Maria E. Figueroa

Department of Pathology, University of Michigan

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 115	2015

Other Publications

Article	Year
Two-step upflow anaerobic sludge bed system for sewage treatment under subtropical conditions with posttreatment in waste stabilization ponds. Applied biochemistry and biotechnology\| PubMed ID: 12794292	2003
Comparative isoschizomer profiling of cytosine methylation: the HELP assay. Genome research\| PubMed ID: 16809668	2006
Smad1 and Smad5 differentially regulate embryonic hematopoiesis. Blood\| PubMed ID: 17761518	2007
CG dinucleotide clustering is a species-specific property of the genome. Nucleic acids research\| PubMed ID: 17932072	2007
An integrative genomic and epigenomic approach for the study of transcriptional regulation. PloS one\| PubMed ID: 18365023	2008
Kaiso contributes to DNA methylation-dependent silencing of tumor suppressor genes in colon cancer cell lines. Cancer research\| PubMed ID: 18794111	2008
Genome-wide epigenetic analysis delineates a biologically distinct immature acute leukemia with myeloid/T-lymphoid features. Blood\| PubMed ID: 19168792	2009
Genome-wide determination of DNA methylation by Hpa II tiny fragment enrichment by ligation-mediated PCR (HELP) for the study of acute leukemias. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 19277580	2009
High-resolution genome-wide cytosine methylation profiling with simultaneous copy number analysis and optimization for limited cell numbers. Nucleic acids research\| PubMed ID: 19386619	2009
MDS and secondary AML display unique patterns and abundance of aberrant DNA methylation. Blood\| PubMed ID: 19652201	2009
DNA methylation signatures identify biologically distinct subtypes in acute myeloid leukemia. Cancer cell\| PubMed ID: 20060365	2010
Promoter hypermethylation in MLL-r infant acute lymphoblastic leukemia: biology and therapeutic targeting. Blood\| PubMed ID: 20215641	2010
HELP (HpaII tiny fragment enrichment by ligation-mediated PCR) assay for DNA methylation profiling of primary normal and malignant B lymphocytes. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 20217579	2010
DNMT3B7, a truncated DNMT3B isoform expressed in human tumors, disrupts embryonic development and accelerates lymphomagenesis. Cancer research\| PubMed ID: 20587527	2010
Aberrant DNA hypermethylation signature in acute myeloid leukemia directed by EVI1. Blood\| PubMed ID: 20855866	2011
BCL6 repression of EP300 in human diffuse large B cell lymphoma cells provides a basis for rational combinatorial therapy. The Journal of clinical investigation\| PubMed ID: 21041953	2010
Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation. Cancer cell\| PubMed ID: 21130701	2010
Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation. Cancer cell\| PubMed ID: 21723200	2011
DNA methyltransferase 1 and DNA methylation patterning contribute to germinal center B-cell differentiation. Blood\| PubMed ID: 21828137	2011
IDH mutation impairs histone demethylation and results in a block to cell differentiation. Nature\| PubMed ID: 22343901	2012
Prognostic relevance of integrated genetic profiling in acute myeloid leukemia. The New England journal of medicine\| PubMed ID: 22417203	2012
Mutant DNMT3A: a marker of poor prognosis in acute myeloid leukemia. Blood\| PubMed ID: 22490330	2012
Base-pair resolution DNA methylation sequencing reveals profoundly divergent epigenetic landscapes in acute myeloid leukemia. PLoS genetics\| PubMed ID: 22737091	2012
IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics. Nature\| PubMed ID: 22763442	2012
CD25 expression status improves prognostic risk classification in AML independent of established biomarkers: ECOG phase 3 trial, E1900. Blood\| PubMed ID: 22855599	2012
H2.0-like homeobox regulates early hematopoiesis and promotes acute myeloid leukemia. Cancer cell\| PubMed ID: 22897850	2012
Recurrent somatic TET2 mutations in normal elderly individuals with clonal hematopoiesis. Nature genetics\| PubMed ID: 23001125	2012
methylKit: a comprehensive R package for the analysis of genome-wide DNA methylation profiles. Genome biology\| PubMed ID: 23034086	2012
C/EBPγ deregulation results in differentiation arrest in acute myeloid leukemia. The Journal of clinical investigation\| PubMed ID: 23160200	2012
Interpreting new molecular genetics in myelodysplastic syndromes. Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program\| PubMed ID: 23233561	2012
Notch activation inhibits AML growth and survival: a potential therapeutic approach. The Journal of experimental medicine\| PubMed ID: 23359069	2013
Satb1 regulates the self-renewal of hematopoietic stem cells by promoting quiescence and repressing differentiation commitment. Nature immunology\| PubMed ID: 23563689	2013
Understanding and utilizing new molecular genetics in MDS. Clinical advances in hematology & oncology : H&O\| PubMed ID: 23598913	2013
Integrated genetic and epigenetic analysis of childhood acute lymphoblastic leukemia. The Journal of clinical investigation\| PubMed ID: 23921123	2013
Development of acute megakaryoblastic leukemia in Down syndrome is associated with sequential epigenetic changes. Blood\| PubMed ID: 23980066	2013
Epigenetic roles of MLL oncoproteins are dependent on NF-κB. Cancer cell\| PubMed ID: 24054986	2013
PRMT4 blocks myeloid differentiation by assembling a methyl-RUNX1-dependent repressor complex. Cell reports\| PubMed ID: 24332853	2013
Microsphere-based multiplex analysis of DNA methylation in acute myeloid leukemia. The Journal of molecular diagnostics : JMD\| PubMed ID: 24373919	2014
Prolonged administration of azacitidine with or without entinostat for myelodysplastic syndrome and acute myeloid leukemia with myelodysplasia-related changes: results of the US Leukemia Int... Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 24663049	2014
Two splice-factor mutant leukemia subgroups uncovered at the boundaries of MDS and AML using combined gene expression and DNA-methylation profiling. Blood\| PubMed ID: 24668493	2014
Epigenetic deregulation in myeloid malignancies. Translational research : the journal of laboratory and clinical medicine\| PubMed ID: 24813528	2015
MethylSig: a whole genome DNA methylation analysis pipeline. Bioinformatics (Oxford, England)\| PubMed ID: 24836530	2014
Validation of DNA methylation to predict outcome in acute myeloid leukemia by use of xMELP. Clinical chemistry\| PubMed ID: 25348669	2015
DNA hydroxymethylation profiling reveals that WT1 mutations result in loss of TET2 function in acute myeloid leukemia. Cell reports\| PubMed ID: 25482556	2014
Plasticity of DNA methylation in a nerve injury model of pain. Epigenetics : official journal of the DNA Methylation Society\| PubMed ID: 25621511	2015
Musashi2 sustains the mixed-lineage leukemia-driven stem cell regulatory program. The Journal of clinical investigation\| PubMed ID: 25664853	2015