Farrah Kheradmand

Department of Medicine, Baylor College of Medicine (BCM)

Affiliated withBaylor College of Medicine (BCM)Baylor College of Medicine Michael E. DeBakey VA Medical Center

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 10	2010
Publication title Cited by 19	2020

Other Publications

Article	Year
Shedding light on sheddases: role in growth and development. BioEssays : news and reviews in molecular, cellular and developmental biology\| PubMed ID: 11782944	2002
Signaling through the EGF receptor controls lung morphogenesis in part by regulating MT1-MMP-mediated activation of gelatinase A/MMP2. Journal of cell science\| PubMed ID: 11865039	2002
Decreased allergic lung inflammatory cell egression and increased susceptibility to asphyxiation in MMP2-deficiency. Nature immunology\| PubMed ID: 11887181	2002
Gene therapy of mucus hypersecretion in experimental asthma. Chest\| PubMed ID: 11893719	2002
Environmental contributions to the allergic asthma epidemic. Environmental health perspectives\| PubMed ID: 12194885	2002
A protease-activated pathway underlying Th cell type 2 activation and allergic lung disease. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 12421974	2002
16. Immunologic lung disease. The Journal of allergy and clinical immunology\| PubMed ID: 12592307	2003
Differential requirement for CD18 in T-helper effector homing. Nature medicine\| PubMed ID: 14502280	2003
Airway glycoprotein secretion parallels production and predicts airway obstruction in pulmonary allergy. The Journal of allergy and clinical immunology\| PubMed ID: 14713910	2004
Biology and therapeutic potential of the interleukin-4/interleukin-13 signaling pathway in asthma. American journal of respiratory medicine : drugs, devices, and other interventions\| PubMed ID: 14720056	2002
Overlapping and independent contributions of MMP2 and MMP9 to lung allergic inflammatory cell egression through decreased CC chemokines. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 15059974	2004
Epidermal detachment, desmosomal dissociation, and destabilization of corneodesmosin in Spink5-/- mice. Genes & development\| PubMed ID: 15466487	2004
An immune basis for lung parenchymal destruction in chronic obstructive pulmonary disease and emphysema. PLoS medicine\| PubMed ID: 15526056	2004
Endogenous attenuation of allergic lung inflammation by syndecan-1. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 15843578	2005
The future of asthma therapy: integrating clinical and experimental studies. Immunologic research\| PubMed ID: 16120971	2005
The role of relaxin in endometrial cancer. Cancer biology & therapy\| PubMed ID: 16322684	2006
7. Control of allergic airway inflammation through immunomodulation. The Journal of allergy and clinical immunology\| PubMed ID: 16455347	2006
Identification of P311 as a potential gene regulating alveolar generation. American journal of respiratory cell and molecular biology\| PubMed ID: 16484684	2006
Asthma: pathology and pathophysiology. Archives of pathology & laboratory medicine\| PubMed ID: 16594736	2006
Proteomic identification of in vivo substrates for matrix metalloproteinases 2 and 9 reveals a mechanism for resolution of inflammation. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 17082650	2006
Matrix metalloproteinases in lung: multiple, multifarious, and multifaceted. Physiological reviews\| PubMed ID: 17237343	2007
Type I collagen is a genetic modifier of matrix metalloproteinase 2 in murine skeletal development. Developmental dynamics : an official publication of the American Association of Anatomists\| PubMed ID: 17440987	2007
Antielastin autoimmunity in tobacco smoking-induced emphysema. Nature medicine\| PubMed ID: 17450149	2007
A new mechanism regulating the initiation of allergic airway inflammation. The Journal of allergy and clinical immunology\| PubMed ID: 17544098	2007
A new link to airway obstruction in asthma. Nature medicine\| PubMed ID: 17618262	2007
Discovery of novel markers in allergic lung inflammation through proteomic-based technologies. Expert review of proteomics\| PubMed ID: 18282117	2008
Developmental control of integrin expression regulates Th2 effector homing. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 18354189	2008
Fungal proteases induce Th2 polarization through limited dendritic cell maturation and reduced production of IL-12. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 18424720	2008
A3 adenosine receptor signaling influences pulmonary inflammation and fibrosis. American journal of respiratory cell and molecular biology\| PubMed ID: 18587054	2008
At last, an immune organ we can call our own? American journal of respiratory and critical care medicine\| PubMed ID: 19326572	2009
Divergent functions for airway epithelial matrix metalloproteinase 7 and retinoic acid in experimental asthma. Nature immunology\| PubMed ID: 19329997	2009
Toward a comprehensive understanding of allergic lung disease. Transactions of the American Clinical and Climatological Association\| PubMed ID: 19768161	2009
Smoking gun: mature dendritic cells in human lung provide clues to chronic obstructive pulmonary disease. American journal of respiratory and critical care medicine\| PubMed ID: 19949238	2009
Lung myeloid dendritic cells coordinately induce TH1 and TH17 responses in human emphysema. Science translational medicine\| PubMed ID: 20368170	2009
Human rhinovirus proteinase 2A induces TH1 and TH2 immunity in patients with chronic obstructive pulmonary disease. The Journal of allergy and clinical immunology\| PubMed ID: 20430426	2010
Proinflammatory role for let-7 microRNAS in experimental asthma. The Journal of biological chemistry\| PubMed ID: 20630862	2010
Endogenous matrix metalloproteinases 2 and 9 regulate activation of CD4+ and CD8+ T cells. American journal of respiratory cell and molecular biology\| PubMed ID: 20639459	2011
Respiratory tract allergic disease and atopy: experimental evidence for a fungal infectious etiology. Medical mycology : official publication of the International Society for Human and Animal Mycology\| PubMed ID: 20807032	2011
Seeking common pathophysiology in asthma, atopy and sinusitis. Trends in immunology\| PubMed ID: 21239229	2011
Dual protective mechanisms of matrix metalloproteinases 2 and 9 in immune defense against Streptococcus pneumoniae. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 21508260	2011
Resting energy expenditure and protein turnover are increased in patients with severe chronic obstructive pulmonary disease. Metabolism: clinical and experimental\| PubMed ID: 21550084	2011
Cross-sectional analysis of the utility of pulmonary function tests in predicting emphysema in ever-smokers. International journal of environmental research and public health\| PubMed ID: 21655122	2011
Proteinases as molecular adjuvants in allergic airway disease. Biochimica et biophysica acta\| PubMed ID: 21712069	2011
Necessary and sufficient role for T helper cells to prevent fungal dissemination in allergic lung disease. Infection and immunity\| PubMed ID: 21875960	2011
ATXN1 protein family and CIC regulate extracellular matrix remodeling and lung alveolarization. Developmental cell\| PubMed ID: 22014525	2011
Glucose and pyruvate metabolism in severe chronic obstructive pulmonary disease. Journal of applied physiology (Bethesda, Md. : 1985)\| PubMed ID: 22016370	2012
Cigarette Smoke Induction of Osteopontin (SPP1) Mediates TH17 Inflammation in Human and Experimental Emphysema. Science translational medicine\| PubMed ID: 22261033	2012
Autoimmunity in chronic obstructive pulmonary disease: clinical and experimental evidence. Expert review of clinical immunology\| PubMed ID: 22390492	2012
Autoreactive T Cells in Human Smokers is Predictive of Clinical Outcome. Frontiers in immunology\| PubMed ID: 22969766	2012
Overexpression of methyl-CpG binding protein 2 impairs T(H)1 responses. Science translational medicine\| PubMed ID: 23220634	2012
Tracheobronchial mycosis in a retrospective case-series study of five status asthmaticus patients. Clinical immunology (Orlando, Fla.)\| PubMed ID: 23280490	2013
CD11a polymorphisms regulate TH2 cell homing and TH2-related disease. The Journal of allergy and clinical immunology\| PubMed ID: 23726040	2014
IL-33-responsive innate lymphoid cells are an important source of IL-13 in chronic rhinosinusitis with nasal polyps. American journal of respiratory and critical care medicine\| PubMed ID: 23805875	2013
Cleavage of fibrinogen by proteinases elicits allergic responses through Toll-like receptor 4. Science (New York, N.Y.)\| PubMed ID: 23950537	2013
Agonistic induction of PPARγ reverses cigarette smoke-induced emphysema. The Journal of clinical investigation\| PubMed ID: 24569375	2014
Essential role for autophagy in the maintenance of immunological memory against influenza infection. Nature medicine\| PubMed ID: 24747745	2014
Airway surface mycosis in chronic TH2-associated airway disease. The Journal of allergy and clinical immunology\| PubMed ID: 24928648	2014
Leukotriene A4 hydrolase: the Janus enzyme shows its ugly side in smokers. American journal of respiratory and critical care medicine\| PubMed ID: 24983216	2014
Activation of C3a receptor is required in cigarette smoke-mediated emphysema. Mucosal immunology\| PubMed ID: 25465103	2015
Airway fibrinogenolysis and the initiation of allergic inflammation. Annals of the American Thoracic Society\| PubMed ID: 25525732	2014
Randomized trial of endobronchial ultrasound-guided transbronchial needle aspiration under general anesthesia versus moderate sedation. American journal of respiratory and critical care medicine\| PubMed ID: 25574801	2015
Bioactive lipids in emphysema. Decoding fat to reveal COPD phenotypes. American journal of respiratory and critical care medicine\| PubMed ID: 25635483	2015
ErbB2 Pathway Activation upon Smad4 Loss Promotes Lung Tumor Growth and Metastasis. Cell reports\| PubMed ID: 25753424	2015
Reply: Is Endobronchial Ultrasound Influenced by Sedation Strategy? Comparing Apples to Apples. American journal of respiratory and critical care medicine\| PubMed ID: 26075429	2015
Clinical and Immunological Factors in Emphysema Progression. Five-Year Prospective Longitudinal Exacerbation Study of Chronic Obstructive Pulmonary Disease (LES-COPD). American journal of respiratory and critical care medicine\| PubMed ID: 26241705	2015
The microRNA miR-22 inhibits the histone deacetylase HDAC4 to promote T(H)17 cell-dependent emphysema. Nature immunology\| PubMed ID: 26437241	2015
Nanoparticulate carbon black in cigarette smoke induces DNA cleavage and Th17-mediated emphysema. eLife\| PubMed ID: 26437452	2015
Loss of Peripheral Tolerance in Emphysema. Phenotypes, Exacerbations, and Disease Progression. Annals of the American Thoracic Society\| PubMed ID: 26595734	2015
Long-Acting Beta Agonists Enhance Allergic Airway Disease. PloS one\| PubMed ID: 26605551	2015
Allergen-encoded signals that control allergic responses. Current opinion in allergy and clinical immunology\| PubMed ID: 26658015	2016
Focused Analysis of Exome Sequencing Data for Rare Germline Mutations in Familial and Sporadic Lung Cancer. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer\| PubMed ID: 26762739	2016
Progression of EGFR-Mutant Lung Adenocarcinoma is Driven By Alveolar Macrophages. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 27496865	2017
The Role of Matrix Metalloproteinases in Development, Repair, and Destruction of the Lungs. Progress in molecular biology and translational science\| PubMed ID: 28662821	2017
Cigarette Smoke and DNA Cleavage Promote Lung Inflammation and Emphysema. Transactions of the American Clinical and Climatological Association\| PubMed ID: 28790504	2017
Cancer Immunotherapy: Historical Perspective of a Clinical Revolution and Emerging Preclinical Animal Models. Frontiers in immunology\| PubMed ID: 28824608	2017
Tobacco-Specific Carcinogens Induce Hypermethylation, DNA Adducts, and DNA Damage in Bladder Cancer. Cancer prevention research (Philadelphia, Pa.)\| PubMed ID: 28851690	2017
Th17/Treg immunoregulation and implications in treatment of sulfur mustard gas-induced lung diseases. Expert review of clinical immunology\| PubMed ID: 28994328	2017
Fibrinogen cleavage products and Toll-like receptor 4 promote the generation of programmed cell death 1 ligand 2-positive dendritic cells in allergic asthma. The Journal of allergy and clinical immunology\| PubMed ID: 29038008	2018
AIMp1 Potentiates T1 Polarization and Is Critical for Effective Antitumor and Antiviral Immunity. Frontiers in immunology\| PubMed ID: 29379495	2017
Advances and Evolving Concepts in Allergic Asthma. Seminars in respiratory and critical care medicine\| PubMed ID: 29427987	2018
Extracellular matrix in lung development, homeostasis and disease. Matrix biology : journal of the International Society for Matrix Biology\| PubMed ID: 29524630	2018
Matrix remodeling in chronic lung diseases. Matrix biology : journal of the International Society for Matrix Biology\| PubMed ID: 29559389	2018
Benefits of antifungal therapy in asthma patients with airway mycosis: A retrospective cohort analysis. Immunity, inflammation and disease\| PubMed ID: 29575717	2018
Comprehensive immunoproteogenomic analyses of malignant pleural mesothelioma. JCI insight\| PubMed ID: 29618661	2018
IL17A Regulates Tumor Latency and Metastasis in Lung Adeno and Squamous SQ.2b and AD.1 Cancer. Cancer immunology research\| PubMed ID: 29653981	2018
A Fungal Protease Model to Interrogate Allergic Lung Immunity. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 29956139	2018
Rare Variants in Known Susceptibility Loci and Their Contribution to Risk of Lung Cancer. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer\| PubMed ID: 29981437	2018
Lung tissue microbial profile in lung cancer is distinct from emphysema. American journal of cancer research\| PubMed ID: 30323970	2018
Fungi in Mucoobstructive Airway Diseases. Annals of the American Thoracic Society\| PubMed ID: 30431347	2018
Laryngeal inflammatory response to smoke and vape in a murine model. American journal of otolaryngology\| PubMed ID: 30472132	2019
Microglia and amyloid precursor protein coordinate control of transient Candida cerebritis with memory deficits. Nature communications\| PubMed ID: 30610193	2019
Cigarette Smoke Induces Intestinal Inflammation via a Th17 Cell-Neutrophil Axis. Frontiers in immunology\| PubMed ID: 30761142	2019
Elastin-Specific Autoimmunity in Smokers With Thoracic Aortic Aneurysm and Dissection is Independent of Chronic Obstructive Pulmonary Disease. Journal of the American Heart Association\| PubMed ID: 30957625	2019
Selective cleavage of fibrinogen by diverse proteinases initiates innate allergic and antifungal immunity through CD11b. The Journal of biological chemistry\| PubMed ID: 30992366	2019
Taming Peptides with Peptides: Neutralizing Proline-Glycine-Proline with l-Arginine-Threonine-Arginine to Treat Cigarette Smoke-induced Emphysema. American journal of respiratory cell and molecular biology\| PubMed ID: 31046397	2019
Cigarette smoke-induced reduction of C1q promotes emphysema. JCI insight\| PubMed ID: 31112138	2019
A Novel Animal Model of Emphysema Induced by Anti-Elastin Autoimmunity. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 31182478	2019
Airway mycosis in allergic airway disease. Advances in immunology\| PubMed ID: 31296304	2019
Electronic cigarettes disrupt lung lipid homeostasis and innate immunity independent of nicotine. The Journal of clinical investigation\| PubMed ID: 31483291	2019
Lung Cancer Heterogeneity in Modulation of Th17/IL17A Responses. Frontiers in oncology\| PubMed ID: 31921642	2019
Comprehensive T cell repertoire characterization of non-small cell lung cancer. Nature communications\| PubMed ID: 32001676	2020
E-Cigarette or Vaping Product Use-associated Lung Injury: Developing a Research Agenda. An NIH Workshop Report. American journal of respiratory and critical care medicine\| PubMed ID: 32243764	2020
Tobacco Smoking Increases the Lung Gene Expression of ACE2, the Receptor of SARS-CoV-2. American journal of respiratory and critical care medicine\| PubMed ID: 32329629	2020
Airway Mycosis and the Regulation of Type 2 Immunity. Journal of fungi (Basel, Switzerland)\| PubMed ID: 32485866	2020
A global Slc7a7 knockout mouse model demonstrates characteristic phenotypes of human lysinuric protein intolerance. Human molecular genetics\| PubMed ID: 32504080	2020
Reply to Polverino: Cigarette Smoking and COVID-19: A Complex Interaction. American journal of respiratory and critical care medicine\| PubMed ID: 32530707	2020