Andrew G. Elefanty

Murdoch Childrens Research Institute, The Royal Childrens Hospital

Affiliated withThe Royal Childrens Hospital The University of Melbourne Monash University, Clayton

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 11	2015

Other Publications

Article	Year
Characterization of interactions between transcription factors and a regulatory region spanning nt -320 to -281 of the HIV-1 LTR in T-lymphoid and non-T-lymphoid cells. Journal of biomedical science\| PubMed ID: 11810027	2002
Mixl1 is required for axial mesendoderm morphogenesis and patterning in the murine embryo. Development (Cambridge, England)\| PubMed ID: 12117810	2002
The critical regulator of embryonic hematopoiesis, SCL, is vital in the adult for megakaryopoiesis, erythropoiesis, and lineage choice in CFU-S12. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12552125	2003
Retinoic acid induces Pdx1-positive endoderm in differentiating mouse embryonic stem cells. Diabetes\| PubMed ID: 15585742	2005
The primitive streak gene Mixl1 is required for efficient haematopoiesis and BMP4-induced ventral mesoderm patterning in differentiating ES cells. Development (Cambridge, England)\| PubMed ID: 15673572	2005
SCL/Tal-1 is essential for hematopoietic commitment of the hemangioblast but not for its development. Blood\| PubMed ID: 15677567	2005
The hESC line Envy expresses high levels of GFP in all differentiated progeny. Nature methods\| PubMed ID: 15782217	2005
Forced aggregation of defined numbers of human embryonic stem cells into embryoid bodies fosters robust, reproducible hematopoietic differentiation. Blood\| PubMed ID: 15914555	2005
Mixl1 and oct4 proteins are transiently co-expressed in differentiating mouse and human embryonic stem cells. Stem cells and development\| PubMed ID: 16433620	2005
Transcriptional profiling of mouse and human ES cells identifies SLAIN1, a novel stem cell gene. Developmental biology\| PubMed ID: 16546155	2006
A mouse carrying the green fluorescent protein gene targeted to the Pdx1 locus facilitates the study of pancreas development and function. Genesis (New York, N.Y. : 2000)\| PubMed ID: 16794995	2006
A method for genetic modification of human embryonic stem cells using electroporation. Nature protocols\| PubMed ID: 17446878	2007
Differentiation of human embryonic stem cells in serum-free medium reveals distinct roles for bone morphogenetic protein 4, vascular endothelial growth factor, stem cell factor, and fibrobla... Stem cells (Dayton, Ohio)\| PubMed ID: 17556598	2007
Targeting a GFP reporter gene to the MIXL1 locus of human embryonic stem cells identifies human primitive streak-like cells and enables isolation of primitive hematopoietic precursors. Blood\| PubMed ID: 18032708	2008
Building better beta cells. Cell stem cell\| PubMed ID: 18397747	2008
A protocol describing the use of a recombinant protein-based, animal product-free medium (APEL) for human embryonic stem cell differentiation as spin embryoid bodies. Nature protocols\| PubMed ID: 18451785	2008
Expansion of human embryonic stem cells in vitro. Current protocols in stem cell biology\| PubMed ID: 18770627	2008
Directed differentiation of human embryonic stem cells as spin embryoid bodies and a description of the hematopoietic blast colony forming assay. Current protocols in stem cell biology\| PubMed ID: 18770631	2008
Pancreas differentiation of mouse ES cells. Current protocols in stem cell biology\| PubMed ID: 18785172	2007
A protocol for removal of antibiotic resistance cassettes from human embryonic stem cells genetically modified by homologous recombination or transgenesis. Nature protocols\| PubMed ID: 18802436	2008
Enforced expression of Mixl1 during mouse ES cell differentiation suppresses hematopoietic mesoderm and promotes endoderm formation. Stem cells (Dayton, Ohio)\| PubMed ID: 19038793	2009
Pancreatic differentiation from pluripotent stem cells: tweaking the system. Cell research\| PubMed ID: 19339975	2009
Inaugural issue of Stem Cell Research. Stem cell research\| PubMed ID: 19383380	2007
Endocrine cells develop within pancreatic bud-like structures derived from mouse ES cells differentiated in response to BMP4 and retinoic acid. Stem cell research\| PubMed ID: 19383384	2007
ErythRED, a hESC line enabling identification of erythroid cells. Nature methods\| PubMed ID: 19701193	2009
Reshaping pluripotent stem cells. Nature biotechnology\| PubMed ID: 19741639	2009
Generation of human embryonic stem cell reporter knock-in lines by homologous recombination. Current protocols in stem cell biology\| PubMed ID: 19885825	2009
Fourier transform infrared microspectroscopy identifies early lineage commitment in differentiating human embryonic stem cells. Stem cell research\| PubMed ID: 20060373	2010
Differentiating embryonic stem cells pass through 'temporal windows' that mark responsiveness to exogenous and paracrine mesendoderm inducing signals. PloS one\| PubMed ID: 20502661	2010
Expression from a betageo gene trap in the Slain1 gene locus is predominantly associated with the developing nervous system. The International journal of developmental biology\| PubMed ID: 20563991	2010
On the streets of San Francisco: highlights from the ISSCR Annual Meeting 2010. Cell stem cell\| PubMed ID: 20887950	2010
Defined substrates for pluripotent stem cells: are we there yet? Nature methods\| PubMed ID: 21116246	2010
Stage-specific signaling through TGFÎ² family members and WNT regulates patterning and pancreatic specification of human pluripotent stem cells. Development (Cambridge, England)\| PubMed ID: 21270052	2011
A targeted NKX2.1 human embryonic stem cell reporter line enables identification of human basal forebrain derivatives. Stem cells (Dayton, Ohio)\| PubMed ID: 21425409	2011
Generation of human female reproductive tract epithelium from human embryonic stem cells. PloS one\| PubMed ID: 21698266	2011
NKX2-5(eGFP/w) hESCs for isolation of human cardiac progenitors and cardiomyocytes. Nature methods\| PubMed ID: 22020065	2011
SIRPA is a specific cell-surface marker for isolating cardiomyocytes derived from human pluripotent stem cells. Nature biotechnology\| PubMed ID: 22020386	2011
Temporal restriction of pancreatic branching competence during embryogenesis is mirrored in differentiating embryonic stem cells. Stem cells and development\| PubMed ID: 22034992	2012
Brachyury and related Tbx proteins interact with the Mixl1 homeodomain protein and negatively regulate Mixl1 transcriptional activity. PloS one\| PubMed ID: 22164283	2011
PdgfrÎ± and Flk1 are direct target genes of Mixl1 in differentiating embryonic stem cells. Stem cell research\| PubMed ID: 22265737	2012
Generating GABAergic cerebral cortical interneurons from mouse and human embryonic stem cells. Stem cell research\| PubMed ID: 22280980	2012
Efficient generation of adipocytes in a dish. Nature cell biology\| PubMed ID: 22298041	2012
The Mix family of homeobox genes--key regulators of mesendoderm formation during vertebrate development. Developmental biology\| PubMed ID: 22580160	2012
APELIN promotes hematopoiesis from human embryonic stem cells. Blood\| PubMed ID: 22611158	2012
Differentiation of human embryonic stem cells and induced pluripotent stem cells to cardiomyocytes: a methods overview. Circulation research\| PubMed ID: 22821908	2012
Derivation of endothelial cells from human embryonic stem cells in fully defined medium enables identification of lysophosphatidic acid and platelet activating factor as regulators of eNOS l... Stem cell research\| PubMed ID: 23164599	2013
Analysis of mitochondrial function and localisation during human embryonic stem cell differentiation in vitro. PloS one\| PubMed ID: 23284940	2012
Microbioreactor arrays for full factorial screening of exogenous and paracrine factors in human embryonic stem cell differentiation. PloS one\| PubMed ID: 23300662	2012
Human embryonic stem cell derived mesenchymal progenitors express cardiac markers but do not form contractile cardiomyocytes. PloS one\| PubMed ID: 23342164	2013
Generation of megakaryocytic progenitors from human embryonic stem cells in a feeder- and serum-free medium. PloS one\| PubMed ID: 23424635	2013
Fourier transform infrared microspectroscopy reveals unique phenotypes for human embryonic and induced pluripotent stem cell lines and their progeny. Journal of biophotonics\| PubMed ID: 23616434	2014
Directed differentiation and functional maturation of cortical interneurons from human embryonic stem cells. Cell stem cell\| PubMed ID: 23642365	2013
Functional maturation of hPSC-derived forebrain interneurons requires an extended timeline and mimics human neural development. Cell stem cell\| PubMed ID: 23642366	2013
Fourier transform infrared microspectroscopy reveals that tissue culture conditions affect the macromolecular phenotype of human embryonic stem cells. The Analyst\| PubMed ID: 23745179	2013
WNT3A promotes hematopoietic or mesenchymal differentiation from hESCs depending on the time of exposure. Stem cell reports\| PubMed ID: 24052942	2013
The characterisation of pluripotent and multipotent stem cells using Fourier transform infrared microspectroscopy. International journal of molecular sciences\| PubMed ID: 24065090	2013
PGC-1α and reactive oxygen species regulate human embryonic stem cell-derived cardiomyocyte function. Stem cell reports\| PubMed ID: 24371810	2013
Efficient endoderm induction from human pluripotent stem cells by logically directing signals controlling lineage bifurcations. Cell stem cell\| PubMed ID: 24412311	2014
FOXN1 (GFP/w) reporter hESCs enable identification of integrin-β4, HLA-DR, and EpCAM as markers of human PSC-derived FOXN1(+) thymic epithelial progenitors. Stem cell reports\| PubMed ID: 24936476	2014
SIRPA, VCAM1 and CD34 identify discrete lineages during early human cardiovascular development. Stem cell research\| PubMed ID: 24968096	2014
Derivation of insulin-producing beta-cells from human pluripotent stem cells. The review of diabetic studies : RDS\| PubMed ID: 25148364	2014
β-cell regeneration and differentiation: how close are we to the 'holy grail'? Journal of molecular endocrinology\| PubMed ID: 25385843	2014
Efficient Generation of NKX6-1(+) Pancreatic Progenitors from Multiple Human Pluripotent Stem Cell Lines. Stem cell reports\| PubMed ID: 25843049	2015
Productive Infection of Human Embryonic Stem Cell-Derived NKX2.1+ Respiratory Progenitors With Human Rhinovirus. Stem cells translational medicine\| PubMed ID: 25873746	2015
Human definitive haemogenic endothelium and arterial vascular endothelium represent distinct lineages. Nature cell biology\| PubMed ID: 25915127	2015