Takashi Sakurai

Max-Planck-Institute for Molecular Biomedicine and Institute of Cell Biology

Affiliated withMax-Planck-Institute for Molecular Biomedicine and Institute of Cell Biology Yale Cardiovascular Research Center and Section of Cardiovascular Medicine

Research Area

Biology

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 12	2014

Other Publications

Article	Year
The decrease of the cytoskeleton tubulin follows the decrease of the associating molecular chaperone alphaB-crystallin in unloaded soleus muscle atrophy without stretch. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 15894563	2005
Association between perceived social support and Th1 dominance. Biological psychology\| PubMed ID: 15979778	2005
Mononuclear five-coordinate molybdenum(IV) and -(V) monosulfide complexes coordinated with dithiolene ligands: reversible redox of Mo(V)/Mo(IV) and irreversible dimerization of [MoVS]- cores... Inorganic chemistry\| PubMed ID: 16180851	2005
Ray tracing analysis of overlapping objects in refraction contrast imaging. Radiation medicine\| PubMed ID: 16342913	2005
Chromogranin-mediated secretion of mutant superoxide dismutase proteins linked to amyotrophic lateral sclerosis. Nature neuroscience\| PubMed ID: 16369483	2006
[Cognitive dysfunction and dementia associated with elderly diabetes]. Nihon rinsho. Japanese journal of clinical medicine\| PubMed ID: 16408458	2006
Neuroprotective effect of D-fructose-1,6-bisphosphate against beta-amyloid induced neurotoxicity in rat hippocampal organotypic slice culture: involvement of PLC and MEK/ERK signaling pathwa... The Kobe journal of medical sciences\| PubMed ID: 16501318	2005
Cognitive dysfunction associates with white matter hyperintensities and subcortical atrophy on magnetic resonance imaging of the elderly diabetes mellitus Japanese elderly diabetes intervent... Diabetes/metabolism research and reviews\| PubMed ID: 16506272	2006
Impaired response of perforating arteries to hypercapnia in chronic hyperglycemia. The Kobe journal of medical sciences\| PubMed ID: 16609273	2006
Reversible sulfurization-desulfurization of tungsten bis(dithiolene) complexes. Angewandte Chemie (International ed. in English)\| PubMed ID: 16634103	2006
In vivo X-ray angiography in the mouse brain using synchrotron radiation. Stroke; a journal of cerebral circulation\| PubMed ID: 16741182	2006
Association between diastolic blood pressure and lower hemoglobin A1C and frontal brain atrophy in elderly subjects with diabetes mellitus. Journal of the American Geriatrics Society\| PubMed ID: 16776802	2006
Sodium channel beta4 subunit: down-regulation and possible involvement in neuritic degeneration in Huntington's disease transgenic mice. Journal of neurochemistry\| PubMed ID: 16805843	2006
[Expected role of professional geriatric physicians in education for geriatric medicine]. Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics\| PubMed ID: 16937927	2006
Quantification of distension in rat cerebral perforating arteries. Neuroreport\| PubMed ID: 16957606	2006
Carotid artery occlusion and collateral circulation in C57Black/6J mice detected by synchrotron radiation microangiography. The Kobe journal of medical sciences\| PubMed ID: 17006051	2006
The molecular chaperone HSP47 rapidly senses gravitational changes in myoblasts. Genes to cells : devoted to molecular & cellular mechanisms\| PubMed ID: 17054723	2006
[Group B streptococcal vertebral osteomyelitis following superficial suppurative thrombophlebitis]. Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics\| PubMed ID: 17073295	2006
Factors associated with lower Mini Mental State Examination scores in elderly Japanese diabetes mellitus patients. Neurobiology of aging\| PubMed ID: 17434648	2008
Effects of human apolipoprotein E isoforms on the amyloid beta-protein concentration and lipid composition in brain low-density membrane domains. Journal of neurochemistry\| PubMed ID: 17472586	2007
Molecular basis of the shish-kebab morphology in polymer crystallization. Science (New York, N.Y.)\| PubMed ID: 17510361	2007
Differential mini-mental state examination profiles of older people with diabetes mellitus with early Alzheimer's disease. Journal of the American Geriatrics Society\| PubMed ID: 17537100	2007
BACE1 modulates filopodia-like protrusions induced by sodium channel beta4 subunit. Biochemical and biophysical research communications\| PubMed ID: 17644063	2007
Different effects of monocarboxylates on neuronal survival and beta-amyloid toxicity. The European journal of neuroscience\| PubMed ID: 17908170	2007
In vivo cerebral artery microangiography in rat and mouse using synchrotron radiation imaging system. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference\| PubMed ID: 18002858	2007
[Advanced fluorescence microscopes for future work]. Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme\| PubMed ID: 18051390	2007
Crystal structure of an active form of BACE1, an enzyme responsible for amyloid beta protein production. Molecular and cellular biology\| PubMed ID: 18378702	2008
Synthesis of 5''-branched derivatives of cyclic ADP-carbocyclic-ribose, a potent Ca2+-mobilizing agent: The first antagonists modified at the N1-ribose moiety. Bioorganic & medicinal chemistry letters\| PubMed ID: 18534848	2008
[A case of elderly onset loss of consciousness due to bacterial meningitis and subsequent vasculitis]. Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics\| PubMed ID: 18753720	2008
Loss of CO2-induced distensibility in cerebral arteries with chronic hypertension or vasospasm after subarachnoid hemorrhage. The Kobe journal of medical sciences\| PubMed ID: 18762726	2007
The double-edged effect of insulin on the neuronal cell death associated with hypoglycemia on the hippocampal slice culture. The Kobe journal of medical sciences\| PubMed ID: 18772618	2008
Membrane microdomain switching: a regulatory mechanism of amyloid precursor protein processing. The Journal of cell biology\| PubMed ID: 18936252	2008
Dilation of perforating arteries in rat brain in response to systemic hypotension is more sensitive and pronounced than that of pial arterioles: simultaneous visualization of perforating and... Microvascular research\| PubMed ID: 18992262	2009
Quantitative evaluation of bone resorption activity of osteoclast-like cells by measuring calcium phosphate resorbing area using incubator-facilitated and video-enhanced microscopy. Microscopy research and technique\| PubMed ID: 19003898	2009
Mutant SOD1 impairs axonal transport of choline acetyltransferase and acetylcholine release by sequestering KAP3. Human molecular genetics\| PubMed ID: 19088126	2009
Significant roles of microtubules in mature striated muscle deduced from the correlation between tubulin and its molecular chaperone alphaB-crystallin in rat muscles. The journal of physiological sciences : JPS\| PubMed ID: 19340546	2009
Pattern of rise in subplasma membrane Ca2+ concentration determines type of fusing insulin granules in pancreatic beta cells. Biochemical and biophysical research communications\| PubMed ID: 19426714	2009
Hasegawa Dementia Scale - revised, for screening of early Alzheimer's disease in the elderly with type 2 diabetes. Geriatrics & gerontology international\| PubMed ID: 19490145	2009
The temporomandibular joint in a rheumatoid arthritis patient after orthodontic treatment. The Angle orthodontist\| PubMed ID: 19537854	2009
Protective effect of lecithinized SOD on reactive oxygen species-induced xerostomia. Radiation research\| PubMed ID: 19708782	2009
Age-associated increase in abdominal obesity and insulin resistance, and usefulness of AHA/NHLBI definition of metabolic syndrome for predicting cardiovascular disease in Japanese elderly wi... Gerontology\| PubMed ID: 19828932	2010
Association of higher carbohydrate intake with depressive mood in elderly diabetic women. Nutritional neuroscience\| PubMed ID: 19925720	2009
Hypothalamic orexin stimulates feeding-associated glucose utilization in skeletal muscle via sympathetic nervous system. Cell metabolism\| PubMed ID: 19945404	2009
Education of lifestyle risk factors associated with dementia likely to help primary care physicians to improve consultation for elderly people with dementia. Journal of the American Geriatrics Society\| PubMed ID: 20169634	2009
Intravital oxygen radical imaging in normal and ischemic rat cortex. Neurosurgery\| PubMed ID: 20559099	2010
Tissue stiffness induced by prolonged immobilization of the rat knee joint and relevance of AGEs (pentosidine). Connective tissue research\| PubMed ID: 20604714	2010
Amyloid-β neurotoxicity restricts glucose window for neuronal survival in rat hippocampal slice cultures. Experimental gerontology\| PubMed ID: 20655378	2010
Usefulness of 18F-fluorodeoxyglucose positron emission tomography for diagnosis of asymptomatic giant cell arteritis in a patient with Alzheimer's disease. Geriatrics & gerontology international\| PubMed ID: 21166966	2011
Decrease in the density of t-tubular L-type Ca2+ channel currents in failing ventricular myocytes. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 21193586	2011
Causes of decreased activity of daily life in elderly patients who need daily living care. Geriatrics & gerontology international\| PubMed ID: 21272178	2011
Targets of the peroxisome proliferator-activated receptor γ agonist trials for the prevention of Alzheimer disease. Archives of neurology\| PubMed ID: 21482939	2011
The macrophage-mediated effects of the peroxisome proliferator-activated receptor-gamma agonist rosiglitazone attenuate tactile allodynia in the early phase of neuropathic pain development. Anesthesia and analgesia\| PubMed ID: 21490083	2011
Basic helix-loop-helix transcription factor DEC1 negatively regulates cyclin D1. The Journal of pathology\| PubMed ID: 21506129	2011
Effects of insulin and amyloid β(1-42) oligomers on glucose incorporation and mitochondrial function in cultured rat hippocampal neurons. Geriatrics & gerontology international\| PubMed ID: 21592272	2011
[Incretin analogues as a novel treatment strategy for Alzheimer's disease]. Nihon rinsho. Japanese journal of clinical medicine\| PubMed ID: 21595270	2011
Hydrolyzed eggshell membrane immobilized on phosphorylcholine polymer supplies extracellular matrix environment for human dermal fibroblasts. Cell and tissue research\| PubMed ID: 21597915	2011
Practical method to derive nonlinear response functions of cameras for scientific imaging. Applied optics\| PubMed ID: 21629319	2011
[Glucose intolerance and dementia]. Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics\| PubMed ID: 21778619	2011
Lidocaine attenuates the development of diabetic-induced tactile allodynia by inhibiting microglial activation. Anesthesia and analgesia\| PubMed ID: 21788310	2011
Fucoidan suppresses endocytosis in cultured HeLa cells. Chinese journal of integrative medicine\| PubMed ID: 21853347	2011
Role of amino-terminal half of the S4-S5 linker in type 1 ryanodine receptor (RyR1) channel gating. The Journal of biological chemistry\| PubMed ID: 21862589	2011
[Discussion meeting on the collaboration network between general practitioners and specialists for the diagnosis and management of patients with dementia]. Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine\| PubMed ID: 21899154	2011
Predictive factors for hospitalized and institutionalized care-giving of the aged patients with diabetes mellitus in Japan. The Kobe journal of medical sciences\| PubMed ID: 21937865	2011
Laminin α1 is essential for mouse cerebellar development. Matrix biology : journal of the International Society for Matrix Biology\| PubMed ID: 21983115	2012
Nitric oxide-induced calcium release via ryanodine receptors regulates neuronal function. The EMBO journal\| PubMed ID: 22036948	2012
Long-term multiple risk factor interventions in Japanese elderly diabetic patients: the Japanese Elderly Diabetes Intervention Trial--study design, baseline characteristics and effects of in... Geriatrics & gerontology international\| PubMed ID: 22435936	2012
Non-high-density lipoprotein cholesterol: an important predictor of stroke and diabetes-related mortality in Japanese elderly diabetic patients. Geriatrics & gerontology international\| PubMed ID: 22435937	2012
Relations of nutritional intake to age, sex and body mass index in Japanese elderly patients with type 2 diabetes: the Japanese Elderly Diabetes Intervention Trial. Geriatrics & gerontology international\| PubMed ID: 22435938	2012
Optimal energy distribution of carbohydrate intake for Japanese elderly patients with type 2 diabetes: the Japanese Elderly Intervention Trial. Geriatrics & gerontology international\| PubMed ID: 22435939	2012
Effects of total and green vegetable intakes on glycated hemoglobin A1c and triglycerides in elderly patients with type 2 diabetes mellitus: the Japanese Elderly Intervention Trial. Geriatrics & gerontology international\| PubMed ID: 22435940	2012
Dietary pattern and mortality in Japanese elderly patients with type 2 diabetes mellitus: does a vegetable- and fish-rich diet improve mortality? An explanatory study. Geriatrics & gerontology international\| PubMed ID: 22435941	2012
Lower physical activity, but not excessive calorie intake, is associated with metabolic syndrome in elderly with type 2 diabetes mellitus: the Japanese Elderly Diabetes Intervention Trial. Geriatrics & gerontology international\| PubMed ID: 22435942	2012
Lower physical activity is a strong predictor of cardiovascular events in elderly patients with type 2 diabetes mellitus beyond traditional risk factors: the Japanese Elderly Diabetes Interv... Geriatrics & gerontology international\| PubMed ID: 22435943	2012
Effective prevention of cardiovascular disease and diabetes-related events with atorvastatin in Japanese elderly patients with type 2 diabetes mellitus: adjusting for treatment changes using... Geriatrics & gerontology international\| PubMed ID: 22435944	2012
Risk factors associated with cognitive decline in the elderly with type 2 diabetes: baseline data analysis of the Japanese Elderly Diabetes Intervention Trial. Geriatrics & gerontology international\| PubMed ID: 22435945	2012
Risk factors associated with cognitive decline in the elderly with type 2 diabetes: pooled logistic analysis of a 6-year observation in the Japanese Elderly Diabetes Intervention Trial. Geriatrics & gerontology international\| PubMed ID: 22435946	2012
Risk factors for a 6-year decline in physical disability and functional limitations among elderly people with type 2 diabetes in the Japanese Elderly Diabetes Intervention Trial. Geriatrics & gerontology international\| PubMed ID: 22435947	2012
Factors associated with progression of diabetic nephropathy in Japanese elderly patients with type 2 diabetes: sub-analysis of the Japanese Elderly Diabetes Intervention Trial. Geriatrics & gerontology international\| PubMed ID: 22435948	2012
Pyruvate prevents the inhibition of the long-term potentiation induced by amyloid-β through protein phosphatase 2A inactivation. Journal of Alzheimer's disease : JAD\| PubMed ID: 22451307	2012
Multistep ion channel remodeling and lethal arrhythmia precede heart failure in a mouse model of inherited dilated cardiomyopathy. PloS one\| PubMed ID: 22514734	2012
Transplantation of side population cells restores the function of damaged exocrine glands through clusterin. Stem cells (Dayton, Ohio)\| PubMed ID: 22782911	2012
Role of fibroblast growth factor signaling in vascular formation and maintenance: orchestrating signaling networks as an integrated system. Wiley interdisciplinary reviews. Systems biology and medicine\| PubMed ID: 22930472	2012
Label-free characterization of living human induced pluripotent stem cells by subcellular topographic imaging technique using full-field quantitative phase microscopy coupled with interferen... Biomedical optics express\| PubMed ID: 23024911	2012
A warning index used in prescreening for Alzheimer's disease, based on self-reported cognitive deficits and vascular risk factors for dementia in elderly patients with type 2 diabetes. International journal of Alzheimer's disease\| PubMed ID: 23119223	2012
[Dementia in diabetes mellitus: preventive strategy]. Nihon rinsho. Japanese journal of clinical medicine\| PubMed ID: 23156446	2012
Inositol 1,4,5-trisphosphate receptor regulates replication, differentiation, infectivity and virulence of the parasitic protist Trypanosoma cruzi. Molecular microbiology\| PubMed ID: 23320762	2013
Usefulness of running wheel for detection of congestive heart failure in dilated cardiomyopathy mouse model. PloS one\| PubMed ID: 23383212	2013
Treatment of salivary gland hypofunction by transplantation with dental pulp cells. Archives of oral biology\| PubMed ID: 23570866	2013
Sperm-associated antigen 4, a novel hypoxia-inducible factor 1 target, regulates cytokinesis, and its expression correlates with the prognosis of renal cell carcinoma. The American journal of pathology\| PubMed ID: 23602831	2013
Design and synthesis of cyclic ADP-4-thioribose as a stable equivalent of cyclic ADP-ribose, a calcium ion-mobilizing second messenger. Angewandte Chemie (International ed. in English)\| PubMed ID: 23670921	2013
Cardiomyocyte FGF signaling is required for Cx43 phosphorylation and cardiac gap junction maintenance. Experimental cell research\| PubMed ID: 23742896	2013
[Risks for impaired daily life function in the elderly with type 2 diabetes in Japan]. Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics\| PubMed ID: 23925094	2013
[Metabolic syndrome and impaired daily life function in the elderly]. Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics\| PubMed ID: 23979234	2013
[Simple screening test using instrumental activities of daily living to find early stage of dementia]. Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics\| PubMed ID: 23979252	2013
Large-scale cell production of stem cells for clinical application using the automated cell processing machine. BMC biotechnology\| PubMed ID: 24228851	2013
Functional cooperation of metabotropic adenosine and glutamate receptors regulates postsynaptic plasticity in the cerebellum. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 24259587	2013
Axillary reverse mapping using fluorescence imaging is useful for identifying the risk group of postoperative lymphedema in breast cancer patients undergoing sentinel node biopsies. Journal of surgical oncology\| PubMed ID: 24310418	2014
Regional white matter lesions predict falls in patients with amnestic mild cognitive impairment and Alzheimer's disease. Journal of the American Medical Directors Association\| PubMed ID: 24359699	2014
[Cognitive decline in elderly individuals with type 2 diabetes mellitus]. Nihon rinsho. Japanese journal of clinical medicine\| PubMed ID: 24397166	2013
Evaluation of silicon nitride as a substrate for culture of PC12 cells: an interfacial model for functional studies in neurons. PloS one\| PubMed ID: 24587271	2014
Assembly of the cochlear gap junction macromolecular complex requires connexin 26. The Journal of clinical investigation\| PubMed ID: 24590285	2014
Inter-cellular exchange of cellular components via VE-cadherin-dependent trans-endocytosis. PloS one\| PubMed ID: 24603875	2014
Developing an interdisciplinary program of educational support for early-stage dementia patients and their family members: an investigation based on learning needs and attitude changes. Geriatrics & gerontology international\| PubMed ID: 24650063	2014
Factors associated with increased caregivers' burden in several cognitive stages of Alzheimer's disease. Geriatrics & gerontology international\| PubMed ID: 24650065	2014
Effect of cerumen impaction on hearing and cognitive functions in Japanese older adults with cognitive impairment. Geriatrics & gerontology international\| PubMed ID: 24650066	2014
Differential subtypes of diabetic older adults diagnosed with Alzheimer's disease. Geriatrics & gerontology international\| PubMed ID: 24650067	2014
Left ventricular diastolic dysfunction is associated with cerebral white matter lesions (leukoaraiosis) in elderly patients without ischemic heart disease and stroke. Geriatrics & gerontology international\| PubMed ID: 24650068	2014
Association of grip strength and related indices with independence of activities of daily living in older adults, investigated by a newly-developed grip strength measuring device. Geriatrics & gerontology international\| PubMed ID: 24650069	2014
Cell-to-cell propagation of intracellular signals fluorescently visualized with acridine orange in the gastric glands of guinea pigs. Biochemical and biophysical research communications\| PubMed ID: 24680825	2014
Two-dimensional microchemical observation of mast cell biogenic amine release as monitored by a 128 × 128 array-type charge-coupled device ion image sensor. Analytical chemistry\| PubMed ID: 24731060	2014
Mg(2+)- and ATP-dependent inhibition of transient receptor potential melastatin 7 by oxidative stress. Free radical biology & medicine\| PubMed ID: 24747489	2014
[Preventive strategy for cognitive decline in elderly with diabetes mellitus]. Nihon rinsho. Japanese journal of clinical medicine\| PubMed ID: 24796099	2014