Christoph Korbmacher

Institut für Zelluläre und Molekulare Physiologie, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU)

Affiliated withFriedrich-Alexander-Universität Erlangen-Nürnberg (FAU)

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 4	2014

Other Publications

Article	Year
Sensitisation of TRPV4 by PAR2 is independent of intracellular calcium signalling and can be mediated by the biased agonist neutrophil elastase. Pflugers Archiv : European journal of physiology\| PubMed ID: 24906497	2014
Basolateral PAR-2 receptors mediate KCl secretion and inhibition of Na+ absorption in the mouse distal colon. The Journal of physiology\| PubMed ID: 11850514	2002
Intrinsic sensitivity of Kir1.1 (ROMK) to glibenclamide in the absence of SUR2B. Implications for the identity of the renal ATP-regulated secretory K+ channel. The Journal of biological chemistry\| PubMed ID: 11927600	2002
Cystic fibrosis transmembrane conductance regulator-dependent up-regulation of Kir1.1 (ROMK) renal K+ channels by the epithelial sodium channel. The Journal of biological chemistry\| PubMed ID: 11994290	2002
Regulation of the epithelial sodium channel by N4WBP5A, a novel Nedd4/Nedd4-2-interacting protein. The Journal of biological chemistry\| PubMed ID: 12050153	2002
The role of individual Nedd4-2 (KIAA0439) WW domains in binding and regulating epithelial sodium channels. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 12424229	2003
The serum and glucocorticoid-inducible kinase SGK1 and the Na+/H+ exchange regulating factor NHERF2 synergize to stimulate the renal outer medullary K+ channel ROMK1. Journal of the American Society of Nephrology : JASN\| PubMed ID: 12444200	2002
Identification of domains that control the heteromeric assembly of Kir5.1/Kir4.0 potassium channels. American journal of physiology. Cell physiology\| PubMed ID: 12456399	2003
Basolateral adrenoceptor activation mediates noradrenaline-induced Cl- secretion in M-1 mouse cortical collecting duct cells. Pflügers Archiv : European journal of physiology\| PubMed ID: 12466941	2002
The gamma-subunit of ENaC is more important for channel surface expression than the beta-subunit. American journal of physiology. Cell physiology\| PubMed ID: 12529252	2003
cAMP-dependent activation of CFTR inhibits the epithelial sodium channel (ENaC) without affecting its surface expression. Pflügers Archiv : European journal of physiology\| PubMed ID: 12548398	2003
Extracellular Na+ removal attenuates rundown of the epithelial Na+-channel (ENaC) by reducing the rate of channel retrieval. Pflügers Archiv : European journal of physiology\| PubMed ID: 14704795	2004
Additional disruption of the ClC-2 Cl(-) channel does not exacerbate the cystic fibrosis phenotype of cystic fibrosis transmembrane conductance regulator mouse models. The Journal of biological chemistry\| PubMed ID: 15007059	2004
PGE2 stimulates Cl- secretion in murine M-1 cortical collecting duct cells in an autocrine manner. Pflügers Archiv : European journal of physiology\| PubMed ID: 15127302	2004
A novel pathway of epithelial sodium channel activation involves a serum- and glucocorticoid-inducible kinase consensus motif in the C terminus of the channel's alpha-subunit. The Journal of biological chemistry\| PubMed ID: 15234985	2004
Stimulation of the epithelial sodium channel (ENaC) by the serum- and glucocorticoid-inducible kinase (Sgk) involves the PY motifs of the channel but is independent of sodium feedback inhibi... Pflügers Archiv : European journal of physiology\| PubMed ID: 16416336	2006
Stimulation of the epithelial sodium channel (ENaC) by cAMP involves putative ERK phosphorylation sites in the C termini of the channel's beta- and gamma-subunit. The Journal of biological chemistry\| PubMed ID: 16476738	2006
Functional characterization of a novel CFTR mutation P67S identified in a patient with atypical cystic fibrosis. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology\| PubMed ID: 17495464	2007
(NDRG2) stimulates amiloride-sensitive Na+ currents in Xenopus laevis oocytes and fisher rat thyroid cells. The Journal of biological chemistry\| PubMed ID: 17652085	2007
Aldosterone responsiveness of the epithelial sodium channel (ENaC) in colon is increased in a mouse model for Liddle's syndrome. The Journal of physiology\| PubMed ID: 18006588	2008
Trypsin can activate the epithelial sodium channel (ENaC) in microdissected mouse distal nephron. American journal of physiology. Renal physiology\| PubMed ID: 18653483	2008
Cleavage in the {gamma}-subunit of the epithelial sodium channel (ENaC) plays an important role in the proteolytic activation of near-silent channels. The Journal of physiology\| PubMed ID: 18669538	2008
Plasmin in nephrotic urine activates the epithelial sodium channel. Journal of the American Society of Nephrology : JASN\| PubMed ID: 19073825	2009
Regulated sodium transport in the renal connecting tubule (CNT) via the epithelial sodium channel (ENaC). Pflügers Archiv : European journal of physiology\| PubMed ID: 19277701	2009
HIF-prolyl hydroxylases in the rat kidney: physiologic expression patterns and regulation in acute kidney injury. The American journal of pathology\| PubMed ID: 19349364	2009
Mutations in the amiloride-sensitive epithelial sodium channel in patients with cystic fibrosis-like disease. Human mutation\| PubMed ID: 19462466	2009
The delta-subunit of the epithelial sodium channel (ENaC) enhances channel activity and alters proteolytic ENaC activation. The Journal of biological chemistry\| PubMed ID: 19717556	2009
Cholesterol depletion of the plasma membrane prevents activation of the epithelial sodium channel (ENaC) by SGK1. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology\| PubMed ID: 19910701	2009
Functional characterization of a partial loss-of-function mutation of the epithelial sodium channel (ENaC) associated with atypical cystic fibrosis. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology\| PubMed ID: 20054153	2010
A mutation of the epithelial sodium channel associated with atypical cystic fibrosis increases channel open probability and reduces Na+ self inhibition. The Journal of physiology\| PubMed ID: 20194130	2010
Proteolytic activation of the epithelial sodium channel (ENaC) in health and disease. The journal of medical investigation : JMI\| PubMed ID: 20224211	2009
Protein kinase B alpha (PKBα) stimulates the epithelial sodium channel (ENaC) heterologously expressed in Xenopus laevis oocytes by two distinct mechanisms. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology\| PubMed ID: 21220922	2010
Atomic force microscopy reveals the architecture of the epithelial sodium channel (ENaC). The Journal of biological chemistry\| PubMed ID: 21775436	2011
Four subunits (αβγδ) of the epithelial sodium channel (ENaC) are expressed in the human eye in various locations. Investigative ophthalmology & visual science\| PubMed ID: 22167092	2012
An inhibitory peptide derived from the α-subunit of the epithelial sodium channel (ENaC) shows a helical conformation. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology\| PubMed ID: 22613977	2012
Proteolytic activation of the epithelial sodium channel (ENaC) by the cysteine protease cathepsin-S. Pflügers Archiv : European journal of physiology\| PubMed ID: 22864553	2012
Aldosterone-dependent and -independent regulation of the epithelial sodium channel (ENaC) in mouse distal nephron. American journal of physiology. Renal physiology\| PubMed ID: 22933298	2012
Plasmin and chymotrypsin have distinct preferences for channel activating cleavage sites in the γ subunit of the human epithelial sodium channel. The Journal of general physiology\| PubMed ID: 22966015	2012
A mutation in the β-subunit of ENaC identified in a patient with cystic fibrosis-like symptoms has a gain-of-function effect. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 23087020	2013
Characterization of the mouse ClC-K1/Barttin chloride channel. Biochimica et biophysica acta\| PubMed ID: 23791703	2013
The bile acid receptor TGR5 does not interact with β-arrestins or traffic to endosomes but transmits sustained signals from plasma membrane rafts. The Journal of biological chemistry\| PubMed ID: 23818521	2013
Pharmacological and electrophysiological characterization of the human bile acid-sensitive ion channel (hBASIC). Pflügers Archiv : European journal of physiology\| PubMed ID: 23842738	2014
Proteolytic Activation of the Human Epithelial Sodium Channel by Trypsin IV and Trypsin I Involves Distinct Cleavage Sites. The Journal of biological chemistry\| PubMed ID: 24841206	2014