Lary C. Walker

Yerkes National Primate Research Center, Emory University

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 26	2010

Other Publications

Article	Year
Axonopathy, tau abnormalities, and dyskinesia, but no neurofibrillary tangles in p25-transgenic mice. The Journal of comparative neurology\| PubMed ID: 11932941	2002
Proteopathy: the next therapeutic frontier? Current opinion in investigational drugs (London, England : 2000)\| PubMed ID: 12090553	2002
Exogenous induction of cerebral beta-amyloidosis in betaAPP-transgenic mice. Peptides\| PubMed ID: 12128081	2002
Deposition of Alzheimer's beta-amyloid is inversely correlated with P-glycoprotein expression in the brains of elderly non-demented humans. Pharmacogenetics\| PubMed ID: 12360104	2002
Xanthomatosis. Journal of neurosurgery\| PubMed ID: 12405396	2002
Alzheimer's Abeta vaccination of rhesus monkeys (Macaca mulatta). Mechanisms of ageing and development\| PubMed ID: 15037022	2004
Alzheimer A beta vaccination of rhesus monkeys (Macaca mulatta). Alzheimer disease and associated disorders\| PubMed ID: 15195463	2004
Aging, gender and APOE isotype modulate metabolism of Alzheimer's Abeta peptides and F-isoprostanes in the absence of detectable amyloid deposits. Journal of neurochemistry\| PubMed ID: 15287908	2004
Proteomic identification of the involvement of the mitochondrial rieske protein in epilepsy. Epilepsia\| PubMed ID: 15730530	2005
Emerging prospects for the disease-modifying treatment of Alzheimer's disease. Biochemical pharmacology\| PubMed ID: 15763538	2005
The role of P-glycoprotein in cerebral amyloid angiopathy; implications for the early pathogenesis of Alzheimer's disease. Current Alzheimer research\| PubMed ID: 15975076	2004
Calcium channel alpha2-delta type 1 subunit is the major binding protein for pregabalin in neocortex, hippocampus, amygdala, and spinal cord: an ex vivo autoradiographic study in alpha2-delt... Brain research\| PubMed ID: 16460711	2006
Cerebrovascular P-glycoprotein expression is decreased in Creutzfeldt-Jakob disease. Acta neuropathologica\| PubMed ID: 16523342	2006
Alzheimer therapeutics-what after the cholinesterase inhibitors? Age and ageing\| PubMed ID: 16644763	2006
Inducible proteopathies. Trends in neurosciences\| PubMed ID: 16806508	2006
Exogenous induction of cerebral beta-amyloidogenesis is governed by agent and host. Science (New York, N.Y.)\| PubMed ID: 16990547	2006
MDR1-P-Glycoprotein (ABCB1) Mediates Transport of Alzheimer's amyloid-beta peptides--implications for the mechanisms of Abeta clearance at the blood-brain barrier. Brain pathology (Zurich, Switzerland)\| PubMed ID: 17610523	2007
The response of the aged brain to stroke: too much, too soon? Current neurovascular research\| PubMed ID: 17691975	2007
Development of transgenic rats producing human beta-amyloid precursor protein as a model for Alzheimer's disease: transgene and endogenous APP genes are regulated tissue-specifically. BMC neuroscience\| PubMed ID: 18302776	2008
Long-term hypothermia reduces infarct volume in aged rats after focal ischemia. Neuroscience letters\| PubMed ID: 18456407	2008
Tauopathy with paired helical filaments in an aged chimpanzee. The Journal of comparative neurology\| PubMed ID: 18481275	2008
Molecular polymorphism of Abeta in Alzheimer's disease. Neurobiology of aging\| PubMed ID: 18619711	2010
Clinico-pathologic function of cerebral ABC transporters - implications for the pathogenesis of Alzheimer's disease. Current Alzheimer research\| PubMed ID: 18690837	2008
The synthesis and structure-activity relationship of substituted N-phenyl anthranilic acid analogs as amyloid aggregation inhibitors. Bioorganic & medicinal chemistry letters\| PubMed ID: 19121939	2009
PIB binding in aged primate brain: enrichment of high-affinity sites in humans with Alzheimer's disease. Neurobiology of aging\| PubMed ID: 19329226	2011
Alzheimer's disease and blood-brain barrier function-Why have anti-beta-amyloid therapies failed to prevent dementia progression? Neuroscience and biobehavioral reviews\| PubMed ID: 19481107	2009
Induction of cerebral beta-amyloidosis: intracerebral versus systemic Abeta inoculation. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19622727	2009
Ovarian aging in squirrel monkeys (Saimiri sciureus). Reproduction (Cambridge, England)\| PubMed ID: 19656956	2009
Deficient high-affinity binding of Pittsburgh compound B in a case of Alzheimer's disease. Acta neuropathologica\| PubMed ID: 19690877	2010
The grandmother effect and the uniqueness of the human aging phenotype. Gerontology\| PubMed ID: 19864883	2010
Mosaic aging. Medical hypotheses\| PubMed ID: 20110150	2010
Days to criterion as an indicator of toxicity associated with human Alzheimer amyloid-beta oligomers. Annals of neurology\| PubMed ID: 20641005	2010
Peripherally applied Abeta-containing inoculates induce cerebral beta-amyloidosis. Science (New York, N.Y.)\| PubMed ID: 20966215	2010
Automated detection of amyloid-Î²-related cortical and subcortical signal changes in a transgenic model of Alzheimer's disease using high-field MRI. Journal of Alzheimer's disease : JAD\| PubMed ID: 20966552	2011
Amyloid by default. Nature neuroscience\| PubMed ID: 21613991	2011
The role of the ATP-binding cassette transporter P-glycoprotein in the transport of Î²-amyloid across the blood-brain barrier. Current pharmaceutical design\| PubMed ID: 21827406	2011
Cerebral amyloid-Î² proteostasis is regulated by the membrane transport protein ABCC1 in mice. The Journal of clinical investigation\| PubMed ID: 21881209	2011
Soluble AÎ² seeds are potent inducers of cerebral Î²-amyloid deposition. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 21994365	2011
Exogenous seeding of cerebral Î²-amyloid deposition in Î²APP-transgenic rats. Journal of neurochemistry\| PubMed ID: 22017494	2012
Pathogenic protein seeding in Alzheimer disease and other neurodegenerative disorders. Annals of neurology\| PubMed ID: 22028219	2011
The presence of AÎ² seeds, and not age per se, is critical to the initiation of AÎ² deposition in the brain. Acta neuropathologica\| PubMed ID: 22101366	2012
Nonhuman Primate Models of Alzheimer-Like Cerebral Proteopathy. Current pharmaceutical design\| PubMed ID: 22288403	2012