Robert K. Shepherd

Bionics Institute

Affiliated withBionics Institute The University of Melbourne

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 23	2015

Other Publications

Article	Year
Effects of deafness and cochlear implant use on temporal response characteristics in cat primary auditory cortex. Hearing research\| PubMed ID: 24933111	2014
Chronic placental insufficiency has long-term effects on auditory function in the guinea pig. Hearing research\| PubMed ID: 12062768	2002
A multichannel scala tympani electrode array incorporating a drug delivery system for chronic intracochlear infusion. Hearing research\| PubMed ID: 12361871	2002
Cochlear immunochemistry--a new technique based on gelatin embedding. Journal of neuroscience methods\| PubMed ID: 12951235	2003
Surface microstructure of the perilymphatic space: implications for cochlear implants and cell- or drug-based therapies. Archives of otolaryngology--head & neck surgery\| PubMed ID: 15148170	2004
Long-term sensorineural hearing loss induces functional changes in the rat auditory nerve. The European journal of neuroscience\| PubMed ID: 15579167	2004
Chronic depolarization enhances the trophic effects of brain-derived neurotrophic factor in rescuing auditory neurons following a sensorineural hearing loss. The Journal of comparative neurology\| PubMed ID: 15844207	2005
Cochlear implantation in rats: a new surgical approach. Hearing research\| PubMed ID: 15953521	2005
Exogenous BDNF rescues rat spiral ganglion neurons in vivo. Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology\| PubMed ID: 16151360	2005
Survival of partially differentiated mouse embryonic stem cells in the scala media of the guinea pig cochlea. Journal of the Association for Research in Otolaryngology : JARO\| PubMed ID: 16208453	2005
Clinical application of neurotrophic factors: the potential for primary auditory neuron protection. The European journal of neuroscience\| PubMed ID: 16262651	2005
Effect of interphase gap and pulse duration on electrically evoked potentials is correlated with auditory nerve survival. Hearing research\| PubMed ID: 16644157	2006
Aminoglycoside-induced degeneration of adult spiral ganglion neurons involves differential modulation of tyrosine kinase B and p75 neurotrophin receptor signaling. The American journal of pathology\| PubMed ID: 16877354	2006
Basis of electrical stimulation of the cochlea and the cochlear nucleus. Advances in oto-rhino-laryngology\| PubMed ID: 16891843	2006
Pneumococcal meningitis: development of a new animal model. Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology\| PubMed ID: 16936571	2006
Cortical activation following chronic passive implantation of a wide-field suprachoroidal retinal prosthesis. Journal of neural engineering\| PubMed ID: 24965866	2014
Pneumococcal meningitis threshold model: A potential tool to assess infectious risk of new or existing inner ear surgical interventions. Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology\| PubMed ID: 16980916	2006
Protective effects of local administration of ciprofloxacin on the risk of pneumococcal meningitis after cochlear implantation. The Laryngoscope\| PubMed ID: 17146386	2006
Does cochlear implantation and electrical stimulation affect residual hair cells and spiral ganglion neurons? Hearing research\| PubMed ID: 17258411	2007
Effects of inner ear trauma on the risk of pneumococcal meningitis. Archives of otolaryngology--head & neck surgery\| PubMed ID: 17372082	2007
Threshold shift: effects of cochlear implantation on the risk of pneumococcal meningitis. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery\| PubMed ID: 17418257	2007
Neurotrophic factors and neural prostheses: potential clinical applications based upon findings in the auditory system. IEEE transactions on bio-medical engineering\| PubMed ID: 17551571	2007
Mice deficient for the type II transmembrane serine protease, TMPRSS1/hepsin, exhibit profound hearing loss. The American journal of pathology\| PubMed ID: 17620368	2007
Deafness alters auditory nerve fibre responses to cochlear implant stimulation. The European journal of neuroscience\| PubMed ID: 17650121	2007
Concise review: the potential of stem cells for auditory neuron generation and replacement. Stem cells (Dayton, Ohio)\| PubMed ID: 17656641	2007
Schwann cells revert to non-myelinating phenotypes in the deafened rat cochlea. The European journal of neuroscience\| PubMed ID: 17868369	2007
A fully implantable stimulator for use in small laboratory animals. Journal of neuroscience methods\| PubMed ID: 17897719	2007
Cochlear implants and brain plasticity. Hearing research\| PubMed ID: 17910997	2008
Assessment of the protective effect of pneumococcal vaccination in preventing meningitis after cochlear implantation. Archives of otolaryngology--head & neck surgery\| PubMed ID: 17938321	2007
Meningitis after cochlear implantation. BMJ (Clinical research ed.)\| PubMed ID: 18033888	2007
Cochlear implants stimulate activity-dependent CREB pathway in the deaf auditory cortex: implications for molecular plasticity induced by neural prosthetic devices. Cerebral cortex (New York, N.Y. : 1991)\| PubMed ID: 18063565	2008
Can we prevent cochlear implant recipients from developing pneumococcal meningitis? Clinical infectious diseases : an official publication of the Infectious Diseases Society of America\| PubMed ID: 18171202	2008
Neurotrophins and electrical stimulation for protection and repair of spiral ganglion neurons following sensorineural hearing loss. Hearing research\| PubMed ID: 18243608	2008
The auditory brain--a tribute to Dexter R.F. Irvine. Hearing research\| PubMed ID: 18291607	2008
Promoting neurite outgrowth from spiral ganglion neuron explants using polypyrrole/BDNF-coated electrodes. Journal of biomedical materials research. Part A\| PubMed ID: 18814235	2009
A protocol for cryoembedding the adult guinea pig cochlea for fluorescence immunohistology. Journal of neuroscience methods\| PubMed ID: 18835298	2009
Cochlear implant use following neonatal deafness influences the cochleotopic organization of the primary auditory cortex in cats. The Journal of comparative neurology\| PubMed ID: 18972570	2009
Effects of neonatal partial deafness and chronic intracochlear electrical stimulation on auditory and electrical response characteristics in primary auditory cortex. Hearing research\| PubMed ID: 19703532	2009
Neural prostheses and brain plasticity. Journal of neural engineering\| PubMed ID: 19850976	2009
Special issue on medical bionics. Journal of neural engineering\| PubMed ID: 19861723	2009
Effects of localized neurotrophin gene expression on spiral ganglion neuron resprouting in the deafened cochlea. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 20216530	2010
Evaluation of stimulus parameters and electrode geometry for an effective suprachoroidal retinal prosthesis. Journal of neural engineering\| PubMed ID: 20479521	2010
Bilateral cochlear implantation in the ferret: a novel animal model for behavioral studies. Journal of neuroscience methods\| PubMed ID: 20576507	2010
Examining the auditory nerve fiber response to high rate cochlear implant stimulation: chronic sensorineural hearing loss and facilitation. Journal of neurophysiology\| PubMed ID: 20926607	2010
Pneumococcal meningitis post-cochlear implantation: potential routes of infection and pathophysiology. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery\| PubMed ID: 20970686	2010
Pneumococcal meningitis post-cochlear implantation: preventative measures. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery\| PubMed ID: 20970694	2010
An automated system for rapid evaluation of high-density electrode arrays in neural prostheses. Journal of neural engineering\| PubMed ID: 21493979	2011
Enhanced auditory neuron survival following cell-based BDNF treatment in the deaf guinea pig. PloS one\| PubMed ID: 21525998	2011
The effect of deafness duration on neurotrophin gene therapy for spiral ganglion neuron protection. Hearing research\| PubMed ID: 21557994	2011
Spiral ganglion neuron survival and function in the deafened cochlea following chronic neurotrophic treatment. Hearing research\| PubMed ID: 21762764	2011
Development of a surgical approach for a wide-view suprachoroidal retinal prosthesis: evaluation of implantation trauma. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fÃ¼r klinische und experimentelle Ophthalmologie\| PubMed ID: 21874343	2012
Combining cell-based therapies and neural prostheses to promote neural survival. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics\| PubMed ID: 21904788	2011
Visual cortex responses to suprachoroidal electrical stimulation of the retina: effects of electrode return configuration. Journal of neural engineering\| PubMed ID: 22595310	2012
Nanoporous peptide particles for encapsulating and releasing neurotrophic factors in an animal model of neurodegeneration. Advanced materials (Deerfield Beach, Fla.)\| PubMed ID: 22610659	2012
Challenges for stem cells to functionally repair the damaged auditory nerve. Expert opinion on biological therapy\| PubMed ID: 23094991	2013
Special section on medical bionics. Journal of neural engineering\| PubMed ID: 23186858	2012
Hydrogel limits stem cell dispersal in the deaf cochlea: implications for cochlear implants. Journal of neural engineering\| PubMed ID: 23186887	2012
Neurotrophin gene therapy for sustained neural preservation after deafness. PloS one\| PubMed ID: 23284995	2012
Chronic neurotrophin delivery promotes ectopic neurite growth from the spiral ganglion of deafened cochleae without compromising the spatial selectivity of cochlear implants. The Journal of comparative neurology\| PubMed ID: 23436344	2013
A wide-field suprachoroidal retinal prosthesis is stable and well tolerated following chronic implantation. Investigative ophthalmology & visual science\| PubMed ID: 23611996	2013
Suprachoroidal electrical stimulation: effects of stimulus pulse parameters on visual cortical responses. Journal of neural engineering\| PubMed ID: 23928717	2013
Visual prostheses for the blind. Trends in biotechnology\| PubMed ID: 23953722	2013
Effects of chronic cochlear electrical stimulation after an extended period of profound deafness on primary auditory cortex organization in cats. The European journal of neuroscience\| PubMed ID: 24325274	2014
Development of a surgical procedure for implantation of a prototype suprachoroidal retinal prosthesis. Clinical & experimental ophthalmology\| PubMed ID: 24330322	2014
Measurement of forces at the tip of a cochlear implant during insertion. IEEE transactions on bio-medical engineering\| PubMed ID: 24658242	2014
Gene therapy boosts the bionic ear. Science translational medicine\| PubMed ID: 24760187	2014
Chronic electrical stimulation with a suprachoroidal retinal prosthesis: a preclinical safety and efficacy study. PloS one\| PubMed ID: 24853376	2014
Mesoporous silica supraparticles for sustained inner-ear drug delivery. Small (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 25099026	2014
Safety and efficacy of explanting or replacing suprachoroidal electrode arrays in a feline model. Clinical & experimental ophthalmology\| PubMed ID: 25196241	2014
Mold-templated inorganic-organic hybrid supraparticles for codelivery of drugs. Biomacromolecules\| PubMed ID: 25321318	2014
<i>In vivo</i> and <i>in vitro</i> Comparison of the Charge Injection Capacity of Platinum Macro Electrodes. IEEE transactions on bio-medical engineering\| PubMed ID: 25376031	2014
Evaluation of focused multipolar stimulation for cochlear implants in acutely deafened cats. Journal of neural engineering\| PubMed ID: 25420148	2014
ATP-induced photoreceptor death in a feline model of retinal degeneration. Investigative ophthalmology & visual science\| PubMed ID: 25425300	2014
Cell-based neurotrophin treatment supports long-term auditory neuron survival in the deaf guinea pig. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 25481440	2015
First-in-human trial of a novel suprachoroidal retinal prosthesis. PloS one\| PubMed ID: 25521292	2014
Infrared neural stimulation fails to evoke neural activity in the deaf guinea pig cochlea. Hearing research\| PubMed ID: 25796297	2015
Evaluation of focused multipolar stimulation for cochlear implants in long-term deafened cats. Journal of neural engineering\| PubMed ID: 25834113	2015