Carole L. Yauk

Environmental Health Science and Research Bureau, Environmental Health Centre

Affiliated withEnvironmental Health Centre Health Canada

Research Area

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 28	2014
Publication title Cited by 14	2015

Other Publications

Article	Year
A novel single molecule analysis of spontaneous and radiation-induced mutation at a mouse tandem repeat locus. Mutation research\| PubMed ID: 11890944	2002
Air pollution induces heritable DNA mutations. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12473746	2002
Advances in the application of germline tandem repeat instability for in situ monitoring. Mutation research\| PubMed ID: 15164979	2004
Comprehensive comparison of six microarray technologies. Nucleic acids research\| PubMed ID: 15333675	2004
A lacZ transgenic mouse assay for the detection of mutations in follicular granulosa cells. Mutation research\| PubMed ID: 16039675	2005
Instability of expanded simple tandem repeats is induced in cell culture by a variety of agents: N-Nitroso-N-ethylurea, benzo(a)pyrene, etoposide and okadaic acid. Mutation research\| PubMed ID: 16516931	2006
Detection of induced male germline mutation: correlations and comparisons between traditional germline mutation assays, transgenic rodent assays and expanded simple tandem repeat instability... Mutation research\| PubMed ID: 16542687	2006
Novel design and controls for focused DNA microarrays: applications in quality assurance/control and normalization for the Health Canada ToxArray. BMC genomics\| PubMed ID: 17052352	2006
Review of the literature examining the correlation among DNA microarray technologies. Environmental and molecular mutagenesis\| PubMed ID: 17370338	2007
Hepatic gene expression changes in hypothyroid juvenile mice: characterization of a novel negative thyroid-responsive element. Endocrinology\| PubMed ID: 17463053	2007
Mainstream tobacco smoke causes paternal germ-line DNA mutation. Cancer research\| PubMed ID: 17545587	2007
Analysis of gene expression in two human-derived cell lines exposed in vitro to a 1.9 GHz pulse-modulated radiofrequency field. Proteomics\| PubMed ID: 17902192	2007
Tandem repeat mutation, global DNA methylation, and regulation of DNA methyltransferases in cultured mouse embryonic fibroblast cells chronically exposed to chemicals with different modes of... Environmental and molecular mutagenesis\| PubMed ID: 18172875	2008
Toxicogenomic analysis of mainstream tobacco smoke-exposed mice reveals repression of plasminogen activator inhibitor-1 gene in heart. Inhalation toxicology\| PubMed ID: 18925475	2009
Identification of thyroid hormone receptor binding sites and target genes using ChIP-on-chip in developing mouse cerebellum. PloS one\| PubMed ID: 19240802	2009
Toxicogenomic analysis of susceptibility to inhaled urban particulate matter in mice with chronic lung inflammation. Particle and fibre toxicology\| PubMed ID: 19284582	2009
Impact of nose-only exposure system on pulmonary gene expression. Inhalation toxicology\| PubMed ID: 19558237	2009
Induction of the interleukin 6/ signal transducer and activator of transcription pathway in the lungs of mice sub-chronically exposed to mainstream tobacco smoke. BMC medical genomics\| PubMed ID: 19698101	2009
Cross-platform analysis of global microRNA expression technologies. BMC genomics\| PubMed ID: 20504329	2010
Acetaminophen modulates the transcriptional response to recombinant interferon-beta. PloS one\| PubMed ID: 20544007	2010
Germ cell mutagens: risk assessment challenges in the 21st century. Environmental and molecular mutagenesis\| PubMed ID: 20740630	2010
Pulmonary response to surface-coated nanotitanium dioxide particles includes induction of acute phase response genes, inflammatory cascades, and changes in microRNAs: a toxicogenomic study. Environmental and molecular mutagenesis\| PubMed ID: 21259345	2011
Assessment of subclinical, toxicant-induced hepatic gene expression profiles after low-dose, short-term exposures in mice. Regulatory toxicology and pharmacology : RTP\| PubMed ID: 21335049	2011
Germline mutation rates in mice following in utero exposure to diesel exhaust particles by maternal inhalation. Mutation research\| PubMed ID: 21570989	2011
Sidestream tobacco smoke is a male germ cell mutagen. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 21768363	2011
Hepatic mRNA, microRNA, and miR-34a-target responses in mice after 28 days exposure to doses of benzo(a)pyrene that elicit DNA damage and mutation. Environmental and molecular mutagenesis\| PubMed ID: 21964900	2012
Technical-grade perfluorooctane sulfonate alters the expression of more transcripts in cultured chicken embryonic hepatocytes than linear perfluorooctane sulfonate. Environmental toxicology and chemistry / SETAC\| PubMed ID: 21994020	2011
Exposure of pregnant mice to carbon black by intratracheal instillation: Toxicogenomic effects in dams and offspring. Mutation research\| PubMed ID: 22001195	2011
Barhl1 is directly regulated by thyroid hormone in the developing cerebellum of mice. Biochemical and biophysical research communications\| PubMed ID: 22027146	2011
Thyroid hormone-regulated gene expression in juvenile mouse liver: identification of thyroid response elements using microarray profiling and in silico analyses. BMC genomics\| PubMed ID: 22206413	2011
Carbon black nanoparticle instillation induces sustained inflammation and genotoxicity in mouse lung and liver. Particle and fibre toxicology\| PubMed ID: 22300514	2012
Overexpression of tumor necrosis factor-α in the lungs alters immune response, matrix remodeling, and repair and maintenance pathways. The American journal of pathology\| PubMed ID: 22322299	2012
Genetic toxicology and toxicogenomic analysis of three cigarette smoke condensates in vitro reveals few differences among full-flavor, blonde, and light products. Environmental and molecular mutagenesis\| PubMed ID: 22431010	2012
Supplemental dietary folic acid has no effect on chromosome damage in erythrocyte progenitor cells of mice. The Journal of nutrition\| PubMed ID: 22437555	2012
Hepatic and pulmonary toxicogenomic profiles in mice intratracheally instilled with carbon black nanoparticles reveal pulmonary inflammation, acute phase response, and alterations in lipid h... Toxicological sciences : an official journal of the Society of Toxicology\| PubMed ID: 22461453	2012
NanoTIO(2) (UV-Titan) does not induce ESTR mutations in the germline of prenatally exposed female mice. Particle and fibre toxicology\| PubMed ID: 22656316	2012
Carbon black nanoparticle intratracheal installation results in large and sustained changes in the expression of miR-135b in mouse lung. Environmental and molecular mutagenesis\| PubMed ID: 22753103	2012
Transcriptional profiles in the cerebral hemisphere of chicken embryos following in ovo perfluorohexane sulfonate exposure. Toxicological sciences : an official journal of the Society of Toxicology\| PubMed ID: 22790973	2012
Investigating the effects of dietary folic acid on sperm count, DNA damage and mutation in Balb/c mice. Mutation research\| PubMed ID: 22824165	2012
Gene expression profiling to identify potentially relevant disease outcomes and support human health risk assessment for carbon black nanoparticle exposure. Toxicology\| PubMed ID: 23146762	2013
The development of adverse outcome pathways for mutagenic effects for the organization for economic co-operation and development. Environmental and molecular mutagenesis\| PubMed ID: 23355186	2013
IL-1 receptor regulates microRNA-135b expression in a negative feedback mechanism during cigarette smoke-induced inflammation. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 23440414	2013
Building on the past, shaping the future: the Environmental Mutagenesis and Genomics Society. Environmental and molecular mutagenesis\| PubMed ID: 23444128	2013
Preparation of archival formalin-fixed paraffin-embedded mouse liver samples for use with the Agilent gene expression microarray platform. Journal of pharmacological and toxicological methods\| PubMed ID: 23458726	2013
No evidence for transgenerational genomic instability in the F1 or F2 descendants of Muta™Mouse males exposed to N-ethyl-N-nitrosourea. Mutation research\| PubMed ID: 23499255	2013
Mice exposed in situ to urban air pollution exhibit pulmonary alterations in gene expression in the lipid droplet synthesis pathways. Environmental and molecular mutagenesis\| PubMed ID: 23536514	2013
A global toxicogenomic analysis investigating the mechanistic differences between tobacco and marijuana smoke condensates in vitro. Toxicology\| PubMed ID: 23542559	2013
Pulmonary instillation of low doses of titanium dioxide nanoparticles in mice leads to particle retention and gene expression changes in the absence of inflammation. Toxicology and applied pharmacology\| PubMed ID: 23557971	2013
In vitro microarray analysis identifies genes in acute-phase response pathways that are down-regulated in the liver of chicken embryos exposed in ovo to PFUdA. Toxicology in vitro : an international journal published in association with BIBRA\| PubMed ID: 23602845	2013
Identification of thyroid hormone receptor binding sites in developing mouse cerebellum. BMC genomics\| PubMed ID: 23701648	2013
Toxicogenomic outcomes predictive of forestomach carcinogenesis following exposure to benzo(a)pyrene: relevance to human cancer risk. Toxicology and applied pharmacology\| PubMed ID: 23735875	2013
Hepatic genotoxicity and toxicogenomic responses in Muta™Mouse males treated with dibenz[a,h]anthracene. Mutagenesis\| PubMed ID: 23793610	2013
Differential expression of long noncoding RNAs in the livers of female B6C3F1 mice exposed to the carcinogen furan. Toxicological sciences : an official journal of the Society of Toxicology\| PubMed ID: 23853263	2013
In utero exposure to nanosized carbon black (Printex90) does not induce tandem repeat mutations in female murine germ cells. Reproductive toxicology (Elmsford, N.Y.)\| PubMed ID: 23871697	2013
Incorporating new technologies into toxicity testing and risk assessment: moving from 21st century vision to a data-driven framework. Toxicological sciences : an official journal of the Society of Toxicology\| PubMed ID: 23958734	2013
Carbon black nanoparticle intratracheal instillation does not alter cardiac gene expression. Cardiovascular toxicology\| PubMed ID: 24078381	2013
Case study on the utility of hepatic global gene expression profiling in the risk assessment of the carcinogen furan. Toxicology and applied pharmacology\| PubMed ID: 24183702	2014
Transcriptomic analysis reveals novel mechanistic insight into murine biological responses to multi-walled carbon nanotubes in lungs and cultured lung epithelial cells. PloS one\| PubMed ID: 24260392	2013
Tris(1,3-dichloro-2-propyl) phosphate perturbs the expression of genes involved in immune response and lipid and steroid metabolism in chicken embryos. Toxicology and applied pharmacology\| PubMed ID: 24407104	2014
Transient Maternal Hypothyroxinemia Potentiates the Transcriptional Response to Exogenous Thyroid Hormone in the Fetal Cerebral Cortex Before the Onset of Fetal Thyroid Function: A Messenger... Cerebral cortex (New York, N.Y. : 1991)\| PubMed ID: 24436321	2014
Bromodeoxyuridine (BrdU) treatment to measure hepatocellular proliferation does not mask furan-induced gene expression changes in mouse liver. Toxicology\| PubMed ID: 24910943	2014
Particle-induced pulmonary acute phase response may be the causal link between particle inhalation and cardiovascular disease. Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology\| PubMed ID: 24920450	2014
Thyroid hormone response element half-site organization and its effect on thyroid hormone mediated transcription. PloS one\| PubMed ID: 24971931	2014
Identification of mechanisms of action of bisphenol A-induced human preadipocyte differentiation by transcriptional profiling. Obesity (Silver Spring, Md.)\| PubMed ID: 25047013	2014