Mahendra S. Rao

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 12	2015

Other Publications

Article	Year
Stable expression of the alkaline phosphatase marker gene by neural cells in culture and after transplantation into the CNS using cells derived from a transgenic rat. Experimental neurology\| PubMed ID: 11869033	2002
Isolation of a glial-restricted tripotential cell line from embryonic spinal cord cultures. Glia\| PubMed ID: 11921204	2002
Isolation of stem and precursor cells from fetal tissue. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 11951630	2002
Oligodendrocyte and astrocyte development in rodents: an in situ and immunohistological analysis during embryonic development. Glia\| PubMed ID: 12237841	2002
Grafted lineage-restricted precursors differentiate exclusively into neurons in the adult spinal cord. Experimental neurology\| PubMed ID: 12429183	2002
Properties of a fetal multipotent neural stem cell (NEP cell). Developmental biology\| PubMed ID: 12435354	2002
Transdifferentiation--fact or artifact. Journal of cellular biochemistry\| PubMed ID: 12461772	2003
Disruption of neurogenesis by amyloid beta-peptide, and perturbed neural progenitor cell homeostasis, in models of Alzheimer's disease. Journal of neurochemistry\| PubMed ID: 12472904	2002
Neural stem cells in aging and disease. Journal of cellular and molecular medicine\| PubMed ID: 12611637	2002
Stem cell and precursor cell therapy. Neuromolecular medicine\| PubMed ID: 12622402	2002
Hes1 but not Hes5 regulates an astrocyte versus oligodendrocyte fate choice in glial restricted precursors. Developmental dynamics : an official publication of the American Association of Anatomists\| PubMed ID: 12666205	2003
Nitric oxide acts in a positive feedback loop with BDNF to regulate neural progenitor cell proliferation and differentiation in the mammalian brain. Developmental biology\| PubMed ID: 12798291	2003
The stem-cell menagerie. Trends in neurosciences\| PubMed ID: 12850431	2003
Identifying and tracking neural stem cells. Blood cells, molecules & diseases\| PubMed ID: 12850479	2003
A central nervous system specific mouse model for thanatophoric dysplasia type II. Human molecular genetics\| PubMed ID: 12966031	2003
Distinguishing features of progenitor cells in the late embryonic and adult hippocampus. Developmental neuroscience\| PubMed ID: 12966222	2003
Toward cell replacement therapy: promises and caveats. Experimental neurology\| PubMed ID: 14637081	2003
Transplantation of glial-restricted precursor cells into the adult spinal cord: survival, glial-specific differentiation, and preferential migration in white matter. Glia\| PubMed ID: 14648541	2004
Olig genes are expressed in a heterogeneous population of precursor cells in the developing spinal cord. Glia\| PubMed ID: 14648547	2004
Membrane properties of rat embryonic multipotent neural stem cells. Journal of neurochemistry\| PubMed ID: 14675165	2004
Glutamate transporter expression and function in human glial progenitors. Glia\| PubMed ID: 14730707	2004
Properties of four human embryonic stem cell lines maintained in a feeder-free culture system. Developmental dynamics : an official publication of the American Association of Anatomists\| PubMed ID: 14745950	2004
Long-term culture of human embryonic stem cells in feeder-free conditions. Developmental dynamics : an official publication of the American Association of Anatomists\| PubMed ID: 14745951	2004
Neural stem cell therapy in the aging brain: pitfalls and possibilities. Journal of hematotherapy & stem cell research\| PubMed ID: 14977471	2003
Gene expression in human embryonic stem cell lines: unique molecular signature. Blood\| PubMed ID: 15070671	2004
Differences between human and mouse embryonic stem cells. Developmental biology\| PubMed ID: 15110706	2004
Glial progenitors in the CNS and possible lineage relationships among them. Biology of the cell / under the auspices of the European Cell Biology Organization\| PubMed ID: 15145532	2004
Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. Nature biotechnology\| PubMed ID: 15146197	2004
Properties of pluripotent human embryonic stem cells BG01 and BG02. Stem cells (Dayton, Ohio)\| PubMed ID: 15153607	2004
In search of "stemness". Experimental hematology\| PubMed ID: 15246154	2004
CD44 overexpression by oligodendrocytes: a novel mouse model of inflammation-independent demyelination and dysmyelination. Glia\| PubMed ID: 15293231	2004
CD44 expression identifies astrocyte-restricted precursor cells. Developmental biology\| PubMed ID: 15531362	2004
Dopaminergic differentiation of human embryonic stem cells. Stem cells (Dayton, Ohio)\| PubMed ID: 15536184	2004
Aging and neuronal replacement. Ageing research reviews\| PubMed ID: 15541712	2004
Cellular lifespan and senescence signaling in embryonic stem cells. Aging cell\| PubMed ID: 15569350	2004
Stem sense: a proposal for the classification of stem cells. Stem cells and development\| PubMed ID: 15588501	2004
Glial restricted precursors protect against chronic glutamate neurotoxicity of motor neurons in vitro. Glia\| PubMed ID: 15657939	2005
Karyotypic stability, genotyping, differentiation, feeder-free maintenance, and gene expression sampling in three human embryonic stem cell lines derived prior to August 9, 2001. Stem cells and development\| PubMed ID: 15684826	2004
Monitoring early differentiation events in human embryonic stem cells by massively parallel signature sequencing and expressed sequence tag scan. Stem cells and development\| PubMed ID: 15684837	2004
Endogenous Nkx2.2+/Olig2+ oligodendrocyte precursor cells fail to remyelinate the demyelinated adult rat spinal cord in the absence of astrocytes. Experimental neurology\| PubMed ID: 15698615	2005
Fate of immortalized human neuronal progenitor cells transplanted in rat spinal cord. Archives of neurology\| PubMed ID: 15710850	2005
Characterization of progenitor-cell-specific genes identified by subtractive suppression hybridization. Developmental neuroscience\| PubMed ID: 15711056	2004
BG01V: a variant human embryonic stem cell line which exhibits rapid growth after passaging and reliable dopaminergic differentiation. Restorative neurology and neuroscience\| PubMed ID: 15798361	2004
Functional SDF1 alpha/CXCR4 signaling in the developing spinal cord. Journal of neurochemistry\| PubMed ID: 15816868	2005
Neural precursor cells can be delivered into the injured cervical spinal cord by intrathecal injection at the lumbar cord. Brain research\| PubMed ID: 15910779	2005
Immortalized neural stem cells differ from nonimmortalized cortical neurospheres and cerebellar granule cell progenitors. Experimental neurology\| PubMed ID: 16022860	2005
Sox2 expression defines a heterogeneous population of neurosphere-forming cells in the adult murine brain. Aging cell\| PubMed ID: 16026334	2005
Monitoring differentiation of human embryonic stem cells using real-time PCR. Stem cells (Dayton, Ohio)\| PubMed ID: 16081663	2005
Hyaluronan accumulates in demyelinated lesions and inhibits oligodendrocyte progenitor maturation. Nature medicine\| PubMed ID: 16086023	2005
Comparison of the gene expression profile of undifferentiated human embryonic stem cell lines and differentiating embryoid bodies. BMC developmental biology\| PubMed ID: 16207381	2005
Human umbilical cord matrix stem cells: preliminary characterization and effect of transplantation in a rodent model of Parkinson's disease. Stem cells (Dayton, Ohio)\| PubMed ID: 16223852	2006
Conservation and variation of gene regulation in embryonic stem cells assessed by comparative genomics. Cell biochemistry and biophysics\| PubMed ID: 16244364	2005
Establishing standards for the characterization of human embryonic stem cell lines. Stem cells (Dayton, Ohio)\| PubMed ID: 16253979	2006
Assessing self-renewal and differentiation in human embryonic stem cell lines. Stem cells (Dayton, Ohio)\| PubMed ID: 16293578	2006
Characterization of a new NIH-registered variant human embryonic stem cell line, BG01V: a tool for human embryonic stem cell research. Stem cells (Dayton, Ohio)\| PubMed ID: 16293579	2006
Translational research: toward better characterization of human embryonic stem cell lines. Stem cells (Dayton, Ohio)\| PubMed ID: 16293580	2005
Stem cells: shibboleths of development, part II: Toward a functional definition. Stem cells and development\| PubMed ID: 16305331	2005
NTera2: a model system to study dopaminergic differentiation of human embryonic stem cells. Stem cells and development\| PubMed ID: 16305337	2005
Development of antibodies to human embryonic stem cell antigens. BMC developmental biology\| PubMed ID: 16316465	2005
Brg1 is required for murine neural stem cell maintenance and gliogenesis. Developmental biology\| PubMed ID: 16330018	2006
Neurogenesis in Talpha-1 tubulin transgenic mice during development and after injury. Experimental neurology\| PubMed ID: 16336967	2006
An efficient method for the derivation of mouse embryonic stem cells. Stem cells (Dayton, Ohio)\| PubMed ID: 16339993	2006
A focused microarray to assess dopaminergic and glial cell differentiation from fetal tissue or embryonic stem cells. Stem cells (Dayton, Ohio)\| PubMed ID: 16357341	2006
SDF1alpha/CXCR4 signaling stimulates beta-catenin transcriptional activity in rat neural progenitors. Neuroscience letters\| PubMed ID: 16469439	2006
Estimating human embryonic stem-cell numbers. Lancet\| PubMed ID: 16503462	2006
Differential fate of multipotent and lineage-restricted neural precursors following transplantation into the adult CNS. Neuron glia biology\| PubMed ID: 16520830	2004
Characterization and in vitro differentiation potential of a new human embryonic stem cell line, ReliCellhES1. Differentiation; research in biological diversity\| PubMed ID: 16533307	2006
How many human embryonic stem cell lines are sufficient? A U.S. perspective. Stem cells (Dayton, Ohio)\| PubMed ID: 16543487	2006
Are there morally acceptable alternatives to blastocyst derived ESC? Journal of cellular biochemistry\| PubMed ID: 16598787	2006
Massively parallel signature sequencing profiling of fetal human neural precursor cells. Stem cells and development\| PubMed ID: 16646669	2006
Transcriptome coexpression map of human embryonic stem cells. BMC genomics\| PubMed ID: 16670017	2006
Genome wide profiling of human embryonic stem cells (hESCs), their derivatives and embryonal carcinoma cells to develop base profiles of U.S. Federal government approved hESC lines. BMC developmental biology\| PubMed ID: 16672070	2006
Embryonic stem cell research and U.S. policy. Stem cells (Dayton, Ohio)\| PubMed ID: 16687466	2006
Cytoplasmic translocation of Olig2 in adult glial progenitors marks the generation of reactive astrocytes following autoimmune inflammation. Experimental neurology\| PubMed ID: 16814281	2006
Inflammation stimulates myelination by transplanted oligodendrocyte precursor cells. Glia\| PubMed ID: 16856149	2006
Derivation and characterization of neuronal precursors and dopaminergic neurons from human embryonic stem cells in vitro. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 16881516	2006
Designing, testing, and validating a microarray for stem cell characterization. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 16881521	2006
Massively parallel signature sequencing. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 16881523	2006
Large-scale analysis of neural stem cells and progenitor cells. Neuro-degenerative diseases\| PubMed ID: 16909045	2006
A molecular scheme for improved characterization of human embryonic stem cell lines. BMC biology\| PubMed ID: 16919167	2006
Schwann cell-like differentiation by adult oligodendrocyte precursor cells following engraftment into the demyelinated spinal cord is BMP-dependent. Glia\| PubMed ID: 16921543	2006
The therapeutic potential of embryonic stem cells: A focus on stem cell stability. Current opinion in molecular therapeutics\| PubMed ID: 16955697	2006
Mired in the quagmire of uncertainty: The "catch-22" of embryonic stem cell research. Stem cells and development\| PubMed ID: 16978053	2006
Cross-species transcriptional profiles establish a functional portrait of embryonic stem cells. Genomics\| PubMed ID: 17055697	2007
Mechanisms controlling embryonic stem cell self-renewal and differentiation. Critical reviews in eukaryotic gene expression\| PubMed ID: 17073552	2006
An in vitro model of human dopaminergic neurons derived from embryonic stem cells: MPP+ toxicity and GDNF neuroprotection. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology\| PubMed ID: 17109014	2006
Human embryonic stem cells. Neurosurgery clinics of North America\| PubMed ID: 17244549	2007
Whole genome analysis of human neural stem cells derived from embryonic stem cells and stem and progenitor cells isolated from fetal tissue. Stem cells (Dayton, Ohio)\| PubMed ID: 17272497	2007
Stem cell myths. Philosophical transactions of the Royal Society of London. Series B, Biological sciences\| PubMed ID: 17284414	2008
Qualification of embryonal carcinoma 2102Ep as a reference for human embryonic stem cell research. Stem cells (Dayton, Ohio)\| PubMed ID: 17284651	2007
Truncated tyrosine kinase B brain-derived neurotrophic factor receptor directs cortical neural stem cells to a glial cell fate by a novel signaling mechanism. Journal of neurochemistry\| PubMed ID: 17286628	2007
Stage-dependent Olig2 expression in motor neurons and oligodendrocytes differentiated from embryonic stem cells. Stem cells and development\| PubMed ID: 17348811	2007
Revisiting the astrocyte-oligodendrocyte relationship in the adult CNS. Progress in neurobiology\| PubMed ID: 17448587	2007
A panel of tests to standardize the characterization of human embryonic stem cells. Regenerative medicine\| PubMed ID: 17465750	2007
Increased dentate neurogenesis after grafting of glial restricted progenitors or neural stem cells in the aging hippocampus. Stem cells (Dayton, Ohio)\| PubMed ID: 17510219	2007
Evidence that nucleocytoplasmic Olig2 translocation mediates brain-injury-induced differentiation of glial precursors to astrocytes. Journal of neuroscience research\| PubMed ID: 17510983	2007
Impaired SDF1/CXCR4 signaling in glial progenitors derived from SOD1(G93A) mice. Journal of neuroscience research\| PubMed ID: 17567884	2007
Disease progression after bone marrow transplantation in a model of multiple sclerosis is associated with chronic microglial and glial progenitor response. Journal of neuropathology and experimental neurology\| PubMed ID: 17620989	2007
Self-renewal of human embryonic stem cells requires insulin-like growth factor-1 receptor and ERBB2 receptor signaling. Blood\| PubMed ID: 17761519	2007
The microenvironment of the embryonic neural stem cell: lessons from adult niches? Developmental dynamics : an official publication of the American Association of Anatomists\| PubMed ID: 17937403	2007
Patterns of laminins and integrins in the embryonic ventricular zone of the CNS. The Journal of comparative neurology\| PubMed ID: 17948866	2007
Creation of engineered human embryonic stem cell lines using phiC31 integrase. Stem cells (Dayton, Ohio)\| PubMed ID: 17962703	2008
Adult glial precursor proliferation in mutant SOD1G93A mice. Glia\| PubMed ID: 18023016	2008
A large-scale proteomic analysis of human embryonic stem cells. BMC genomics\| PubMed ID: 18162134	2007
Gene expression profile of neuronal progenitor cells derived from hESCs: activation of chromosome 11p15.5 and comparison to human dopaminergic neurons. PloS one\| PubMed ID: 18183302	2008
Generation and transplantation of dopaminergic neurons derived from embryonic stem cells. Current stem cell research & therapy\| PubMed ID: 18220899	2007
Stem cells for the treatment of neurological disorders. CNS & neurological disorders drug targets\| PubMed ID: 18289036	2008
PDGF, TGF-beta, and FGF signaling is important for differentiation and growth of mesenchymal stem cells (MSCs): transcriptional profiling can identify markers and signaling pathways importan... Blood\| PubMed ID: 18332228	2008
Isolation of neural stem and precursor cells from rodent tissue. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 18369748	2008
Controlled genetic modification of stem cells for developing drug discovery tools and novel therapeutic applications. Current opinion in molecular therapeutics\| PubMed ID: 18535927	2008
Regulatory networks define phenotypic classes of human stem cell lines. Nature\| PubMed ID: 18724358	2008
Cell-extracellular matrix interactions regulate neural differentiation of human embryonic stem cells. BMC developmental biology\| PubMed ID: 18808690	2008
Evolutionarily conserved transcriptional co-expression guiding embryonic stem cell differentiation. PloS one\| PubMed ID: 18923680	2008
Focal transplantation-based astrocyte replacement is neuroprotective in a model of motor neuron disease. Nature neuroscience\| PubMed ID: 18931666	2008
Expression profiling of human glial precursors. BMC developmental biology\| PubMed ID: 18947415	2008
Generation of platform human embryonic stem cell lines that allow efficient targeting at a predetermined genomic location. Stem cells and development\| PubMed ID: 19355838	2009
Neural transplantation and stem cells. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 19378192	2009
Self-renewal and differentiation capabilities are variable between human embryonic stem cell lines I3, I6 and BG01V. BMC cell biology\| PubMed ID: 19500347	2009
A targeted neuroglial reporter line generated by homologous recombination in human embryonic stem cells. Stem cells (Dayton, Ohio)\| PubMed ID: 19544414	2009
Developing safe therapies from human pluripotent stem cells. Nature biotechnology\| PubMed ID: 19587662	2009
Xeno-free defined conditions for culture of human embryonic stem cells, neural stem cells and dopaminergic neurons derived from them. PloS one\| PubMed ID: 19597550	2009
beta1 integrin maintains integrity of the embryonic neocortical stem cell niche. PLoS biology\| PubMed ID: 19688041	2009
Identification by automated screening of a small molecule that selectively eliminates neural stem cells derived from hESCs but not dopamine neurons. PloS one\| PubMed ID: 19774075	2009
Stage-specific role for shh in dopaminergic differentiation of human embryonic stem cells induced by stromal cells. Stem cells and development\| PubMed ID: 19788370	2010
Human cord blood stem cell applications in cell therapy. Journal of stem cells\| PubMed ID: 20232595	2009
Markers of murine embryonic and neural stem cells, neurons and astrocytes: reference points for developmental neurotoxicity testing. ALTEX\| PubMed ID: 20390237	2010
Global Characterization and Genomic Stability of Human MultiStem, A Multipotent Adult Progenitor Cell. Journal of stem cells\| PubMed ID: 20498688	2009
A novel serum-free medium for the expansion of human mesenchymal stem cells. Stem cell research & therapy\| PubMed ID: 20504289	2010
Efficient generation of functional dopaminergic neurons from human induced pluripotent stem cells under defined conditions. Stem cells (Dayton, Ohio)\| PubMed ID: 20715183	2010
Seeing is believing: are cancer stem cells the Loch Ness monster of tumor biology? Stem cell reviews\| PubMed ID: 20957452	2011
Mesenchymal stem cell assays and applications. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 21431506	2011
Concise review: non-cell autonomous reprogramming: a nucleic acid-free approach to induction of pluripotency. Stem cells (Dayton, Ohio)\| PubMed ID: 21544901	2011
Chromatin insulator elements block transgene silencing in engineered human embryonic stem cell lines at a defined chromosome 13 locus. Stem cells and development\| PubMed ID: 21699412	2012
Funding translational work in cell-based therapy. Cell stem cell\| PubMed ID: 21726828	2011
Cell-based therapy for neural disorders--anticipating challenges. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics\| PubMed ID: 21901585	2011
Human glial-restricted progenitor transplantation into cervical spinal cord of the SOD1 mouse model of ALS. PloS one\| PubMed ID: 21998733	2011
Novel live alkaline phosphatase substrate for identification of pluripotent stem cells. Stem cell reviews\| PubMed ID: 22426885	2012
Stromal factors SDF1α, sFRP1, and VEGFD induce dopaminergic neuron differentiation of human pluripotent stem cells. Journal of neuroscience research\| PubMed ID: 22535492	2012
Assessing iPSC reprogramming methods for their suitability in translational medicine. Journal of cellular biochemistry\| PubMed ID: 22573568	2012
Cell therapy in critical limb ischemia: current developments and future progress. Cytotherapy\| PubMed ID: 22731756	2012
Evaluation of cholesterol reduction activity of methyl-β-cyclodextrin using differentiated human neurons and astrocytes. Journal of biomolecular screening\| PubMed ID: 22923786	2012
Nucleic acid and non-nucleic acid-based reprogramming of adult limbal progenitors to pluripotency. PloS one\| PubMed ID: 23056428	2012
Steering a new course for stem cell research: NIH's intramural Center for Regenerative Medicine. Stem cells translational medicine\| PubMed ID: 23197635	2012
Human neural crest stem cells derived from human ESCs and induced pluripotent stem cells: induction, maintenance, and differentiation into functional schwann cells. Stem cells translational medicine\| PubMed ID: 23197806	2012
Efficient generation of astrocytes from human pluripotent stem cells in defined conditions. Stem cells (Dayton, Ohio)\| PubMed ID: 23341249	2013
Using human pluripotent stem cell-derived dopaminergic neurons to evaluate candidate Parkinson's disease therapeutic agents in MPP+ and rotenone models. Journal of biomolecular screening\| PubMed ID: 23364514	2013
A review of the methods for human iPSC derivation. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 23546745	2013
Optimizing dopaminergic differentiation of pluripotent stem cells for the manufacture of dopaminergic neurons for transplantation. Cytotherapy\| PubMed ID: 23664011	2013
Pluripotent stem cells in translation: a Food and Drug Administration-National Institutes of Health collaboration. Stem cells translational medicine\| PubMed ID: 23757505	2013
hESC-derived Olig2+ progenitors generate a subtype of astroglia with protective effects against ischaemic brain injury. Nature communications\| PubMed ID: 23880652	2013
Tumorigenicity as a clinical hurdle for pluripotent stem cell therapies. Nature medicine\| PubMed ID: 23921754	2013
LULL(ed) into complacency: a perspective on licenses and stem cell translational science. Stem cell research & therapy\| PubMed ID: 23953837	2013
Functional screening assays with neurons generated from pluripotent stem cell-derived neural stem cells. Journal of biomolecular screening\| PubMed ID: 24019252	2014
Genome wide profiling of dopaminergic neurons derived from human embryonic and induced pluripotent stem cells. Stem cells and development\| PubMed ID: 24074155	2014
RISC in PD: the impact of microRNAs in Parkinson's disease cellular and molecular pathogenesis. Frontiers in molecular neuroscience\| PubMed ID: 24312000	2013
Comparison of the molecular profiles of human embryonic and induced pluripotent stem cells of isogenic origin. Stem cell research\| PubMed ID: 24374290	2014
Soliciting strategies for developing cell-based reference materials to advance mesenchymal stromal cell research and clinical translation. Stem cells and development\| PubMed ID: 24422625	2014
Genetic Modification in Human Pluripotent Stem Cells by Homologous Recombination and CRISPR/Cas9 System. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 24615461	2014
Stable enhanced green fluorescent protein expression after differentiation and transplantation of reporter human induced pluripotent stem cells generated by AAVS1 transcription activator-lik... Stem cells translational medicine\| PubMed ID: 24833591	2014
Survival and engraftment of dopaminergic neurons manufactured by a Good Manufacturing Practice-compatible process. Cytotherapy\| PubMed ID: 25065637	2014
Compounds with species and cell type specific toxicity identified in a 2000 compound drug screen of neural stem cells and rat mixed cortical neurons. Neurotoxicology\| PubMed ID: 25454721	2014
Banking on iPSC- Is it Doable and is it Worthwhile. Stem cell reviews\| PubMed ID: 25516409	2014
Need for DISCUSS(ion). Stem cells translational medicine\| PubMed ID: 25614444	2015