Nicholas E. Leadbeater

Department of Chemistry, University of Connecticut

Affiliated withUniversity of Connecticut

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 6	2015

Other Publications

Article	Year
A study of the ionic liquid mediated microwave heating of organic solvents. The Journal of organic chemistry\| PubMed ID: 11975584	2002
Microencapsulated VO(acac)2: preparation and use in allylic alcohol epoxidation. Organic letters\| PubMed ID: 11975618	2002
Polymer-bound 1-aryl-3-alkyltriazenes as modular ligands for catalysis. Part 1: synthesis and metal coordination. Bioorganic & medicinal chemistry letters\| PubMed ID: 12086831	2002
Polymer-bound 1-aryl-3-alkyltriazenes as modular ligands for catalysis. Part 2: screening immobilized metal complexes for catalytic activity. Bioorganic & medicinal chemistry letters\| PubMed ID: 12086832	2002
Ligand-free palladium catalysis of the Suzuki reaction in water using microwave heating. Organic letters\| PubMed ID: 12182602	2002
Preparation of polymer-supported ligands and metal complexes for use in catalysis. Chemical reviews\| PubMed ID: 12371884	2002
Polymer-supported metal-phosphine complexes for use as catalysts or linkers in medicinally-oriented organic synthesis. Current medicinal chemistry\| PubMed ID: 12470252	2002
Rapid and amenable suzuki coupling reaction in water using microwave and conventional heating. The Journal of organic chemistry\| PubMed ID: 12558412	2003
Transition-metal-free Suzuki-type coupling reactions. Angewandte Chemie (International ed. in English)\| PubMed ID: 12671982	2003
Transition-metal-free Suzuki-type coupling reactions: scope and limitations of the methodology. The Journal of organic chemistry\| PubMed ID: 12839459	2003
Rapid cyanation of aryl iodides in water using microwave promotion. Organic & biomolecular chemistry\| PubMed ID: 12926385	2003
First examples of transition-metal free Sonogashira-type couplings. Organic letters\| PubMed ID: 14535743	2003
Rapid, easy cyanation of aryl bromides and chlorides using nickel salts in conjunction with microwave promotion. The Journal of organic chemistry\| PubMed ID: 14604393	2003
Microwave-assisted Mannich-type three-component reactions. Molecular diversity\| PubMed ID: 14870842	2003
A reassessment of the transition-metal free suzuki-type coupling methodology. The Journal of organic chemistry\| PubMed ID: 15624918	2005
Microwave-promoted Heck coupling using ultralow metal catalyst concentrations. The Journal of organic chemistry\| PubMed ID: 15730302	2005
Suzuki coupling of aryl chlorides with phenylboronic acid in water, using microwave heating with simultaneous cooling. Organic letters\| PubMed ID: 15901144	2005
Fast, easy, clean chemistry by using water as a solvent and microwave heating: the Suzuki coupling as an illustration. Chemical communications (Cambridge, England)\| PubMed ID: 15957019	2005
Real-time monitoring of microwave-promoted Suzuki coupling reactions using in situ Raman spectroscopy. Organic letters\| PubMed ID: 16986957	2006
Real-time monitoring of microwave-promoted organometallic ligand-substitution reactions using in situ Raman spectroscopy. Chemical communications (Cambridge, England)\| PubMed ID: 17047782	2006
Alkoxycarbonylation of aryl iodides using gaseous carbon monoxide and pre-pressurized reaction vessels in conjunction with microwave heating. Organic & biomolecular chemistry\| PubMed ID: 17164908	2007
Using in situ Raman monitoring as a tool for rapid optimisation and scale-up of microwave-promoted organic synthesis: esterification as an example. Organic & biomolecular chemistry\| PubMed ID: 17315069	2007
Probing the effects of microwave irradiation on enzyme-catalysed organic transformations: the case of lipase-catalysed transesterification reactions. Organic & biomolecular chemistry\| PubMed ID: 17377658	2007
Microwave energy: a versatile tool for the biosciences. Organic & biomolecular chemistry\| PubMed ID: 17406708	2007
In situ Raman spectroscopy as a probe for the effect of power on microwave-promoted Suzuki coupling reactions. Organic & biomolecular chemistry\| PubMed ID: 17700844	2007
Use of Raman spectroscopy as a tool for in situ monitoring of microwave-promoted reactions. Nature protocols\| PubMed ID: 18193016	2008
Microwave-promoted insertion of Group 10 metals into free base porphyrins and chlorins: scope and limitations. Dalton transactions (Cambridge, England : 2003)\| PubMed ID: 18305846	2008
Preparation of nonsymmetrically substituted stilbenes in a one-pot two-step heck strategy using ethene as a reagent. The Journal of organic chemistry\| PubMed ID: 18410149	2008
Use of Raman spectroscopy as an in situ tool to obtain kinetic data for organic transformations. Chemistry (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 18830985	2008
Palladium-catalyzed decarboxylative coupling of aromatic acids with aryl halides or unactivated arenes using microwave heating. Chemical communications (Cambridge, England)\| PubMed ID: 19048139	2008
Testing the validity of microwave-interfaced, in situ Raman spectroscopy as a tool for kinetic studies. Organic letters\| PubMed ID: 19072323	2009
Palladium-catalyzed synthesis of diarylmethanes: exploitation of carbanionic leaving groups. Organic letters\| PubMed ID: 19456122	2009
Assessment and use of two silicon carbide multi-well plates for library synthesis and proteolytic digests using microwave heating. Organic & biomolecular chemistry\| PubMed ID: 19462057	2009
Probing "microwave effects" using Raman spectroscopy. Organic & biomolecular chemistry\| PubMed ID: 19707691	2009
In situ reaction monitoring of microwave-mediated reactions using IR spectroscopy. Chemical communications (Cambridge, England)\| PubMed ID: 20717594	2010
Cross coupling: When is free really free? Nature chemistry\| PubMed ID: 21107360	2010
Titanium-catalyzed esterification and transesterification reactions facilitated using microwave heating. Future medicinal chemistry\| PubMed ID: 21426189	2010
Continuous-flow, palladium-catalysed alkoxycarbonylation reactions using a prototype reactor in which it is possible to load gas and heat simultaneously. Organic & biomolecular chemistry\| PubMed ID: 21850299	2011
Access to dienophilic ene-triketone synthons by oxidation of diketones with an oxoammonium salt. Organic letters\| PubMed ID: 22206582	2012
A Weinreb amide approach to the synthesis of trifluoromethylketones. Chemical communications (Cambridge, England)\| PubMed ID: 22911019	2012
Oxidation of α-trifluoromethyl alcohols using a recyclable oxoammonium salt. The Journal of organic chemistry\| PubMed ID: 22931546	2012
Ask the experts: the challenges and benefits of flow chemistry to optimize drug development. Future medicinal chemistry\| PubMed ID: 23043475	2012
The central role of chemistry in 'quality by design' approaches to drug development. Future medicinal chemistry\| PubMed ID: 23043477	2012
Synthesis of 4-acetamido-2,2,6,6-tetramethylpiperidine-1-oxoammonium tetrafluoroborate and 4-acetamido-(2,2,6,6-tetramethyl-piperidin-1-yl)oxyl and their use in oxidative reactions. Nature protocols\| PubMed ID: 23471111	2013
Oxidative esterification of aldehydes using a recyclable oxoammonium salt. Organic letters\| PubMed ID: 23614873	2013
Raman spectroscopy as a tool for monitoring mesoscale continuous-flow organic synthesis: Equipment interface and assessment in four medicinally-relevant reactions. Beilstein journal of organic chemistry\| PubMed ID: 24062851	2013
Trifluoromethyl ketones: properties, preparation, and application. Chemical communications (Cambridge, England)\| PubMed ID: 24162741	2013
Opening an Aladdin's cave: the Suzuki coupling in a room-temperature ionic liquid. Chemical communications (Cambridge, England)\| PubMed ID: 24383065	2014
Methylenation of perfluoroalkyl ketones using a Peterson olefination approach. The Journal of organic chemistry\| PubMed ID: 24410210	2014
Access to nitriles from aldehydes mediated by an oxoammonium salt. Angewandte Chemie (International ed. in English)\| PubMed ID: 25665019	2015
Oxidative cleavage of allyl ethers by an oxoammonium salt. Organic & biomolecular chemistry\| PubMed ID: 25748071	2015
Toward a Unified Mechanism for Oxoammonium Salt-Mediated Oxidation Reactions: A Theoretical and Experimental Study Using a Hydride Transfer Model. The Journal of organic chemistry\| PubMed ID: 26167866	2015