Hugues Lortat-Jacob

Institut de Biologie Structurale

Affiliated withInstitut de Biologie Structurale

Research Area

Biography

Hugues Lortat-Jacob has not added Biography.
If you are Hugues Lortat-Jacob and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 4	2014

Other Publications

Article	Year
Sulfated polysaccharides increase plasma levels of SDF-1 in monkeys and mice: involvement in mobilization of stem/progenitor cells. Blood\| PubMed ID: 11756151	2002
Structural diversity of heparan sulfate binding domains in chemokines. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 11830659	2002
Heparan sulfate-mediated binding of infectious dengue virus type 2 and yellow fever virus. Virology\| PubMed ID: 11878919	2002
Cell membrane GM1 ganglioside is a functional coreceptor for fibroblast growth factor 2. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 11917140	2002
Cellular glycosaminoglycans and low density lipoprotein receptor are involved in hepatitis C virus adsorption. Journal of medical virology\| PubMed ID: 12210409	2002
Heparin-aggregated RANTES can be crystallised. Acta crystallographica. Section D, Biological crystallography\| PubMed ID: 12351884	2002
Human cytomegalovirus binding to DC-SIGN is required for dendritic cell infection and target cell trans-infection. Immunity\| PubMed ID: 12433371	2002
Adenovirus protein involved in virus internalization recruits ubiquitin-protein ligases. Biochemistry\| PubMed ID: 12450395	2002
A kinetics and modeling study of RANTES(9-68) binding to heparin reveals a mechanism of cooperative oligomerization. Biochemistry\| PubMed ID: 12475226	2002
DC-SIGN and L-SIGN are high affinity binding receptors for hepatitis C virus glycoprotein E2. The Journal of biological chemistry\| PubMed ID: 12609975	2003
Normal human keratinocytes bind to the alpha3LG4/5 domain of unprocessed laminin-5 through the receptor syndecan-1. The Journal of biological chemistry\| PubMed ID: 12947106	2003
Characterization of endostatin binding to heparin and heparan sulfate by surface plasmon resonance and molecular modeling: role of divalent cations. The Journal of biological chemistry\| PubMed ID: 14585835	2004
Heparan sulfate proteoglycan mediates the selective attachment and internalization of serotype 3 human adenovirus dodecahedron. Virology\| PubMed ID: 15051392	2004
NMR characterization of the interaction between the C-terminal domain of interferon-gamma and heparin-derived oligosaccharides. The Biochemical journal\| PubMed ID: 15270718	2004
Heparan sulfate/heparin oligosaccharides protect stromal cell-derived factor-1 (SDF-1)/CXCL12 against proteolysis induced by CD26/dipeptidyl peptidase IV. The Journal of biological chemistry\| PubMed ID: 15292258	2004
Synthesis of tailor-made glycoconjugate mimetics of heparan sulfate that bind IFN-gamma in the nanomolar range. Chemistry (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 15352109	2004
A novel strategy for defining critical amino acid residues involved in protein/glycosaminoglycan interactions. The Journal of biological chemistry\| PubMed ID: 15485868	2004
Glycosaminoglycans and protein disulfide isomerase-mediated reduction of HIV Env. Molecular pharmacology\| PubMed ID: 15644496	2005
Heparan sulfate targets the HIV-1 envelope glycoprotein gp120 coreceptor binding site. The Journal of biological chemistry\| PubMed ID: 15797855	2005
The fucose-binding lectin from Ralstonia solanacearum. A new type of beta-propeller architecture formed by oligomerization and interacting with fucoside, fucosyllactose, and plant xyloglucan... The Journal of biological chemistry\| PubMed ID: 15923179	2005
Heparan sulfate mimicry: a synthetic glycoconjugate that recognizes the heparin binding domain of interferon-gamma inhibits the cytokine activity. The Journal of biological chemistry\| PubMed ID: 16155294	2005
Heparan sulphate proteoglycans and viral vectors : ally or foe? Current gene therapy\| PubMed ID: 16475944	2006
Mannose hyperbranched dendritic polymers interact with clustered organization of DC-SIGN and inhibit gp120 binding. FEBS letters\| PubMed ID: 16616922	2006
Structural and mutational analysis of human Ad37 and canine adenovirus 2 fiber heads in complex with the D1 domain of coxsackie and adenovirus receptor. The Journal of biological chemistry\| PubMed ID: 16923808	2006
Organization of human interferon gamma-heparin complexes from solution properties and hydrodynamics. Biochemistry\| PubMed ID: 17073444	2006
Structural view of glycosaminoglycan-protein interactions. Carbohydrate research\| PubMed ID: 17229412	2007
Adenovirus dodecahedron cell attachment and entry are mediated by heparan sulfate and integrins and vary along the cell cycle. Virology\| PubMed ID: 17950396	2008
The novel CXCL12gamma isoform encodes an unstructured cationic domain which regulates bioactivity and interaction with both glycosaminoglycans and CXCR4. PloS one\| PubMed ID: 17971873	2007
Efficient long-term and high-yielded production of a recombinant proteoglycan in eukaryotic HEK293 cells using a membrane-based bioreactor. Biochemical and biophysical research communications\| PubMed ID: 18261977	2008
Relationships between glycosaminoglycan and receptor binding sites in chemokines-the CXCL12 example. Carbohydrate research\| PubMed ID: 18334249	2008
Polypyrrole oligosaccharide array and surface plasmon resonance imaging for the measurement of glycosaminoglycan binding interactions. Analytical chemistry\| PubMed ID: 18348577	2008
The HIV-1 envelope glycoprotein gp120 features four heparan sulfate binding domains, including the co-receptor binding site. The Journal of biological chemistry\| PubMed ID: 18378683	2008
Direct peptide interaction with surface glycosaminoglycans contributes to the cell penetration of maurocalcine. The Journal of biological chemistry\| PubMed ID: 18603532	2008
The CXCL12gamma chemokine displays unprecedented structural and functional properties that make it a paradigm of chemoattractant proteins. PloS one\| PubMed ID: 18648536	2008
The cell adhesion molecule "CAR" and sialic acid on human erythrocytes influence adenovirus in vivo biodistribution. PLoS pathogens\| PubMed ID: 19119424	2009
Tyrosine dephosphorylation of the syndecan-1 PDZ binding domain regulates syntenin-1 recruitment. The Journal of biological chemistry\| PubMed ID: 19228696	2009
The signal peptide of Staphylococcus aureus panton valentine leukocidin LukS component mediates increased adhesion to heparan sulfates. PloS one\| PubMed ID: 19347045	2009
Heparan sulfate proteoglycans are receptors for the cell-surface trafficking and biological activity of transglutaminase-2. The Journal of biological chemistry\| PubMed ID: 19398782	2009
Structure and functional relevance of the Slit2 homodimerization domain. EMBO reports\| PubMed ID: 19498462	2009
A synthetic CD4-heparan sulfate glycoconjugate inhibits CCR5 and CXCR4 HIV-1 attachment and entry. Nature chemical biology\| PubMed ID: 19734912	2009
The molecular basis and functional implications of chemokine interactions with heparan sulphate. Current opinion in structural biology\| PubMed ID: 19800217	2009
HABA-based ionic liquid matrices for UV-MALDI-MS analysis of heparin and heparan sulfate oligosaccharides. Glycobiology\| PubMed ID: 19858171	2010
A cell-penetrating peptide derived from human lactoferrin with conformation-dependent uptake efficiency. The Journal of biological chemistry\| PubMed ID: 19858187	2009
Dynamics of heparan sulfate explored by neutron scattering. Physical chemistry chemical physics : PCCP\| PubMed ID: 20336244	2010
Cutting edge: C1q binds deoxyribose and heparan sulfate through neighboring sites of its recognition domain. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 20548024	2010
Characterization and binding activity of the chondroitin/dermatan sulfate chain from Endocan, a soluble endothelial proteoglycan. Glycobiology\| PubMed ID: 20581009	2010
Identification of tubular heparan sulfate as a docking platform for the alternative complement component properdin in proteinuric renal disease. The Journal of biological chemistry\| PubMed ID: 21135110	2011
Hijacking of the pleiotropic cytokine interferon-γ by the type III secretion system of Yersinia pestis. PloS one\| PubMed ID: 21179438	2010
13C-labeled heparan sulfate analogue as a tool to study protein/heparan sulfate interactions by NMR spectroscopy: application to the CXCL12α chemokine. Journal of the American Chemical Society\| PubMed ID: 21634378	2011
Cxcl12 evolution--subfunctionalization of a ligand through altered interaction with the chemokine receptor. Development (Cambridge, England)\| PubMed ID: 21693511	2011
Semen clusterin is a novel DC-SIGN ligand. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 22013110	2011
A synthetic heparan sulfate-mimetic peptide conjugated to a mini CD4 displays very high anti- HIV-1 activity independently of coreceptor usage. Chemistry & biology\| PubMed ID: 22284360	2012
Cell surface proteoglycans syndecan-1 and -4 bind overlapping but distinct sites in laminin α3 LG45 protein domain. The Journal of biological chemistry\| PubMed ID: 22351752	2012
Transglutaminase-2 interaction with heparin: identification of a heparin binding site that regulates cell adhesion to fibronectin-transglutaminase-2 matrix. The Journal of biological chemistry\| PubMed ID: 22442151	2012
Factor h and properdin recognize different epitopes on renal tubular epithelial heparan sulfate. The Journal of biological chemistry\| PubMed ID: 22815489	2012
Continuous evolution profiles for electronic-tongue-based analysis. Angewandte Chemie (International ed. in English)\| PubMed ID: 22968809	2012
Homeostatic and tissue reparation defaults in mice carrying selective genetic invalidation of CXCL12/proteoglycan interactions. Circulation\| PubMed ID: 23035208	2012
A New C-Xyloside induces modifications of GAG expression, structure and functional properties. PloS one\| PubMed ID: 23110134	2012
Toward libraries of biotinylated chondroitin sulfate analogues: from synthesis to in vivo studies. Chemistry (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 23154924	2013
Inflammatory chemokines direct and restrict leukocyte migration within live tissues as glycan-bound gradients. Current biology : CB\| PubMed ID: 23219724	2012
HSulf sulfatases catalyze processive and oriented 6-O-desulfation of heparan sulfate that differentially regulates fibroblast growth factor activity. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 23457216	2013
Insights into the mechanism by which interferon-γ basic amino acid clusters mediate protein binding to heparan sulfate. Journal of the American Chemical Society\| PubMed ID: 23734709	2013
The disulfide bond between cysteine 10 and cysteine 34 is required for CCL18 activity. Cytokine\| PubMed ID: 23742785	2013
Human immunodeficiency virus and heparan sulfate: from attachment to entry inhibition. Frontiers in immunology\| PubMed ID: 24312095	2013
Post-Synthetic Regulation of HS Structure: The Yin and Yang of the Sulfs in Cancer. Frontiers in oncology\| PubMed ID: 24459635	2014
The effect of delivering the chemokine SDF-1α in a matrix-bound manner on myogenesis. Biomaterials\| PubMed ID: 24612919	2014
Importance of the polarity of the glycosaminoglycan chain on the interaction with FGF-1. Glycobiology\| PubMed ID: 25015527	2014
Well-defined biomimetic surfaces to characterize glycosaminoglycan-mediated interactions on the molecular, supramolecular and cellular levels. Biomaterials\| PubMed ID: 25088726	2014