Michael R. Emmert-Buck

Laboratory of Pathology, National Institutes of Health

Affiliated withNational Institutes of Health

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 6	2014

Other Publications

Article	Year
Determination of a minimal deletion interval on chromosome band 8p21 in sporadic prostate cancer. Genes, chromosomes & cancer\| PubMed ID: 11793446	2002
Proteomic analysis of human prostate cancer. Molecular carcinogenesis\| PubMed ID: 11807953	2002
Evaluation of non-formalin tissue fixation for molecular profiling studies. The American journal of pathology\| PubMed ID: 11839565	2002
Loss of heterozygosity on chromosome arms 3p and 6q in microdissected adenocarcinomas of the uterine cervix and adenocarcinoma in situ. Cancer\| PubMed ID: 11857315	2002
Infrequent mutation in the BRCA2 gene in esophageal squamous cell carcinoma. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 11948123	2002
The RASSF1A tumor suppressor gene is inactivated in prostate tumors and suppresses growth of prostate carcinoma cells. Cancer research\| PubMed ID: 12067994	2002
2D differential in-gel electrophoresis for the identification of esophageal scans cell cancer-specific protein markers. Molecular & cellular proteomics : MCP\| PubMed ID: 12096129	2002
Alterations in gene expression profiles during prostate cancer progression: functional correlations to tumorigenicity and down-regulation of selenoprotein-P in mouse and human tumors. Cancer research\| PubMed ID: 12235003	2002
Serum proteomic patterns for detection of prostate cancer. Journal of the National Cancer Institute\| PubMed ID: 12381711	2002
Post-analysis follow-up and validation of microarray experiments. Nature genetics\| PubMed ID: 12454646	2002
Allelic loss on chromosome 13q14 and mutation in deleted in cancer 1 gene in esophageal squamous cell carcinoma. Oncogene\| PubMed ID: 12527901	2003
The granulin-epithelin precursor/PC-cell-derived growth factor is a growth factor for epithelial ovarian cancer. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 12538450	2003
Evaluation of ethanol-fixed, paraffin-embedded tissues for proteomic applications. Proteomics\| PubMed ID: 12687609	2003
Approaches to proteomic analysis of human tumors. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 12710699	2003
Molecular differentiation of high- and moderate-grade human prostate cancer by cDNA microarray analysis. Diagnostic molecular pathology : the American journal of surgical pathology, part B\| PubMed ID: 12766610	2003
Handling of clinical tissue specimens for molecular profiling studies. Current issues in molecular biology\| PubMed ID: 12793526	2003
Gene expression analysis of esophageal squamous cell carcinoma reveals consistent molecular profiles related to a family history of upper gastrointestinal cancer. Cancer research\| PubMed ID: 12873975	2003
Mitochondrial proteome: altered cytochrome c oxidase subunit levels in prostate cancer. Proteomics\| PubMed ID: 12973739	2003
Evidence for a familial esophageal cancer susceptibility gene on chromosome 13. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology\| PubMed ID: 14578153	2003
Parathyroid gland-specific deletion of the mouse Men1 gene results in parathyroid neoplasia and hypercalcemic hyperparathyroidism. Cancer research\| PubMed ID: 14633735	2003
Evaluation of BRCA2 in the genetic susceptibility of familial esophageal cancer. Oncogene\| PubMed ID: 14647438	2004
Layered expression scanning: multiplex analysis of RNA and protein gels. BioTechniques\| PubMed ID: 14682064	2003
High frequency of CDKN2A alterations in esophageal squamous cell carcinoma from a high-risk Chinese population. Genes, chromosomes & cancer\| PubMed ID: 14732922	2004
Molecular profiling of cancer. Toxicologic pathology\| PubMed ID: 15209405	2004
Multimembrane dot-blotting: a cost-effective tool for proteome analysis. BioTechniques\| PubMed ID: 15211757	2004
Comprehensive characterization of annexin I alterations in esophageal squamous cell carcinoma. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 15447985	2004
Comparison of snap freezing versus ethanol fixation for gene expression profiling of tissue specimens. The Journal of molecular diagnostics : JMD\| PubMed ID: 15507677	2004
Expression microdissection: operator-independent retrieval of cells for molecular profiling. Diagnostic molecular pathology : the American journal of surgical pathology, part B\| PubMed ID: 15538110	2004
Optimal molecular profiling of tissue and tissue components: defining the best processing and microdissection methods for biomedical applications. Methods in molecular medicine\| PubMed ID: 15542897	2005
Histomathematical analysis of clinical specimens: challenges and progress. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society\| PubMed ID: 15684330	2005
Optimal molecular profiling of tissue and tissue components: defining the best processing and microdissection methods for biomedical applications. Molecular biotechnology\| PubMed ID: 15699569	2005
Genome-wide association study in esophageal cancer using GeneChip mapping 10K array. Cancer research\| PubMed ID: 15805246	2005
Profiling EGFR activity in head and neck squamous cell carcinoma by using a novel layered membrane Western blot technology. Oral oncology\| PubMed ID: 15878755	2005
Novel proteomic approaches for tissue analysis. Expert review of proteomics\| PubMed ID: 15966813	2004
Allelotyping of esophageal squamous-cell carcinoma on chromosome 13 defines deletions related to family history. Genes, chromosomes & cancer\| PubMed ID: 16015646	2005
Molecular alterations in primary prostate cancer after androgen ablation therapy. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 16203770	2005
Layered peptide arrays: high-throughput antibody screening of clinical samples. The Journal of molecular diagnostics : JMD\| PubMed ID: 16237212	2005
Gene promoter methylation in prostate tumor-associated stromal cells. Journal of the National Cancer Institute\| PubMed ID: 16478744	2006
Tumor-associated endothelial cells display GSTP1 and RARbeta2 promoter methylation in human prostate cancer. Journal of translational medicine\| PubMed ID: 16512911	2006
Layered expression scanning: multiplex molecular analysis of diverse life science platforms. Clinica chimica acta; international journal of clinical chemistry\| PubMed ID: 16996046	2007
Genome-wide loss of heterozygosity and copy number alteration in esophageal squamous cell carcinoma using the Affymetrix GeneChip Mapping 10 K array. BMC genomics\| PubMed ID: 17134496	2006
Increased expression of VEGF121/VEGF165-189 ratio results in a significant enhancement of human prostate tumor angiogenesis. International journal of cancer. Journal international du cancer\| PubMed ID: 17278099	2007
Layered peptide arrays: a diverse technique for antibody screening of clinical samples. Annals of the New York Academy of Sciences\| PubMed ID: 17435150	2007
Layered peptide array for multiplex immunohistochemistry. The Journal of molecular diagnostics : JMD\| PubMed ID: 17591928	2007
Assessment of normalization strategies for quantitative RT-PCR using microdissected tissue samples. Laboratory investigation; a journal of technical methods and pathology\| PubMed ID: 17643124	2007
Global expression analysis of prostate cancer-associated stroma and epithelia. Diagnostic molecular pathology : the American journal of surgical pathology, part B\| PubMed ID: 18043281	2007
Quantitation of HER2 and telomerase biomarkers in solid tumors with IgY antibodies and nanocrystal detection. International journal of cancer. Journal international du cancer\| PubMed ID: 18214859	2008
Tissue microdissection. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 18369881	2008
Overexpression of CDC25B and LAMC2 mRNA and protein in esophageal squamous cell carcinomas and premalignant lesions in subjects from a high-risk population in China. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology\| PubMed ID: 18559558	2008
Quantitation of steroid hormones in thin fresh frozen tissue sections. Analytical chemistry\| PubMed ID: 18937426	2008
Large-scale profiling of archival lymph nodes reveals pervasive remodeling of the follicular lymphoma methylome. Cancer research\| PubMed ID: 19155300	2009
Quantitative RT-PCR gene expression analysis of laser microdissected tissue samples. Nature protocols\| PubMed ID: 19478806	2009
Current molecular diagnostics of breast cancer and the potential incorporation of microRNA. Expert review of molecular diagnostics\| PubMed ID: 19580430	2009
Identification of EpCAM as a molecular target of prostate cancer stroma. The American journal of pathology\| PubMed ID: 19850885	2009
High throughput screening of normal and neoplastic tissue samples. Combinatorial chemistry & high throughput screening\| PubMed ID: 20015016	2010
2D-PCR: a method of mapping DNA in tissue sections. Lab on a chip\| PubMed ID: 20024032	2009
Immunoguided laser assisted microdissection techniques for DNA methylation analysis of archival tissue specimens. The Journal of molecular diagnostics : JMD\| PubMed ID: 20413681	2010
Influence of hypoxia induced by minimally invasive prostatectomy on gene expression: implications for biomarker analysis. American journal of translational research\| PubMed ID: 20589162	2010
Proteomic profiling of cancer--opportunities, challenges, and context. The Journal of pathology\| PubMed ID: 20623483	2010
Increased matrix metalloproteinase activation in esophageal squamous cell carcinoma. Journal of translational medicine\| PubMed ID: 20920372	2010
Layered electrophoretic transfer - A method for pre-analytic processing of histological sections. Proteomics\| PubMed ID: 21280224	2011
Expression microdissection adapted to commercial laser dissection instruments. Nature protocols\| PubMed ID: 21412274	2011
Effect of immunohistochemistry on molecular analysis of tissue samples: implications for microdissection technologies. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society\| PubMed ID: 21430260	2011
Methylation profiling of mediastinal gray zone lymphoma reveals a distinctive signature with elements shared by classical Hodgkin's lymphoma and primary mediastinal large B-cell lymphoma. Haematologica\| PubMed ID: 21454882	2011
An NIH intramural percubator as a model of academic-industry partnerships: from the beginning of life through the valley of death. Journal of translational medicine\| PubMed ID: 21548992	2011
Digital slide repositories for publications: lessons learned from the microarray community. The American journal of surgical pathology\| PubMed ID: 21552111	2011
Quantifying mRNA levels across tissue sections with 2D-RT-qPCR. Analytical and bioanalytical chemistry\| PubMed ID: 21559756	2011
SIVQ-aided laser capture microdissection: A tool for high-throughput expression profiling. Journal of pathology informatics\| PubMed ID: 21572509	2011
Why is it crucial to reintegrate pathology into cancer research? BioEssays : news and reviews in molecular, cellular and developmental biology\| PubMed ID: 21590787	2011
Immunoguided microdissection techniques. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 21761293	2011
MicroRNA analysis of microdissected normal squamous esophageal epithelium and tumor cells. American journal of cancer research\| PubMed ID: 21796275	2011
Squamous Cell Carcinoma - Similarities and Differences among Anatomical Sites. American journal of cancer research\| PubMed ID: 21938273	2011
Decrease in CD8+ lymphocyte number and altered cytokine profile in human prostate cancer. American journal of cancer research\| PubMed ID: 21969236	2011
Launching of American Journal of Cancer Research. American journal of cancer research\| PubMed ID: 21969259	2011
American journal of cancer research: editorial board (2011). American journal of cancer research\| PubMed ID: 22016829	2011
A dynamic magnetic shift method to increase nanoparticle concentration in cancer metastases: a feasibility study using simulations on autopsy specimens. International journal of nanomedicine\| PubMed ID: 22131836	2011
Image microarrays (IMA): Digital pathology's missing tool. Journal of pathology informatics\| PubMed ID: 22200030	2011
Identification of unique expression signatures and therapeutic targets in esophageal squamous cell carcinoma. BMC research notes\| PubMed ID: 22280838	2012
Integration of architectural and cytologic driven image algorithms for prostate adenocarcinoma identification. Analytical cellular pathology (Amsterdam)\| PubMed ID: 22425661	2012
Semiautomated laser capture microdissection of lung adenocarcinoma cytology samples. Acta cytologica\| PubMed ID: 23207440	2012
Three-dimensional mRNA measurements reveal minimal regional heterogeneity in esophageal squamous cell carcinoma. The American journal of pathology\| PubMed ID: 23219752	2013
Optimal molecular profiling of tissue and tissue components: defining the best processing and microdissection methods for biomedical applications. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 23359150	2013
Proteomic analysis of frozen tissue samples using laser capture microdissection. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 23625395	2013
Measuring collective cell movement and extracellular matrix interactions using magnetic resonance imaging. Scientific reports\| PubMed ID: 23698816	2013
Analysis of transcription factor mRNAs in identified oxytocin and vasopressin magnocellular neurons isolated by laser capture microdissection. PloS one\| PubMed ID: 23894472	2013
Validation of esophageal squamous cell carcinoma candidate genes from high-throughput transcriptomic studies. American journal of cancer research\| PubMed ID: 23977449	2013
Deletion of the olfactomedin 4 gene is associated with progression of human prostate cancer. The American journal of pathology\| PubMed ID: 24070418	2013
Multiplex quantitative measurement of mRNAs from fixed tissue microarray sections. Applied immunohistochemistry & molecular morphology : AIMM / official publication of the Society for Applied Immunohistochemistry\| PubMed ID: 24809843	2014