Didier Y.R. Stainier

Department for Biochemistry and Biophysics, University of California San Francisco

Affiliated withUniversity of California San Francisco Max-Planck Institute for Heart and Lung Research

Research Area

Biography

Didier Y.R. Stainier has not added Biography.
If you are Didier Y.R. Stainier and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 16	2014

Other Publications

Article	Year
The elongation factors Pandora/Spt6 and Foggy/Spt5 promote transcription in the zebrafish embryo. Development (Cambridge, England)\| PubMed ID: 11923199	2002
A glimpse into the molecular entrails of endoderm formation. Genes & development\| PubMed ID: 11959838	2002
Cardiac troponin T is essential in sarcomere assembly and cardiac contractility. Nature genetics\| PubMed ID: 11967535	2002
A window to the heart: can zebrafish mutants help us understand heart disease in humans? Trends in genetics : TIG\| PubMed ID: 12350332	2002
The guts of endoderm formation. Results and problems in cell differentiation\| PubMed ID: 12353482	2002
Pattern formation: swimming in retinoic acid. Current biology : CB\| PubMed ID: 12401191	2002
Lipid receptors in cardiovascular development. Annual review of physiology\| PubMed ID: 12471161	2003
Development. Fishing out a new heart. Science (New York, N.Y.)\| PubMed ID: 12481123	2002
From endoderm formation to liver and pancreas development in zebrafish. Mechanisms of development\| PubMed ID: 12490292	2003
Two endothelin 1 effectors, hand2 and bapx1, pattern ventral pharyngeal cartilage and the jaw joint. Development (Cambridge, England)\| PubMed ID: 12588851	2003
Formation of the digestive system in zebrafish. I. Liver morphogenesis. Developmental biology\| PubMed ID: 12645931	2003
In vivo regulation of the chicken cardiac troponin T gene promoter in zebrafish embryos. Developmental dynamics : an official publication of the American Association of Anatomists\| PubMed ID: 12889057	2003
Entrails, heart, brain, limbs, and lymphatics- a recipe for success? Developmental cell\| PubMed ID: 12919671	2003
The Mix family homeodomain gene bonnie and clyde functions with other components of the Nodal signaling pathway to regulate neural patterning in zebrafish. Development (Cambridge, England)\| PubMed ID: 12930774	2003
Formation of the digestive system in zebrafish. II. Pancreas morphogenesis. Developmental biology\| PubMed ID: 12941629	2003
Developmental biology: twisting the body into shape. Nature\| PubMed ID: 14523426	2003
Mutation of weak atrium/atrial myosin heavy chain disrupts atrial function and influences ventricular morphogenesis in zebrafish. Development (Cambridge, England)\| PubMed ID: 14573521	2003
A cellular framework for gut-looping morphogenesis in zebrafish. Science (New York, N.Y.)\| PubMed ID: 14576439	2003
Vegfc is required for vascular development and endoderm morphogenesis in zebrafish. EMBO reports\| PubMed ID: 14710191	2004
Fibronectin regulates epithelial organization during myocardial migration in zebrafish. Developmental cell\| PubMed ID: 15030760	2004
Notch signaling can regulate endoderm formation in zebrafish. Developmental dynamics : an official publication of the American Association of Anatomists\| PubMed ID: 15042699	2004
The endothelial-cell-derived secreted factor Egfl7 regulates vascular tube formation. Nature\| PubMed ID: 15085134	2004
Early myocardial function affects endocardial cushion development in zebrafish. PLoS biology\| PubMed ID: 15138499	2004
Cardiac development. Methods in cell biology\| PubMed ID: 15602887	2004
Hand2 regulates epithelial formation during myocardial diferentiation. Current biology : CB\| PubMed ID: 15786591	2005
No organ left behind: tales of gut development and evolution. Science (New York, N.Y.)\| PubMed ID: 15790841	2005
Microarray analysis of zebrafish cloche mutant using amplified cDNA and identification of potential downstream target genes. Developmental dynamics : an official publication of the American Association of Anatomists\| PubMed ID: 15937927	2005
nanor, a novel zygotic gene, is expressed initially at the midblastula transition in zebrafish. Biochemical and biophysical research communications\| PubMed ID: 15961062	2005
Genetic and cellular analyses of zebrafish atrioventricular cushion and valve development. Development (Cambridge, England)\| PubMed ID: 16107477	2005
Formation of the digestive system in zebrafish: III. Intestinal epithelium morphogenesis. Developmental biology\| PubMed ID: 16125164	2005
Vertebrate Smoothened functions at the primary cilium. Nature\| PubMed ID: 16136078	2005
Cellular and molecular analyses of vascular tube and lumen formation in zebrafish. Development (Cambridge, England)\| PubMed ID: 16251212	2005
In vivo cell biology: following the zebrafish trend. Trends in cell biology\| PubMed ID: 16406520	2006
Mesodermal Wnt2b signalling positively regulates liver specification. Nature\| PubMed ID: 16799568	2006
A common progenitor for haematopoietic and endothelial lineages in the zebrafish gastrula. Nature\| PubMed ID: 16988712	2006
The yolk syncytial layer regulates myocardial migration by influencing extracellular matrix assembly in zebrafish. Development (Cambridge, England)\| PubMed ID: 17008449	2006
The HeArt of regeneration. Cell\| PubMed ID: 17081969	2006
Microsomal triglyceride transfer protein is required for yolk lipid utilization and absorption of dietary lipids in zebrafish larvae. Biochemistry\| PubMed ID: 17176039	2006
Fgf10 regulates hepatopancreatic ductal system patterning and differentiation. Nature genetics\| PubMed ID: 17259985	2007
A mutation in zebrafish hmgcr1b reveals a role for isoprenoids in vertebrate heart-tube formation. Current biology : CB\| PubMed ID: 17276918	2007
Conditional targeted cell ablation in zebrafish: a new tool for regeneration studies. Developmental dynamics : an official publication of the American Association of Anatomists\| PubMed ID: 17326133	2007
The g protein-coupled receptor agtrl1b regulates early development of myocardial progenitors. Developmental cell\| PubMed ID: 17336906	2007
Bmp and Fgf signaling are essential for liver specification in zebrafish. Development (Cambridge, England)\| PubMed ID: 17507405	2007
A transgene-assisted genetic screen identifies essential regulators of vascular development in vertebrate embryos. Developmental biology\| PubMed ID: 17531218	2007
Zebrafish model for human long QT syndrome. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17592134	2007
Genetic control of single lumen formation in the zebrafish gut. Nature cell biology\| PubMed ID: 17632505	2007
Even fluorescence excitation by multidirectional selective plane illumination microscopy (mSPIM). Optics letters\| PubMed ID: 17767321	2007
Birc2 (cIap1) regulates endothelial cell integrity and blood vessel homeostasis. Nature genetics\| PubMed ID: 17934460	2007
Lessons from "lower" organisms: what worms, flies, and zebrafish can teach us about human energy metabolism. PLoS genetics\| PubMed ID: 18081423	2007
High-speed imaging of developing heart valves reveals interplay of morphogenesis and function. Development (Cambridge, England)\| PubMed ID: 18272595	2008
Foxn4 directly regulates tbx2b expression and atrioventricular canal formation. Genes & development\| PubMed ID: 18347092	2008
Multiple roles for Med12 in vertebrate endoderm development. Developmental biology\| PubMed ID: 18394596	2008
Intra-endodermal interactions are required for pancreatic beta cell induction. Developmental cell\| PubMed ID: 18410733	2008
Genetic and physiologic dissection of the vertebrate cardiac conduction system. PLoS biology\| PubMed ID: 18479184	2008
Graded levels of Ptf1a differentially regulate endocrine and exocrine fates in the developing pancreas. Genes & development\| PubMed ID: 18519637	2008
Nitroreductase-mediated cell/tissue ablation in zebrafish: a spatially and temporally controlled ablation method with applications in developmental and regeneration studies. Nature protocols\| PubMed ID: 18536643	2008
miR-126 regulates angiogenic signaling and vascular integrity. Developmental cell\| PubMed ID: 18694566	2008
Regulation of neurocoel morphogenesis by Pard6 gamma b. Developmental biology\| PubMed ID: 18817769	2008
Endothelial signals modulate hepatocyte apicobasal polarization in zebrafish. Current biology : CB\| PubMed ID: 18951027	2008
Bmp2 signaling regulates the hepatic versus pancreatic fate decision. Developmental cell\| PubMed ID: 19000838	2008
microRNA-138 modulates cardiac patterning during embryonic development. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19004786	2008
The spinster homolog, two of hearts, is required for sphingosine 1-phosphate signaling in zebrafish. Current biology : CB\| PubMed ID: 19062281	2008
Combinatorial regulation of endothelial gene expression by ets and forkhead transcription factors. Cell\| PubMed ID: 19070576	2008
Abnormal nuclear pore formation triggers apoptosis in the intestinal epithelium of elys-deficient zebrafish. Gastroenterology\| PubMed ID: 19073184	2009
Genetic evidence for a noncanonical function of seryl-tRNA synthetase in vascular development. Circulation research\| PubMed ID: 19423847	2009
Transcriptional silencing and reactivation in transgenic zebrafish. Genetics\| PubMed ID: 19433629	2009
The extracellular domain of Smoothened regulates ciliary localization and is required for high-level Hh signaling. Current biology : CB\| PubMed ID: 19464178	2009
Selective plane illumination microscopy techniques in developmental biology. Development (Cambridge, England)\| PubMed ID: 19465594	2009
Loss of Dnmt1 catalytic activity reveals multiple roles for DNA methylation during pancreas development and regeneration. Developmental biology\| PubMed ID: 19631206	2009
Distinct populations of quiescent and proliferative pancreatic beta-cells identified by HOTcre mediated labeling. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19706417	2009
Notch signaling functions as a cell-fate switch between the endothelial and hematopoietic lineages. Current biology : CB\| PubMed ID: 19747827	2009
Arterial-venous segregation by selective cell sprouting: an alternative mode of blood vessel formation. Science (New York, N.Y.)\| PubMed ID: 19815777	2009
Limited forward trafficking of connexin 43 reduces cell-cell coupling in stressed human and mouse myocardium. The Journal of clinical investigation\| PubMed ID: 20038810	2010
Suppression of Alk8-mediated Bmp signaling cell-autonomously induces pancreatic beta-cells in zebrafish. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 20080554	2010
Haematopoietic stem cells derive directly from aortic endothelium during development. Nature\| PubMed ID: 20154733	2010
Noncanonical activity of seryl-transfer RNA synthetase and vascular development. Trends in cardiovascular medicine\| PubMed ID: 20211432	2009
Primary contribution to zebrafish heart regeneration by gata4(+) cardiomyocytes. Nature\| PubMed ID: 20336144	2010
Tbx5 and Bmp signaling are essential for proepicardium specification in zebrafish. Circulation research\| PubMed ID: 20413782	2010
The mitochondrial import gene tomm22 is specifically required for hepatocyte survival and provides a liver regeneration model. Disease models & mechanisms\| PubMed ID: 20483998	2010
Hand2 regulates extracellular matrix remodeling essential for gut-looping morphogenesis in zebrafish. Developmental cell\| PubMed ID: 20627079	2010
deLiver'in regeneration: injury response and development. Seminars in liver disease\| PubMed ID: 20665380	2010
Cardiac conduction is required to preserve cardiac chamber morphology. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 20675583	2010
Vertebrate Hedgehog signaling: cilia rule. BMC biology\| PubMed ID: 20687907	2010
Cse1l is a negative regulator of CFTR-dependent fluid secretion. Current biology : CB\| PubMed ID: 20933420	2010
Dynamic glucoregulation and mammalian-like responses to metabolic and developmental disruption in zebrafish. General and comparative endocrinology\| PubMed ID: 20965191	2011
A dual role for ErbB2 signaling in cardiac trabeculation. Development (Cambridge, England)\| PubMed ID: 20978078	2010
Optogenetic control of cardiac function. Science (New York, N.Y.)\| PubMed ID: 21071670	2010
Uhrf1 and Dnmt1 are required for development and maintenance of the zebrafish lens. Developmental biology\| PubMed ID: 21126517	2011
Chromatin remodelling complex dosage modulates transcription factor function in heart development. Nature communications\| PubMed ID: 21304516	2011
Restriction of hepatic competence by Fgf signaling. Development (Cambridge, England)\| PubMed ID: 21385764	2011
A Slit/miR-218/Robo regulatory loop is required during heart tube formation in zebrafish. Development (Cambridge, England)\| PubMed ID: 21385766	2011
Suppression of Ptf1a activity induces acinar-to-endocrine conversion. Current biology : CB\| PubMed ID: 21497092	2011
Iroquois homeobox gene 3 establishes fast conduction in the cardiac His-Purkinje network. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 21825130	2011
Molecular control of endothelial cell behaviour during blood vessel morphogenesis. Nature reviews. Molecular cell biology\| PubMed ID: 21860391	2011
Regulation of intrahepatic biliary duct morphogenesis by Claudin 15-like b. Developmental biology\| PubMed ID: 22020048	2012
Developmental biology: physics adds a twist to gut looping. Current biology : CB\| PubMed ID: 22032191	2011
Analysis of sphingosine-1-phosphate signaling mutants reveals endodermal requirements for the growth but not dorsoventral patterning of jaw skeletal precursors. Developmental biology\| PubMed ID: 22185793	2012
Mutation of zebrafish Snapc4 is associated with loss of the intrahepatic biliary network. Developmental biology\| PubMed ID: 22222761	2012
A monocarboxylate transporter required for hepatocyte secretion of ketone bodies during fasting. Genes & development\| PubMed ID: 22302940	2012
Intrinsic and extrinsic modifiers of the regulative capacity of the developing liver. Mechanisms of development\| PubMed ID: 22313811	2012
Zebrafish in the study of early cardiac development. Circulation research\| PubMed ID: 22427324	2012
The basic helix-loop-helix transcription factor, heart and neural crest derivatives expressed transcript 2, marks hepatic stellate cells in zebrafish: analysis of stellate cell entry into th... Hepatology (Baltimore, Md.)\| PubMed ID: 22488653	2012
Different levels of Notch signaling regulate quiescence, renewal and differentiation in pancreatic endocrine progenitors. Development (Cambridge, England)\| PubMed ID: 22492351	2012
Adenosine signaling promotes regeneration of pancreatic β cells in vivo. Cell metabolism\| PubMed ID: 22608007	2012
Sox9b is a key regulator of pancreaticobiliary ductal system development. PLoS genetics\| PubMed ID: 22719264	2012
Determination of endothelial stalk versus tip cell potential during angiogenesis by H2.0-like homeobox-1. Current biology : CB\| PubMed ID: 22921365	2012
Nodal signaling regulates endodermal cell motility and actin dynamics via Rac1 and Prex1. The Journal of cell biology\| PubMed ID: 22945937	2012
MicroRNA-10 regulates the angiogenic behavior of zebrafish and human endothelial cells by promoting vascular endothelial growth factor signaling. Circulation research\| PubMed ID: 22955733	2012
Whole-organism screening for gluconeogenesis identifies activators of fasting metabolism. Nature chemical biology\| PubMed ID: 23201900	2013
Ubiad1 is an antioxidant enzyme that regulates eNOS activity by CoQ10 synthesis. Cell\| PubMed ID: 23374346	2013
Autophagy induction is a Tor- and Tp53-independent cell survival response in a zebrafish model of disrupted ribosome biogenesis. PLoS genetics\| PubMed ID: 23408911	2013
Hepatic stellate cells in liver development, regeneration, and cancer. The Journal of clinical investigation\| PubMed ID: 23635788	2013
Specification of hepatopancreas progenitors in zebrafish by hnf1ba and wnt2bb. Development (Cambridge, England)\| PubMed ID: 23720049	2013
The perivascular niche regulates breast tumour dormancy. Nature cell biology\| PubMed ID: 23728425	2013
Homeostatic generation of reactive oxygen species protects the zebrafish liver from steatosis. Hepatology (Baltimore, Md.)\| PubMed ID: 23744565	2013
Laminin β1a controls distinct steps during the establishment of digestive organ laterality. Development (Cambridge, England)\| PubMed ID: 23757411	2013
In vivo cardiac reprogramming contributes to zebrafish heart regeneration. Nature\| PubMed ID: 23783515	2013
Metabolic regulation of cellular plasticity in the pancreas. Current biology : CB\| PubMed ID: 23791726	2013
ETS factors regulate Vegf-dependent arterial specification. Developmental cell\| PubMed ID: 23830865	2013
Hepatocyte growth factor signaling in intrapancreatic ductal cells drives pancreatic morphogenesis. PLoS genetics\| PubMed ID: 23935514	2013
Extensive conversion of hepatic biliary epithelial cells to hepatocytes after near total loss of hepatocytes in zebrafish. Gastroenterology\| PubMed ID: 24148620	2014
High-resolution imaging of cardiomyocyte behavior reveals two distinct steps in ventricular trabeculation. Development (Cambridge, England)\| PubMed ID: 24401373	2014
Minor class splicing shapes the zebrafish transcriptome during development. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 24516132	2014
Out with the old, in with the new: reassessing morpholino knockdowns in light of genome editing technology. Development (Cambridge, England)\| PubMed ID: 25100652	2014
Intracardiac flow dynamics regulate atrioventricular valve morphogenesis. Cardiovascular research\| PubMed ID: 25100766	2014
Whole organism high content screening identifies stimulators of pancreatic beta-cell proliferation. PloS one\| PubMed ID: 25117518	2014
Developmental biology: It takes muscle to make blood cells. Nature\| PubMed ID: 25119030	2014
Actin Binding GFP Allows 4D In Vivo Imaging of Myofilament Dynamics in the Zebrafish Heart and the Identification of Erbb2 Signaling as a Remodeling Factor of Myofibril Architecture. Circulation research\| PubMed ID: 25228389	2014
Translational profiling through biotinylation of tagged ribosomes in zebrafish. Development (Cambridge, England)\| PubMed ID: 25231762	2014