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Sibylle Mittnacht

Cancer Biology, UCL Cancer Institute

Affiliated withUCL Cancer Institute

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 5	2014

Other Publications

Article	Year
p16INK4a loss and sensitivity in KSHV associated primary effusion lymphoma. Oncogene\| PubMed ID: 11896614	2002
RB activation defect in tumor cell lines. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12379745	2002
Crystal structure of the retinoblastoma tumor suppressor protein bound to E2F and the molecular basis of its regulation. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12598654	2003
High-throughput screening for the identification of small-molecule inhibitors of retinoblastoma protein phosphorylation in cells. Analytical biochemistry\| PubMed ID: 12895470	2003
A novel constitutional mutation affecting splicing of retinoblastoma tumor suppressor gene intron 23 causes partial loss of pRB activity. Human mutation\| PubMed ID: 15643604	2005
The retinoblastoma protein--from bench to bedside. European journal of cell biology\| PubMed ID: 15819393	2005
Selective ablation of retinoblastoma protein function by the RET finger protein. Molecular cell\| PubMed ID: 15837424	2005
Regulation of microfilament organization by Kaposi sarcoma-associated herpes virus-cyclin.CDK6 phosphorylation of caldesmon. The Journal of biological chemistry\| PubMed ID: 16115893	2005
Direct interaction between the catalytic subunit of Protein Phosphatase 1 and pRb. Cancer cell international\| PubMed ID: 16466572	2006
Trans-activation of the DNA-damage signalling protein kinase Chk2 by T-loop exchange. The EMBO journal\| PubMed ID: 16794575	2006
Attenuation of disease phenotype through alternative translation initiation in low-penetrance retinoblastoma. Human mutation\| PubMed ID: 16988938	2007
Crystal structure of the retinoblastoma protein N domain provides insight into tumor suppression, ligand interaction, and holoprotein architecture. Molecular cell\| PubMed ID: 17996702	2007
p53-Driven apoptosis limits centrosome amplification and genomic instability downstream of NPM1 phosphorylation. Nature cell biology\| PubMed ID: 18454140	2008
Nonsense-mediated decay: paving the road for genome diversification. BioEssays : news and reviews in molecular, cellular and developmental biology\| PubMed ID: 18798540	2008
Cyclin-cyclin-dependent kinase regulatory response is linked to substrate recognition. The Journal of biological chemistry\| PubMed ID: 21233209	2011
Mechanism-based screen for G1/S checkpoint activators identifies a selective activator of EIF2AK3/PERK signalling. PloS one\| PubMed ID: 22253692	2012
Mechanism-based screen establishes signalling framework for DNA damage-associated G1 checkpoint response. PloS one\| PubMed ID: 22384045	2012
Role of the tripartite motif protein 27 in cancer development. Journal of the National Cancer Institute\| PubMed ID: 22556269	2012
Structural insights into the mechanism of phosphoregulation of the retinoblastoma protein. PloS one\| PubMed ID: 23516486	2013