Tarjei S. Mikkelsen

Broad Institute

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 63	2014

Other Publications

Article	Year
What makes us human? Genome biology\| PubMed ID: 15287969	2004
Improving genome annotations using phylogenetic profile anomaly detection. Bioinformatics (Oxford, England)\| PubMed ID: 15374867	2005
A human-specific gene in microglia. Science (New York, N.Y.)\| PubMed ID: 16151003	2005
DNA sequence and analysis of human chromosome 18. Nature\| PubMed ID: 16177791	2005
The case for selection at CCR5-Delta32. PLoS biology\| PubMed ID: 16248677	2005
Genome sequence, comparative analysis and haplotype structure of the domestic dog. Nature\| PubMed ID: 16341006	2005
DNA sequence and analysis of human chromosome 8. Nature\| PubMed ID: 16421571	2006
A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell\| PubMed ID: 16630819	2006
System-wide genomic and biochemical comparisons of sialic acid biology among primates and rodents: Evidence for two modes of rapid evolution. The Journal of biological chemistry\| PubMed ID: 16769723	2006
A second fatty acid amide hydrolase with variable distribution among placental mammals. The Journal of biological chemistry\| PubMed ID: 17015445	2006
Systematic discovery of regulatory motifs in conserved regions of the human genome, including thousands of CTCF insulator sites. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17442748	2007
Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences. Nature\| PubMed ID: 17495919	2007
Genome-wide maps of chromatin state in pluripotent and lineage-committed cells. Nature\| PubMed ID: 17603471	2007
Dissecting direct reprogramming through integrative genomic analysis. Nature\| PubMed ID: 18509334	2008
Genome-scale DNA methylation maps of pluripotent and differentiated cells. Nature\| PubMed ID: 18600261	2008
Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains. PLoS genetics\| PubMed ID: 18974828	2008
Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals. Nature\| PubMed ID: 19182780	2009
ZBED6, a novel transcription factor derived from a domesticated DNA transposon regulates IGF2 expression and muscle growth. PLoS biology\| PubMed ID: 20016685	2009
Genome-scale DNA methylation mapping of clinical samples at single-nucleotide resolution. Nature methods\| PubMed ID: 20062050	2010
Comparative epigenomic analysis of murine and human adipogenesis. Cell\| PubMed ID: 20887899	2010
The NIH Roadmap Epigenomics Mapping Consortium. Nature biotechnology\| PubMed ID: 20944595	2010
Mapping and analysis of chromatin state dynamics in nine human cell types. Nature\| PubMed ID: 21441907	2011
Systematic dissection and optimization of inducible enhancers in human cells using a massively parallel reporter assay. Nature biotechnology\| PubMed ID: 22371084	2012
A unique regulatory phase of DNA methylation in the early mammalian embryo. Nature\| PubMed ID: 22456710	2012
Integrative genomics identifies the corepressor SMRT as a gatekeeper of adipogenesis through the transcription factors C/EBPβ and KAISO. Molecular cell\| PubMed ID: 22521691	2012
Convergent and divergent evolution of genomic imprinting in the marsupial Monodelphis domestica. BMC genomics\| PubMed ID: 22899817	2012
Genome-wide map of quantified epigenetic changes during in vitro chondrogenic differentiation of primary human mesenchymal stem cells. BMC genomics\| PubMed ID: 23414147	2013
Systematic dissection of regulatory motifs in 2000 predicted human enhancers using a massively parallel reporter assay. Genome research\| PubMed ID: 23512712	2013
Cellular source and mechanisms of high transcriptome complexity in the mammalian testis. Cell reports\| PubMed ID: 23791531	2013
microRNA-140 targets RALA and regulates chondrogenic differentiation of human mesenchymal stem cells by translational enhancement of SOX9 and ACAN. Stem cells and development\| PubMed ID: 24063364	2014
Early B-cell factor-1 (EBF1) is a key regulator of metabolic and inflammatory signaling pathways in mature adipocytes. The Journal of biological chemistry\| PubMed ID: 24174531	2013
High-resolution mapping reveals a conserved, widespread, dynamic mRNA methylation program in yeast meiosis. Cell\| PubMed ID: 24269006	2013
Genome-scale CRISPR-Cas9 knockout screening in human cells. Science (New York, N.Y.)\| PubMed ID: 24336571	2014
Brief report: importance of SOX8 for in vitro chondrogenic differentiation of human mesenchymal stromal cells. Stem cells (Dayton, Ohio)\| PubMed ID: 24449344	2014
The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells. Nature biotechnology\| PubMed ID: 24658644	2014
ZBED6 modulates the transcription of myogenic genes in mouse myoblast cells. PloS one\| PubMed ID: 24714595	2014
Analysis of the effects of five factors relevant to in vitro chondrogenesis of human mesenchymal stem cells using factorial design and high throughput mRNA-profiling. PloS one\| PubMed ID: 24816923	2014
The regulatory landscape of osteogenic differentiation. Stem cells (Dayton, Ohio)\| PubMed ID: 24898411	2014
Comprehensive mutational scanning of a kinase in vivo reveals substrate-dependent fitness landscapes. Nucleic acids research\| PubMed ID: 24914046	2014
Perturbation of m6A Writers Reveals Two Distinct Classes of mRNA Methylation at Internal and 5' Sites. Cell reports\| PubMed ID: 24981863	2014