Sharon C. A. Chen

Centre for Infectious Diseases and Microbiology Laboratory Services, Westmead hospital

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 1	2014

Other Publications

Article	Year
Cryptococcosis in Australasia and the treatment of cryptococcal and other fungal infections with liposomal amphotericin B. The Journal of antimicrobial chemotherapy\| PubMed ID: 11801583	2002
Strain-dependent effects of environmental signals on the production of extracellular phospholipase by Cryptococcus neoformans. FEMS microbiology letters\| PubMed ID: 12007802	2002
A review of nucleic acid-based diagnostic tests for systemic mycoses with an emphasis on polymerase chain reaction-based assays. Medical mycology\| PubMed ID: 12230214	2002
Cryptococcal phospholipases: a novel lysophospholipase discovered in the pathogenic fungus Cryptococcus gattii. The Biochemical journal\| PubMed ID: 15320865	2004
Disseminated Mycobacterium avium infection in young cats: overrepresentation of Abyssinian cats. Journal of feline medicine and surgery\| PubMed ID: 16226469	2006
Community-acquired methicillin-resistant Staphylococcus aureus: time for action. Pathology\| PubMed ID: 16753738	2006
Successful treatment of a localised CDC Group EF-4a infection in a cat. Journal of feline medicine and surgery\| PubMed ID: 16934513	2007
Cryptococcal phospholipase B antigen is not detected in serum of patients infected with Cryptococcus neoformans using a sandwich enzyme-linked immunosorbent assay. FEMS yeast research\| PubMed ID: 17266733	2007
In vitro activities of miltefosine and two novel antifungal biscationic salts against a panel of 77 dermatophytes. Antimicrobial agents and chemotherapy\| PubMed ID: 17371821	2007
Antifungal agents. The Medical journal of Australia\| PubMed ID: 17908006	2007
Treatment of scedosporiosis with voriconazole: clinical experience with 107 patients. Antimicrobial agents and chemotherapy\| PubMed ID: 18212110	2008
Molecular typing of Australian Scedosporium isolates showing genetic variability and numerous S. aurantiacum. Emerging infectious diseases\| PubMed ID: 18258122	2008
Practical method for detection and identification of Candida, Aspergillus, and Scedosporium spp. by use of rolling-circle amplification. Journal of clinical microbiology\| PubMed ID: 18495860	2008
Genotyping of Scedosporium species: a review of molecular approaches. Medical mycology\| PubMed ID: 19085455	2009
Not just little adults: candidemia epidemiology, molecular characterization, and antifungal susceptibility in neonatal and pediatric patients. Pediatrics\| PubMed ID: 19403503	2009
Assignment of Reference 5'-end 16S rDNA Sequences and Species-Specific Sequence Polymorphisms Improves Species Identification of Nocardia. The open microbiology journal\| PubMed ID: 19639036	2009
Molecular epidemiology of invasive aspergillosis: lessons learned from an outbreak investigation in an Australian hematology unit. Infection control and hospital epidemiology : the official journal of the Society of Hospital Epidemiologists of America\| PubMed ID: 19848605	2009
Diagnostic and typing methods for investigating Legionella infection. New South Wales public health bulletin\| PubMed ID: 19917208	2009
Identification of pathogenic Nocardia species by reverse line blot hybridization targeting the 16S rRNA and 16S-23S rRNA gene spacer regions. Journal of clinical microbiology\| PubMed ID: 19955277	2010
Comparison of whole blood, serum, and plasma for early detection of candidemia by multiplex-tandem PCR. Journal of clinical microbiology\| PubMed ID: 20042634	2010
Fungal-derived immune modulating molecules. Advances in experimental medicine and biology\| PubMed ID: 20054979	2009
Protein-losing enteropathy and hypogammaglobulinaemia as first manifestations of disseminated histoplasmosis coincident with Nocardia infection. Journal of medical microbiology\| PubMed ID: 20133412	2010
Candidaemia in adult cancer patients: risks for fluconazole-resistant isolates and death. The Journal of antimicrobial chemotherapy\| PubMed ID: 20202987	2010
In vitro antifungal activities of bis(alkylpyridinium)alkane compounds against pathogenic yeasts and molds. Antimicrobial agents and chemotherapy\| PubMed ID: 20530227	2010
Antifungal therapy in invasive fungal infections. Current opinion in pharmacology\| PubMed ID: 20598943	2010
secA1 gene sequence polymorphisms for species identification of Nocardia species and recognition of intraspecies genetic diversity. Journal of clinical microbiology\| PubMed ID: 20810768	2010
New molecular and surrogate biomarker-based tests in the diagnosis of bacterial and fungal infection in febrile neutropenic patients. Current opinion in infectious diseases\| PubMed ID: 20827189	2010
Clinical associations and prevalence of Scedosporium spp. in Australian cystic fibrosis patients: identification of novel risk factors? Medical mycology\| PubMed ID: 21067328	2010
Scedosporium aurantiacum is as virulent as S. prolificans, and shows strain-specific virulence differences, in a mouse model. Medical mycology\| PubMed ID: 21067330	2010
Abundance of Pseudallescheria/Scedosporium species in the Australian urban environment suggests a possible source for scedosporiosis including the colonization of airways in cystic fibrosis. Medical mycology\| PubMed ID: 21067333	2010
Recent advances in management of cryptococcal meningitis: commentary. F1000 medicine reports\| PubMed ID: 21170376	2010
Echinocandin antifungal drugs in fungal infections: a comparison. Drugs\| PubMed ID: 21175238	2011
Design issues in a randomized controlled trial of a pre-emptive versus empiric antifungal strategy for invasive aspergillosis in patients with high-risk hematologic malignancies. Leukemia & lymphoma\| PubMed ID: 21281234	2011
Development and validation of a multiplex PCR for detection of Scedosporium spp. in respiratory tract specimens from patients with cystic fibrosis. Journal of clinical microbiology\| PubMed ID: 21325557	2011
Nocardia infections of the face and neck. Current infectious disease reports\| PubMed ID: 21365376	2011
Fatal mycotic aneurysms due to Scedosporium and Pseudallescheria infection. Journal of clinical microbiology\| PubMed ID: 21430108	2011
Cost-effectiveness analysis of anidulafungin versus fluconazole for the treatment of invasive candidiasis. The Journal of antimicrobial chemotherapy\| PubMed ID: 21628305	2011
Defining reference sequences for Nocardia species by similarity and clustering analyses of 16S rRNA gene sequence data. PloS one\| PubMed ID: 21687706	2011
Direct effects of non-antifungal agents used in cancer chemotherapy and organ transplantation on the development and virulence of Candida and Aspergillus species. Virulence\| PubMed ID: 21701255	2011
Identification of bacteria in blood culture broths using matrix-assisted laser desorption-ionization Sepsityper™ and time of flight mass spectrometry. PloS one\| PubMed ID: 21858058	2011
Three-locus identification, genotyping, and antifungal susceptibilities of medically important Trichosporon species from China. Journal of clinical microbiology\| PubMed ID: 21900517	2011
Pneumocystis jirovecii pneumonia in non-HIV-infected patients: new risks and diagnostic tools. Current opinion in infectious diseases\| PubMed ID: 21986616	2011
Matrix-assisted laser desorption ionization-time of flight mass spectrometry identification of yeasts is contingent on robust reference spectra. PloS one\| PubMed ID: 22022438	2011
Nosocomial Pneumocystis jirovecii pneumonia: lessons from a cluster in kidney transplant recipients. Transplantation\| PubMed ID: 22129760	2011
Seeking clarity within cloudy effluents: differentiating fungal from bacterial peritonitis in peritoneal dialysis patients. PloS one\| PubMed ID: 22145033	2011
Pneumonia and lung infections due to emerging and unusual fungal pathogens. Seminars in respiratory and critical care medicine\| PubMed ID: 22167398	2011
Sporotrichosis (Sporothrix schenckii infection) in the New South Wales mid-north coast, 2000-2010. The Medical journal of Australia\| PubMed ID: 22621152	2012
Hospital costs, length of stay and mortality attributable to invasive scedosporiosis in haematology patients. The Journal of antimicrobial chemotherapy\| PubMed ID: 22643193	2012
Clinical manifestations of Cryptococcus gattii infection: determinants of neurological sequelae and death. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America\| PubMed ID: 22670042	2012
Coccidioidal septic arthritis: lessons learned from a clinical and laboratory perspective. The Medical journal of Australia\| PubMed ID: 22708769	2012
Multicenter study of voriconazole pharmacokinetics and therapeutic drug monitoring. Antimicrobial agents and chemotherapy\| PubMed ID: 22751544	2012
Multicenter study of posaconazole therapeutic drug monitoring: exposure-response relationship and factors affecting concentration. Antimicrobial agents and chemotherapy\| PubMed ID: 22890761	2012
In vitro susceptibilities of yeast species to fluconazole and voriconazole as determined by the 2010 National China Hospital Invasive Fungal Surveillance Net (CHIF-NET) study. Journal of clinical microbiology\| PubMed ID: 23035204	2012
Cryptococcosis, lymphoproliferative disorders and modern day chemotherapy regimens. Leukemia & lymphoma\| PubMed ID: 23035788	2013
Clinical utility of the cryptococcal antigen lateral flow assay in a diagnostic mycology laboratory. PloS one\| PubMed ID: 23166705	2012
Practical identification of eight medically important Trichosporon species by reverse line blot hybridization (RLB) assay and rolling circle amplification (RCA). Medical mycology\| PubMed ID: 23186014	2013
Current status of matrix-assisted laser desorption ionisation-time of flight mass spectrometry in the clinical microbiology laboratory. Pathology\| PubMed ID: 23255029	2013
Generalized subcutaneous phaeohyphomycosis caused by Phialophora verrucosa: report of a case and review of literature. Mycopathologia\| PubMed ID: 23392822	2013
Economic evaluation of micafungin vs. liposomal amphotericin B (LAmB) for the treatment of candidaemia and invasive candidiasis (IC). Mycoses\| PubMed ID: 23496163	2013
Pharmacoeconomics of empirical antifungal use in febrile neutropenic hematological malignancy and hematopoietic stem cell transplant patients. Expert review of pharmacoeconomics & outcomes research\| PubMed ID: 23570433	2013
Galactomannan and PCR versus culture and histology for directing use of antifungal treatment for invasive aspergillosis in high-risk haematology patients: a randomised controlled trial. The Lancet infectious diseases\| PubMed ID: 23639612	2013
Antifungal therapy and management of complications of cryptococcosis due to Cryptococcus gattii. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America\| PubMed ID: 23697747	2013
Post-transplant Pneumocystis jirovecii pneumonia-a re-emerged public health problem? Kidney international\| PubMed ID: 23739237	2013
Molecular epidemiology linking multihospital clusters of opportunistic Pneumocystis jirovecii pneumonia. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America\| PubMed ID: 23794722	2013
Utility of bronchoalveolar lavage fluid galactomannan alone or in combination with PCR for the diagnosis of invasive aspergillosis in adult hematology patients: A systematic review and meta-... Critical reviews in microbiology\| PubMed ID: 23799871	2013
In vitro activity of miltefosine as a single agent and in combination with voriconazole or posaconazole against uncommon filamentous fungal pathogens. The Journal of antimicrobial chemotherapy\| PubMed ID: 23861311	2013
Rapid identification of Gram-negative organisms from blood culture bottles using a modified extraction method and MALDI-TOF mass spectrometry. Diagnostic microbiology and infectious disease\| PubMed ID: 23891220	2013
Fungal infections and treatment in cystic fibrosis. Current opinion in pulmonary medicine\| PubMed ID: 24060984	2013
Functional characterization of the hexose transporter Hxt13p: an efflux pump that mediates resistance to miltefosine in yeast. Fungal genetics and biology : FG & B\| PubMed ID: 24076076	2013
A loop-mediated isothermal amplification (LAMP) assay for Strongyloides stercoralis in stool that uses a visual detection method with SYTO-82 fluorescent dye. The American journal of tropical medicine and hygiene\| PubMed ID: 24323513	2014
Thermomyces lanuginosus infective endocarditis: Case report and a review of endocarditis due to uncommon moulds. Medical mycology case reports\| PubMed ID: 24432243	2013
Anti-granulocyte-macrophage colony-stimulating factor autoantibodies are a risk factor for central nervous system infection by Cryptococcus gattii in otherwise immunocompetent patients. mBio\| PubMed ID: 24643864	2014
Echinocandins in the treatment of candidaemia and invasive candidiasis: clinical and economic perspectives. International journal of antimicrobial agents\| PubMed ID: 24670423	2014
Candida quercitrusa candidemia: investigation of three clustered cases and mycological characteristics of this novel species. Journal of clinical microbiology\| PubMed ID: 24696025	2014
Functional disruption of yeast metacaspase, Mca1, leads to miltefosine resistance and inability to mediate miltefosine-induced apoptotic effects. Fungal genetics and biology : FG & B\| PubMed ID: 24731805	2014
Clinical utility of Aspergillus galactomannan and PCR in bronchoalveolar lavage fluid for the diagnosis of invasive pulmonary aspergillosis in patients with haematological malignancies. Diagnostic microbiology and infectious disease\| PubMed ID: 24768294	2014