Sebastien Bonnet

Department of Medicine, Laval University

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 5	2015

Other Publications

Article	Year
Reversal of chronic hypoxia-induced alterations in pulmonary artery smooth muscle electromechanical coupling upon air breathing. Cardiovascular research\| PubMed ID: 11922912	2002
Upregulation of L-type Ca2+ channels in mesenteric and skeletal arteries of SHR. Hypertension\| PubMed ID: 12154116	2002
Dehydroepiandrosterone (DHEA) prevents and reverses chronic hypoxic pulmonary hypertension. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12878719	2003
Role of Ca(2+)-sensitive K(+) channels in the remission phase of pulmonary hypertension in chronic obstructive pulmonary diseases. Cardiovascular research\| PubMed ID: 14613862	2003
Sildenafil alters calcium signaling and vascular tone in pulmonary arteries from chronically hypoxic rats. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 15155272	2004
Preferential expression and function of voltage-gated, O2-sensitive K+ channels in resistance pulmonary arteries explains regional heterogeneity in hypoxic pulmonary vasoconstriction: ionic ... Circulation research\| PubMed ID: 15217912	2004
Chronic hypoxia induces nonreversible right ventricle dysfunction and dysplasia in rats. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 15317673	2004
Dichloroacetate prevents and reverses pulmonary hypertension by inducing pulmonary artery smooth muscle cell apoptosis. Circulation research\| PubMed ID: 15375007	2004
Gene therapy targeting survivin selectively induces pulmonary vascular apoptosis and reverses pulmonary arterial hypertension. The Journal of clinical investigation\| PubMed ID: 15931388	2005
Sildenafil improves alveolar growth and pulmonary hypertension in hyperoxia-induced lung injury. American journal of respiratory and critical care medicine\| PubMed ID: 15947285	2005
Discovery of benzylidenebenzofuran-3(2H)-one (aurones) as inhibitors of tyrosinase derived from human melanocytes. Journal of medicinal chemistry\| PubMed ID: 16392817	2006
Analogues of N-hydroxycinnamoylphenalkylamides as inhibitors of human melanocyte-tyrosinase. Bioorganic & medicinal chemistry letters\| PubMed ID: 16442796	2006
A central role for oxygen-sensitive K+ channels and mitochondria in the specialized oxygen-sensing system. Novartis Foundation symposium\| PubMed ID: 16686435	2006
An abnormal mitochondrial-hypoxia inducible factor-1alpha-Kv channel pathway disrupts oxygen sensing and triggers pulmonary arterial hypertension in fawn hooded rats: similarities to human p... Circulation\| PubMed ID: 16735674	2006
Absence of malonyl coenzyme A decarboxylase in mice increases cardiac glucose oxidation and protects the heart from ischemic injury. Circulation\| PubMed ID: 17030679	2006
A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth. Cancer cell\| PubMed ID: 17222789	2007
Potassium channel diversity in the pulmonary arteries and pulmonary veins: implications for regulation of the pulmonary vasculature in health and during pulmonary hypertension. Pharmacology & therapeutics\| PubMed ID: 17583356	2007
The nuclear factor of activated T cells in pulmonary arterial hypertension can be therapeutically targeted. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17596340	2007
Statin therapy, alone or with rapamycin, does not reverse monocrotaline pulmonary arterial hypertension: the rapamcyin-atorvastatin-simvastatin study. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 17675370	2007
CD36 expression contributes to age-induced cardiomyopathy in mice. Circulation\| PubMed ID: 17967771	2007
Air pollutant emissions from rice straw open field burning in India, Thailand and the Philippines. Environmental pollution (Barking, Essex : 1987)\| PubMed ID: 19201513	2009
Airway delivery of mesenchymal stem cells prevents arrested alveolar growth in neonatal lung injury in rats. American journal of respiratory and critical care medicine\| PubMed ID: 19713449	2009
Dehydroepiandrosterone reverses systemic vascular remodeling through the inhibition of the Akt/GSK3-{beta}/NFAT axis. Circulation\| PubMed ID: 19752325	2009
Dehydroepiandrosterone: A new treatment for vascular remodeling diseases including pulmonary arterial hypertension. Pharmacology & therapeutics\| PubMed ID: 20206649	2010
HIF-1 inhibition decreases systemic vascular remodelling diseases by promoting apoptosis through a hexokinase 2-dependent mechanism. Cardiovascular research\| PubMed ID: 20498255	2010
Fatty acid oxidation and malonyl-CoA decarboxylase in the vascular remodeling of pulmonary hypertension. Science translational medicine\| PubMed ID: 20702857	2010
Tumor necrosis factor inhibitors as novel therapeutic tools for vascular remodeling diseases. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 20709868	2010
Role for miR-204 in human pulmonary arterial hypertension. The Journal of experimental medicine\| PubMed ID: 21321078	2011
Signal transducers and activators of transcription-3/pim1 axis plays a critical role in the pathogenesis of human pulmonary arterial hypertension. Circulation\| PubMed ID: 21382889	2011
RAGE-dependent activation of the oncoprotein Pim1 plays a critical role in systemic vascular remodeling processes. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 21680901	2011
The role of Nogo and the mitochondria-endoplasmic reticulum unit in pulmonary hypertension. Science translational medicine\| PubMed ID: 21697531	2011
From oncoproteins/tumor suppressors to microRNAs, the newest therapeutic targets for pulmonary arterial hypertension. Journal of molecular medicine (Berlin, Germany)\| PubMed ID: 21761156	2011
Pyruvate dehydrogenase inhibition by the inflammatory cytokine TNFα contributes to the pathogenesis of pulmonary arterial hypertension. Journal of molecular medicine (Berlin, Germany)\| PubMed ID: 21809123	2011
Dehydroepiandrosterone inhibits the Src/STAT3 constitutive activation in pulmonary arterial hypertension. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 21890685	2011
Krüppel-like factor 5 contributes to pulmonary artery smooth muscle proliferation and resistance to apoptosis in human pulmonary arterial hypertension. Respiratory research\| PubMed ID: 21951574	2011
Today's and tomorrow's imaging and circulating biomarkers for pulmonary arterial hypertension. Cellular and molecular life sciences : CMLS\| PubMed ID: 22446747	2012
Plumbagin reverses proliferation and resistance to apoptosis in experimental PAH. The European respiratory journal\| PubMed ID: 22496325	2012
Framework for life cycle sustainability assessment of municipal solid waste management systems with an application to a case study in Thailand. Waste management & research : the journal of the International Solid Wastes and Public Cleansing Association, ISWA\| PubMed ID: 22605020	2012
Repeatability and responsiveness of exercise tests in pulmonary arterial hypertension. The European respiratory journal\| PubMed ID: 23100508	2013
Ozone and its potential control strategy for Chon Buri city, Thailand. Journal of the Air & Waste Management Association (1995)\| PubMed ID: 23362760	2012
The emergence of new therapeutic targets in pulmonary arterial hypertension: from now to the near future. Expert review of respiratory medicine\| PubMed ID: 23362814	2013
Critical role for the advanced glycation end-products receptor in pulmonary arterial hypertension etiology. Journal of the American Heart Association\| PubMed ID: 23525442	2013
Uncoupling protein 2 deficiency mimics the effects of hypoxia and endoplasmic reticulum stress on mitochondria and triggers pseudohypoxic pulmonary vascular remodeling and pulmonary hyperten... Circulation research\| PubMed ID: 23652801	2013
Pim-1: A new biomarker in pulmonary arterial hypertension. Pulmonary circulation\| PubMed ID: 23662177	2013
Therapeutic Potential of microRNA Modulation in Pulmonary Arterial Hypertension. Current vascular pharmacology\| PubMed ID: 23713859	2013
Targeting cell motility in pulmonary arterial hypertension. The European respiratory journal\| PubMed ID: 23845719	2014
Signal transduction in the development of pulmonary arterial hypertension. Pulmonary circulation\| PubMed ID: 24015329	2013
STAT3 signaling in pulmonary arterial hypertension. JAK-STAT\| PubMed ID: 24058777	2012
Anti-inflammatory and immunosuppressive agents in PAH. Handbook of experimental pharmacology\| PubMed ID: 24092351	2013
Role for DNA damage signaling in pulmonary arterial hypertension. Circulation\| PubMed ID: 24270264	2014
Effect of pulmonary arterial hypertension-specific therapies on health-related quality of life: a systematic review. Chest\| PubMed ID: 24626791	2014
miRNAs in PAH: biomarker, therapeutic target or both? Drug discovery today\| PubMed ID: 24881781	2014
Apolipoprotein A-I mimetic peptide 4F rescues pulmonary hypertension by inducing microRNA-193-3p. Circulation\| PubMed ID: 24963038	2014
Impaired angiogenesis and peripheral muscle microcirculation loss contribute to exercise intolerance in pulmonary arterial hypertension. American journal of respiratory and critical care medicine\| PubMed ID: 24977625	2014
Vascular remodeling process in pulmonary arterial hypertension, with focus on miR-204 and miR-126 (2013 Grover Conference series). Pulmonary circulation\| PubMed ID: 25006436	2014
Alternatives to the six-minute walk test in pulmonary arterial hypertension. PloS one\| PubMed ID: 25111294	2014
Sirtuin 3 deficiency is associated with inhibited mitochondrial function and pulmonary arterial hypertension in rodents and humans. Cell metabolism\| PubMed ID: 25284742	2014
A miR-208-Mef2 axis drives the decompensation of right ventricular function in pulmonary hypertension. Circulation research\| PubMed ID: 25287062	2015
Skeletal muscle proteomic signature and metabolic impairment in pulmonary hypertension. Journal of molecular medicine (Berlin, Germany)\| PubMed ID: 25548805	2015
Adaptation and Remodelling of the Pulmonary Circulation in Pulmonary Hypertension. The Canadian journal of cardiology\| PubMed ID: 25630876	2015
NOGGIN: a new therapeutic target for PH? Focus on "Noggin Inhibits Hypoxia-Induced Proliferation by Targeting Store-operated Calcium Entry and TRPC Channels". American journal of physiology. Cell physiology\| PubMed ID: 25832472	2015