Asrar B. Malik

Department of Pharmacology, University of Illinois at Chicago

Affiliated withUniversity of Illinois at Chicago

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 12	2014

Other Publications

Article	Year
Toll-like receptor-4 (TLR4) signaling augments chemokine-induced neutrophil migration by modulating cell surface expression of chemokine receptors. Nature medicine\| PubMed ID: 12592402	2003
Role of neutrophil NADPH oxidase in the mechanism of tumor necrosis factor-alpha -induced NF-kappa B activation and intercellular adhesion molecule-1 expression in endothelial cells. The Journal of biological chemistry\| PubMed ID: 11729200	2002
Albumin transcytosis in mesothelium: further evidence of a transcellular pathway in polarized cells. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 11741809	2002
Protein kinase C-delta (PKC-delta ) is activated by type I interferons and mediates phosphorylation of Stat1 on serine 727. The Journal of biological chemistry\| PubMed ID: 11839738	2002
Time-dependent reversal of sepsis-induced PMN uptake and lung vascular injury by expression of CD18 antagonist. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 11880306	2002
Modulatory role of focal adhesion kinase in regulating human pulmonary arterial endothelial barrier function. The Journal of physiology\| PubMed ID: 11897849	2002
Vesicle formation and trafficking in endothelial cells and regulation of endothelial barrier function. Histochemistry and cell biology\| PubMed ID: 11935286	2002
Role of NADPH oxidase in the mechanism of lung neutrophil sequestration and microvessel injury induced by Gram-negative sepsis: studies in p47phox-/- and gp91phox-/- mice. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 11937554	2002
PKCzeta regulates TNF-alpha-induced activation of NADPH oxidase in endothelial cells. Circulation research\| PubMed ID: 12016268	2002
Thrombin receptors activate G(o) proteins in endothelial cells to regulate intracellular calcium and cell shape changes. The Journal of biological chemistry\| PubMed ID: 12039967	2002
Impairment of store-operated Ca2+ entry in TRPC4(-/-) mice interferes with increase in lung microvascular permeability. Circulation research\| PubMed ID: 12114324	2002
Nitric oxide stimulates macrophage inflammatory protein-2 expression in sepsis. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 12165537	2002
Galpha(q) and Gbetagamma regulate PAR-1 signaling of thrombin-induced NF-kappaB activation and ICAM-1 transcription in endothelial cells. Circulation research\| PubMed ID: 12215488	2002
Transport of nitrated albumin across continuous vascular endothelium. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12370442	2002
Quantitative analysis of albumin uptake and transport in the rat microvessel endothelial monolayer. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 12471015	2003
Protein transport across the lung epithelial barrier. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 12533309	2003
VE-cadherin-induced Cdc42 signaling regulates formation of membrane protrusions in endothelial cells. The Journal of biological chemistry\| PubMed ID: 12595527	2003
Tumor necrosis factor-alpha induces early-onset endothelial adhesivity by protein kinase Czeta-dependent activation of intercellular adhesion molecule-1. Circulation research\| PubMed ID: 12714560	2003
Protein kinase C modifications of VE-cadherin, p120, and beta-catenin contribute to endothelial barrier dysregulation induced by thrombin. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 12740216	2003
Role of Ca2+ signaling in the regulation of endothelial permeability. Vascular pharmacology\| PubMed ID: 12747958	2002
Protein kinase Calpha-induced p115RhoGEF phosphorylation signals endothelial cytoskeletal rearrangement. The Journal of biological chemistry\| PubMed ID: 12754211	2003
RhoA interaction with inositol 1,4,5-trisphosphate receptor and transient receptor potential channel-1 regulates Ca2+ entry. Role in signaling increased endothelial permeability. The Journal of biological chemistry\| PubMed ID: 12766172	2003
Two waves of platelet secretion induced by thromboxane A2 receptor and a critical role for phosphoinositide 3-kinases. The Journal of biological chemistry\| PubMed ID: 12796499	2003
E. coli pneumonia induces CD18-independent airway neutrophil migration in the absence of increased lung vascular permeability. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 12818890	2003
Tumor necrosis factor-alpha induces nuclear factor-kappaB-dependent TRPC1 expression in endothelial cells. The Journal of biological chemistry\| PubMed ID: 12855710	2003
Intersectin regulates fission and internalization of caveolae in endothelial cells. Molecular biology of the cell\| PubMed ID: 12960435	2003
TLR4 signaling induces TLR2 expression in endothelial cells via neutrophil NADPH oxidase. The Journal of clinical investigation\| PubMed ID: 14561708	2003
Caveolin regulation of endothelial function. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 14604847	2003
Oxidant signaling in lung cells. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 14656698	2004
Cdc42 regulates the restoration of endothelial barrier function. Circulation research\| PubMed ID: 14656933	2004
Albumin endocytosis in endothelial cells induces TGF-beta receptor II signaling. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 14729511	2004
Role of Src-induced dynamin-2 phosphorylation in caveolae-mediated endocytosis in endothelial cells. The Journal of biological chemistry\| PubMed ID: 15007081	2004
Protein kinase Calpha phosphorylates the TRPC1 channel and regulates store-operated Ca2+ entry in endothelial cells. The Journal of biological chemistry\| PubMed ID: 15016832	2004
Albumin mediates the transcytosis of myeloperoxidase by means of caveolae in endothelial cells. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15136724	2004
cAMP targeting of p38 MAP kinase inhibits thrombin-induced NF-kappaB activation and ICAM-1 expression in endothelial cells. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 15246972	2004
Gbetagamma activation of Src induces caveolae-mediated endocytosis in endothelial cells. The Journal of biological chemistry\| PubMed ID: 15345719	2004
Tumor necrosis factor-alpha-induced TRPC1 expression amplifies store-operated Ca2+ influx and endothelial permeability. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 15347566	2004
Functional and morphological studies of protein transcytosis in continuous endothelia. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 15475492	2004
RNA interference targeting transforming growth factor-beta type II receptor suppresses ocular inflammation and fibrosis. Molecular vision\| PubMed ID: 15475878	2004
Integrated control of lung fluid balance. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 15531757	2004
SHIP2 is recruited to the cell membrane upon macrophage colony-stimulating factor (M-CSF) stimulation and regulates M-CSF-induced signaling. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 15557176	2004
RhoA/Rho-associated kinase pathway selectively regulates thrombin-induced intercellular adhesion molecule-1 expression in endothelial cells via activation of I kappa B kinase beta and phosph... Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 15557193	2004
LPS activation of Toll-like receptor 4 signals CD11b/CD18 expression in neutrophils. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 15563689	2005
Protease-activated receptor-1 activation of endothelial cells induces protein kinase Calpha-dependent phosphorylation of syntaxin 4 and Munc18c: role in signaling p-selectin expression. The Journal of biological chemistry\| PubMed ID: 15576373	2005
Sphingosine 1-phosphate-induced mobilization of intracellular Ca2+ mediates rac activation and adherens junction assembly in endothelial cells. The Journal of biological chemistry\| PubMed ID: 15728185	2005
Lysophosphatidylcholine modulates neutrophil oxidant production through elevation of cyclic AMP. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 15728511	2005
Inactivation of CD11b in a mouse transgenic model protects against sepsis-induced lung PMN infiltration and vascular injury. Physiological genomics\| PubMed ID: 15831844	2005
Angiopoietin-1 opposes VEGF-induced increase in endothelial permeability by inhibiting TRPC1-dependent Ca2 influx. Circulation research\| PubMed ID: 15920022	2005
G alpha12 interaction with alphaSNAP induces VE-cadherin localization at endothelial junctions and regulates barrier function. The Journal of biological chemistry\| PubMed ID: 15980433	2005
Functional role of TRPC channels in the regulation of endothelial permeability. Pflügers Archiv : European journal of physiology\| PubMed ID: 15988589	2005
Constitutive eNOS-derived nitric oxide is a determinant of endothelial junctional integrity. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 16093363	2005
Cholesterol-dependent syntaxin-4 and SNAP-23 clustering regulates caveolar fusion with the endothelial plasma membrane. The Journal of biological chemistry\| PubMed ID: 16118213	2005
siRNA-induced caveolin-1 knockdown in mice increases lung vascular permeability via the junctional pathway. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 16183667	2006
Role of phosphatidylinositol 3-kinase-gamma in mediating lung neutrophil sequestration and vascular injury induced by E. coli sepsis. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 16183669	2005
Suppression of RhoA activity by focal adhesion kinase-induced activation of p190RhoGAP: role in regulation of endothelial permeability. The Journal of biological chemistry\| PubMed ID: 16308318	2006
Cdc42 regulates adherens junction stability and endothelial permeability by inducing alpha-catenin interaction with the vascular endothelial cadherin complex. Circulation research\| PubMed ID: 16322481	2006
Cellular and molecular biology for intensivists: a primer--endothelial cells. Critical care medicine\| PubMed ID: 16340438	2005
Signaling mechanisms regulating endothelial permeability. Physiological reviews\| PubMed ID: 16371600	2006
Phosphatidylinositol 3-kinase gamma signaling through protein kinase Czeta induces NADPH oxidase-mediated oxidant generation and NF-kappaB activation in endothelial cells. The Journal of biological chemistry\| PubMed ID: 16527821	2006
NF-kappa B activation as a pathological mechanism of septic shock and inflammation. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 16531564	2006
Ca2+ influx induced by protease-activated receptor-1 activates a feed-forward mechanism of TRPC1 expression via nuclear factor-kappaB activation in endothelial cells. The Journal of biological chemistry\| PubMed ID: 16709572	2006
De novo ICAM-1 synthesis in the mouse lung: model of assessment of protein expression in lungs. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 16714332	2006
Regulation of lung neutrophil recruitment by VE-cadherin. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 16782751	2006
Caveolin-1 regulates store-operated Ca2+ influx by binding of its scaffolding domain to transient receptor potential channel-1 in endothelial cells. Molecular pharmacology\| PubMed ID: 16822931	2006
p38 MAPK activation coupled to endocytosis is a determinant of endothelial monolayer integrity. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 16891390	2007
Endothelial cell-restricted disruption of FoxM1 impairs endothelial repair following LPS-induced vascular injury. The Journal of clinical investigation\| PubMed ID: 16955137	2006
Novel mechanism of endothelial nitric oxide synthase activation mediated by caveolae internalization in endothelial cells. Circulation research\| PubMed ID: 16973909	2006
Caveolin-1 regulates NF-kappaB activation and lung inflammatory response to sepsis induced by lipopolysaccharide. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 16982927	2006
Ca2+ signaling, TRP channels, and endothelial permeability. Microcirculation (New York, N.Y. : 1994)\| PubMed ID: 17085428	2006
Blockade of class IA phosphoinositide 3-kinase in neutrophils prevents NADPH oxidase activation- and adhesion-dependent inflammation. The Journal of biological chemistry\| PubMed ID: 17197441	2007
Galphaq-TRPC6-mediated Ca2+ entry induces RhoA activation and resultant endothelial cell shape change in response to thrombin. The Journal of biological chemistry\| PubMed ID: 17197445	2007
Myocardium defects and ventricular hypoplasia in mice homozygous null for the Forkhead Box M1 transcription factor. Developmental dynamics : an official publication of the American Association of Anatomists\| PubMed ID: 17366632	2007
Protease-activated receptor-3 (PAR3) regulates PAR1 signaling by receptor dimerization. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17376866	2007
Intersectin-1s regulates the mitochondrial apoptotic pathway in endothelial cells. The Journal of biological chemistry\| PubMed ID: 17405881	2007
RhoGDI-1 modulation of the activity of monomeric RhoGTPase RhoA regulates endothelial barrier function in mouse lungs. Circulation research\| PubMed ID: 17525371	2007
Cdc42 regulates the restoration of endothelial adherens junctions and permeability. Trends in cardiovascular medicine\| PubMed ID: 17574122	2007
Regulation of cyclooxygenase-2 expression by small GTPase Rac2 in bone marrow macrophages. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 17575012	2007
Interrelations/cross talk between transcellular transport function and paracellular tight junctional properties in lung epithelial and endothelial barriers. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 17601795	2007
E3 ubiquitin ligase Cblb regulates the acute inflammatory response underlying lung injury. Nature medicine\| PubMed ID: 17618294	2007
GDI-1 phosphorylation switch at serine 96 induces RhoA activation and increased endothelial permeability. Molecular and cellular biology\| PubMed ID: 17636025	2007
Molecular determinants of endothelial transcytosis and their role in endothelial permeability. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 17644753	2007
Neutrophil caveolin-1 expression contributes to mechanism of lung inflammation and injury. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 17993589	2008
Dual regulation of endothelial junctional permeability. Science's STKE : signal transduction knowledge environment\| PubMed ID: 18000237	2007
Role of TRPM2 channel in mediating H2O2-induced Ca2+ entry and endothelial hyperpermeability. Circulation research\| PubMed ID: 18048770	2008
Role of NF-kappaB-dependent caveolin-1 expression in the mechanism of increased endothelial permeability induced by lipopolysaccharide. The Journal of biological chemistry\| PubMed ID: 18077459	2008
Increased pulmonary vascular resistance and defective pulmonary artery filling in caveolin-1-/- mice. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 18192592	2008
Regulation of endothelial junctional permeability. Annals of the New York Academy of Sciences\| PubMed ID: 18375586	2008
Augmented inducible nitric oxide synthase expression and increased NO production reduce sepsis-induced lung injury and mortality in myeloperoxidase-null mice. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 18424617	2008
Intercellular adhesion molecule-1-dependent neutrophil adhesion to endothelial cells induces caveolae-mediated pulmonary vascular hyperpermeability. Circulation research\| PubMed ID: 18511851	2008
Critical role of Cdc42 in mediating endothelial barrier protection in vivo. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 18515405	2008
Nonmuscle myosin light-chain kinase mediates neutrophil transmigration in sepsis-induced lung inflammation by activating beta2 integrins. Nature immunology\| PubMed ID: 18587400	2008
NADPH oxidase-dependent signaling in endothelial cells: role in physiology and pathophysiology. Antioxidants & redox signaling\| PubMed ID: 18783313	2009
FGF signaling preserves the integrity of endothelial adherens junctions. Developmental cell\| PubMed ID: 18804429	2008
Activation of sphingosine kinase-1 reverses the increase in lung vascular permeability through sphingosine-1-phosphate receptor signaling in endothelial cells. Circulation research\| PubMed ID: 18849324	2008
Ca2+ entry via TRPC channels is necessary for thrombin-induced NF-kappaB activation in endothelial cells through AMP-activated protein kinase and protein kinase Cdelta. The Journal of biological chemistry\| PubMed ID: 18990707	2009
Caveolin-1 scaffold domain interacts with TRPC1 and IP3R3 to regulate Ca2+ store release-induced Ca2+ entry in endothelial cells. American journal of physiology. Cell physiology\| PubMed ID: 19052258	2009
Tiam1 and Rac1 are required for platelet-activating factor-induced endothelial junctional disassembly and increase in vascular permeability. The Journal of biological chemistry\| PubMed ID: 19095647	2009
Role of H(2)O(2)-activated TRPM2 calcium channel in oxidant-induced endothelial injury. Thrombosis and haemostasis\| PubMed ID: 19350103	2009
NF-kappaB regulates thrombin-induced ICAM-1 gene expression in cooperation with NFAT by binding to the intronic NF-kappaB site in the ICAM-1 gene. Physiological genomics\| PubMed ID: 19351910	2009
Persistent eNOS activation secondary to caveolin-1 deficiency induces pulmonary hypertension in mice and humans through PKG nitration. The Journal of clinical investigation\| PubMed ID: 19487814	2009
Lipopolysaccharide stimulates platelet secretion and potentiates platelet aggregation via TLR4/MyD88 and the cGMP-dependent protein kinase pathway. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 19494325	2009
Intersectin-2L regulates caveola endocytosis secondary to Cdc42-mediated actin polymerization. The Journal of biological chemistry\| PubMed ID: 19622753	2009
LIM kinase 1 promotes endothelial barrier disruption and neutrophil infiltration in mouse lungs. Circulation research\| PubMed ID: 19679840	2009
Bone marrow progenitor cells induce endothelial adherens junction integrity by sphingosine-1-phosphate-mediated Rac1 and Cdc42 signaling. Circulation research\| PubMed ID: 19696411	2009
A non-redundant role for MKP5 in limiting ROS production and preventing LPS-induced vascular injury. The EMBO journal\| PubMed ID: 19696743	2009
Toll-like receptor 4 mediates neutrophil sequestration and lung injury induced by endotoxin and hyperinflation. Critical care medicine\| PubMed ID: 19789446	2010
Requirement of alpha(4)beta(1) and alpha(5)beta(1) integrin expression in bone-marrow-derived progenitor cells in preventing endotoxin-induced lung vascular injury and edema in mice. Stem cells (Dayton, Ohio)\| PubMed ID: 19839056	2009
Bone marrow-derived progenitor cells prevent thrombin-induced increase in lung vascular permeability. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 19880506	2010
Size and dynamics of caveolae studied using nanoparticles in living endothelial cells. ACS nano\| PubMed ID: 19919048	2009
Requisite role of the cholinergic alpha7 nicotinic acetylcholine receptor pathway in suppressing Gram-negative sepsis-induced acute lung inflammatory injury. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 19949071	2010
Ca2+ influx via TRPC channels induces NF-kappaB-dependent A20 expression to prevent thrombin-induced apoptosis in endothelial cells. American journal of physiology. Cell physiology\| PubMed ID: 20032510	2010
TRP channels and the control of vascular function. Current opinion in pharmacology\| PubMed ID: 20060363	2010
Lipid phosphate phosphatase 3 stabilization of beta-catenin induces endothelial cell migration and formation of branching point structures. Molecular and cellular biology\| PubMed ID: 20123964	2010
Regulation of endothelial permeability via paracellular and transcellular transport pathways. Annual review of physiology\| PubMed ID: 20148685	2010
TRPM2 channel regulates endothelial barrier function. Advances in experimental medicine and biology\| PubMed ID: 20204729	2010
A novel function of sphingosine kinase 1 suppression of JNK activity in preventing inflammation and injury. The Journal of biological chemistry\| PubMed ID: 20299461	2010
Caveolin-1 deficiency dampens Toll-like receptor 4 signaling through eNOS activation. The American journal of pathology\| PubMed ID: 20304961	2010
A novel insight into the mechanism of pulmonary hypertension involving caveolin-1 deficiency and endothelial nitric oxide synthase activation. Trends in cardiovascular medicine\| PubMed ID: 20382348	2009
Role of protein kinase Czeta in thrombin-induced RhoA activation and inter-endothelial gap formation of human dermal microvessel endothelial cell monolayers. Microvascular research\| PubMed ID: 20417648	2010
FoxM1 regulates re-annealing of endothelial adherens junctions through transcriptional control of beta-catenin expression. The Journal of experimental medicine\| PubMed ID: 20660612	2010
Kruppel-like factor-4 transcriptionally regulates VE-cadherin expression and endothelial barrier function. Circulation research\| PubMed ID: 20724706	2010
NANOG induction of fetal liver kinase-1 (FLK1) transcription regulates endothelial cell proliferation and angiogenesis. Blood\| PubMed ID: 21119109	2011
Regulation of dynamin-2 assembly-disassembly and function through the SH3A domain of intersectin-1s. Journal of cellular and molecular medicine\| PubMed ID: 21129155	2011
Interaction of a specific population of human embryonic stem cell-derived progenitor cells with CD11b+ cells ameliorates sepsis-induced lung inflammatory injury. The American journal of pathology\| PubMed ID: 21224068	2011
Innate immune function of the adherens junction protein p120-catenin in endothelial response to endotoxin. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 21278343	2011
Src phosphorylation of endothelial cell surface intercellular adhesion molecule-1 mediates neutrophil adhesion and contributes to the mechanism of lung inflammation. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 21474822	2011
Role of endothelial injury in disease mechanisms and contribution of progenitor cells in mediating endothelial repair. Immunobiology\| PubMed ID: 21513999	2012
Caveolin-1-eNOS signaling promotes p190RhoGAP-A nitration and endothelial permeability. The Journal of cell biology\| PubMed ID: 21624953	2011
FoxM1 mediates the progenitor function of type II epithelial cells in repairing alveolar injury induced by Pseudomonas aeruginosa. The Journal of experimental medicine\| PubMed ID: 21708928	2011
Delivery of nanoparticle: complexed drugs across the vascular endothelial barrier via caveolae. IUBMB life\| PubMed ID: 21766412	2011
Improvement of cardiac function in mouse myocardial infarction after transplantation of epigenetically-modified bone marrow progenitor cells. PloS one\| PubMed ID: 21799893	2011
Permeability of endothelial barrier: cell culture and in vivo models. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 21874463	2011
The redox-sensitive cation channel TRPM2 modulates phagocyte ROS production and inflammation. Nature immunology\| PubMed ID: 22101731	2012
The Ca(2+) sensor stromal interaction molecule 1 (STIM1) is necessary and sufficient for the store-operated Ca(2+) entry function of transient receptor potential canonical (TRPC) 1 and 4 cha... Molecular pharmacology\| PubMed ID: 22210847	2012
Nitric oxide-dependent Src activation and resultant caveolin-1 phosphorylation promote eNOS/caveolin-1 binding and eNOS inhibition. Molecular biology of the cell\| PubMed ID: 22323292	2012
Sphingosine kinase 1 mediation of expression of the anaphylatoxin receptor C5L2 dampens the inflammatory response to endotoxin. PloS one\| PubMed ID: 22355325	2012
Bidirectional regulation of neutrophil migration by mitogen-activated protein kinases. Nature immunology\| PubMed ID: 22447027	2012
PKCα activation of p120-catenin serine 879 phospho-switch disassembles VE-cadherin junctions and disrupts vascular integrity. Circulation research\| PubMed ID: 22798526	2012
ICAM-1-activated Src and eNOS signaling increase endothelial cell surface PECAM-1 adhesivity and neutrophil transmigration. Blood\| PubMed ID: 22806890	2012
A Critical Role for P-Rex1 in Endothelial Junction Disruption and Vascular Hyper-Permeability. Circulation research\| PubMed ID: 22965143	2012
TLR4 activation of TRPC6-dependent calcium signaling mediates endotoxin-induced lung vascular permeability and inflammation. The Journal of experimental medicine\| PubMed ID: 23045603	2012
VE-Cadherin Signaling Induces EB3 Phosphorylation to Suppress Microtubule Growth and Assemble Adherens Junctions. Molecular cell\| PubMed ID: 23159740	2012
Nanoparticles squeezing across the blood-endothelial barrier via caveolae. Therapeutic delivery\| PubMed ID: 23343150	2013
Activation of NLRP3 inflammasome in alveolar macrophages contributes to mechanical stretch-induced lung inflammation and injury. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 23436933	2013
Bioluminescent detection of peroxynitrite with a boronic acid-caged luciferin. Free radical biology & medicine\| PubMed ID: 23474271	2013
Store-operated Ca2+ entry (SOCE) induced by protease-activated receptor-1 mediates STIM1 protein phosphorylation to inhibit SOCE in endothelial cells through AMP-activated protein kinase and... The Journal of biological chemistry\| PubMed ID: 23625915	2013
Transcriptional regulation of endothelial cell and vascular development. Circulation research\| PubMed ID: 23661712	2013
Cytoskeletal dynamics and lung fluid balance. Comprehensive Physiology\| PubMed ID: 23728978	2012
Reactive oxygen species in inflammation and tissue injury. Antioxidants & redox signaling\| PubMed ID: 23991888	2014
A critical role for Lyn kinase in strengthening endothelial integrity and barrier function. Blood\| PubMed ID: 24108461	2013
Caveolin-1 Tyr14 phosphorylation induces interaction with TLR4 in endothelial cells and mediates MyD88-dependent signaling and sepsis-induced lung inflammation. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 24244013	2013
Cooperative interaction of trp melastatin channel transient receptor potential (TRPM2) with its splice variant TRPM2 short variant is essential for endothelial cell apoptosis. Circulation research\| PubMed ID: 24337049	2014
Flk1+ and VE-cadherin+ endothelial cells derived from iPSCs recapitulates vascular development during differentiation and display similar angiogenic potential as ESC-derived cells. PloS one\| PubMed ID: 24386480	2013
The transcription factor DREAM represses the deubiquitinase A20 and mediates inflammation. Nature immunology\| PubMed ID: 24487321	2014
Genetic variation is the major determinant of individual differences in leukocyte endothelial adhesion. PloS one\| PubMed ID: 24520339	2014
Prevention of vascular inflammation by nanoparticle targeting of adherent neutrophils. Nature nanotechnology\| PubMed ID: 24561355	2014
Therapeutic administration of the chemokine CXCL1/KC abrogates autoimmune inflammatory heart disease. PloS one\| PubMed ID: 24586934	2014
Evidence of a common mechanism of disassembly of adherens junctions through Gα13 targeting of VE-cadherin. The Journal of experimental medicine\| PubMed ID: 24590762	2014
Endothelial progenitor cells and vascular repair. Current opinion in hematology\| PubMed ID: 24637956	2014
Regulating the regulator of ROS production. Cell research\| PubMed ID: 24839902	2014
Combinatorial therapy with acetylation and methylation modifiers attenuates lung vascular hyperpermeability in endotoxemia-induced mouse inflammatory lung injury. The American journal of pathology\| PubMed ID: 24929240	2014
Differential role for p120-catenin in regulation of TLR4 signaling in macrophages. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 25015829	2014
Cooperative signaling via transcription factors NF-κB and AP1/c-Fos mediates endothelial cell STIM1 expression and hyperpermeability in response to endotoxin. The Journal of biological chemistry\| PubMed ID: 25016017	2014
KIF13B regulates angiogenesis through Golgi to plasma membrane trafficking of VEGFR2. Journal of cell science\| PubMed ID: 25128562	2014
Reprogramming fibroblasts to endothelial cells: converted or born again? Circulation\| PubMed ID: 25186942	2014
Microfluidic platform generates oxygen landscapes for localized hypoxic activation. Lab on a chip\| PubMed ID: 25315003	2014