John H. Boyd

Respiratory and Critical Care Medicine, UBC James Hogg Research Center, St. Paul's Hospital

Affiliated withUBC James Hogg Research Center, St. Paul's Hospital

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2015

Other Publications

Article	Year
Upper airway muscle inflammation and denervation changes in obstructive sleep apnea. American journal of respiratory and critical care medicine\| PubMed ID: 15151922	2004
Cardiac ICAM-1 mediates leukocyte-dependent decreased ventricular contractility in endotoxemic mice. Cardiovascular research\| PubMed ID: 16934241	2006
Toll-like receptors differentially regulate CC and CXC chemokines in skeletal muscle via NF-kappaB and calcineurin. Infection and immunity\| PubMed ID: 16982839	2006
Toll-like receptor stimulation in cardiomyoctes decreases contractility and initiates an NF-kappaB dependent inflammatory response. Cardiovascular research\| PubMed ID: 17054926	2006
Fibrinogen decreases cardiomyocyte contractility through an ICAM-1-dependent mechanism. Critical care (London, England)\| PubMed ID: 18173852	2008
S100A8 and S100A9 mediate endotoxin-induced cardiomyocyte dysfunction via the receptor for advanced glycation end products. Circulation research\| PubMed ID: 18403730	2008
Is there a role for sodium bicarbonate in treating lactic acidosis from shock? Current opinion in critical care\| PubMed ID: 18614899	2008
Vasopressin decreases sepsis-induced pulmonary inflammation through the V2R. Resuscitation\| PubMed ID: 18951114	2008
The role of echocardiography in hemodynamic monitoring. Current opinion in critical care\| PubMed ID: 19346938	2009
Low-dose vasopressin infusion results in increased mortality and cardiac dysfunction following ischemia-reperfusion injury in mice. Critical care (London, England)\| PubMed ID: 19549333	2009
beta2-Adrenergic receptor gene polymorphism is associated with mortality in septic shock. American journal of respiratory and critical care medicine\| PubMed ID: 19850944	2010
Toll-like receptor 4-mediated activation of p38 mitogen-activated protein kinase is a determinant of respiratory virus entry and tropism. Journal of virology\| PubMed ID: 20702616	2010
Inhibition of monocyte chemoattractant protein-1 prevents diaphragmatic inflammation and maintains contractile function during endotoxemia. Critical care (London, England)\| PubMed ID: 20950459	2010
Fluid resuscitation in septic shock: a positive fluid balance and elevated central venous pressure are associated with increased mortality. Critical care medicine\| PubMed ID: 20975548	2011
A single nucleotide polymorphism in NF-κB inducing kinase is associated with mortality in septic shock. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 21257964	2011
Leucyl/cystinyl aminopeptidase gene variants in septic shock. Chest\| PubMed ID: 21330387	2011
Association of angiotensin II type 1 receptor-associated protein gene polymorphism with increased mortality in septic shock. Critical care medicine\| PubMed ID: 21423001	2011
Extracellular heat shock protein 70 induces cardiomyocyte inflammation and contractile dysfunction via TLR2. Circulation journal : official journal of the Japanese Circulation Society\| PubMed ID: 21817814	2011
Globalization of ejection fraction: the pulmonary artery catheter has been outsourced. Critical care medicine\| PubMed ID: 21849834	2011
The Toll-like receptor 9 ligand CPG-C attenuates acute inflammatory cardiac dysfunction. Shock (Augusta, Ga.)\| PubMed ID: 21937956	2011
IL17A genetic variation is associated with altered susceptibility to Gram-positive infection and mortality of severe sepsis. Critical care (London, England)\| PubMed ID: 22026963	2011
Inflammation in myocardial diseases. Circulation research\| PubMed ID: 22223210	2012
A common polymorphism in the 5' region of the human protein c gene binds USF1. Thrombosis research\| PubMed ID: 22425321	2012
Normal-range blood lactate concentration in septic shock is prognostic and predictive. Shock (Augusta, Ga.)\| PubMed ID: 22552014	2012
Toll-like receptors and opportunities for new sepsis therapeutics. Current infectious disease reports\| PubMed ID: 22805995	2012
AA genotype of IL-8 -251A/T is associated with low PaO(2)/FiO(2) in critically ill patients and with increased IL-8 expression. Respirology (Carlton, Vic.)\| PubMed ID: 22897124	2012
One size does not fit all in severe infection: obesity alters outcome, susceptibility, treatment, and inflammatory response. Critical care (London, England)\| PubMed ID: 23786836	2013
A multibiomarker-based outcome risk stratification model for adult septic shock*. Critical care medicine\| PubMed ID: 24335447	2014
Prolonged QTc affects short-term and long-term outcomes in patients with normal left ventricular function undergoing cardiac surgery. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 24485960	2014
The meta-genome of sepsis: host genetics, pathogens and the acute immune response. Journal of innate immunity\| PubMed ID: 24525633	2014
Metagenomics and innate immunity - a unique partnership or a battlefield? Journal of innate immunity\| PubMed ID: 24525698	2014
Small acute increases in serum creatinine are associated with decreased long-term survival in the critically ill. American journal of respiratory and critical care medicine\| PubMed ID: 24601781	2014
Barriers to the effective treatment of sepsis: antimicrobial agents, sepsis definitions, and host-directed therapies. Annals of the New York Academy of Sciences\| PubMed ID: 24797961	2014
Limited echocardiography-guided therapy in subacute shock is associated with change in management and improved outcomes. Journal of critical care\| PubMed ID: 24857642	2014
Serious adverse events associated with vasopressin and norepinephrine infusion in septic shock. Critical care medicine\| PubMed ID: 24919159	2014
Long-term (10-year) mortality of younger previously healthy patients with severe sepsis/septic shock is worse than that of patients with nonseptic critical illness and of the general populat... Critical care medicine\| PubMed ID: 25054672	2014
A functional synonymous coding variant in the IL1RN gene is associated with survival in septic shock. American journal of respiratory and critical care medicine\| PubMed ID: 25089931	2014
Identification of a nonsynonymous polymorphism in the SVEP1 gene associated with altered clinical outcomes in septic shock. Critical care medicine\| PubMed ID: 25188548	2015
PCSK9 is a critical regulator of the innate immune response and septic shock outcome. Science translational medicine\| PubMed ID: 25320235	2014
Once is enough: limited echocardiography in subacute shock. Journal of critical care\| PubMed ID: 25579374	2015
An Endotoxin Tolerance Signature Predicts Sepsis and Organ Dysfunction at Initial Clinical Presentation. EBioMedicine\| PubMed ID: 25685830	2014
VPS13D Gene Variant Is Associated with Altered IL-6 Production and Mortality in Septic Shock. Journal of innate immunity\| PubMed ID: 25896417	2015