Andreas Vogt

Pharmacology and Chemical Biology, University of Pittsburgh Drug Discovery Institute

Affiliated withUniversity of Pittsburgh Drug Discovery Institute

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 48	2010

Other Publications

Article	Year
The antisignaling agent SC-alpha alpha delta 9, 4-(benzyl-(2-[(2,5-diphenyloxazole-4-carbonyl)amino]ethyl)carbamoyl)- 2-decanoylaminobutyric acid, is a structurally unique phospholipid analo... Molecular cancer therapeutics\| PubMed ID: 12481409	2002
Cell-active dual specificity phosphatase inhibitors identified by high-content screening. Chemistry & biology\| PubMed ID: 12954332	2003
Activation of the Raf-1/MEK/Erk kinase pathway by a novel Cdc25 inhibitor in human prostate cancer cells. The Prostate\| PubMed ID: 14673957	2004
A scalable high-content cytotoxicity assay insensitive to changes in mitochondrial metabolic activity. Oncology research\| PubMed ID: 15206493	2004
Discovery and characterization of novel small molecule inhibitors of human Cdc25B dual specificity phosphatase. Molecular pharmacology\| PubMed ID: 15231869	2004
The benzo[c]phenanthridine alkaloid, sanguinarine, is a selective, cell-active inhibitor of mitogen-activated protein kinase phosphatase-1. The Journal of biological chemistry\| PubMed ID: 15753082	2005
Rhodopsin patterning in central photoreceptor cells of the blowfly Calliphora vicina: cloning and characterization of Calliphora rhodopsins Rh3, Rh5 and Rh6. The Journal of experimental biology\| PubMed ID: 15781885	2005
Dual specificity protein phosphatases: therapeutic targets for cancer and Alzheimer's disease. Annual review of pharmacology and toxicology\| PubMed ID: 15822194	2005
Chemical complementation: a definitive phenotypic strategy for identifying small molecule inhibitors of elusive cellular targets. Pharmacology & therapeutics\| PubMed ID: 15925410	2005
Tubulin assembly, taxoid site binding, and cellular effects of the microtubule-stabilizing agent dictyostatin. Biochemistry\| PubMed ID: 16274252	2005
Structure-based design of imidazole-containing peptidomimetic inhibitors of protein farnesyltransferase. Organic & biomolecular chemistry\| PubMed ID: 16446806	2006
Cellular analysis of disorazole C and structure-activity relationship of analogs of the natural product. Chemical biology & drug design\| PubMed ID: 16492150	2006
Novel benzofuran inhibitors of human mitogen-activated protein kinase phosphatase-1. Bioorganic & medicinal chemistry\| PubMed ID: 16698271	2006
Postoperative colonic motility after tropisetron and a standardized meal in patients undergoing conventional colorectal surgery. International journal of colorectal disease\| PubMed ID: 16941175	2007
Discovery of protein kinase phosphatase inhibitors. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 16988418	2007
Regulator of G-protein signalling 3 redirects prototypical Gi-coupled receptors from Rac1 to RhoA activation. Cellular signalling\| PubMed ID: 17300916	2007
Implementation of high-content assay for inhibitors of mitogen-activated protein kinase phosphatases. Methods (San Diego, Calif.)\| PubMed ID: 17532514	2007
Total synthesis and biological evaluation of C16 analogs of (-)-dictyostatin. Journal of medicinal chemistry\| PubMed ID: 17542572	2007
Structure-activity and high-content imaging analyses of novel tubulysins. Chemical biology & drug design\| PubMed ID: 17683369	2007
Sphingosine-1-phosphate and endothelin-1 induce the expression of rgs16 protein in cardiac myocytes by transcriptional activation of the rgs16 gene. Naunyn-Schmiedeberg's archives of pharmacology\| PubMed ID: 18046543	2008
Reduction of airspace after lung resection through controlled paralysis of the diaphragm. European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery\| PubMed ID: 18061470	2008
Cell-based and biochemical structure-activity analyses of analogs of the microtubule stabilizer dictyostatin. Molecular pharmacology\| PubMed ID: 18073274	2008
A cell-active inhibitor of mitogen-activated protein kinase phosphatases restores paclitaxel-induced apoptosis in dexamethasone-protected cancer cells. Molecular cancer therapeutics\| PubMed ID: 18245669	2008
Synthesis and biological evaluation of (-)-dictyostatin and stereoisomers. Tetrahedron\| PubMed ID: 18728696	2007
Human rhomboid family-1 gene RHBDF1 participates in GPCR-mediated transactivation of EGFR growth signals in head and neck squamous cancer cells. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 18832597	2009
Automated image-based phenotypic analysis in zebrafish embryos. Developmental dynamics : an official publication of the American Association of Anatomists\| PubMed ID: 19235725	2009
Automatic algorithm for monitoring systolic pressure variation and difference in pulse pressure. Anesthesia and analgesia\| PubMed ID: 19448207	2009
Evaluation of physical and mental recovery status after elective liver resection. European journal of anaesthesiology\| PubMed ID: 19509504	2009
Crossover comparison of the laryngeal mask supreme and the i-gel in simulated difficult airway scenario in anesthetized patients. Anesthesiology\| PubMed ID: 19512881	2009
Peri-operative adrenocortical response to low-dose (1 microg) ACTH and relation to postoperative complications in patients undergoing elective abdominal surgery. Surgery\| PubMed ID: 19541014	2009
Zebrafish chemical screening reveals an inhibitor of Dusp6 that expands cardiac cell lineages. Nature chemical biology\| PubMed ID: 19578332	2009
Meayamycin inhibits pre-messenger RNA splicing and exhibits picomolar activity against multidrug-resistant cells. Molecular cancer therapeutics\| PubMed ID: 19671752	2009
High-content analysis of cancer-cell-specific apoptosis and inhibition of in vivo angiogenesis by synthetic (-)-pironetin and analogs. Chemical biology & drug design\| PubMed ID: 19691472	2009
An unusual case of self-defense. Cell cycle (Georgetown, Tex.)\| PubMed ID: 19855182	2009
A comparison of micropore membrane inlet mass spectrometry-derived pulmonary shunt measurement with Riley shunt in a porcine model. Anesthesia and analgesia\| PubMed ID: 19923510	2009
Identifying a resistance determinant for the antimitotic natural products disorazole C1 and A1. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 20008956	2010
Observation of ventilation-induced Spo(2) oscillations in pigs: first step to noninvasive detection of cyclic recruitment of atelectasis? Experimental lung research\| PubMed ID: 20497021	2010
Streamlined syntheses of (-)-dictyostatin, 16-desmethyl-25,26-dihydrodictyostatin, and 6-epi-16-desmethyl-25,26-dihydrodictyostatin. Journal of the American Chemical Society\| PubMed ID: 20545347	2010
Emergency skill training--a randomized controlled study on the effectiveness of the 4-stage approach compared to traditional clinical teaching. Resuscitation\| PubMed ID: 21067856	2010
A simplified synthesis of novel dictyostatin analogues with in vitro activity against epothilone B-resistant cells and antiangiogenic activity in zebrafish embryos. Molecular cancer therapeutics\| PubMed ID: 21490306	2011
Disruption of intraflagellar protein transport in photoreceptor cilia causes Leber congenital amaurosis in humans and mice. The Journal of clinical investigation\| PubMed ID: 21606596	2011
Evaluation of spontaneous propulsive movement as a screening tool to detect rescue of Parkinsonism phenotypes in zebrafish models. Neurobiology of disease\| PubMed ID: 21669287	2011
Rapid proteomic remodeling of cardiac tissue caused by total body ionizing radiation. Proteomics\| PubMed ID: 21751382	2011
A high-content screening assay in transgenic zebrafish identifies two novel activators of fgf signaling. Birth defects research. Part C, Embryo today : reviews\| PubMed ID: 21932436	2011
Efficient syntheses of 25,26-dihydrodictyostatin and 25,26-dihydro-6-epi-dictyostatin, two potent new microtubule-stabilizing agents. Beilstein journal of organic chemistry\| PubMed ID: 22043248	2011
Structural and functional protein network analyses predict novel signaling functions for rhodopsin. Molecular systems biology\| PubMed ID: 22108793	2011
A high-throughput FRET-based assay for determination of Atg4 activity. Autophagy\| PubMed ID: 22302004	2012