Tongguang Wang

Translational Neuroscience Center, National Institutes of Health

Affiliated withNational Institutes of Health

Research Area

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 15	2015
Publication title Cited by 1	2025

Other Publications

Article	Year
NADPH oxidase mediates lipopolysaccharide-induced neurotoxicity and proinflammatory gene expression in activated microglia. The Journal of biological chemistry\| PubMed ID: 14578353	2004
Andrographolide reduces inflammation-mediated dopaminergic neurodegeneration in mesencephalic neuron-glia cultures by inhibiting microglial activation. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 14718612	2004
Neuroprotective effect of dextromethorphan in the MPTP Parkinson's disease model: role of NADPH oxidase. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 14734632	2004
Protective effect of the SOD/catalase mimetic MnTMPyP on inflammation-mediated dopaminergic neurodegeneration in mesencephalic neuronal-glial cultures. Journal of neuroimmunology\| PubMed ID: 14741430	2004
Role of reactive oxygen species in LPS-induced production of prostaglandin E2 in microglia. Journal of neurochemistry\| PubMed ID: 14756815	2004
3-hydroxymorphinan is neurotrophic to dopaminergic neurons and is also neuroprotective against LPS-induced neurotoxicity. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 15596482	2005
Protective effect of dextromethorphan against endotoxic shock in mice. Biochemical pharmacology\| PubMed ID: 15627475	2005
Femtomolar concentrations of dextromethorphan protect mesencephalic dopaminergic neurons from inflammatory damage. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 15790998	2005
Aggregated alpha-synuclein activates microglia: a process leading to disease progression in Parkinson's disease. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 15791003	2005
MPP+-induced COX-2 activation and subsequent dopaminergic neurodegeneration. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 15845609	2005
Viruses and the brain: from inflammation to dementia. Clinical science (London, England : 1979)\| PubMed ID: 16526945	2006
Granzyme B mediates neurotoxicity through a G-protein-coupled receptor. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 16636104	2006
Reactive microgliosis participates in MPP+-induced dopaminergic neurodegeneration: role of 67 kDa laminin receptor. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 16675848	2006
3-Hydroxymorphinan, a metabolite of dextromethorphan, protects nigrostriatal pathway against MPTP-elicited damage both in vivo and in vitro. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 17142799	2006
Interleukin-17 in transverse myelitis and multiple sclerosis. Journal of neuroimmunology\| PubMed ID: 18417225	2008
Activated T-cells inhibit neurogenesis by releasing granzyme B: rescue by Kv1.3 blockers. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 20371822	2010
Rescue of adult hippocampal neurogenesis in a mouse model of HIV neurologic disease. Neurobiology of disease\| PubMed ID: 21146610	2011
HIV immune complexes prevent excitotoxicity by interaction with NMDA receptors. Neurobiology of disease\| PubMed ID: 22940423	2013
Granzyme B-induced neurotoxicity is mediated via activation of PAR-1 receptor and Kv1.3 channel. PloS one\| PubMed ID: 22952817	2012
Cancer regression and neurological toxicity following anti-MAGE-A3 TCR gene therapy. Journal of immunotherapy (Hagerstown, Md. : 1997)\| PubMed ID: 23377668	2013
Blockade of Kv1.3 potassium channels inhibits differentiation and granzyme B secretion of human CD8+ T effector memory lymphocytes. PloS one\| PubMed ID: 23382885	2013
Impaired neurogenesis and neurite outgrowth in an HIV-gp120 transgenic model is reversed by exercise via BDNF production and Cdk5 regulation. Journal of neurovirology\| PubMed ID: 23982957	2013
Derivation of neural stem cells from human adult peripheral CD34+ cells for an autologous model of neuroinflammation. PloS one\| PubMed ID: 24303066	2013
Autism-associated mutation inhibits protein kinase C-mediated neuroligin-4X enhancement of excitatory synapses. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 25675530	2015
Protease-activated receptor-1 activation by granzyme B causes neurotoxicity that is augmented by interleukin-1β. Journal of neuroinflammation\| PubMed ID: 28655310	2017
Isoform-specific cleavage of neuroligin-3 reduces synapse strength. Molecular psychiatry\| PubMed ID: 30242227	2019
Activated T cells induce proliferation of oligodendrocyte progenitor cells via release of vascular endothelial cell growth factor-A. Glia\| PubMed ID: 30500113	2018
A Cluster of Autism-Associated Variants on X-Linked NLGN4X Functionally Resemble NLGN4Y. Neuron\| PubMed ID: 32243781	2020
Regulation of stem cell function and neuronal differentiation by HERV-K via mTOR pathway. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 32669437	2020
Response of human macrophages to gamma radiation is mediated via expression of endogenous retroviruses. PLoS pathogens\| PubMed ID: 33556144	2021
Retroviral Elements in Human Evolution and Neural Development. Journal of experimental neurology\| PubMed ID: 33693440	2021
SMARCB1 deletion in atypical teratoid rhabdoid tumors results in human endogenous retrovirus K (HML-2) expression. Scientific reports\| PubMed ID: 34145313	2021
Fluconazole Is Neuroprotective via Interactions with the IGF-1 Receptor. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics\| PubMed ID: 35831747	2022
Retrotransposon insertions associated with risk of neurologic and psychiatric diseases. EMBO reports\| PubMed ID: 36367221	2023
Human stem cells hold the key to the study of human neural infectious disorders. Experimental neurology\| PubMed ID: 37914567	2024
Mechanism-free repurposing of drugs for C9orf72-related ALS/FTD using large-scale genomic data. Cell genomics\| PubMed ID: 39437787	2024
Building a growing genomic repository for maternal and fetal health through the PING Consortium. Pediatric research\| PubMed ID: 39753885	2025