Aurel Perren

Institute of Pathology, University of Bern

Research Area

Biography

Aurel Perren has not added Biography.
If you are Aurel Perren and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 66	2014

Other Publications

Article	Year
Loss of heterozygosity at chromosome 6q23-25 correlates with clinical and histologic parameters in salivary gland adenoid cystic carcinoma. Virchows Archiv : an international journal of pathology\| PubMed ID: 11942580	2002
Absence of somatic SDHD mutations in sporadic neuroendocrine tumors and detection of two germline variants in paraganglioma patients. Oncogene\| PubMed ID: 12386824	2002
Secretory apparatus assessed by analysis of pancreatic secretory stress protein expression in a rat model of chronic pancreatitis. Cell and tissue research\| PubMed ID: 12764608	2003
Morphologic changes and altered gene expression in an epithelioid hemangioendothelioma during a ten-year course of disease. Pathology, research and practice\| PubMed ID: 12812318	2003
Lymph node surgery in papillary thyroid carcinoma. Journal of the American College of Surgeons\| PubMed ID: 12892795	2003
DPC4/Smad4: no mutations, rare allelic imbalances, and retained protein expression in pancreatic endocrine tumors. Diagnostic molecular pathology : the American journal of surgical pathology, part B\| PubMed ID: 14639103	2003
A novel succinate dehydrogenase subunit B gene mutation, H132P, causes familial malignant sympathetic extraadrenal paragangliomas. The Journal of clinical endocrinology and metabolism\| PubMed ID: 14715873	2004
Coordinate regulation of PSP/reg and PAP isoforms as a family of secretory stress proteins in an animal model of chronic pancreatitis. The Journal of surgical research\| PubMed ID: 15100001	2004
The gastroenteropancreatic neuroendocrine cell system and its tumors: the WHO classification. Annals of the New York Academy of Sciences\| PubMed ID: 15153416	2004
Molecular genetics of gastroenteropancreatic endocrine tumors. Annals of the New York Academy of Sciences\| PubMed ID: 15153435	2004
Absence of BRAF gene mutations differentiates spitz nevi from malignant melanoma. Anticancer research\| PubMed ID: 15330192	2004
Abnormalities of proinsulin processing in functioning insulinomas: clinical implications. Clinical endocrinology\| PubMed ID: 15473873	2004
Persistent hyperinsulinemic hypoglycemia in 15 adults with diffuse nesidioblastosis: diagnostic criteria, incidence, and characterization of beta-cell changes. The American journal of surgical pathology\| PubMed ID: 15767809	2005
Precursor lesions in patients with multiple endocrine neoplasia type 1-associated duodenal gastrinomas. Gastroenterology\| PubMed ID: 15887103	2005
Caseous calcification of the mitral annulus. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 15942592	2005
Assessment of Helicobacter pylori clarithromycin resistance mutations in archival gastric biopsy samples. Swiss medical weekly\| PubMed ID: 16034687	2005
Fatal esophageal perforation caused by invasive candidiasis. The Annals of thoracic surgery\| PubMed ID: 16122508	2005
Exocrine meets endocrine: pancreatic stone protein and regenerating protein--two sides of the same coin. The Journal of surgical research\| PubMed ID: 16360171	2006
Microadenomatosis of the endocrine pancreas in patients with and without the multiple endocrine neoplasia type 1 syndrome. The American journal of surgical pathology\| PubMed ID: 16699310	2006
Pancreatic endocrine tumors are a rare manifestation of the neurofibromatosis type 1 phenotype: molecular analysis of a malignant insulinoma in a NF-1 patient. The American journal of surgical pathology\| PubMed ID: 16861979	2006
Sporadic versus hereditary gastrinomas of the duodenum and pancreas: distinct clinico-pathological and epidemiological features. World journal of gastroenterology : WJG\| PubMed ID: 17006979	2006
Multiple endocrine neoplasia type 1 (MEN1): loss of one MEN1 allele in tumors and monohormonal endocrine cell clusters but not in islet hyperplasia of the pancreas. The Journal of clinical endocrinology and metabolism\| PubMed ID: 17179192	2007
Hypoglycemia due to paraneoplastic secretion of insulin-like growth factor-I in a patient with metastasizing large-cell carcinoma of the lung. The Journal of clinical endocrinology and metabolism\| PubMed ID: 17299065	2007
Recurrent hypoglycaemia in HIV-positive narcotic addicts. Swiss medical weekly\| PubMed ID: 17299659	2006
Gastrinoma (duodenal and pancreatic). Neuroendocrinology\| PubMed ID: 17312377	2006
Superiority of small islets in human islet transplantation. Diabetes\| PubMed ID: 17327426	2007
Familial pheochromocytomas and paragangliomas: stories from the sign-out room. Endocrine pathology\| PubMed ID: 17525482	2006
Increased number of islet-associated macrophages in type 2 diabetes. Diabetes\| PubMed ID: 17579207	2007
Carcinogenic hypergastrinemia: signet-ring cell carcinoma in a patient with multiple endocrine neoplasia type 1 with Zollinger-Ellison's syndrome. The Journal of clinical endocrinology and metabolism\| PubMed ID: 17609302	2007
Candidate gene mutation analysis in bilateral adrenal pheochromocytoma and sympathetic paraganglioma. Endocrine-related cancer\| PubMed ID: 17639058	2007
CK19 and CD99 immunoexpression profile in goblet cell (mucin-producing neuroendocrine tumors) and classical carcinoids of the vermiform appendix. International journal of surgical pathology\| PubMed ID: 17652531	2007
Cytokeratins 7 and 20 immunoexpression profile in goblet cell and classical carcinoids of appendix. Endocrine pathology\| PubMed ID: 17652796	2007
Site-specific biology and pathology of gastroenteropancreatic neuroendocrine tumors. Virchows Archiv : an international journal of pathology\| PubMed ID: 17684761	2007
Hereditary neuroendocrine tumors of the gastroenteropancreatic system. Virchows Archiv : an international journal of pathology\| PubMed ID: 17684762	2007
Molecular profiles of gastroenteropancreatic endocrine tumors. Virchows Archiv : an international journal of pathology\| PubMed ID: 17684763	2007
Endocrine precursor lesions and microadenomas of the duodenum and pancreas with and without MEN1: criteria, molecular concepts and clinical significance. Pathobiology : journal of immunopathology, molecular and cellular biology\| PubMed ID: 17890894	2007
Endocrine precursor lesions of gastroenteropancreatic neuroendocrine tumors. Endocrine pathology\| PubMed ID: 18058264	2007
WHO 2004 criteria and CK19 are reliable prognostic markers in pancreatic endocrine tumors. The American journal of surgical pathology\| PubMed ID: 18059224	2007
Adult diffuse nesidioblastosis: genetically or environmentally induced? Human pathology\| PubMed ID: 18070631	2008
Consensus guidelines for the management of patients with liver metastases from digestive (neuro)endocrine tumors: foregut, midgut, hindgut, and unknown primary. Neuroendocrinology\| PubMed ID: 18097131	2008
Islet inflammation in type 2 diabetes: from metabolic stress to therapy. Diabetes care\| PubMed ID: 18227479	2008
Islet 1 (Isl1) expression is a reliable marker for pancreatic endocrine tumors and their metastases. The American journal of surgical pathology\| PubMed ID: 18300808	2008
Somatostatin-producing neuroendocrine tumors of the duodenum and pancreas: incidence, types, biological behavior, association with inherited syndromes, and functional activity. Endocrine-related cancer\| PubMed ID: 18310290	2008
Primary lymph node gastrinoma or occult duodenal microgastrinoma with lymph node metastases in a MEN1 patient: the need for a systematic search for the primary tumor. The American journal of surgical pathology\| PubMed ID: 18520436	2008
Correlation of matrix metalloproteinases and tissue inhibitors of matrix metalloproteinase expression in ileal carcinoids, lymph nodes and liver metastasis with prognosis and survival. Neuroendocrinology\| PubMed ID: 18708724	2009
Correlation of immunohistopathological expression of somatostatin receptor 2 with standardised uptake values in 68Ga-DOTATOC PET/CT. European journal of nuclear medicine and molecular imaging\| PubMed ID: 18807033	2009
Glucagon cell adenomatosis: a newly recognized disease of the endocrine pancreas. The Journal of clinical endocrinology and metabolism\| PubMed ID: 18957496	2009
Insulinomatosis: a multicentric insulinoma disease that frequently causes early recurrent hyperinsulinemic hypoglycemia. The American journal of surgical pathology\| PubMed ID: 19011561	2009
ENETS Consensus Guidelines for the Standards of Care in Neuroendocrine Tumors: towards a standardized approach to the diagnosis of gastroenteropancreatic neuroendocrine tumors and their prog... Neuroendocrinology\| PubMed ID: 19060454	2009
Novel multiple, monoallelic KRAS mutations at codon 12 and 13. International journal of cancer. Journal international du cancer\| PubMed ID: 19521964	2009
An immunohistochemical procedure to detect patients with paraganglioma and phaeochromocytoma with germline SDHB, SDHC, or SDHD gene mutations: a retrospective and prospective analysis. The Lancet. Oncology\| PubMed ID: 19576851	2009
Vascular endothelial growth factors, angiogenesis, and survival in human ileal enterochromaffin cell carcinoids. Neuroendocrinology\| PubMed ID: 19816005	2009
Anti insulin-like growth factor I receptor immunoliposomes: a single formulation combining two anticancer treatments with enhanced therapeutic efficiency. The Journal of clinical endocrinology and metabolism\| PubMed ID: 19952224	2010
Hyperglycaemia but not hyperlipidaemia decreases serum amylase and increases neutrophils in the exocrine pancreas of cats. Research in veterinary science\| PubMed ID: 20132955	2010
The ENETS and AJCC/UICC TNM classifications of the neuroendocrine tumors of the gastrointestinal tract and the pancreas: a statement. Virchows Archiv : an international journal of pathology\| PubMed ID: 20422210	2010
VHL-gene deletion in single renal tubular epithelial cells and renal tubular cysts: further evidence for a cyst-dependent progression pathway of clear cell renal carcinoma in von Hippel-Lind... The American journal of surgical pathology\| PubMed ID: 20431476	2010
ENETS consensus guidelines for the management of brain, cardiac and ovarian metastases from neuroendocrine tumors. Neuroendocrinology\| PubMed ID: 20453466	2010
Multicentre validation study of nucleic acids extraction from FFPE tissues. Virchows Archiv : an international journal of pathology\| PubMed ID: 20665046	2010
SDHB loss predicts malignancy in pheochromocytomas/sympathethic paragangliomas, but not through hypoxia signalling. Endocrine-related cancer\| PubMed ID: 20702724	2010
[Pathology of malignant lymphomas--clarity instead of confusion]. Therapeutische Umschau. Revue thérapeutique\| PubMed ID: 20886454	2010
Pheochromocytoma in rats with multiple endocrine neoplasia (MENX) shares gene expression patterns with human pheochromocytoma. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 20937862	2010
Clinical aspects, diagnostic challenges and management of patients with neuroendocrine tumors (NETs). Onkologie\| PubMed ID: 21358221	2011
Impact of CD39 and purinergic signalling on the growth and metastasis of colorectal cancer. Purinergic signalling\| PubMed ID: 21484085	2011
Glucagon-like peptide-1 versus somatostatin receptor targeting reveals 2 distinct forms of malignant insulinomas. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 21680696	2011
The Ras inhibitors caveolin-1 and docking protein 1 activate peroxisome proliferator-activated receptor γ through spatial relocalization at helix 7 of its ligand-binding domain. Molecular and cellular biology\| PubMed ID: 21690289	2011
Serotonin-producing enterochromaffin cell tumors of the pancreas: clinicopathologic study of 15 cases and comparison with intestinal enterochromaffin cell tumors. Pancreas\| PubMed ID: 21705949	2011
Are biochemical markers of neuroendocrine tumors coreleased with insulin following local calcium stimulation in patients with insulinomas? Pancreas\| PubMed ID: 21705951	2011
Hormonally defined pancreatic and duodenal neuroendocrine tumors differ in their transcription factor signatures: expression of ISL1, PDX1, NGN3, and CDX2. Virchows Archiv : an international journal of pathology\| PubMed ID: 21739268	2011
Functional Imaging of Pheochromocytoma with Ga-DOTATOC and C-HED in a Genetically Defined Rat Model of Multiple Endocrine Neoplasia. International journal of molecular imaging\| PubMed ID: 21755051	2011
Deletions of 11q22.3-q25 are associated with atypical lung carcinoids and poor clinical outcome. The American journal of pathology\| PubMed ID: 21763262	2011
Better provenance for biobank samples. Nature\| PubMed ID: 21796190	2011
Sclerosing angiomatoid nodular transformation of the spleen presenting as a rapidly growing tumour in a patient with rectal cancer. BMJ case reports\| PubMed ID: 21918654	2009
Poorly differentiated thyroid carcinomas: how much poorly differentiated is needed? The American journal of surgical pathology\| PubMed ID: 21989341	2011
Malignant pheochromocytomas and paragangliomas: a diagnostic challenge. Langenbeck's archives of surgery / Deutsche Gesellschaft für Chirurgie\| PubMed ID: 22124609	2012
Somatostatin receptor subtype 2A immunohistochemistry using a new monoclonal antibody selects tumors suitable for in vivo somatostatin receptor targeting. The American journal of surgical pathology\| PubMed ID: 22251942	2012
ENETS Consensus Guidelines for the management of patients with neuroendocrine neoplasms from the jejuno-ileum and the appendix including goblet cell carcinomas. Neuroendocrinology\| PubMed ID: 22262080	2012
Atypical presentation of a hormonally active adrenocortical tumor in an adolescent leading to delayed diagnosis. Hormones (Athens, Greece)\| PubMed ID: 22281889	2011
Poorly differentiated oncocytic thyroid carcinoma--diagnostic implications and outcome. Histopathology\| PubMed ID: 22348590	2012
Lymphotoxin Î² Receptor Signaling Promotes Development of Autoimmune Pancreatitis. Gastroenterology\| PubMed ID: 22863765	2012
MicroRNA expression array identifies novel diagnostic markers for conventional and oncocytic follicular thyroid carcinomas. The Journal of clinical endocrinology and metabolism\| PubMed ID: 23150679	2013
Comprehensive MicroRNA expression profiling identifies novel markers in follicular variant of papillary thyroid carcinoma. Thyroid : official journal of the American Thyroid Association\| PubMed ID: 23427895	2013
ISL1 expression is not restricted to pancreatic well-differentiated neuroendocrine neoplasms, but is also commonly found in well and poorly differentiated neuroendocrine neoplasms of extrapa... Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc\| PubMed ID: 23503646	2013
Next-generation tissue microarray (ngTMA) increases the quality of biomarker studies: an example using CD3, CD8, and CD45RO in the tumor microenvironment of six different solid tumor types. Journal of translational medicine\| PubMed ID: 23627766	2013
Evaluation of the Hepa Wash® treatment in pigs with acute liver failure. BMC gastroenterology\| PubMed ID: 23668774	2013
Diagnostic and prognostic implications of the PAX8-PPARγ translocation in thyroid carcinomas-a TMA-based study of 226 cases. Histopathology\| PubMed ID: 23738683	2013
Determination of the molecular subtypes of diffuse large B-cell lymphomas using immunohistochemistry: a case series from the Inselspital, Bern, and a critical appraisal of this determination... Swiss medical weekly\| PubMed ID: 23740154	2013
Intraductal papillary neoplasms of the bile duct: stepwise progression to carcinoma involves common molecular pathways. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc\| PubMed ID: 23828315	2014
CCND1/CyclinD1 status in metastasizing bladder cancer: a prognosticator and predictor of chemotherapeutic response. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc\| PubMed ID: 23887292	2014
ATG5 is induced by DNA-damaging agents and promotes mitotic catastrophe independent of autophagy. Nature communications\| PubMed ID: 23945651	2013
Loss of DAXX and ATRX are associated with chromosome instability and reduced survival of patients with pancreatic neuroendocrine tumors. Gastroenterology\| PubMed ID: 24148618	2014
MEN1 gene mutation and reduced expression are associated with poor prognosis in pulmonary carcinoids. The Journal of clinical endocrinology and metabolism\| PubMed ID: 24276465	2014
Loss of Raf-1 kinase inhibitor protein (RKIP) is strongly associated with high-grade tumor budding and correlates with an aggressive phenotype in pancreatic ductal adenocarcinoma (PDAC). Journal of translational medicine\| PubMed ID: 24330423	2013
MicroRNA profile of poorly differentiated thyroid carcinomas: new diagnostic and prognostic insights. Journal of molecular endocrinology\| PubMed ID: 24443580	2014
Tumor regression grade of urothelial bladder cancer after neoadjuvant chemotherapy: a novel and successful strategy to predict survival. The American journal of surgical pathology\| PubMed ID: 24525502	2014
Diagnosis and interdisciplinary treatment of a botryoid odontogenic cyst in the posterior mandible: report of a case. Quintessence international (Berlin, Germany : 1985)\| PubMed ID: 24570990	2014
Glucagon-like peptide-1 receptor imaging for the localisation of insulinomas: a prospective multicentre imaging study. The lancet. Diabetes & endocrinology\| PubMed ID: 24622317	2013
Hyperplasia to neoplasia sequence of duodenal and pancreatic neuroendocrine diseases and pseudohyperplasia of the PP-cells in the pancreas. Endocrine pathology\| PubMed ID: 24718881	2014
Novel prognostic markers revealed by a proteomic approach separating benign from malignant insulinomas. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc\| PubMed ID: 24947143	2014
Prognostic and Predictive Roles of MGMT Protein Expression and Promoter Methylation in Sporadic Pancreatic Neuroendocrine Neoplasms. Neuroendocrinology\| PubMed ID: 25012122	2014
Evaluation of colon cancer histomorphology: a comparison between formalin and PAXgene tissue fixation by an international ring trial. Virchows Archiv : an international journal of pathology\| PubMed ID: 25085759	2014
Glucagon-like-peptide-1 receptor expression in normal and diseased human thyroid and pancreas. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc\| PubMed ID: 25216224	2014