F. Edward Dudek

Department of Neurosurgery, University of Utah

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 26	2015

Other Publications

Article	Year
Absence of temporal lobe epilepsy pathology in dogs with medically intractable epilepsy. Journal of veterinary internal medicine / American College of Veterinary Internal Medicine\| PubMed ID: 11822812	2002
Network interactions mediated by new excitatory connections between CA1 pyramidal cells in rats with kainate-induced epilepsy. Journal of neurophysiology\| PubMed ID: 11877537	2002
Episodic bursting activity and response to excitatory amino acids in acutely dissociated gonadotropin-releasing hormone neurons genetically targeted with green fluorescent protein. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 11896170	2002
The course of cellular alterations associated with the development of spontaneous seizures after status epilepticus. Progress in brain research\| PubMed ID: 12143370	2002
Reassessment of the effects of cycloheximide on mossy fiber sprouting and epileptogenesis in the pilocarpine model of temporal lobe epilepsy. Journal of neurophysiology\| PubMed ID: 12364529	2002
The search for animal models of epileptogenesis and pharmacoresistance: are there biologic barriers to simple validation strategies? Epilepsia\| PubMed ID: 12423376	2002
Effects of fluoxetine and TFMPP on spontaneous seizures in rats with pilocarpine-induced epilepsy. Epilepsia\| PubMed ID: 12423383	2002
GABA receptor-mediated inhibition of neuronal activity in rat SCN in vitro: pharmacology and influence of circadian phase. Journal of neurophysiology\| PubMed ID: 12750413	2003
Riluzole-sensitive slowly inactivating sodium current in rat suprachiasmatic nucleus neurons. Journal of neurophysiology\| PubMed ID: 14573554	2004
Mechanism of irregular firing of suprachiasmatic nucleus neurons in rat hypothalamic slices. Journal of neurophysiology\| PubMed ID: 14715720	2004
Increased excitatory synaptic activity and local connectivity of hippocampal CA1 pyramidal cells in rats with kainate-induced epilepsy. Journal of neurophysiology\| PubMed ID: 15084640	2004
Cortical Dysplasia and Epileptogenesis: Models and Mechanisms. Epilepsy currents / American Epilepsy Society\| PubMed ID: 15309033	2001
New Evidence for an Important Role of Endogenous GABA in Seizure Generation in the Immature Hippocampus. Epilepsy currents / American Epilepsy Society\| PubMed ID: 15309060	2003
High-frequency Oscillations and Neocortical Seizures: Do They Have a Role in Seizure Onset, and Which Mechanisms Generate Them? Epilepsy currents / American Epilepsy Society\| PubMed ID: 15309065	2003
Single-gene Mutation Leads to Localized Disruption of Cortical Interneuron Development and Increased Seizure Susceptibility. Epilepsy currents / American Epilepsy Society\| PubMed ID: 15309067	2003
Does Neuroprotection Prevent Epileptogenesis? Epilepsy currents / American Epilepsy Society\| PubMed ID: 15309090	2003
Synaptic Reorganization in an Experimental Model of Posttraumatic Epilepsy. Epilepsy currents / American Epilepsy Society\| PubMed ID: 15309118	2002
The Epileptic Neuron Redux. Epilepsy currents / American Epilepsy Society\| PubMed ID: 15309124	2002
Gap Junctions and Fast Oscillations: A Role in Seizures and Epileptogenesis? Epilepsy currents / American Epilepsy Society\| PubMed ID: 15309144	2002
Role of Glial Cells in Seizures and Epilepsy: Intracellular Calcium Oscillations sn Spatial Buffering. Epilepsy currents / American Epilepsy Society\| PubMed ID: 15309145	2002
Selective Inhibitory Interneuron Loss Produces Chronic Hippocampal Hyperexcitability. Epilepsy currents / American Epilepsy Society\| PubMed ID: 15309178	2002
Neuropeptide Y May Be an Endogenous Anticonvulsant in Hippocampus. Epilepsy currents / American Epilepsy Society\| PubMed ID: 15309180	2002
Zinc and Epileptogenesis. Epilepsy currents / American Epilepsy Society\| PubMed ID: 15309193	2001
GluR5 Kainate Receptors and Topiramate: A New Site of Action for Antiepileptic Drugs? Epilepsy currents / American Epilepsy Society\| PubMed ID: 15346138	2004
Does Hippocampal Neurogenesis after Kainate-induced Apoptosis In Neonatal Rats Replace Lost Neurons? Epilepsy currents / American Epilepsy Society\| PubMed ID: 15346162	2003
Epilepsy and synaptic reorganization in a perinatal rat model of hypoxia-ischemia. Epilepsia\| PubMed ID: 15461675	2004
Hyperpolarization-activated Cation Channels in Human and Experimental Epilepsy: Do They Play a Role in Epileptogenesis? Epilepsy currents / American Epilepsy Society\| PubMed ID: 15562309	2004
Update on connexins and gap junctions in neurons and glia in the mammalian nervous system. Brain research. Brain research reviews\| PubMed ID: 15572172	2004
Electrophysiological evidence using focal flash photolysis of caged glutamate that CA1 pyramidal cells receive excitatory synaptic input from the subiculum. Journal of neurophysiology\| PubMed ID: 15601737	2005
Use of chronic epilepsy models in antiepileptic drug discovery: the effect of topiramate on spontaneous motor seizures in rats with kainate-induced epilepsy. Epilepsia\| PubMed ID: 15660763	2005
5-HT1B receptor-mediated presynaptic inhibition of GABA release in the suprachiasmatic nucleus. Journal of neurophysiology\| PubMed ID: 15716370	2005
Changes in mIPSCs and sIPSCs after kainate treatment: evidence for loss of inhibitory input to dentate granule cells and possible compensatory responses. Journal of neurophysiology\| PubMed ID: 15772233	2005
Loss of GABAergic Interneurons in Seizure-induced Epileptogenesis. Epilepsy currents / American Epilepsy Society\| PubMed ID: 15902313	2003
Noise of the slowly inactivating Na current in suprachiasmatic nucleus neurons. Neuroreport\| PubMed ID: 15931073	2005
Detection of increased local excitatory circuits in the hippocampus during epileptogenesis using focal flash photolysis of caged glutamate. Epilepsia\| PubMed ID: 15987262	2005
Seizure-induced neurogenesis and epilepsy: involvement of ectopic granule cells? Epilepsy currents / American Epilepsy Society\| PubMed ID: 16059464	2004
The epileptic GABA(A) receptor: a target for epileptogenesis and for new AEDs? Epilepsy currents / American Epilepsy Society\| PubMed ID: 16059494	2004
Mossy fiber sprouting and recurrent excitation: direct electrophysiologic evidence and potential implications. Epilepsy currents / American Epilepsy Society\| PubMed ID: 16059495	2004
Is there a "critical period" for intervention in posttraumatic epilepsy? Epilepsy currents / American Epilepsy Society\| PubMed ID: 16059518	2004
Do interictal spikes drive epileptogenesis? The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry\| PubMed ID: 16061513	2005
Regulation of brain water: is there a role for aquaporins in epilepsy? Epilepsy currents / American Epilepsy Society\| PubMed ID: 16145616	2005
Are altered excitatory synapses found in neuronal migration disorders? Epilepsy currents / American Epilepsy Society\| PubMed ID: 16175215	2005
Efficient unsupervised algorithms for the detection of seizures in continuous EEG recordings from rats after brain injury. Journal of neuroscience methods\| PubMed ID: 16337006	2006
Chronic cortical injury and epileptogensis: a possible role for intracellular chloride homeostasis. Epilepsy currents / American Epilepsy Society\| PubMed ID: 16372061	2005
The hyperinhibition hypothesis in epileptogenesis: an assessment of the evidence. Epilepsy currents / American Epilepsy Society\| PubMed ID: 16477315	2006
Epilepsy and reproductive disorders: the role of the gonadotropin-releasing hormone network. Epilepsy & behavior : E&B\| PubMed ID: 16504591	2006
The use of radiotelemetry to evaluate electrographic seizures in rats with kainate-induced epilepsy. Journal of neuroscience methods\| PubMed ID: 16564574	2006
Activation of Fos during spontaneous hippocampal seizures in a model of temporal lobe epilepsy. Epilepsy currents / American Epilepsy Society\| PubMed ID: 16604204	2006
Changes in mIPSCs and sIPSCs after kainate treatment: status epilepticus-induced neuronal loss or direct activation of kainate receptors? Journal of neurophysiology\| PubMed ID: 16672302	2006
How independent are initiation, propagation, and termination of epileptiform activity? Epilepsy currents / American Epilepsy Society\| PubMed ID: 16761072	2006
Single-neuron activity and imaging during epileptogenesis: what can be seen and how best to see it? Epilepsy currents / American Epilepsy Society\| PubMed ID: 17260037	2006
Interictal spikes and epileptogenesis. Epilepsy currents / American Epilepsy Society\| PubMed ID: 17260059	2006
Laser scanning photostimulation: new evidence for enhanced recurrent excitation in a model of posttraumatic epilepsy. Epilepsy currents / American Epilepsy Society\| PubMed ID: 17260064	2006
How does the balance of excitation and inhibition shift during epileptogenesis? Epilepsy currents / American Epilepsy Society\| PubMed ID: 17520084	2007
Anticonvulsant effects of carbamazepine on spontaneous seizures in rats with kainate-induced epilepsy: comparison of intraperitoneal injections with drug-in-food protocols. Epilepsia\| PubMed ID: 17711461	2007
Unmasking recurrent excitation generated by mossy fiber sprouting in the epileptic dentate gyrus: an emergent property of a complex system. Progress in brain research\| PubMed ID: 17765737	2007
Epileptogenesis in the dentate gyrus: a critical perspective. Progress in brain research\| PubMed ID: 17765749	2007
Development of spontaneous seizures after experimental status epilepticus: implications for understanding epileptogenesis. Epilepsia\| PubMed ID: 17910596	2007
Neuropathogical features of a rat model for perinatal hypoxic-ischemic encephalopathy with associated epilepsy. The Journal of comparative neurology\| PubMed ID: 17948865	2007
Calcium currents burst back: a possible role for dendrites in epileptogenesis. Epilepsy currents / American Epilepsy Society\| PubMed ID: 17998977	2007
Antiepileptogenesis Therapy with Levetiracetam: Data from Kindling versus Status Epilepticus Models. Epilepsy currents / American Epilepsy Society\| PubMed ID: 18265888	2008
Circadian difference in firing rate of isolated rat suprachiasmatic nucleus neurons. Neuroscience letters\| PubMed ID: 18406526	2008
Chemoconvulsant model of chronic spontaneous seizures. Current protocols in neuroscience / editorial board, Jacqueline N. Crawley ... [et al.]\| PubMed ID: 18428628	2005
In search of a new and improved target for antiepileptic drugs: sialic acid? Epilepsy currents / American Epilepsy Society\| PubMed ID: 18488062	2008
A new potential AED, carisbamate, substantially reduces spontaneous motor seizures in rats with kainate-induced epilepsy. Epilepsia\| PubMed ID: 18494790	2008
On the role of calcium and potassium currents in circadian modulation of firing rate in rat suprachiasmatic nucleus neurons: multielectrode dish analysis. Neuroscience research\| PubMed ID: 18602427	2008
NMDA receptor-mediated long-term alterations in epileptiform activity in experimental chronic epilepsy. Neuropharmacology\| PubMed ID: 18930747	2009
Single and repetitive paired-pulse suppression: a parametric analysis and assessment of usefulness in epilepsy research. Epilepsia\| PubMed ID: 19170733	2009
Development of spontaneous recurrent seizures after kainate-induced status epilepticus. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 19228963	2009
Commentary: a skeptical view of experimental gene therapy to block epileptogenesis. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics\| PubMed ID: 19332326	2009
Is modulation of cortical synapses after brain trauma homeostatic? Or, since when is epilepsy normal? Epilepsy currents / American Epilepsy Society\| PubMed ID: 19421381	2009
Microseizures in human neocortex: a role for ultra-small seizures? Epilepsy currents / American Epilepsy Society\| PubMed ID: 19826511	2009
EEG spike activity precedes epilepsy after kainate-induced status epilepticus. Epilepsia\| PubMed ID: 19845739	2010
Both synaptic and intrinsic mechanisms underlie the different properties of population bursts in the hippocampal CA3 area of immature versus adult rats. The Journal of physiology\| PubMed ID: 19884320	2009
Epileptogenesis: a new twist on the balance of excitation and inhibition. Epilepsy currents / American Epilepsy Society\| PubMed ID: 19936137	2009
Continuous electroencephalographic monitoring with radio-telemetry in a rat model of perinatal hypoxia-ischemia reveals progressive post-stroke epilepsy. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 20053921	2010
The effect of the cannabinoid-receptor antagonist, SR141716, on the early stage of kainate-induced epileptogenesis in the adult rat. Epilepsia\| PubMed ID: 20618417	2010
Counterpoint to "what is an epileptic seizure?" by D'Ambrosio and Miller. Epilepsy currents / American Epilepsy Society\| PubMed ID: 20697504	2010
Is neuronal death necessary for acquired epileptogenesis in the immature brain? Epilepsy currents / American Epilepsy Society\| PubMed ID: 20697505	2010
Primary and secondary mechanisms of epileptogenesis in the temporal lobe: there is a before and an after. Epilepsy currents / American Epilepsy Society\| PubMed ID: 20944823	2010
Axon sprouting and synaptic reorganization of GABAergic interneurons: a focused look at a general question. Epilepsy currents / American Epilepsy Society\| PubMed ID: 20944824	2010
Repetitive perforant-path stimulation induces epileptiform bursts in minislices of dentate gyrus from rats with kainate-induced epilepsy. Journal of neurophysiology\| PubMed ID: 21148094	2011
Interictal spikes: harbingers or causes of epilepsy? Neuroscience letters\| PubMed ID: 21458535	2011
The time course of acquired epilepsy: implications for therapeutic intervention to suppress epileptogenesis. Neuroscience letters\| PubMed ID: 21458536	2011
A once-per-day, drug-in-food protocol for prolonged administration of antiepileptic drugs in animal models. Epilepsia\| PubMed ID: 22092257	2012
Seizure probability in animal models of acquired epilepsy: a perspective on the concept of the preictal state. Epilepsy research\| PubMed ID: 22094446	2011
Mechanisms of Seizure-Induced Inflammation of the Brain: Many Possible Roles for Neuronal COX-2. Epilepsy currents / American Epilepsy Society\| PubMed ID: 22688923	2012
Finding a better drug for epilepsy: preclinical screening strategies and experimental trial design. Epilepsia\| PubMed ID: 22708847	2012
Unique signaling profiles of positive allosteric modulators of metabotropic glutamate receptor subtype 5 determine differences in in vivo activity. Biological psychiatry\| PubMed ID: 23140665	2013
Inhibition of the prostaglandin receptor EP2 following status epilepticus reduces delayed mortality and brain inflammation. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23401547	2013
Epilepsy therapy development: technical and methodologic issues in studies with animal models. Epilepsia\| PubMed ID: 23909850	2013
Issues related to development of antiepileptogenic therapies. Epilepsia\| PubMed ID: 23909852	2013
Epilepsy biomarkers. Epilepsia\| PubMed ID: 23909854	2013
Valnoctamide enhances phasic inhibition: a potential target mechanism for the treatment of benzodiazepine-refractory status epilepticus. Epilepsia\| PubMed ID: 24995528	2014
When and how do seizures kill neurons, and is cell death relevant to epileptogenesis? Advances in experimental medicine and biology\| PubMed ID: 25012371	2014
Progressive, Seizure-Like, Spike-Wave Discharges Are Common in Both Injured and Uninjured Sprague-Dawley Rats: Implications for the Fluid Percussion Injury Model of Post-Traumatic Epilepsy. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 26085641	2015