Caroline A. Owen

Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital - Harvard Medical School

Affiliated withBrigham and Women's Hospital - Harvard Medical School Lovelace Respiratory Research Institute

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 38	2015

Other Publications

Article	Year
The club cell and its protein, CC16: time to shine. The Lancet. Respiratory medicine\| PubMed ID: 24461745	2013
ADAM-33 surfaces as an asthma gene. The New England journal of medicine\| PubMed ID: 12239266	2002
Inducible expression of tissue inhibitor of metalloproteinases-resistant matrix metalloproteinase-9 on the cell surface of neutrophils. American journal of respiratory cell and molecular biology\| PubMed ID: 12663332	2003
Neutrophil elastase in human atherosclerotic plaques: production by macrophages. Circulation\| PubMed ID: 12771009	2003
Membrane-bound matrix metalloproteinase-8 on activated polymorphonuclear cells is a potent, tissue inhibitor of metalloproteinase-resistant collagenase and serpinase. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 15187163	2004
Proteinases and oxidants as targets in the treatment of chronic obstructive pulmonary disease. Proceedings of the American Thoracic Society\| PubMed ID: 16267366	2005
Induction of the plasminogen activator system by mechanical stimulation of human bronchial epithelial cells. American journal of respiratory cell and molecular biology\| PubMed ID: 16794260	2006
The sulfate groups of chondroitin sulfate- and heparan sulfate-containing proteoglycans in neutrophil plasma membranes are novel binding sites for human leukocyte elastase and cathepsin G. The Journal of biological chemistry\| PubMed ID: 17384412	2007
CD8+ T Cells are required for inflammation and destruction in cigarette smoke-induced emphysema in mice. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 17548647	2007
Leukocyte cell surface proteinases: regulation of expression, functions, and mechanisms of surface localization. The international journal of biochemistry & cell biology\| PubMed ID: 18329945	2008
Roles for proteinases in the pathogenesis of chronic obstructive pulmonary disease. International journal of chronic obstructive pulmonary disease\| PubMed ID: 18686734	2008
ADAM8: a new therapeutic target for asthma. Expert opinion on therapeutic targets\| PubMed ID: 19397475	2009
Matrix metalloproteinase-8 inactivates macrophage inflammatory protein-1 alpha to reduce acute lung inflammation and injury in mice. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 20042585	2010
Matrix metalloproteinases: all the RAGE in the acute respiratory distress syndrome. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 21296893	2011
Polymorphonuclear neutrophils move into the fast lane in chronic obstructive pulmonary disease. American journal of respiratory and critical care medicine\| PubMed ID: 21531949	2011
Genetically Manipulated Mouse Models of Lung Disease: Potential and Pitfalls. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 22198907	2011
Interleukin-18: the master regulator driving destructive and remodeling processes in the lungs of patients with chronic obstructive pulmonary disease? American journal of respiratory and critical care medicine\| PubMed ID: 22661518	2012
Inflammation in COPD: implications for management. The American journal of medicine\| PubMed ID: 23164484	2012
Selenoprotein N deficiency in mice is associated with abnormal lung development. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 23325319	2013
The role of systemic inflammatory biomarkers to predict mortality in chronic obstructive pulmonary disease. Expert review of respiratory medicine\| PubMed ID: 23362815	2013
Profibrotic activities for matrix metalloproteinase-8 during bleomycin-mediated lung injury. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 23487425	2013
Adipose-derived stem cells weigh in as novel therapeutics for acute lung injury. Stem cell research & therapy\| PubMed ID: 23510703	2013
Adam8 limits the development of allergic airway inflammation in mice. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 23670189	2013
Rapid lung function decline in smokers is a risk factor for COPD and is attenuated by angiotensin-converting enzyme inhibitor use. Chest\| PubMed ID: 24008986	2014
Histone deacetylase 6-mediated selective autophagy regulates COPD-associated cilia dysfunction. The Journal of clinical investigation\| PubMed ID: 24200693	2013
Comparison of arterial and venous blood biomarker levels in chronic obstructive pulmonary disease. F1000Research\| PubMed ID: 24555057	2013
Functional characterization of polymorphisms in the peptidase inhibitor 3 (elafin) gene and validation of their contribution to risk of acute respiratory distress syndrome. American journal of respiratory cell and molecular biology\| PubMed ID: 24617927	2014
Mononuclear phagocytes and airway epithelial cells: novel sources of matrix metalloproteinase-8 (MMP-8) in patients with idiopathic pulmonary fibrosis. PloS one\| PubMed ID: 24828408	2014
Idiopathic pulmonary fibrosis and coronary artery disease. Multidisciplinary respiratory medicine\| PubMed ID: 24976970	2014
Effects of sex hormones on bronchial reactivity during the menstrual cycle. BMC pulmonary medicine\| PubMed ID: 24984749	2014
ADAM9 is a novel product of polymorphonuclear neutrophils: regulation of expression and contributions to extracellular matrix protein degradation during acute lung injury. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 25063875	2014
Mitophagy-dependent necroptosis contributes to the pathogenesis of COPD. The Journal of clinical investigation\| PubMed ID: 25083992	2014
Folliculin regulates cell-cell adhesion, AMPK, and mTORC1 in a cell-type-specific manner in lung-derived cells. Physiological reports\| PubMed ID: 25121506	2014
A Novel Nonhuman Primate Model of Cigarette Smoke-Induced Airway Disease. The American journal of pathology\| PubMed ID: 25542772	2014