Richard Fedorak

Department of Medicine, University of Alberta

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 9	2014

Other Publications

Article	Year
CAG interactive lecture series: a Web-based learning program. Canadian journal of gastroenterology = Journal canadien de gastroenterologie\| PubMed ID: 11826342	2002
Clinical experience with infliximab for Crohn's disease: the first 100 patients in Edmonton, Alberta. Canadian journal of gastroenterology = Journal canadien de gastroenterologie\| PubMed ID: 11930194	2002
A model for partnership and research between the CAG and sponsors. Canadian journal of gastroenterology = Journal canadien de gastroenterologie\| PubMed ID: 12045785	2002
Normal Breast Milk Limits the Development of Colitis in IL-10-Deficient Mice. Inflammatory bowel diseases\| PubMed ID: 12454614	2002
Potato glycoalkaloids adversely affect intestinal permeability and aggravate inflammatory bowel disease. Inflammatory bowel diseases\| PubMed ID: 12479649	2002
Lack of interleukin-10 leads to intestinal inflammation, independent of the time at which luminal microbial colonization occurs. Inflammatory bowel diseases\| PubMed ID: 12769442	2003
The frequency of vitamin D deficiency in adults with Crohn's disease. Canadian journal of gastroenterology = Journal canadien de gastroenterologie\| PubMed ID: 12945007	2003
Absence of symptomatic benefit of lansoprazole, clarithromycin, and amoxicillin triple therapy in eradication of Helicobacter pylori positive, functional (nonulcer) dyspepsia. The American journal of gastroenterology\| PubMed ID: 14499772	2003
The 1993 Canadian Association of Gastroenterology Strategic Plan: excellence in achievement. Canadian journal of gastroenterology = Journal canadien de gastroenterologie\| PubMed ID: 14631464	2003
Infliximab maintenance therapy for fistulizing Crohn's disease. The New England journal of medicine\| PubMed ID: 14985485	2004
Endoscopic perforation rates at a Canadian university teaching hospital. Canadian journal of gastroenterology = Journal canadien de gastroenterologie\| PubMed ID: 15054498	2004
The Canadian Registry on Nonvariceal Upper Gastrointestinal Bleeding and Endoscopy (RUGBE): Endoscopic hemostasis and proton pump inhibition are associated with improved outcomes in a real-l... The American journal of gastroenterology\| PubMed ID: 15233660	2004
Bones and Crohn's: risk factors associated with low bone mineral density in patients with Crohn's disease. Inflammatory bowel diseases\| PubMed ID: 15290915	2004
Probiotics and the management of inflammatory bowel disease. Inflammatory bowel diseases\| PubMed ID: 15290926	2004
Canadian Association of Gastroenterology Clinical Practice Guidelines: the use of infliximab in Crohn's disease. Canadian journal of gastroenterology = Journal canadien de gastroenterologie\| PubMed ID: 15372114	2004
Targeted delivery, safety, and efficacy of oral enteric-coated formulations of budesonide. Advanced drug delivery reviews\| PubMed ID: 15555744	2005
Is it time to re-classify Crohn's disease? Best practice & research. Clinical gastroenterology\| PubMed ID: 15588801	2004
Probiotics and prebiotics in gastrointestinal disorders. Current opinion in gastroenterology\| PubMed ID: 15703637	2004
Randomized trial of etidronate plus calcium and vitamin D for treatment of low bone mineral density in Crohn's disease. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association\| PubMed ID: 15704046	2005
Thiopurine methyltransferase enzyme activity determination before treatment of inflammatory bowel disease with azathioprine: effect on cost and adverse events. Canadian journal of gastroenterology = Journal canadien de gastroenterologie\| PubMed ID: 15776134	2005
Effects of formal education for patients with inflammatory bowel disease: a randomized controlled trial. Canadian journal of gastroenterology = Journal canadien de gastroenterologie\| PubMed ID: 15861266	2005
Association with selected bacteria does not cause enterocolitis in IL-10 gene-deficient mice despite a systemic immune response. Digestive diseases and sciences\| PubMed ID: 15906767	2005
Treatment of ulcerative colitis with a humanized antibody to the alpha4beta7 integrin. The New England journal of medicine\| PubMed ID: 15958805	2005
VSL#3 probiotic-mixture induces remission in patients with active ulcerative colitis. The American journal of gastroenterology\| PubMed ID: 15984978	2005
Postoperative Crohn's disease. Inflammatory bowel diseases\| PubMed ID: 16043993	2005
The role of enteric microflora in inflammatory bowel disease: human and animal studies with probiotics and prebiotics. Gastroenterology clinics of North America\| PubMed ID: 16084308	2005
A randomized, placebo-controlled trial of certolizumab pegol (CDP870) for treatment of Crohn's disease. Gastroenterology\| PubMed ID: 16143120	2005
Probiotics and nutraceuticals: non-medicinal treatments of gastrointestinal diseases. Current opinion in pharmacology\| PubMed ID: 16214413	2005
Probiotics in the management of inflammatory bowel disease. MedGenMed : Medscape general medicine\| PubMed ID: 16369245	2005
Human anti-tumor necrosis factor monoclonal antibody (adalimumab) in Crohn's disease: the CLASSIC-I trial. Gastroenterology\| PubMed ID: 16472588	2006
Probiotics in the treatment of inflammatory bowel disease. Journal of clinical gastroenterology\| PubMed ID: 16633133	2006
Recommendations for probiotic use. Journal of clinical gastroenterology\| PubMed ID: 16633136	2006
Bacterial antigens alone can influence intestinal barrier integrity, but live bacteria are required for initiation of intestinal inflammation and injury. Inflammatory bowel diseases\| PubMed ID: 16775486	2006
Onercept for moderate-to-severe Crohn's disease: a randomized, double-blind, placebo-controlled trial. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association\| PubMed ID: 16797249	2006
The bacteriology of biopsies differs between newly diagnosed, untreated, Crohn's disease and ulcerative colitis patients. Journal of medical microbiology\| PubMed ID: 16849736	2006
The epidemiology of inflammatory bowel disease in Canada: a population-based study. The American journal of gastroenterology\| PubMed ID: 16863561	2006
A defect in epithelial barrier integrity is not required for a systemic response to bacterial antigens or intestinal injury in T cell receptor-alpha gene-deficient mice. Inflammatory bowel diseases\| PubMed ID: 16917231	2006
The role of antibiotic and probiotic therapies in current and future management of inflammatory bowel disease. Current gastroenterology reports\| PubMed ID: 17105688	2006
Effects of probiotic therapy in critically ill patients: a randomized, double-blind, placebo-controlled trial. The American journal of clinical nutrition\| PubMed ID: 17344505	2007
Epithelial barrier disruption allows nondisease-causing bacteria to initiate and sustain IBD in the IL-10 gene-deficient mouse. Inflammatory bowel diseases\| PubMed ID: 17427241	2007
Vertebral fractures and role of low bone mineral density in Crohn's disease. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association\| PubMed ID: 17482522	2007
Natalizumab for the treatment of active Crohn's disease: results of the ENCORE Trial. Gastroenterology\| PubMed ID: 17484865	2007
American gastroenterological association consensus development conference on the use of biologics in the treatment of inflammatory bowel disease, June 21-23, 2006. Gastroenterology\| PubMed ID: 17631151	2007
Increased risk of colorectal cancer in ulcerative colitis patients diagnosed after 40 years of age. Canadian journal of gastroenterology = Journal canadien de gastroenterologie\| PubMed ID: 17637947	2007
CD4+CD25+ regulatory T cells have divergent effects on intestinal inflammation in IL-10 gene-deficient mice. Digestive diseases and sciences\| PubMed ID: 17990114	2008
The role of probiotics in management of irritable bowel syndrome. Current gastroenterology reports\| PubMed ID: 17991340	2007
Differential clustering of bowel biopsy-associated bacterial profiles of specimens collected in Mexico and Canada: what do these profiles represent? Journal of medical microbiology\| PubMed ID: 18065676	2008
Certolizumab pegol, a monthly subcutaneously administered Fc-free anti-TNFalpha, improves health-related quality of life in patients with moderate to severe Crohn's disease. International journal of colorectal disease\| PubMed ID: 18071721	2008
Perinuclear antineutrophil cytoplasmic autoantibodies and anti-Saccharomyces cerevisiae antibodies as serological markers are not specific in the identification of Crohn's disease and ulcera... Canadian journal of gastroenterology = Journal canadien de gastroenterologie\| PubMed ID: 18209778	2008
Allopurinol to prevent pancreatitis after endoscopic retrograde cholangiopancreatography: a randomized placebo-controlled trial. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association\| PubMed ID: 18304883	2008
Exercise and inflammatory bowel disease. Canadian journal of gastroenterology = Journal canadien de gastroenterologie\| PubMed ID: 18478136	2008
Recommendations for probiotic use--2008. Journal of clinical gastroenterology\| PubMed ID: 18542033	2008
Probiotics in the treatment of human inflammatory bowel diseases: update 2008. Journal of clinical gastroenterology\| PubMed ID: 18542034	2008
Urinary metabolic profiles of inflammatory bowel disease in interleukin-10 gene-deficient mice. Analytical chemistry\| PubMed ID: 18558774	2008
A randomized trial of Ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with moderate-to-severe Crohn's disease. Gastroenterology\| PubMed ID: 18706417	2008
Understanding why probiotic therapies can be effective in treating IBD. Journal of clinical gastroenterology\| PubMed ID: 18806699	2008
Are there differences in type, dosage, and method of administration for the systemic steroids in IBD treatment? Inflammatory bowel diseases\| PubMed ID: 18816775	2008
Treatment of active Crohn's disease with MLN0002, a humanized antibody to the alpha4beta7 integrin. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association\| PubMed ID: 18829392	2008
Bacterial overgrowth and inflammation of small intestine after carboxymethylcellulose ingestion in genetically susceptible mice. Inflammatory bowel diseases\| PubMed ID: 18844217	2009
Helicobacter pylori infection in Canada's arctic: searching for the solutions. Canadian journal of gastroenterology = Journal canadien de gastroenterologie\| PubMed ID: 19018336	2008
Early experience with unsedated ultrathin 4.9 mm transnasal gastroscopy: a pilot study. Canadian journal of gastroenterology = Journal canadien de gastroenterologie\| PubMed ID: 19018337	2008
Probiotic preparation VSL#3 induces remission in children with mild to moderate acute ulcerative colitis: a pilot study. Inflammatory bowel diseases\| PubMed ID: 19067432	2009
Gastric intramural hematoma: a case report and literature review. Canadian journal of gastroenterology = Journal canadien de gastroenterologie\| PubMed ID: 19172203	2009
Does smoking reduce infliximab's effectiveness against Crohn's disease? Canadian journal of gastroenterology = Journal canadien de gastroenterologie\| PubMed ID: 19214288	2009
Long-term response rates to infliximab therapy for Crohn's disease in an outpatient cohort. Canadian journal of gastroenterology = Journal canadien de gastroenterologie\| PubMed ID: 19440565	2009
Oral administration of curcumin emulsified in carboxymethyl cellulose has a potent anti-inflammatory effect in the IL-10 gene-deficient mouse model of IBD. Digestive diseases and sciences\| PubMed ID: 19513843	2010
Peptic ulcer bleeding outcomes adversely affected by end-stage renal disease. Gastrointestinal endoscopy\| PubMed ID: 19595311	2010
Endpoints for clinical trials evaluating disease modification and structural damage in adults with Crohn's disease. Inflammatory bowel diseases\| PubMed ID: 19653291	2009
Pneumococcal pneumonia: potential for diagnosis through a urinary metabolic profile. Journal of proteome research\| PubMed ID: 19817432	2009
Randomized, double-blind, placebo-controlled trial of the oral interleukin-12/23 inhibitor apilimod mesylate for treatment of active Crohn's disease. Inflammatory bowel diseases\| PubMed ID: 19918967	2010
Naturally occurring glycoalkaloids in potatoes aggravate intestinal inflammation in two mouse models of inflammatory bowel disease. Digestive diseases and sciences\| PubMed ID: 20198430	2010
Certolizumab pegol in patients with moderate to severe Crohn's disease and secondary failure to infliximab. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association\| PubMed ID: 20451663	2010
A randomized trial of topical anesthesia comparing lidocaine versus lidocaine plus xylometazoline for unsedated transnasal upper gastrointestinal endoscopy. Canadian journal of gastroenterology = Journal canadien de gastroenterologie\| PubMed ID: 20485707	2010
Canadian Digestive Health Foundation Public Impact Series: gastroesophageal reflux disease in Canada: incidence, prevalence, and direct and indirect economic impact. Canadian journal of gastroenterology = Journal canadien de gastroenterologie\| PubMed ID: 20652158	2010
Patients with IBD are exposed to high levels of ionizing radiation through CT scan diagnostic imaging: a five-year study. Journal of clinical gastroenterology\| PubMed ID: 20679907	2011
Neonatal exposure to fecal antigens reduces intestinal inflammation. Inflammatory bowel diseases\| PubMed ID: 20824814	2011
Metabolomics and detection of colorectal cancer in humans: a systematic review. Future oncology (London, England)\| PubMed ID: 20919825	2010
Tumor necrosis factor-α monoclonal antibodies in the treatment of inflammatory bowel disease: clinical practice pharmacology. Gastroenterology clinics of North America\| PubMed ID: 20951917	2010
Mind the gaps: confocal endomicroscopy showed increased density of small bowel epithelial gaps in inflammatory bowel disease. Journal of clinical gastroenterology\| PubMed ID: 21030873	2011
Canadian Digestive Health Foundation Public Impact Series. Inflammatory bowel disease in Canada: Incidence, prevalence, and direct and indirect economic impact. Canadian journal of gastroenterology = Journal canadien de gastroenterologie\| PubMed ID: 21157579	2010
Adalimumab for induction of clinical remission in moderately to severely active ulcerative colitis: results of a randomised controlled trial. Gut\| PubMed ID: 21209123	2011
Inadequate knowledge of immunization guidelines: a missed opportunity for preventing infection in immunocompromised IBD patients. Inflammatory bowel diseases\| PubMed ID: 21337671	2012
Increased epithelial gaps in the small intestines of patients with inflammatory bowel disease: density matters. Gastrointestinal endoscopy\| PubMed ID: 21396639	2011
Probiotics in the management of ulcerative colitis. Gastroenterology & hepatology\| PubMed ID: 21437015	2010
Prevalence and Outcome of Upper Gastrointestinal Bleeding Post-coronary Artery Bypass Graft. International journal of health sciences\| PubMed ID: 21475474	2008
Predicting, treating and preventing postoperative recurrence of Crohn's disease: the state of the field. Canadian journal of gastroenterology = Journal canadien de gastroenterologie\| PubMed ID: 21499578	2011
Drug-disease interaction: Crohn's disease elevates verapamil plasma concentrations but reduces response to the drug proportional to disease activity. British journal of clinical pharmacology\| PubMed ID: 21592185	2011
Oropharyngeal Crohn's disease. Clinical and experimental gastroenterology\| PubMed ID: 21677821	2008
Intravenous injection of endogenous microbial components abrogates DSS-induced colitis. Digestive diseases and sciences\| PubMed ID: 21881971	2012
Health care resource use and costs in Crohn's disease before and after infliximab therapy. Canadian journal of gastroenterology = Journal canadien de gastroenterologie\| PubMed ID: 21912761	2011
Probiotic Therapies for IBD. Gastroenterology & hepatology\| PubMed ID: 21960828	2007
A randomized controlled trial of four precolonoscopy bowel cleansing regimens. Canadian journal of gastroenterology = Journal canadien de gastroenterologie\| PubMed ID: 22175055	2011
Validation of a point-of-care desk top device to quantitate fecal calprotectin and distinguish inflammatory bowel disease from irritable bowel syndrome. Journal of Crohn's & colitis\| PubMed ID: 22325175	2012
Risedronate improves bone mineral density in Crohn's disease: a two year randomized controlled clinical trial. Journal of Crohn's & colitis\| PubMed ID: 22398088	2012
Iron replacement therapy in inflammatory bowel disease patients with iron deficiency anemia: a systematic review and meta-analysis. Journal of Crohn's & colitis\| PubMed ID: 22405161	2012
Small bowel fibrosis and systemic inflammatory response after ileocolonic anastomosis in IL-10 null mice. The Journal of surgical research\| PubMed ID: 22482772	2012
Canadian Digestive Health Foundation Public Impact Series 3: irritable bowel syndrome in Canada. Incidence, prevalence, and direct and indirect economic impact. Canadian journal of gastroenterology = Journal canadien de gastroenterologie\| PubMed ID: 22590697	2012
Urinary NMR metabolomic profiles discriminate inflammatory bowel disease from healthy. Journal of Crohn's & colitis\| PubMed ID: 22626506	2013
Patients with inflammatory bowel disease exhibit dysregulated responses to microbial DNA. PloS one\| PubMed ID: 22649567	2012
World Gastroenterology Organisation Global Guidelines: probiotics and prebiotics October 2011. Journal of clinical gastroenterology\| PubMed ID: 22688142	2012
The sensitivity and specificity of guaiac and immunochemical fecal occult blood tests for the detection of advanced colonic adenomas and cancer. International journal of colorectal disease\| PubMed ID: 22696204	2012
A randomised phase I study of etrolizumab (rhuMAb β7) in moderate to severe ulcerative colitis. Gut\| PubMed ID: 22717454	2013
Canadian Digestive Health Foundation Public Impact Series 4: celiac disease in Canada. Incidence, prevalence, and direct and indirect economic impact. Canadian journal of gastroenterology = Journal canadien de gastroenterologie\| PubMed ID: 22720277	2012
Patients undergoing colorectal cancer screening underestimate their cancer risk and delay presentation for screening. Canadian journal of gastroenterology = Journal canadien de gastroenterologie\| PubMed ID: 22803015	2012
Canadian Digestive Health Foundation Public Impact Series 5: Pancreatitis in Canada. Incidence, prevalence, and direct and indirect economic impact. Canadian journal of gastroenterology = Journal canadien de gastroenterologie\| PubMed ID: 22891180	2012
Challenges to the design, execution, and analysis of randomized controlled trials for inflammatory bowel disease. Gastroenterology\| PubMed ID: 23000597	2012
Crohn's disease genotypes of patients in remission vs relapses after infliximab discontinuation. World journal of gastroenterology : WJG\| PubMed ID: 23049214	2012
Development and validation of an administrative case definition for inflammatory bowel diseases. Canadian journal of gastroenterology = Journal canadien de gastroenterologie\| PubMed ID: 23061064	2012
Probiotic bacteria in the prevention and the treatment of inflammatory bowel disease. Gastroenterology clinics of North America\| PubMed ID: 23101689	2012
Epithelial gaps in a rodent model of inflammatory bowel disease: a quantitative validation study. Clinical and translational gastroenterology\| PubMed ID: 23237881	2011
Increased epithelial gaps in the small intestine are predictive of hospitalization and surgery in patients with inflammatory bowel disease. Clinical and translational gastroenterology\| PubMed ID: 23238291	2012
Breaks in the wall: increased gaps in the intestinal epithelium of irritable bowel syndrome patients identified by confocal laser endomicroscopy (with videos). Gastrointestinal endoscopy\| PubMed ID: 23357497	2013
Celiac disease in children with inflammatory bowel disease: a prospective cohort study. The American journal of gastroenterology\| PubMed ID: 23459057	2013
Epithelial cell extrusion leads to breaches in the intestinal epithelium. Inflammatory bowel diseases\| PubMed ID: 23511029	2013
Environment and the inflammatory bowel diseases. Canadian journal of gastroenterology = Journal canadien de gastroenterologie\| PubMed ID: 23516681	2013
Adalimumab for orbital myositis in a patient with Crohn's disease who discontinued infliximab: a case report and review of the literature. BMC gastroenterology\| PubMed ID: 23556424	2013
Varicella zoster meningitis complicating combined anti-tumor necrosis factor and corticosteroid therapy in Crohn's disease. World journal of gastroenterology : WJG\| PubMed ID: 23745038	2013
Prospective Study of the Quality of Colonoscopies Performed by Primary Care Physicians: The Alberta Primary Care Endoscopy (APC-Endo) Study. PloS one\| PubMed ID: 23826186	2013
Metabolomic profiles are gender, disease and time specific in the interleukin-10 gene-deficient mouse model of inflammatory bowel disease. PloS one\| PubMed ID: 23874435	2013
Vedolizumab as induction and maintenance therapy for Crohn's disease. The New England journal of medicine\| PubMed ID: 23964933	2013
Phenotypic features of Crohn's disease associated with failure of medical treatment. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association\| PubMed ID: 23978351	2014
Overview of subsequent entry biologics for the management of inflammatory bowel disease and Canadian Association of Gastroenterology position statement on subsequent entry biologics. Canadian journal of gastroenterology = Journal canadien de gastroenterologie\| PubMed ID: 24106727	2013
Methotrexate in combination with infliximab is no more effective than infliximab alone in patients with Crohn's disease. Gastroenterology\| PubMed ID: 24269926	2014
A machine-learned predictor of colonic polyps based on urinary metabolomics. BioMed research international\| PubMed ID: 24307992	2013
Disease manifestations of Helicobacter pylori infection in Arctic Canada: using epidemiology to address community concerns. BMJ open\| PubMed ID: 24401722	2014
Adalimumab versus infliximab for the treatment of moderate to severe ulcerative colitis in adult patients naïve to anti-TNF therapy: an indirect treatment comparison meta-analysis. Journal of Crohn's & colitis\| PubMed ID: 24491514	2014
Distance management of inflammatory bowel disease: systematic review and meta-analysis. World journal of gastroenterology : WJG\| PubMed ID: 24574756	2014
Development and validation of a highly sensitive urine-based test to identify patients with colonic adenomatous polyps. Clinical and translational gastroenterology\| PubMed ID: 24646506	2014
Real-life Treatment Paradigms Show Infliximab Is Cost-effective for Management of Ulcerative Colitis. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association\| PubMed ID: 24674943	2014
Vitamin D improves inflammatory bowel disease outcomes: basic science and clinical review. World journal of gastroenterology : WJG\| PubMed ID: 24803805	2014
Crohn's disease outpatients treated with adalimumab have an earlier secondary loss of response and requirement for dose escalation compared to infliximab: A real life cohort study. Journal of Crohn's & colitis\| PubMed ID: 24947334	2014
HLA-DQA1-HLA-DRB1 variants confer susceptibility to pancreatitis induced by thiopurine immunosuppressants. Nature genetics\| PubMed ID: 25217962	2014
Response to letter to the editor. Canadian journal of gastroenterology & hepatology\| PubMed ID: 25229468	2014