Sina Bavari

Division of Molecular and Translational Sciences, US Army Medical Research Institute of Infectious Diseases

Affiliated withUS Army Medical Research Institute of Infectious Diseases

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 3	2014

Other Publications

Article	Year
Production and purification of a recombinant Staphylococcal enterotoxin B vaccine candidate expressed in Escherichia coli. Protein expression and purification\| PubMed ID: 11858726	2002
Lipid raft microdomains: a gateway for compartmentalized trafficking of Ebola and Marburg viruses. The Journal of experimental medicine\| PubMed ID: 11877482	2002
Protection against bacterial superantigen staphylococcal enterotoxin B by passive vaccination. Infection and immunity\| PubMed ID: 11953360	2002
Humanlike immune response of human leukocyte antigen-DR3 transgenic mice to staphylococcal enterotoxins: a novel model for superantigen vaccines. The Journal of infectious diseases\| PubMed ID: 12085321	2002
Lethal shock induced by streptococcal pyrogenic exotoxin A in mice transgenic for human leukocyte antigen-DQ8 and human CD4 receptors: implications for development of vaccines and therapeuti... The Journal of infectious diseases\| PubMed ID: 12195377	2002
Molecular mechanisms of filovirus cellular trafficking. Microbes and infection / Institut Pasteur\| PubMed ID: 12787740	2003
Correlation of body temperature with protection against staphylococcal enterotoxin B exposure and use in determining vaccine dose-schedule. Vaccine\| PubMed ID: 12798619	2003
Generation of protective immunity by inactivated recombinant staphylococcal enterotoxin B vaccine in nonhuman primates and identification of correlates of immunity. Clinical immunology (Orlando, Fla.)\| PubMed ID: 12865071	2003
Mutational effects on protein folding stability and antigenicity: the case of streptococcal pyrogenic exotoxin A. Clinical immunology (Orlando, Fla.)\| PubMed ID: 12865072	2003
Novel small molecule inhibitors of botulinum neurotoxin A metalloprotease activity. Biochemical and biophysical research communications\| PubMed ID: 14511652	2003
Ebola and Marburg viruses replicate in monocyte-derived dendritic cells without inducing the production of cytokines and full maturation. The Journal of infectious diseases\| PubMed ID: 14639532	2003
Ebola virus-like particles protect from lethal Ebola virus infection. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 14673108	2003
In vivo oligomerization and raft localization of Ebola virus protein VP40 during vesicular budding. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 14673115	2003
Identification of small molecule inhibitors of anthrax lethal factor. Nature structural & molecular biology\| PubMed ID: 14718925	2004
Generation of Marburg virus-like particles by co-expression of glycoprotein and matrix protein. FEMS immunology and medical microbiology\| PubMed ID: 14734183	2004
Time-lapse confocal imaging of development of Bacillus anthracis in macrophages. The Journal of infectious diseases\| PubMed ID: 15031802	2004
Role of natural killer cells in innate protection against lethal ebola virus infection. The Journal of experimental medicine\| PubMed ID: 15249592	2004
Ebola and Marburg virus-like particles activate human myeloid dendritic cells. Virology\| PubMed ID: 15302213	2004
Marburg virus-like particles protect guinea pigs from lethal Marburg virus infection. Vaccine\| PubMed ID: 15308377	2004
Conformational sampling of the botulinum neurotoxin serotype A light chain: implications for inhibitor binding. Bioorganic & medicinal chemistry\| PubMed ID: 15598556	2005
Purified Bacillus anthracis lethal toxin complex formed in vitro and during infection exhibits functional and biological activity. The Journal of biological chemistry\| PubMed ID: 15644338	2005
Lactobacilli activate human dendritic cells that skew T cells toward T helper 1 polarization. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15710900	2005
Human leukocyte antigen-DQ8 transgenic mice: a model to examine the toxicity of aerosolized staphylococcal enterotoxin B. Infection and immunity\| PubMed ID: 15784591	2005
Association of ebola virus matrix protein VP40 with microtubules. Journal of virology\| PubMed ID: 15795257	2005
The evolving field of biodefence: therapeutic developments and diagnostics. Nature reviews. Drug discovery\| PubMed ID: 15803193	2005
Virus-like particles exhibit potential as a pan-filovirus vaccine for both Ebola and Marburg viral infections. Vaccine\| PubMed ID: 15811650	2005
Dendritic cells endocytose Bacillus anthracis spores: implications for anthrax pathogenesis. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 15843553	2005
Analysis of Ebola virus and VLP release using an immunocapture assay. Journal of virological methods\| PubMed ID: 15893559	2005
An all-atom model of the pore-like structure of hexameric VP40 from Ebola: structural insights into the monomer-hexamer transition. Journal of structural biology\| PubMed ID: 15908231	2005
Induction of humoral and CD8+ T cell responses are required for protection against lethal Ebola virus infection. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 16002721	2005
Filovirus-like particles as vaccines and discovery tools. Expert review of vaccines\| PubMed ID: 16026254	2005
Anthrax biosensor, protective antigen ion channel asymmetric blockade. The Journal of biological chemistry\| PubMed ID: 16087661	2005
Persistence of zinc-binding bacterial superantigens at the surface of antigen-presenting cells contributes to the extreme potency of these superantigens as T-cell activators. Infection and immunity\| PubMed ID: 16113251	2005
Integrated bioassays in microfluidic devices: botulinum toxin assays. Journal of biomolecular screening\| PubMed ID: 16234350	2005
Reemergence of monkeypox: prevalence, diagnostics, and countermeasures. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America\| PubMed ID: 16288402	2005
Gene-specific countermeasures against Ebola virus based on antisense phosphorodiamidate morpholino oligomers. PLoS pathogens\| PubMed ID: 16415982	2006
VP35 knockdown inhibits Ebola virus amplification and protects against lethal infection in mice. Antimicrobial agents and chemotherapy\| PubMed ID: 16495261	2006
Conserved receptor-binding domains of Lake Victoria marburgvirus and Zaire ebolavirus bind a common receptor. The Journal of biological chemistry\| PubMed ID: 16595665	2006
Antisense treatments for biothreat agents. Current opinion in molecular therapeutics\| PubMed ID: 16610760	2006
Dominance of human innate immune responses in primary Francisella tularensis live vaccine strain vaccination. The Journal of allergy and clinical immunology\| PubMed ID: 16675351	2006
Passive immunotherapy of Bacillus anthracis pulmonary infection in mice with antisera produced by DNA immunization. Vaccine\| PubMed ID: 16790303	2006
Anthrax lethal toxin impairs innate immune functions of alveolar macrophages and facilitates Bacillus anthracis survival. Infection and immunity\| PubMed ID: 16926394	2006
Inhibition of metalloprotease botulinum serotype A from a pseudo-peptide binding mode to a small molecule that is active in primary neurons. The Journal of biological chemistry\| PubMed ID: 17092934	2007
Primary cultures of embryonic chicken neurons for sensitive cell-based assay of botulinum neurotoxin: implications for therapeutic discovery. Journal of biomolecular screening\| PubMed ID: 17332092	2007
Transcriptome analysis of human immune responses following live vaccine strain (LVS) Francisella tularensis vaccination. Molecular immunology\| PubMed ID: 17349694	2007
Chemical genetic screening identifies critical pathways in anthrax lethal toxin-induced pathogenesis. Chemistry & biology\| PubMed ID: 17379140	2007
NKp30-dependent cytolysis of filovirus-infected human dendritic cells. Cellular microbiology\| PubMed ID: 17381429	2007
A refined pharmacophore identifies potent 4-amino-7-chloroquinoline-based inhibitors of the botulinum neurotoxin serotype A metalloprotease. Journal of medicinal chemistry\| PubMed ID: 17417831	2007
Involvement of vacuolar protein sorting pathway in Ebola virus release independent of TSG101 interaction. The Journal of infectious diseases\| PubMed ID: 17940959	2007
Ebola virus inactivation with preservation of antigenic and structural integrity by a photoinducible alkylating agent. The Journal of infectious diseases\| PubMed ID: 17940961	2007
Filovirus-like particles produced in insect cells: immunogenicity and protection in rodents. The Journal of infectious diseases\| PubMed ID: 17940979	2007
Ebola virus-like particle-based vaccine protects nonhuman primates against lethal Ebola virus challenge. The Journal of infectious diseases\| PubMed ID: 17940980	2007
Development of a model for marburgvirus based on severe-combined immunodeficiency mice. Virology journal\| PubMed ID: 17961252	2007
Oligonucleotide antiviral therapeutics: antisense and RNA interference for highly pathogenic RNA viruses. Antiviral research\| PubMed ID: 18258313	2008
Functional CD8+ T cell responses in lethal Ebola virus infection. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 18322215	2008
Identification of oxidative stress and Toll-like receptor 4 signaling as a key pathway of acute lung injury. Cell\| PubMed ID: 18423196	2008
Monovalent virus-like particle vaccine protects guinea pigs and nonhuman primates against infection with multiple Marburg viruses. Expert review of vaccines\| PubMed ID: 18444889	2008
Novel 4-aminoquinolines active against chloroquine-resistant and sensitive P. falciparum strains that also inhibit botulinum serotype A. Journal of medicinal chemistry\| PubMed ID: 18637666	2008
Sizing the Bacillus anthracis PA63 channel with nonelectrolyte poly(ethylene glycols). Biophysical journal\| PubMed ID: 18645196	2008
A potent peptidomimetic inhibitor of botulinum neurotoxin serotype A has a very different conformation than SNAP-25 substrate. Structure (London, England : 1993)\| PubMed ID: 18940613	2008
Three-dimensional database mining identifies a unique chemotype that unites structurally diverse botulinum neurotoxin serotype A inhibitors in a three-zone pharmacophore. ChemMedChem\| PubMed ID: 19006141	2008
Chemical modifications of antisense morpholino oligomers enhance their efficacy against Ebola virus infection. Antimicrobial agents and chemotherapy\| PubMed ID: 19223614	2009
Reduced expression of CD45 protein-tyrosine phosphatase provides protection against anthrax pathogenesis. The Journal of biological chemistry\| PubMed ID: 19269962	2009
Development and characterization of a mouse model for Marburg hemorrhagic fever. Journal of virology\| PubMed ID: 19369350	2009
Filovirus infections. Journal of the American Veterinary Medical Association\| PubMed ID: 19405883	2009
Development of a broad-spectrum antiviral with activity against Ebola virus. Antiviral research\| PubMed ID: 19523489	2009
Novel broad-spectrum bis-(imidazolinylindole) derivatives with potent antibacterial activities against antibiotic-resistant strains. Antimicrobial agents and chemotherapy\| PubMed ID: 19635954	2009
Reduced levels of protein tyrosine phosphatase CD45 protect mice from the lethal effects of Ebola virus infection. Cell host & microbe\| PubMed ID: 19683682	2009
Discovery of common marburgvirus protective epitopes in a BALB/c mouse model. Virology journal\| PubMed ID: 19712478	2009
Generation of heterogeneous memory T cells by live attenuated tularemia vaccine in humans. Vaccine\| PubMed ID: 19799845	2009
Development of cell-based assays to measure botulinum neurotoxin serotype A activity using cleavage-sensitive antibodies. Journal of biomolecular screening\| PubMed ID: 19965805	2010
Mechanisms and consequences of ebolavirus-induced lymphocyte apoptosis. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 20028660	2010
Synthesis and biological evaluation of botulinum neurotoxin a protease inhibitors. Journal of medicinal chemistry\| PubMed ID: 20155918	2010
Efflux-mediated bis-indole resistance in Staphylococcus aureus reveals differential substrate specificities for MepA and MepR. Bioorganic & medicinal chemistry\| PubMed ID: 20188576	2010
Ebola virus uses clathrin-mediated endocytosis as an entry pathway. Virology\| PubMed ID: 20202662	2010
Gaining ground: assays for therapeutics against botulinum neurotoxin. Trends in microbiology\| PubMed ID: 20202845	2010
Antiviral activity of a small-molecule inhibitor of filovirus infection. Antimicrobial agents and chemotherapy\| PubMed ID: 20211898	2010
Iterative structure-based peptide-like inhibitor design against the botulinum neurotoxin serotype A. PloS one\| PubMed ID: 20614028	2010
3D visualization of HIV transfer at the virological synapse between dendritic cells and T cells. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 20624966	2010
Comparative in vitro activity profiles of novel bis-indole antibacterials against gram-positive and gram-negative clinical isolates. Antimicrobial agents and chemotherapy\| PubMed ID: 20625154	2010
Development of high-content imaging assays for lethal viral pathogens. Journal of biomolecular screening\| PubMed ID: 20639507	2010
Infectious Lassa virus, but not filoviruses, is restricted by BST-2/tetherin. Journal of virology\| PubMed ID: 20686043	2010
Identification of essential filovirion-associated host factors by serial proteomic analysis and RNAi screen. Molecular & cellular proteomics : MCP\| PubMed ID: 20702783	2010
The rapidly advancing field of biodefense benefits many other, critical public health concerns. Discovery medicine\| PubMed ID: 20704875	2005
The osmolyte trimethylamine N-oxide (TMAO) increases the proteolytic activity of botulinum neurotoxin light chains A, B, and E: implications for enhancing analytical assay sensitivity. Journal of biomolecular screening\| PubMed ID: 20720092	2010
Advanced antisense therapies for postexposure protection against lethal filovirus infections. Nature medicine\| PubMed ID: 20729866	2010
Assembly of a functional Machupo virus polymerase complex. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 20978208	2010
Analysis of Botulinum Neurotoxin Serotype A Metalloprotease Inhibitors: Analogs of a Chemotype for Therapeutic Development in the Context of a Three-Zone Pharmacophore. Open access bioinformatics\| PubMed ID: 21103387	2010
Pharmacophore Refinement Guides the Rational Design of Nanomolar-Range Inhibitors of the Botulinum Neurotoxin Serotype A Metalloprotease. ACS medicinal chemistry letters\| PubMed ID: 21116458	2010
Alkylated porphyrins have broad antiviral activity against hepadnaviruses, flaviviruses, filoviruses, and arenaviruses. Antimicrobial agents and chemotherapy\| PubMed ID: 21135183	2011
Generation and characterization of high affinity human monoclonal antibodies that neutralize staphylococcal enterotoxin B. Journal of immune based therapies and vaccines\| PubMed ID: 21176153	2010
Distinct patterns of IFITM-mediated restriction of filoviruses, SARS coronavirus, and influenza A virus. PLoS pathogens\| PubMed ID: 21253575	2011
A chemotype that inhibits three unrelated pathogenic targets: the botulinum neurotoxin serotype A light chain, P. falciparum malaria, and the Ebola filovirus. Journal of medicinal chemistry\| PubMed ID: 21265542	2011
Identification of a small-molecule entry inhibitor for filoviruses. Journal of virology\| PubMed ID: 21270170	2011
Key genomic changes necessary for an in vivo lethal mouse marburgvirus variant selection process. Journal of virology\| PubMed ID: 21289122	2011
Ebola virus glycoprotein Fc fusion protein confers protection against lethal challenge in vaccinated mice. Vaccine\| PubMed ID: 21329775	2011
Embryonic stem cell-derived motoneurons provide a highly sensitive cell culture model for botulinum neurotoxin studies, with implications for high-throughput drug discovery. Stem cell research\| PubMed ID: 21353660	2011
Crimean-Congo hemorrhagic fever: current and future prospects of vaccines and therapies. Antiviral research\| PubMed ID: 21362441	2011
Inhibition of Ebola virus entry by a C-peptide targeted to endosomes. The Journal of biological chemistry\| PubMed ID: 21454542	2011
Development and characterization of rabbit and mouse antibodies against ebolavirus envelope glycoproteins. Journal of virological methods\| PubMed ID: 21513741	2011
Filovirus vaccines. Human vaccines\| PubMed ID: 21519188	2011
A STAT-1 knockout mouse model for Machupo virus pathogenesis. Virology journal\| PubMed ID: 21672221	2011
Ebolavirus delta-peptide immunoadhesins inhibit marburgvirus and ebolavirus cell entry. Journal of virology\| PubMed ID: 21697477	2011
Machupo virus glycoprotein determinants for human transferrin receptor 1 binding and cell entry. PloS one\| PubMed ID: 21750710	2011
Correlates of immunity to filovirus infection. Viruses\| PubMed ID: 21994766	2011
Identification of an antioxidant small-molecule with broad-spectrum antiviral activity. Antiviral research\| PubMed ID: 22027648	2012
Post-intoxication inhibition of botulinum neurotoxin serotype A within neurons by small-molecule, non-peptidic inhibitors. Toxins\| PubMed ID: 22069707	2011
Evaluation of perceived threat differences posed by filovirus variants. Biosecurity and bioterrorism : biodefense strategy, practice, and science\| PubMed ID: 22070137	2011
Time-dependent botulinum neurotoxin serotype A metalloprotease inhibitors. Bioorganic & medicinal chemistry\| PubMed ID: 22082667	2011
Humanized mice as a preclinical tool for infectious disease and biomedical research. Annals of the New York Academy of Sciences\| PubMed ID: 22211979	2011
Advanced morpholino oligomers: a novel approach to antiviral therapy. Antiviral research\| PubMed ID: 22353544	2012
The synthesis of 2,5-bis(4-amidinophenyl)thiophene derivatives providing submicromolar-range inhibition of the botulinum neurotoxin serotype A metalloprotease. European journal of medicinal chemistry\| PubMed ID: 22516424	2012
Drug discovery technologies and strategies for Machupo virus and other New World arenaviruses. Expert opinion on drug discovery\| PubMed ID: 22607481	2012
Nonhuman primates as models for the discovery and development of ebolavirus therapeutics. Expert opinion on drug discovery\| PubMed ID: 22647202	2011
Assembly of Ebola virus matrix protein VP40 is regulated by latch-like properties of N and C terminal tails. PloS one\| PubMed ID: 22792204	2012
Therapeutics for filovirus infection: traditional approaches and progress towards in silico drug design. Expert opinion on drug discovery\| PubMed ID: 22873527	2012
High-throughput screen using a single-cell tyrosine phosphatase assay reveals biologically active inhibitors of tyrosine phosphatase CD45. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 22891353	2012
The International Code of Virus Classification and Nomenclature (ICVCN): proposal to delete Rule 3.41. Archives of virology\| PubMed ID: 22932924	2013
Peptide conjugated phosphorodiamidate morpholino oligomers increase survival of mice challenged with Ames Bacillus anthracis. Nucleic acid therapeutics\| PubMed ID: 22978365	2012
Virus nomenclature below the species level: a standardized nomenclature for natural variants of viruses assigned to the family Filoviridae. Archives of virology\| PubMed ID: 23001720	2013
A limited structural modification results in a significantly more efficacious diazachrysene-based filovirus inhibitor. Viruses\| PubMed ID: 23012625	2012
Shedding light on filovirus infection with high-content imaging. Viruses\| PubMed ID: 23012631	2012
Bis-imidazolinylindoles are active against methicillin-resistant Staphylococcus aureus and multidrug-resistant Mycobacterium tuberculosis. The Journal of antibiotics\| PubMed ID: 23149517	2013
High content image based analysis identifies cell cycle inhibitors as regulators of Ebola virus infection. Viruses\| PubMed ID: 23202445	2012
Discovery and early development of AVI-7537 and AVI-7288 for the treatment of Ebola virus and Marburg virus infections. Viruses\| PubMed ID: 23202506	2012
Novel Benzimidazole Inhibitors of Botulinum Neurotoxin/A Display Enzyme and Cell-Based Potency. The botulinum journal\| PubMed ID: 23205055	2011
Ebola virus genome plasticity as a marker of its passaging history: a comparison of in vitro passaging to non-human primate infection. PloS one\| PubMed ID: 23209706	2012
Standardization of the filovirus plaque assay for use in preclinical studies. Viruses\| PubMed ID: 23223188	2012
The impact of regulations, safety considerations and physical limitations on research progress at maximum biocontainment. Viruses\| PubMed ID: 23342380	2012
Virus nomenclature below the species level: a standardized nomenclature for laboratory animal-adapted strains and variants of viruses assigned to the family Filoviridae. Archives of virology\| PubMed ID: 23358612	2013
Integrating high-content imaging and chemical genetics to probe host cellular pathways critical for yersinia pestis infection. PloS one\| PubMed ID: 23383093	2013
Characterization of a putative filovirus vaccine: virus-like particles. Virologica Sinica\| PubMed ID: 23385315	2013
The International Code of Virus Classification and Nomenclature (ICVCN): proposal for text changes for improved differentiation of viral taxa and viruses. Archives of virology\| PubMed ID: 23417351	2013
Predictive systems biology approach to broad-spectrum, host-directed drug target discovery in infectious diseases. Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing\| PubMed ID: 23424108	2013
A systematic screen of FDA-approved drugs for inhibitors of biological threat agents. PloS one\| PubMed ID: 23577127	2013
Small molecule inhibitors of ER α-glucosidases are active against multiple hemorrhagic fever viruses. Antiviral research\| PubMed ID: 23578725	2013
IFITM-2 and IFITM-3 but not IFITM-1 restrict Rift Valley fever virus. Journal of virology\| PubMed ID: 23720721	2013
The C terminus of the catalytic domain of type A botulinum neurotoxin may facilitate product release from the active site. The Journal of biological chemistry\| PubMed ID: 23779108	2013
Crimean-Congo hemorrhagic fever virus utilizes a clathrin- and early endosome-dependent entry pathway. Virology\| PubMed ID: 23791227	2013
4-Amino-7-chloroquinolines: probing ligand efficiency provides botulinum neurotoxin serotype A light chain inhibitors with significant antiprotozoal activity. Journal of medicinal chemistry\| PubMed ID: 23815186	2013
Characterization of the Burkholderia thailandensis SOS response by using whole-transcriptome shotgun sequencing. Applied and environmental microbiology\| PubMed ID: 23872555	2013
Anthrax toxin-induced rupture of artificial lipid bilayer membranes. The Journal of chemical physics\| PubMed ID: 23947891	2013
Ebola virus-like particles stimulate type I interferons and proinflammatory cytokine expression through the toll-like receptor and interferon signaling pathways. Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research\| PubMed ID: 24102579	2014
Nonhuman transferrin receptor 1 is an efficient cell entry receptor for Ocozocoautla de Espinosa virus. Journal of virology\| PubMed ID: 24109228	2013
Virus nomenclature below the species level: a standardized nomenclature for filovirus strains and variants rescued from cDNA. Archives of virology\| PubMed ID: 24190508	2014
Potent and broad-spectrum antibacterial activity of indole-based bisamidine antibiotics: synthesis and SAR of novel analogs of MBX 1066 and MBX 1090. Bioorganic & medicinal chemistry\| PubMed ID: 24239389	2013
Reactive oxygen species activate NFκB (p65) and p53 and induce apoptosis in RVFV infected liver cells. Virology\| PubMed ID: 24418562	2014
Recent developments in cell-based assays and stem cell technologies for botulinum neurotoxin research and drug discovery. Expert review of molecular diagnostics\| PubMed ID: 24450833	2014
Alveolar macrophages infected with Ames or Sterne strain of Bacillus anthracis elicit differential molecular expression patterns. PloS one\| PubMed ID: 24516547	2014
Toll-like receptor agonist augments virus-like particle-mediated protection from Ebola virus with transient immune activation. PloS one\| PubMed ID: 24586996	2014
Protection against filovirus diseases by a novel broad-spectrum nucleoside analogue BCX4430. Nature\| PubMed ID: 24590073	2014
TrkA in vivo function is negatively regulated by ubiquitination. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 24623787	2014
Marburgvirus hijacks nrf2-dependent pathway by targeting nrf2-negative regulator keap1. Cell reports\| PubMed ID: 24630992	2014
Induced IL-10 splice altering approach to antiviral drug discovery. Nucleic acid therapeutics\| PubMed ID: 24655055	2014
Second generation steroidal 4-aminoquinolines are potent, dual-target inhibitors of the botulinum neurotoxin serotype A metalloprotease and P. falciparum malaria. Journal of medicinal chemistry\| PubMed ID: 24742203	2014
A high-content imaging assay for the quantification of the Burkholderia pseudomallei induced multinucleated giant cell (MNGC) phenotype in murine macrophages. BMC microbiology\| PubMed ID: 24750902	2014
Multi-faceted proteomic characterization of host protein complement of Rift Valley fever virus virions and identification of specific heat shock proteins, including HSP90, as important viral... PloS one\| PubMed ID: 24809507	2014
Applications of In Vivo Imaging in the Evaluation of the Pathophysiology of Viral and Bacterial Infections and in Development of Countermeasures to BSL3/4 Pathogens. Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging\| PubMed ID: 25008802	2014
HSPA5 is an essential host factor for Ebola virus infection. Antiviral research\| PubMed ID: 25017472	2014
High content image-based screening of a protease inhibitor library reveals compounds broadly active against Rift Valley fever virus and other highly pathogenic RNA viruses. PLoS neglected tropical diseases\| PubMed ID: 25144302	2014
Filovirus RefSeq entries: evaluation and selection of filovirus type variants, type sequences, and names. Viruses\| PubMed ID: 25256396	2014
Vaccine adjuvant uses of poly-IC and derivatives. Expert review of vaccines\| PubMed ID: 25308798	2014
Recent Advances in Botulinum Neurotoxin Inhibitor Development. Current topics in medicinal chemistry\| PubMed ID: 25335887	2014
High-Content Image-Based Screening of a Signal Transduction Pathway Inhibitor Small-Molecule Library against Highly Pathogenic RNA Viruses. Journal of biomolecular screening\| PubMed ID: 25342145	2014