Ronald B. Tjalkens

Center for Environmental Medicine, Colorado State University

Affiliated withColorado State University

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 6	2015

Other Publications

Article	Year
Manganese potentiates lipopolysaccharide-induced expression of NOS2 in C6 glioma cells through mitochondrial-dependent activation of nuclear factor kappaB. Brain research. Molecular brain research\| PubMed ID: 15010209	2004
CI-1010 induced opening of the mitochondrial permeability transition pore precedes oxidative stress and apoptosis in SY5Y neuroblastoma cells. Brain research\| PubMed ID: 12560110	2003
Prenatal expression of N-acetyltransferases in C57Bl/6 mice. Chemico-biological interactions\| PubMed ID: 12606156	2003
Regional variation in the activation threshold for 1,3-DNB-induced mitochondrial permeability transition in brainstem and cortical astrocytes. Neurotoxicology\| PubMed ID: 12782104	2003
The effects of genetic variation in N-acetyltransferases on 4-aminobiphenyl genotoxicity in mouse liver. Chemico-biological interactions\| PubMed ID: 12902152	2003
The role of docosahexaenoic acid in mediating mitochondrial membrane lipid oxidation and apoptosis in colonocytes. Carcinogenesis\| PubMed ID: 15975958	2005
NF-kappaB-dependent production of nitric oxide by astrocytes mediates apoptosis in differentiated PC12 neurons following exposure to manganese and cytokines. Brain research. Molecular brain research\| PubMed ID: 16168523	2005
Modulation of intercellular calcium signaling by melatonin in avian and mammalian astrocytes is brain region-specific. The Journal of comparative neurology\| PubMed ID: 16261532	2005
Manganese-induced neurotoxicity: the role of astroglial-derived nitric oxide in striatal interneuron degeneration. Toxicological sciences : an official journal of the Society of Toxicology\| PubMed ID: 16551646	2006
Manganese suppresses ATP-dependent intercellular calcium waves in astrocyte networks through alteration of mitochondrial and endoplasmic reticulum calcium dynamics. Brain research\| PubMed ID: 16934782	2006
The peroxisome proliferator-activated receptor-gamma agonist 1,1-bis(3'-indolyl)-1-(p-trifluoromethylphenyl)methane suppresses manganese-induced production of nitric oxide in astrocytes and ... Journal of neuroscience research\| PubMed ID: 18041089	2008
Manganese potentiates nuclear factor-kappaB-dependent expression of nitric oxide synthase 2 in astrocytes by activating soluble guanylate cyclase and extracellular responsive kinase signalin... Journal of neuroscience research\| PubMed ID: 18335517	2008
Nuclear factor kappa-B mediates selective induction of neuronal nitric oxide synthase in astrocytes during low-level inflammatory stimulation with MPTP. Brain research\| PubMed ID: 18508038	2008
Suppression of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced nitric-oxide synthase 2 expression in astrocytes by a novel diindolylmethane analog protects striatal neurons against apop... Molecular pharmacology\| PubMed ID: 18840677	2009
Analysis of targeted mutation in DJ-1 on cellular function in primary astrocytes. Toxicology letters\| PubMed ID: 19063952	2009
Age-dependent susceptibility to manganese-induced neurological dysfunction. Toxicological sciences : an official journal of the Society of Toxicology\| PubMed ID: 19812362	2009
Developmental exposure to manganese increases adult susceptibility to inflammatory activation of glia and neuronal protein nitration. Toxicological sciences : an official journal of the Society of Toxicology\| PubMed ID: 19812365	2009
Toxicological and pathophysiological roles of reactive oxygen and nitrogen species. Toxicology\| PubMed ID: 20643181	2010
Low-dose 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine causes inflammatory activation of astrocytes in nuclear factor-κB reporter mice prior to loss of dopaminergic neurons. Journal of neuroscience research\| PubMed ID: 21259327	2011
Manganese-induced NF-kappaB activation and nitrosative stress is decreased by estrogen in juvenile mice. Toxicological sciences : an official journal of the Society of Toxicology\| PubMed ID: 21512103	2011
1,3-Dinitrobenzene-induced metabolic impairment through selective inactivation of the pyruvate dehydrogenase complex. Toxicological sciences : an official journal of the Society of Toxicology\| PubMed ID: 21551353	2011
Detection of nitric oxide formation in primary neural cells and tissues. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 21815072	2011
Role of oxidative stress and the mitochondrial permeability transition in methylmercury cytotoxicity. Neurotoxicology\| PubMed ID: 21871920	2011
Gene deletion of nos2 protects against manganese-induced neurological dysfunction in juvenile mice. Toxicological sciences : an official journal of the Society of Toxicology\| PubMed ID: 22174044	2012
Manganese inhibits ATP-induced calcium entry through the transient receptor potential channel TRPC3 in astrocytes. Neurotoxicology\| PubMed ID: 23131343	2013
Neuroprotective efficacy and pharmacokinetic behavior of novel anti-inflammatory para-phenyl substituted diindolylmethanes in a mouse model of Parkinson's disease. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 23318470	2013
The atrazine metabolite diaminochlorotriazine suppresses LH release from murine LβT2 cells by suppressing GnRH-induced intracellular calcium transients. Toxicology research\| PubMed ID: 24052811	2013
Repeated exposure to low doses of kainic acid activates nuclear factor kappa B (NF-κB) prior to seizure in transgenic NF-κB/EGFP reporter mice. Neurotoxicology\| PubMed ID: 24813937	2014
Diindolylmethane analogs bind NR4A1 and are NR4A1 antagonists in colon cancer cells. Molecular endocrinology (Baltimore, Md.)\| PubMed ID: 25099012	2014
Domoic acid-induced seizures in California sea lions (Zalophus californianus) are associated with neuroinflammatory brain injury. Aquatic toxicology (Amsterdam, Netherlands)\| PubMed ID: 25286249	2014
Novel para-phenyl substituted diindolylmethanes protect against MPTP neurotoxicity and suppress glial activation in a mouse model of Parkinson's disease. Toxicological sciences : an official journal of the Society of Toxicology\| PubMed ID: 25406165	2015
The Nurr1 Activator 1,1-Bis(3'-Indolyl)-1-(p-Chlorophenyl)Methane Blocks Inflammatory Gene Expression in BV-2 Microglial Cells by Inhibiting Nuclear Factor κB. Molecular pharmacology\| PubMed ID: 25858541	2015
Nuclear receptor 4A (NR4A) family - orphans no more. The Journal of steroid biochemistry and molecular biology\| PubMed ID: 25917081	2015
Angiotensin II regulates brain (pro)renin receptor expression through activation of cAMP response element-binding protein. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 25994957	2015