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Tracking the Mammary Architectural Features and Detecting Breast Cancer with Magnetic Resonance Diffusion Tensor Imaging

Breast cancer is the most common cause of cancer among women worldwide. Early detection of breast cancer has a critical role in improving the quality of ...

Weizmann Institute of Science

This study summarizes our clinical and surgical experience with pediatric brain tumors that were initially presented with seizures. The records of 367 consecutive children, treated for brain tumors between the years 1996 and 2007, were retrospectively analyzed, focusing on the clinical manifestations, diagnostic gap, and postoperative seizure follow-up that lasted at least 2 years. Seizures, mainly focal, were the clinical manifestation of brain tumor in 57 of 367 children. Normal neurologic examination and electroencephalography (EEG) were in 77.8% and 37.5%, respectively. Diagnostic gap correlated with low-grade and temporal lobe tumors. Postoperative follow-up revealed freedom of seizure in 77.6%. Favorable seizure outcome correlated with low preoperative seizures frequency, preoperative response to antiepileptic drugs, and hemispheric tumor location. We conclude that response to antiepileptic drugs, generalized seizures, normal EEG, and normal neurologic examination should not exclude tumor etiology. Moreover, broader indications for imaging should be employed while evaluating a child with a seizure.

Seizures as the clinical presenting symptom in children with brain tumors.

Clinical results of DTI.

Advantages and drawbacks of breast DTI.

To investigate the parameters obtained with magnetic resonance (MR) diffusion-tensor imaging (DTI) of the breast throughout the menstrual cycle phases, during lactation, and after menopause, with and without hormone replacement therapy (HRT).

Diffusion-tensor MR imaging of the breast: hormonal regulation.

Evaluating the usefulness of diffusion-weighted spatio-temporal encoding (SPEN) methods to provide quantitative apparent diffusion coefficient (ADC)-based characterizations of healthy and malignant human breast tissues, in comparison with results obtained using techniques based on spin-echo echo planar imaging (SE-EPI).

Article	Year
Seizures as the clinical presenting symptom in children with brain tumors. Journal of child neurology\| PubMed ID: 22628219	2013
Clinical results of DTI. European journal of radiology\| PubMed ID: 23083570	2012
Advantages and drawbacks of breast DTI. European journal of radiology\| PubMed ID: 23083598	2012
Diffusion-tensor MR imaging of the breast: hormonal regulation. Radiology\| PubMed ID: 24533873	2014
Overcoming limitations in diffusion-weighted MRI of breast by spatio-temporal encoding. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine\| PubMed ID: 25045867	2014

Noam Nissan

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