthesis of 2,4-dihydroxyquinoline (DHQ), a newly identified metabolite produced by Pseudomonas aeruginosa and Burkholderia thailandensis. Biological chemistry\| PubMed ID: 17655503	2007
Inhibitors of pathogen intercellular signals as selective anti-infective compounds. PLoS pathogens\| PubMed ID: 17941706	2007
Involvement of skeletal muscle gene regulatory network in susceptibility to wound infection following trauma. PloS one\| PubMed ID: 18159239	2007
Reduced rate of adenosine triphosphate synthesis by in vivo 31P nuclear magnetic resonance spectroscopy and downregulation of PGC-1beta in distal skeletal muscle following burn. International journal of molecular medicine\| PubMed ID: 18204786	2008
Use of the lambda Red recombinase system to rapidly generate mutants in Pseudomonas aeruginosa. BMC molecular biology\| PubMed ID: 18248677	2008
Murine intramyocellular lipids quantified by NMR act as metabolic biomarkers in burn trauma. International journal of molecular medicine\| PubMed ID: 18506378	2008
Modeling Pseudomonas aeruginosa pathogenesis in plant hosts. Nature protocols\| PubMed ID: 19180083	2009
Microarray analysis suggests that burn injury results in mitochondrial dysfunction in human skeletal muscle. International journal of molecular medicine\| PubMed ID: 19639232	2009
Drosophila melanogaster as a model host for studying Pseudomonas aeruginosa infection. Nature protocols\| PubMed ID: 19680242	2009
Dysfunctional expansion of hematopoietic stem cells and block of myeloid differentiation in lethal sepsis. Blood\| PubMed ID: 19696201	2009
The pathogenic properties of a novel and conserved gene product, KerV, in proteobacteria. PloS one\| PubMed ID: 19779606	2009
Homeostatic interplay between bacterial cell-cell signaling and iron in virulence. PLoS pathogens\| PubMed ID: 20300606	2010
In vivo high-resolution magic angle spinning magnetic resonance spectroscopy of Drosophila melanogaster at 14.1 T shows trauma in aging and in innate immune-deficiency is linked to reduced i... International journal of molecular medicine\| PubMed ID: 20596596	2010
Combined off-resonance imaging and T2 relaxation in the rotating frame for positive contrast MR imaging of infection in a murine burn model. Journal of magnetic resonance imaging : JMRI\| PubMed ID: 21031524	2010
Nuclear magnetic resonance in conjunction with functional genomics suggests mitochondrial dysfunction in a murine model of cancer cachexia. International journal of molecular medicine\| PubMed ID: 21069263	2011
Burn trauma in skeletal muscle results in oxidative stress as assessed by in vivo electron paramagnetic resonance. Molecular medicine reports\| PubMed ID: 21179378	2008
Drosophila melanogaster as a model for human intestinal infection and pathology. Disease models & mechanisms\| PubMed ID: 21183483	2011
Combining magnetic resonance spectroscopy and molecular genomics offers better accuracy in brain tumor typing and prediction of survival than either methodology alone. International journal of oncology\| PubMed ID: 21274507	2011
A quorum sensing regulated small volatile molecule reduces acute virulence and promotes chronic infection phenotypes. PLoS pathogens\| PubMed ID: 21829370	2011
Down-regulation of glutatione S-transferase Î± 4 (hGSTA4) in the muscle of thermally injured patients is indicative of susceptibility to bacterial infection. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 22038048	2012